FI940414A - Kinoliini- tai kinatsoliinijohdannaiset, niiden valmistus ja käyttö - Google Patents

Kinoliini- tai kinatsoliinijohdannaiset, niiden valmistus ja käyttö Download PDF

Info

Publication number
FI940414A
FI940414A FI940414A FI940414A FI940414A FI 940414 A FI940414 A FI 940414A FI 940414 A FI940414 A FI 940414A FI 940414 A FI940414 A FI 940414A FI 940414 A FI940414 A FI 940414A
Authority
FI
Finland
Prior art keywords
quinoline
preparation
quinazoline derivatives
integer
nitrogen
Prior art date
Application number
FI940414A
Other languages
English (en)
Swedish (sv)
Other versions
FI940414A0 (fi
Inventor
Takashi Sohda
Haruhiko Makino
Atsuo Baba
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI940414A0 publication Critical patent/FI940414A0/fi
Publication of FI940414A publication Critical patent/FI940414A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
FI940414A 1993-01-28 1994-01-27 Kinoliini- tai kinatsoliinijohdannaiset, niiden valmistus ja käyttö FI940414A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1262893 1993-01-28
JP20612893 1993-08-20

Publications (2)

Publication Number Publication Date
FI940414A0 FI940414A0 (fi) 1994-01-27
FI940414A true FI940414A (fi) 1994-07-29

Family

ID=26348258

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940414A FI940414A (fi) 1993-01-28 1994-01-27 Kinoliini- tai kinatsoliinijohdannaiset, niiden valmistus ja käyttö

Country Status (15)

Country Link
US (3) US5436247A (fi)
EP (1) EP0608870B1 (fi)
KR (1) KR100224135B1 (fi)
CN (1) CN1041520C (fi)
AT (1) ATE205199T1 (fi)
AU (1) AU673213B2 (fi)
CA (1) CA2114300C (fi)
DE (1) DE69428142T2 (fi)
FI (1) FI940414A (fi)
HU (1) HU217907B (fi)
NO (2) NO306992B1 (fi)
NZ (1) NZ250761A (fi)
RU (1) RU2132330C1 (fi)
SG (1) SG50546A1 (fi)
TW (1) TW256832B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW232013B (fi) * 1992-04-24 1994-10-11 Takeda Pharm Industry Co Ltd
NO306992B1 (no) * 1993-01-28 2000-01-24 Takeda Chemical Industries Ltd Quinolinderivater, farmasoeytiske preparater inneholdende forbindelsene og anvendelsen av forbindelsene
ATE188377T1 (de) * 1993-06-29 2000-01-15 Takeda Chemical Industries Ltd Chinoline oder chinazolin-derivate und deren verwendung zur herstellung eines medikaments für die behandlung von osteoporose
EP0749426A1 (en) * 1994-03-08 1996-12-27 Takeda Chemical Industries, Ltd. Quinoline or quinazoline derivatives as anti-inflammatory agents, in particular for treating arthritis
US5641788A (en) * 1994-06-07 1997-06-24 Takeda Chemical Industries, Ltd. Quinoline derivatives and pharmaceutical composition containing them
EP0766681A1 (en) * 1994-06-24 1997-04-09 Takeda Chemical Industries, Ltd. Processes for production of quinoline or quinazoline derivatives and intermediates therefor
US5523312A (en) * 1994-09-27 1996-06-04 Sterling Winthrop Inc. Antipicornaviral agents
WO1996033717A1 (en) * 1995-04-28 1996-10-31 Takeda Chemical Industries, Ltd. Therapeutic composition for arthritis
DE19610882A1 (de) * 1996-03-20 1997-09-25 Dresden Arzneimittel Neue 1,3,5-trisubstituierte Indazol-Derivate mit antiasthmatischer, antiallergischer, entzündungshemmender und immunmodulierender Wirkung, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
CZ298490B6 (cs) * 1997-05-28 2007-10-17 Aventis Pharmaceuticals Inc. Chinolinová a chinoxalinová sloucenina, farmaceutický prostredek obsahující tuto slouceninu, použití této slouceniny a zpusob inhibování aktivity PDGF tyrosin­kinázy in vitro
EP1354603A1 (en) * 2000-12-26 2003-10-22 Takeda Chemical Industries, Ltd. Concomitant drugs
ES2285971T3 (es) * 2002-07-15 2008-11-16 Scinopharm Taiwan, Ltd. Procedimiento para la preparacion de imidazo(1,2-a)piridin-3-acetamidas.
US20060036096A1 (en) * 2002-11-06 2006-02-16 Kensuke Nagashima Process for producing quinolinecarbaldehyde
CA2524221A1 (en) * 2003-04-30 2004-11-18 The Institutes For Pharmaceutical Discovery, Llc Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
US7937406B2 (en) * 2003-09-11 2011-05-03 Oracle America, Inc. Mechanism for automatically establishing a resource grid
DE102004055633A1 (de) * 2004-11-12 2006-05-18 Schering Ag 5-substituierte Chinolin- und Isochinolin-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
AU2007227312A1 (en) * 2006-03-21 2007-09-27 Alza Corporation Hydratable polymeric ester matrix for drug electrotransport
US20100331306A1 (en) 2009-06-25 2010-12-30 Amgen Inc. Heterocyclic compounds and their uses
MX2013005567A (es) * 2010-11-17 2013-10-30 Amgen Inc Derivados de quinolina como inhibidores de pik3.
RU2648247C2 (ru) * 2012-08-24 2018-03-23 Ф. Хоффманн-Ля Рош Аг Бициклические производные пиридина, полезные в качестве ингибитора белков, связывающих жирные кислоты (FABP) 4 и/или 5

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
GB8827822D0 (en) * 1988-11-29 1988-12-29 Janssen Pharmaceutica Nv (1h-azol-1-ylmethyl)substituted quinoline derivatives
CA2002864C (en) * 1988-11-29 1999-11-16 Eddy J. E. Freyne (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives
TW232013B (fi) * 1992-04-24 1994-10-11 Takeda Pharm Industry Co Ltd
NO306992B1 (no) * 1993-01-28 2000-01-24 Takeda Chemical Industries Ltd Quinolinderivater, farmasoeytiske preparater inneholdende forbindelsene og anvendelsen av forbindelsene
EP0766681A1 (en) * 1994-06-24 1997-04-09 Takeda Chemical Industries, Ltd. Processes for production of quinoline or quinazoline derivatives and intermediates therefor

Also Published As

Publication number Publication date
CA2114300C (en) 2000-10-17
US5770602A (en) 1998-06-23
EP0608870A1 (en) 1994-08-03
AU5474294A (en) 1994-08-04
CA2114300A1 (en) 1994-07-29
NO940245L (no) 1994-07-29
SG50546A1 (en) 1998-07-20
ATE205199T1 (de) 2001-09-15
FI940414A0 (fi) 1994-01-27
US5932592A (en) 1999-08-03
DE69428142D1 (de) 2001-10-11
KR100224135B1 (ko) 1999-10-15
CN1041520C (zh) 1999-01-06
NO940245D0 (no) 1994-01-24
US5436247A (en) 1995-07-25
HU9400250D0 (en) 1994-05-30
CN1105363A (zh) 1995-07-19
EP0608870B1 (en) 2001-09-05
TW256832B (fi) 1995-09-11
HUT70194A (en) 1995-09-28
HU217907B (hu) 2000-05-28
NO306992B1 (no) 2000-01-24
RU2132330C1 (ru) 1999-06-27
NZ250761A (en) 1995-03-28
AU673213B2 (en) 1996-10-31
KR940018381A (ko) 1994-08-16
DE69428142T2 (de) 2002-07-04

Similar Documents

Publication Publication Date Title
FI940414A0 (fi) Kinoliini- tai kinatsoliinijohdannaiset, niiden valmistus ja käyttö
FI953968A (fi) Antraniiliset happojohdannaiset
NO904377D0 (no) Tricykliske karbapenemforbindelser.
NO900306D0 (no) Fremgangsmaate for fremstilling av nye pyrazolopyridin-forbindelser.
RU94002335A (ru) Производные хинолина или хиназолина и способ их получения
DE69216509D1 (de) Kondensierte Pyrimidinderivate, ihre Herstellung und ihre Verwendung als Antitumormittel
AU652981B2 (en) Condensed benzoxa ring compound, production thereof, and pharmaceutical composition containing the same
DK1104759T3 (da) Heteroarylphenylpyrazolforbindelser som antiinflammatoriske/analgetiske midler
NO931482L (no) Farmasoeytiske sammensetninger inneholdende quinolin- og quinazolinderivater og nye forbindelser for disse
NO942568L (no) 1-aryloksy-3-alkylamino-2-propanolnitratestere, deres anvendelse og tilsvarende farmasöytiske blanding
ATE173251T1 (de) Kondensierte pyrimidinderivate als antitumorverbindungen
ATE169015T1 (de) Aminobenzoesäure derivate
PT90302A (pt) Processo para a preparacao de derivados de lactamas hetero-tetraciclicas
ATE208761T1 (de) Quinolin-derivate und diese enthaltende pharmazeutische zusammensetzungen
ATE160339T1 (de) Benzimidazolderivate, verfahren zur herstellung, zwischenprodukte, und diese als aktive bestandteile enthaltende antiemetische substanzen
GEP19960472B (en) Method of producing derivative of quinoline or its pharmaceutically acceptable ester, or their salts