FI940191A - New derivatives which are taxol analogues, their preparation and compositions containing them - Google Patents

New derivatives which are taxol analogues, their preparation and compositions containing them Download PDF

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Publication number
FI940191A
FI940191A FI940191A FI940191A FI940191A FI 940191 A FI940191 A FI 940191A FI 940191 A FI940191 A FI 940191A FI 940191 A FI940191 A FI 940191A FI 940191 A FI940191 A FI 940191A
Authority
FI
Finland
Prior art keywords
preparation
compositions containing
new derivatives
taxol analogues
taxol
Prior art date
Application number
FI940191A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI940191A0 (en
Inventor
Jean-Dominique Bourzat
Alain Commercon
Daniel Guenard
Francoise Gueritte-Voegelein
Pierre Potier
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI940191A publication Critical patent/FI940191A/en
Publication of FI940191A0 publication Critical patent/FI940191A0/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI940191A 1991-07-16 1994-01-14 New derivatives, which are taxol analogs, preparation of them and these containing compositions FI940191A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9108937A FR2679230B1 (en) 1991-07-16 1991-07-16 NOVEL DERIVATIVES OF TAXOL ANALOGS, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
PCT/FR1992/000687 WO1993002065A1 (en) 1991-07-16 1992-07-16 New derivatives of taxol analogues, preparation thereof and compositions containing them

Publications (2)

Publication Number Publication Date
FI940191A true FI940191A (en) 1994-01-14
FI940191A0 FI940191A0 (en) 1994-01-14

Family

ID=9415141

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940191A FI940191A0 (en) 1991-07-16 1994-01-14 New derivatives, which are taxol analogs, preparation of them and these containing compositions

Country Status (17)

Country Link
EP (2) EP0524093A1 (en)
JP (1) JPH06509107A (en)
AU (1) AU2388092A (en)
CA (1) CA2113074A1 (en)
CZ (1) CZ9094A3 (en)
FI (1) FI940191A0 (en)
FR (1) FR2679230B1 (en)
HU (1) HUT66600A (en)
IE (1) IE922305A1 (en)
MX (1) MX9204140A (en)
NO (1) NO934723D0 (en)
NZ (1) NZ243548A (en)
SK (1) SK4894A3 (en)
TW (1) TW201740B (en)
WO (1) WO1993002065A1 (en)
YU (1) YU69892A (en)
ZA (1) ZA925245B (en)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495704B1 (en) 1991-09-23 2002-12-17 Florida State University 9-desoxotaxanes and process for the preparation of 9-desoxotaxanes
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5489601A (en) * 1991-09-23 1996-02-06 Florida State University Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them
US6005138A (en) * 1991-09-23 1999-12-21 Florida State University Tricyclic taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5721268A (en) * 1991-09-23 1998-02-24 Florida State University C7 taxane derivatives and pharmaceutical compositions containing them
US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US5998656A (en) * 1991-09-23 1999-12-07 Florida State University C10 tricyclic taxanes
US5739362A (en) * 1991-09-23 1998-04-14 Florida State University Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US5728850A (en) * 1991-09-23 1998-03-17 Florida State University Taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5714513A (en) * 1991-09-23 1998-02-03 Florida State University C10 taxane derivatives and pharmaceutical compositions
US5728725A (en) * 1991-09-23 1998-03-17 Florida State University C2 taxane derivaties and pharmaceutical compositions containing them
US5654447A (en) * 1991-09-23 1997-08-05 Florida State University Process for the preparation of 10-desacetoxybaccatin III
US6028205A (en) * 1991-09-23 2000-02-22 Florida State University C2 tricyclic taxanes
US6335362B1 (en) 1991-09-23 2002-01-01 Florida State University Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
US6011056A (en) * 1991-09-23 2000-01-04 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
US5710287A (en) * 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
US5294637A (en) * 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
US5614549A (en) * 1992-08-21 1997-03-25 Enzon, Inc. High molecular weight polymer-based prodrugs
US5380751A (en) * 1992-12-04 1995-01-10 Bristol-Myers Squibb Company 6,7-modified paclitaxels
US5646176A (en) 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6710191B2 (en) 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
PT687260E (en) * 1993-03-05 2003-07-31 Univ Florida State PROCESS FOR THE PREPARATION OF 9-DEOXOTAXANES
US5547981A (en) * 1993-03-09 1996-08-20 Enzon, Inc. Taxol-7-carbazates
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
PT703909E (en) * 1993-06-11 2000-10-31 Upjohn Co USE OF DELTA-6,7-ANTINEOPLASTIC TAXOES AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
CA2129288C (en) * 1993-08-17 2000-05-16 Jerzy Golik Phosphonooxymethyl esters of taxane derivatives
FR2711370B1 (en) * 1993-10-18 1996-01-05 Rhone Poulenc Rorer Sa New taxoids, their preparation and the pharmaceutical compositions containing them.
US5880131A (en) * 1993-10-20 1999-03-09 Enzon, Inc. High molecular weight polymer-based prodrugs
US5965566A (en) * 1993-10-20 1999-10-12 Enzon, Inc. High molecular weight polymer-based prodrugs
EP0727992A4 (en) * 1993-10-20 2001-01-31 Enzon Inc 2'- and/or 7- substituted taxoids
IL127599A (en) * 1994-01-28 2004-06-01 Upjohn Co Process for preparing isotaxol analogs
AU724499B2 (en) 1996-05-06 2000-09-21 Florida State University 1-deoxy baccatin III, 1-deoxy taxol and 1-deoxy taxol analogs and method for the preparation thereof
JP3942197B2 (en) * 1996-07-15 2007-07-11 株式会社ヤクルト本社 Taxane derivatives and pharmaceuticals containing the same
GB9705903D0 (en) 1997-03-21 1997-05-07 Elliott Gillian D VP22 Proteins and uses thereof
EP1044971A4 (en) * 1997-12-19 2001-11-07 Yakult Honsha Kk Taxane derivatives
AR030188A1 (en) 2000-02-02 2003-08-13 Univ Florida State Res Found TAXANO COMPOUNDS REPLACED WITH ESTERS IN C7; PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND PROCESS TO TREAT A MAMMER SUBJECT THAT SUFFERS FROM A CONDITION THAT RESPONDS TO TAXANS
PL350024A1 (en) 2000-02-02 2002-10-21 Univ Florida State Res Found C7 carbamoyloxy substituted taxanes as antitumor agents
BR0104352A (en) * 2000-02-02 2002-01-02 Univ Florida State Res Found Taxanes substituted by c10 carbamoyloxy as antitumor agents
AU2002365883A1 (en) 2001-11-30 2003-06-17 Bristol-Myers Squibb Company Paclitaxel solvates
US20050187147A1 (en) * 2003-09-22 2005-08-25 Newman Michael J. Compositions and methods for increasing drug efficiency
PA8625301A1 (en) 2004-03-05 2006-06-02 Univ Florida State Res Found TAXANOS WITH SUBSTITUTE LACTILOXILO IN C7
CN104650012A (en) * 2013-11-22 2015-05-27 天士力控股集团有限公司 Taxane compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (en) * 1986-07-17 1988-09-23 Rhone Poulenc Sante TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
IE922305A1 (en) 1993-01-27
EP0524093A1 (en) 1993-01-20
WO1993002065A1 (en) 1993-02-04
YU69892A (en) 1995-10-03
JPH06509107A (en) 1994-10-13
AU2388092A (en) 1993-02-23
EP0596010A1 (en) 1994-05-11
FR2679230B1 (en) 1993-11-19
HU9400113D0 (en) 1994-05-30
FR2679230A1 (en) 1993-01-22
HUT66600A (en) 1994-12-28
MX9204140A (en) 1993-01-01
NZ243548A (en) 1994-07-26
NO934723L (en) 1993-12-20
CZ9094A3 (en) 1994-06-15
NO934723D0 (en) 1993-12-20
ZA925245B (en) 1993-04-28
TW201740B (en) 1993-03-11
FI940191A0 (en) 1994-01-14
CA2113074A1 (en) 1993-02-04
SK4894A3 (en) 1994-12-07

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