FI952049A0 - Antimicrobial 5-hydrazino-quinolone derivatives - Google Patents

Antimicrobial 5-hydrazino-quinolone derivatives

Info

Publication number
FI952049A0
FI952049A0 FI952049A FI952049A FI952049A0 FI 952049 A0 FI952049 A0 FI 952049A0 FI 952049 A FI952049 A FI 952049A FI 952049 A FI952049 A FI 952049A FI 952049 A0 FI952049 A0 FI 952049A0
Authority
FI
Finland
Prior art keywords
hydrazino
antimicrobial
quinolone derivatives
quinolone
derivatives
Prior art date
Application number
FI952049A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI952049A (en
Inventor
Jr Thomas Prosser Demuth
Ronald Eugene White
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of FI952049A publication Critical patent/FI952049A/en
Publication of FI952049A0 publication Critical patent/FI952049A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI952049A 1992-10-30 1995-04-28 Antimicrobial 5-hydrazino-quinolone derivatives FI952049A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96896092A 1992-10-30 1992-10-30
PCT/US1993/010091 WO1994010163A1 (en) 1992-10-30 1993-10-22 Antimicrobial 5-hydrazino-quinolone derivatives

Publications (2)

Publication Number Publication Date
FI952049A FI952049A (en) 1995-04-28
FI952049A0 true FI952049A0 (en) 1995-04-28

Family

ID=25514997

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952049A FI952049A0 (en) 1992-10-30 1995-04-28 Antimicrobial 5-hydrazino-quinolone derivatives

Country Status (21)

Country Link
EP (1) EP0666853A1 (en)
JP (1) JPH08502750A (en)
KR (1) KR950704301A (en)
CN (1) CN1064357C (en)
AU (1) AU687018B2 (en)
BR (1) BR9307347A (en)
CA (1) CA2148003A1 (en)
CZ (1) CZ282581B6 (en)
EG (1) EG20543A (en)
FI (1) FI952049A0 (en)
HU (1) HUT72072A (en)
IL (1) IL107323A (en)
MX (1) MX9306814A (en)
NO (1) NO951640L (en)
NZ (1) NZ257470A (en)
PL (1) PL178094B1 (en)
RU (1) RU2126000C1 (en)
SG (1) SG59979A1 (en)
SK (1) SK54795A3 (en)
WO (1) WO1994010163A1 (en)
ZA (1) ZA938089B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
CA2196539C (en) * 1994-08-02 2001-05-15 The Procter & Gamble Company Process for making quinolonyl lactam antimicrobials and novel intermediate compounds
ES2143644T3 (en) * 1994-08-02 2000-05-16 Procter & Gamble PROCEDURE TO PREPARE ANTIMICROBIAL COMPOUNDS.
PT882725E (en) * 1996-02-09 2003-04-30 Toyama Chemical Co Ltd DERIVATIVES OF QUINOLONACARBOXYLIC ACID OR ITS SALTS
JP5279487B2 (en) * 2005-05-18 2013-09-04 エムペックス・ファーマシューティカルズ・インコーポレーテッド Aerosolized fluoroquinolones and uses thereof
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
CA2528849C (en) 2005-06-08 2014-01-14 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents
EA010601B1 (en) * 2005-06-09 2008-10-30 Янссен Фармацевтика Н.В. Quinoline derivatives as antibacterial agents
CN101020647B (en) * 2007-02-14 2011-03-30 杭州师范学院 Synthesis process of beta-cyclopropylamino acrylate
EP2150544B1 (en) 2007-03-19 2016-01-13 Takeda Pharmaceutical Company Limited Mapk/erk kinase inhibitors
KR101601332B1 (en) * 2007-10-05 2016-03-08 센화 바이오사이언시즈 인코포레이티드 Quinolone analogs and methods related thereto
CN102046603B (en) * 2008-06-03 2014-08-13 埃科特莱茵药品有限公司 [4-(1-amino-ethyl)-cyclohexyl]-methyl-amine and [6-(1-amino-ethyl) -tetrahydro-pyran-3-yl]-methyl-amine derivatives as antibacterials
HUE050147T2 (en) 2008-10-07 2020-11-30 Horizon Orphan Llc Inhalation of levofloxacin for reducing lung inflammation
LT2344129T (en) 2008-10-07 2018-05-10 Horizon Orphan Llc Aerosol fluoroquinolone formulations for improved pharmacokinetics
AR076222A1 (en) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd DERIVATIVES 2-HYDROXIETIL-1H-QUINOLIN-ONA AND ITS AZAISOTHERAL ANALOGS WITH ANTIBACTERIAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
BR112012004692B8 (en) 2009-09-04 2021-05-25 Mpex Pharmaceuticals Inc solution comprising levofloxacin for use in a method of treating cystic fibrosis in a human.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
JPH0228178A (en) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd Novel pyridonecarboxylic acid derivative and salt thereof
DE3906365A1 (en) * 1988-07-15 1990-01-18 Bayer Ag 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM
WO1991002526A1 (en) * 1989-08-16 1991-03-07 Pfizer Inc. Azabicyclo quinolone carboxylic acids
WO1991016327A1 (en) * 1990-04-18 1991-10-31 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl lactams
EP0559774B1 (en) * 1990-11-30 1999-07-07 Warner-Lambert Company Individual stereoisomers of 7- 3-(1-aminoalkyl)-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents

Also Published As

Publication number Publication date
AU687018B2 (en) 1998-02-19
SG59979A1 (en) 1999-02-22
MX9306814A (en) 1994-07-29
FI952049A (en) 1995-04-28
BR9307347A (en) 1999-05-25
CN1092773A (en) 1994-09-28
IL107323A0 (en) 1994-01-25
PL308671A1 (en) 1995-08-21
ZA938089B (en) 1994-06-07
NO951640L (en) 1995-06-30
NZ257470A (en) 1997-08-22
CZ282581B6 (en) 1997-08-13
AU5409794A (en) 1994-05-24
WO1994010163A1 (en) 1994-05-11
SK54795A3 (en) 1995-12-06
JPH08502750A (en) 1996-03-26
KR950704301A (en) 1995-11-17
RU95110762A (en) 1997-01-10
NO951640D0 (en) 1995-04-28
HU9501237D0 (en) 1995-06-28
CZ109795A3 (en) 1995-12-13
CN1064357C (en) 2001-04-11
CA2148003A1 (en) 1994-05-11
HUT72072A (en) 1996-03-28
EP0666853A1 (en) 1995-08-16
RU2126000C1 (en) 1999-02-10
IL107323A (en) 2000-06-01
EG20543A (en) 1999-07-31
PL178094B1 (en) 2000-02-29

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