FI903429A0 - COMPOUND COMPOSITION OF PEPTIDER MED FOERDROEJD FRIGOERING. - Google Patents

COMPOUND COMPOSITION OF PEPTIDER MED FOERDROEJD FRIGOERING.

Info

Publication number: FI903429A0
Authority: FI; Finland
Prior art keywords: frigoering; foerdroejd; peptider; med; compound composition
Prior art date: 1989-07-07

Application number

FI903429A

Other languages

Finnish (fi)

Other versions

FI108611B (en

Inventor

David Bodmer

Jones Wing Fong

Thomas Kissel

Hawkins Valliant Maulding

Oskar Nagele

Jane Edna Pearson

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-07

Filing date

1990-07-06

Publication date

1990-07-06

1990-07-06 Application filed by Sandoz Ag filed Critical Sandoz Ag

1990-07-06 Publication of FI903429A0 publication Critical patent/FI903429A0/en

1999-05-17 Priority to FI991120A priority Critical patent/FI106926B/en

2002-02-28 Application granted granted Critical

2002-02-28 Publication of FI108611B publication Critical patent/FI108611B/en

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Cosmetics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

FI903429A 1989-07-07 1990-07-06 Process for the preparation of microparticles FI108611B (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
FI991120A FI106926B (en)	1989-07-07	1999-05-17	Process for forming a composition which is released over a long period

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US37702389A	1989-07-07	1989-07-07
US37702389		1989-07-07
US41134789A	1989-09-22	1989-09-22
US41134789		1989-09-22

Publications (2)

Publication Number	Publication Date
FI903429A0 true FI903429A0 (en)	1990-07-06
FI108611B FI108611B (en)	2002-02-28

Family

ID=27007654

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
FI903429A FI108611B (en)	1989-07-07	1990-07-06	Process for the preparation of microparticles
FI20000059A FI109543B (en)	1989-07-07	2000-01-12	A process for the preparation of a therapeutically useful octreotide diphoate
FI20000060A FI109334B (en)	1989-07-07	2000-01-12	A method of forming a sustained release composition

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
FI20000059A FI109543B (en)	1989-07-07	2000-01-12	A process for the preparation of a therapeutically useful octreotide diphoate
FI20000060A FI109334B (en)	1989-07-07	2000-01-12	A method of forming a sustained release composition

Country Status (27)

Country	Link
JP (5)	JPH0832624B2 (en)
KR (2)	KR100303681B1 (en)
AT (1)	AT406225B (en)
AU (2)	AU641407B2 (en)
BE (1)	BE1004486A3 (en)
CA (1)	CA2020477C (en)
CH (1)	CH685230A5 (en)
CY (1)	CY1965A (en)
DE (2)	DE4042752B4 (en)
DK (1)	DK175849B1 (en)
FI (3)	FI108611B (en)
FR (1)	FR2649319A1 (en)
GB (2)	GB2234896B (en)
GR (1)	GR1001121B (en)
HK (2)	HK97695A (en)
HU (2)	HU221294B1 (en)
IE (2)	IE64216B1 (en)
IL (3)	IL131880A (en)
IT (1)	IT1241460B (en)
LU (1)	LU87764A1 (en)
MY (1)	MY106722A (en)
NL (1)	NL195027C (en)
NO (2)	NO302928B1 (en)
NZ (1)	NZ234384A (en)
PT (1)	PT94628B (en)
SE (1)	SE512992C2 (en)
SG (1)	SG26416G (en)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4990336A (en) *	1989-02-08	1991-02-05	Biosearch, Inc.	Sustained release dosage form
YU48420B (en) *	1991-03-25	1998-07-10	Hoechst Aktiengesellschaft	PROCEDURE FOR OBTAINING BIOLOGICAL DEGRADABLE MICROPARTICLES WITH LONG TERM ACTION
CH683149A5 (en) *	1991-07-22	1994-01-31	Debio Rech Pharma Sa	Process for the preparation of microspheres of a biodegradable polymeric material.
US6013853A (en) *	1992-02-14	2000-01-11	The University Of Texas System	Continuous release polymeric implant carrier
US5876452A (en) *	1992-02-14	1999-03-02	Board Of Regents, University Of Texas System	Biodegradable implant
DE4218510A1 (en) *	1992-06-02	1993-12-09	Pharmatech Gmbh	Process for the preparation of biodegradable polyesters
AU4198793A (en) †	1992-07-24	1994-01-27	Takeda Chemical Industries Ltd.	Microparticle preparation and production thereof
JP2944419B2 (en) *	1993-05-10	1999-09-06	ノバルティスアクチエンゲゼルシャフト	Stability of pharmacologically active ingredients in sustained release compositions
US5603960A (en) *	1993-05-25	1997-02-18	O'hagan; Derek T.	Preparation of microparticles and method of immunization
GB9310781D0 (en) *	1993-05-25	1993-07-14	Davis Stanley S	Preparation of microparticles
EP0729357B1 (en)	1993-11-19	2005-02-02	Janssen Pharmaceutica N.V.	Microencapsulated 1,2-benzazoles
AU717113B2 (en)	1995-11-09	2000-03-16	Health Protection Agency	Microencapsulated DNA for vaccination and gene therapy
US6270795B1 (en)	1995-11-09	2001-08-07	Microbiological Research Authority	Method of making microencapsulated DNA for vaccination and gene therapy
DE19545257A1 (en)	1995-11-24	1997-06-19	Schering Ag	Process for the production of morphologically uniform microcapsules and microcapsules produced by this process
US5817343A (en) *	1996-05-14	1998-10-06	Alkermes, Inc.	Method for fabricating polymer-based controlled-release devices
US5968895A (en) *	1996-12-11	1999-10-19	Praecis Pharmaceuticals, Inc.	Pharmaceutical formulations for sustained drug delivery
US6126919A (en) *	1997-02-07	2000-10-03	3M Innovative Properties Company	Biocompatible compounds for pharmaceutical drug delivery systems
GB9810236D0 (en)	1998-05-13	1998-07-08	Microbiological Res Authority	Improvements relating to encapsulation of bioactive agents
US6632457B1 (en) *	1998-08-14	2003-10-14	Incept Llc	Composite hydrogel drug delivery systems
US7107268B1 (en)	1998-11-12	2006-09-12	Printable Technologies, Inc.	Centralized system and method for managing enterprise operations
US6226656B1 (en)	1998-11-12	2001-05-01	Sourcefinder, Inc.	System and method for creating, generating and processing user-defined generic specs
US6204308B1 (en)	1999-03-01	2001-03-20	Novartis Ag	Organic compounds
EP1044683A1 (en) *	1999-04-15	2000-10-18	Debio Recherche Pharmaceutique S.A.	One-step dispersion method for the microencapsulation of water soluble substances
US6461631B1 (en) *	1999-11-16	2002-10-08	Atrix Laboratories, Inc.	Biodegradable polymer composition
KR100392501B1 (en) *	2000-06-28	2003-07-22	동국제약 주식회사	Preparation Method for Sustained Release Microparticles by Multiple Emulsion Method and Micropartic les Thereof
US6824822B2 (en) *	2001-08-31	2004-11-30	Alkermes Controlled Therapeutics Inc. Ii	Residual solvent extraction method and microparticles produced thereby
ES2292634T3 (en)	2000-12-21	2008-03-16	Alrise Biosystems Gmbh	Induced phase transition procedure for the production of microparticles containing active hydrophilic agents.
US20040097419A1 (en) *	2002-11-19	2004-05-20	Holger Petersen	Organic compounds
AR044852A1 (en) *	2003-06-24	2005-10-05	Novartis Ag	A PHARMACEUTICAL COMPOSITION FOR PARENTERAL ADMINISTRATION THAT INCLUDES A SOMATOSTATINE ANALOG
CA2819769C (en) *	2003-07-18	2016-06-28	Oakwood Laboratories, L.L.C.	Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions
MY158342A (en) *	2003-11-14	2016-09-30	Novartis Ag	Pharmaceutical composition
CA2557397A1 (en) *	2004-02-26	2005-09-09	Japan Science And Technology Agency	Protein drug sustained-release microparticle preparation for injection and process for producing the same
DE102004053373A1 (en) *	2004-11-02	2006-05-04	Justus-Liebig-Universität Giessen	Invention relating to nano / meso-fiber anisometric particles in the form of nano / meso-fiber tubes, cables and their curved or branched modifications
KR100741867B1 (en) *	2005-07-05	2007-07-24	전북대학교산학협력단	Preparation method of double-layered sphere using oil-in-water and solvent evaporation
JP2009520727A (en) *	2005-12-22	2009-05-28	ノバルティスアクチエンゲゼルシャフト	Sustained release formulation comprising octreotide and two or more polylactide coglycolide polymers
KR100816065B1 (en)	2006-11-27	2008-03-24	동국제약 주식회사	Preparation method of sustained-release microcapsules having good initial burst inhibiting property and the microcapsules thereby
PL2247282T3 (en)	2008-01-30	2015-03-31	Novartis Ag	Sustained release formulation comprising octreotide and three linear polylactide-co-glycolide polymers
USRE49251E1 (en)	2010-01-04	2022-10-18	Mapi Pharma Ltd.	Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US20120083444A1 (en) *	2010-09-30	2012-04-05	Brenda Perkins	Emulsion Method For Preparing Low Residual Solvent Microparticles
AU2011308893B2 (en) *	2010-09-30	2015-04-23	Evonik Corporation	Method for removing residual organic solvent from microparticles
TW201605488A (en)	2013-10-15	2016-02-16	大塚製藥股份有限公司	Drug for preventing and/or treating polycystic kidney disease
KR102464650B1 (en)	2016-05-03	2022-11-10	엘에스일렉트릭(주)	Current limiting device of circuit breaker
US12097292B2 (en)	2016-08-28	2024-09-24	Mapi Pharma Ltd.	Process for preparing microparticles containing glatiramer acetate
WO2018178973A1 (en)	2017-03-26	2018-10-04	Mapi Pharma Ltd.	Glatiramer depot systems for treating progressive forms of multiple sclerosis

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3773919A (en) *	1969-10-23	1973-11-20	Du Pont	Polylactide-drug mixtures
CH649217A5 (en) *	1977-08-25	1985-05-15	Sandoz Ag	BROMOCRIPTIN CONTAINING MICROCAPSULES.
US4622244A (en) *	1979-09-04	1986-11-11	The Washington University	Process for preparation of microcapsules
US4293539A (en) *	1979-09-12	1981-10-06	Eli Lilly And Company	Controlled release formulations and method of treatment
EP0029579B1 (en) *	1979-11-27	1983-02-16	Sandoz Ag	Polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use
US4389330A (en) *	1980-10-06	1983-06-21	Stolle Research And Development Corporation	Microencapsulation process
PH19942A (en) *	1980-11-18	1986-08-14	Sintex Inc	Microencapsulation of water soluble polypeptides
US4675189A (en) *	1980-11-18	1987-06-23	Syntex (U.S.A.) Inc.	Microencapsulation of water soluble active polypeptides
IE52535B1 (en) *	1981-02-16	1987-12-09	Ici Plc	Continuous release pharmaceutical compositions
EP0092918B1 (en) *	1982-04-22	1988-10-19	Imperial Chemical Industries Plc	Continuous release formulations
CH656884A5 (en) *	1983-08-26	1986-07-31	Sandoz Ag	POLYOLESTERS, THEIR PRODUCTION AND USE.
US4485101A (en) *	1983-10-11	1984-11-27	Administrators Of The Tulane Educational Fund	Peptides
JPH0657658B2 (en) *	1985-04-11	1994-08-03	住友製薬株式会社	Sustained release formulation
JPS60100516A (en) *	1983-11-04	1985-06-04	Takeda Chem Ind Ltd	Preparation of sustained release microcapsule
GB8331158D0 (en) *	1983-11-22	1983-12-29	British Telecomm	Metal/semiconductor deposition
JPS60181029A (en) *	1984-02-29	1985-09-14	Toyo Jozo Co Ltd	Preparation of sustained release preparation
CH660302A5 (en) *	1984-10-17	1987-04-15	Debiopharm Sa	HETEROGENEOUS PHASE MICRO-ENCAPSULATION PROCESS OF WATER-SOLUBLE DRUG SUBSTANCES.
ATE61935T1 (en) *	1985-02-07	1991-04-15	Takeda Chemical Industries Ltd	PROCESS FOR PRODUCTION OF MICROCAPSULES.
US4725577A (en) *	1985-04-25	1988-02-16	Administrators Of The Tulane Educational Fund	Biologically active lysine containing octapeptides
CH665558A5 (en) *	1985-10-09	1988-05-31	Debiopharm Sa	Phase sepn. prodn. of microcapsules for water soluble pharmaceuticals - using fluoro-substd. aliphatic hydrocarbon as non-solvent in the hardening stage
JP2539789B2 (en) *	1986-03-06	1996-10-02	日本原子力研究所	Process for producing sustained-release drug complex composed of polylactone
GB2193891B (en) *	1986-08-18	1990-07-25	Sandoz Ltd	Nasal pharmaceutical composition containing a somatostatin anologue.
JPH0725689B2 (en) *	1986-10-07	1995-03-22	中外製薬株式会社	Sustained-release preparation containing granulocyte colony-stimulating factor
GB2209937B (en) *	1987-09-21	1991-07-03	Depiopharm S A	Water insoluble polypeptides
CH672887A5 (en) *	1987-10-14	1990-01-15	Debiopharm Sa
DE3738228A1 (en) *	1987-11-11	1989-05-24	Hoechst Ag	METHOD FOR PRODUCING BIODEGRADABLE MICRO-CAPSULES OF WATER-SOLUBLE PEPTIDES AND PROTEINS AND MICRO-CAPSULES OBTAINED BY THIS PROCESS
JP2653255B2 (en) *	1990-02-13	1997-09-17	武田薬品工業株式会社	Long-term sustained release microcapsules

1990
- 1990-06-25 HU HU974/90A patent/HU221294B1/en unknown
- 1990-07-03 GB GB9014704A patent/GB2234896B/en not_active Expired - Lifetime
- 1990-07-03 SG SG1995907374A patent/SG26416G/en unknown
- 1990-07-05 CH CH2249/90A patent/CH685230A5/en not_active IP Right Cessation
- 1990-07-05 GR GR900100513A patent/GR1001121B/en not_active IP Right Cessation
- 1990-07-05 IE IE243590A patent/IE64216B1/en not_active IP Right Cessation
- 1990-07-05 NZ NZ234384A patent/NZ234384A/en unknown
- 1990-07-05 NO NO903001A patent/NO302928B1/en not_active IP Right Cessation
- 1990-07-05 SE SE9002364A patent/SE512992C2/en not_active IP Right Cessation
- 1990-07-05 IL IL13188090A patent/IL131880A/en active IP Right Grant
- 1990-07-05 CA CA002020477A patent/CA2020477C/en not_active Expired - Lifetime
- 1990-07-05 DK DK199001625A patent/DK175849B1/en not_active IP Right Cessation
- 1990-07-05 IL IL9498390A patent/IL94983A/en active IP Right Grant
- 1990-07-05 IE IE43894A patent/IE64411B1/en not_active IP Right Cessation
- 1990-07-05 BE BE9000693A patent/BE1004486A3/en not_active IP Right Cessation
- 1990-07-05 IL IL13188190A patent/IL131881A/en active IP Right Grant
- 1990-07-05 AU AU58746/90A patent/AU641407B2/en not_active Expired
- 1990-07-05 FR FR9008718A patent/FR2649319A1/en active Granted
- 1990-07-05 NL NL9001537A patent/NL195027C/en not_active IP Right Cessation
- 1990-07-05 IT IT48113A patent/IT1241460B/en active IP Right Grant
- 1990-07-06 KR KR1019900010224A patent/KR100303681B1/en not_active IP Right Cessation
- 1990-07-06 PT PT94628A patent/PT94628B/en not_active IP Right Cessation
- 1990-07-06 MY MYPI90001133A patent/MY106722A/en unknown
- 1990-07-06 JP JP2177665A patent/JPH0832624B2/en not_active Expired - Lifetime
- 1990-07-06 DE DE4042752A patent/DE4042752B4/en not_active Expired - Lifetime
- 1990-07-06 AT AT0144090A patent/AT406225B/en not_active IP Right Cessation
- 1990-07-06 FI FI903429A patent/FI108611B/en active IP Right Grant
- 1990-07-06 DE DE4021517A patent/DE4021517B4/en not_active Expired - Lifetime
- 1990-07-09 LU LU87764A patent/LU87764A1/en unknown
1993
- 1993-03-25 GB GB9306204A patent/GB2265311B/en not_active Expired - Lifetime
1995
- 1995-04-18 JP JP7116539A patent/JPH07309897A/en active Pending
- 1995-04-18 JP JP7116486A patent/JP2931773B2/en not_active Expired - Lifetime
- 1995-06-15 HK HK97695A patent/HK97695A/en not_active IP Right Cessation
- 1995-06-28 HU HU95P/P00523P patent/HU211602A9/en unknown
- 1995-06-29 AU AU23321/95A patent/AU687553B2/en not_active Expired
- 1995-08-15 JP JP7228646A patent/JPH08198771A/en active Pending
1996
- 1996-10-31 HK HK197496A patent/HK197496A/en not_active IP Right Cessation
1997
- 1997-07-04 CY CY196597A patent/CY1965A/en unknown
1998
- 1998-08-26 NO NO19983923A patent/NO320444B1/en unknown
1999
- 1999-09-14 KR KR1019990039209A patent/KR100442931B1/en not_active IP Right Cessation
2000
- 2000-01-12 FI FI20000059A patent/FI109543B/en active
- 2000-01-12 FI FI20000060A patent/FI109334B/en active
2001
- 2001-01-15 JP JP2001006486A patent/JP2001233897A/en active Pending

Also Published As

Publication number	Publication date
HU211602A9 (en)	1995-12-28
GB2265311B (en)	1994-02-09
NZ234384A (en)	1994-05-26
NL195027B (en)	2003-08-01
DK175849B1 (en)	2005-03-29
IE64411B1 (en)	1995-08-09
CY1965A (en)	1997-07-04
FI109543B (en)	2002-08-30
KR100442931B1 (en)	2004-08-02
AU2332195A (en)	1995-09-07
DE4042752B4 (en)	2009-05-07
FR2649319A1 (en)	1991-01-11
NO302928B1 (en)	1998-05-11
FI20000060A (en)	2000-01-12
HU903974D0 (en)	1990-11-28
GB9014704D0 (en)	1990-08-22
FR2649319B1 (en)	1994-12-09
NL195027C (en)	2003-12-02
LU87764A1 (en)	1992-03-11
IT1241460B (en)	1994-01-17
NL9001537A (en)	1991-02-01
BE1004486A3 (en)	1992-12-01
FI109334B (en)	2002-07-15
NO903001L (en)	1991-01-08
ATA144090A (en)	1999-08-15
GB2234896B (en)	1994-01-19
CH685230A5 (en)	1995-05-15
JPH07285853A (en)	1995-10-31
FI20000059A (en)	2000-01-12
DE4021517B4 (en)	2009-04-09
JPH07309897A (en)	1995-11-28
GB2265311A (en)	1993-09-29
NO320444B1 (en)	2005-12-05
JPH0368511A (en)	1991-03-25
SE9002364L (en)	1991-01-08
PT94628A (en)	1991-03-20
IE64216B1 (en)	1995-07-26
HU221294B1 (en)	2002-09-28
NO903001D0 (en)	1990-07-05
SE512992C2 (en)	2000-06-12
AT406225B (en)	2000-03-27
IE902435A1 (en)	1991-02-13
JP2001233897A (en)	2001-08-28
PT94628B (en)	1997-06-30
SE9002364D0 (en)	1990-07-05
IL131880A (en)	2001-12-23
AU687553B2 (en)	1998-02-26
DK162590A (en)	1991-01-08
AU641407B2 (en)	1993-09-23
AU5874690A (en)	1991-01-10
IT9048113A1 (en)	1992-01-05
DK162590D0 (en)	1990-07-05
JPH08198771A (en)	1996-08-06
KR910002430A (en)	1991-02-25
JPH0832624B2 (en)	1996-03-29
CA2020477A1 (en)	1991-01-08
IT9048113A0 (en)	1990-07-05
FI108611B (en)	2002-02-28
IL94983A (en)	1999-08-17
HK97695A (en)	1995-06-23
GB2234896A (en)	1991-02-20
GB9306204D0 (en)	1993-05-19
CA2020477C (en)	2000-11-21
SG26416G (en)	1995-09-01
HUT54037A (en)	1991-01-28
IL131881A (en)	2001-12-23
GR900100513A (en)	1991-12-10
KR100303681B1 (en)	2002-05-16
IL94983A0 (en)	1991-06-10
HK197496A (en)	1996-11-08
GR1001121B (en)	1993-04-28
NO983923L (en)	1991-01-08
NO983923D0 (en)	1998-08-26
MY106722A (en)	1995-07-31
JP2931773B2 (en)	1999-08-09
DE4021517A1 (en)	1991-01-17

Legal Events

Date	Code	Title	Description
1997-08-27	GB	Transfer or assigment of application	Owner name: NOVARTIS AG
2004-08-31	FG	Patent granted	Owner name: NOVARTIS AG

Publication	Publication Date	Title
FI903429A0 (en)	1990-07-06	COMPOUND COMPOSITION OF PEPTIDER MED FOERDROEJD FRIGOERING.
NO900830D0 (en)	1990-02-21	PROCEDURE FOR THE PREPARATION OF PIPERIDE COMPOUNDS.
NO905255L (en)	1991-06-07	PROCEDURE FOR THE PREPARATION OF HETEROCYCLIC SUBSTITUTED ACYLAMINOTIAZOLES.
FI910976A0 (en)	1991-02-27	COMPOSITION FOR BEHANDLING AV EREKTIL DYSFUNKTION.
BR9007196A (en)	1991-12-10	COMPOSITION
BR8806982A (en)	1989-09-05	STABILIZED COMPOSITION
BR8802017A (en)	1988-11-29	STABILIZED COMPOSITION
SE9000221D0 (en)	1990-01-22	COMPOSITION
NO900742L (en)	1990-08-28	COMPOSITION OF WORK BENEFITS.
BR8900004A (en)	1989-08-15	HERBICIDIC COMPOSITIONS OF QUINOXALINYLOXYPHOPYROPANOATE HETEROCYCLIC-ALCOHYLENE COMPOUNDS
NO163402C (en)	1990-05-23	PROCEDURE FOR THE PREPARATION OF ACYLATED DIKETON COMPOUNDS.
NO905008D0 (en)	1990-11-19	PROCEDURE FOR THE PREPARATION OF HETEROCYCLIC COMPOUNDS.
FI903558A0 (en)	1990-07-13	PROTECTION OF ANTIGENERS.
IT1240773B (en)	1993-12-17	IMPROVEMENT OF POZZOLANIC COMPOSITIONS.
NO904285L (en)	1991-04-04	PROCEDURE FOR THE PREPARATION OF SUBSTITUTED CARBOXYTETRAHYDROISOKINOLINES.
NO892204L (en)	1989-12-04	PROCEDURE FOR THE PREPARATION OF IMIDAZOKINOXALIN COMPOUNDS.
NO903666D0 (en)	1990-08-21	PROCEDURE FOR THE PREPARATION OF PYRROLOKINOL COMPOUNDS.
NO942218D0 (en)	1994-06-13	Process for the preparation of carbonate composition
MX9200872A (en)	1992-09-01	COMPOSITION OF BIS-BIBENZIMIDAZOLE.
NO904535L (en)	1991-04-22	PROCEDURE FOR THE PREPARATION OF PHENOXY-HETEROCYCLIC COMPOUNDS.
NO904060D0 (en)	1990-09-18	PROCEDURE FOR THE PREPARATION OF SUBSTITUTED DIBENZOFURANES.
BR9005424A (en)	1991-09-17	COMPOSITION
NO901422D0 (en)	1990-03-28	PROCEDURE FOR THE PREPARATION OF ALFA-GLUCOSIDASE INHIBITORS.
NO903429D0 (en)	1990-08-03	CONSTRUCTION FOR PROTECTION OF BROENNHEDE.
FI906144A0 (en)	1990-12-13	MODIFICATION OF PLASMINOGENAKTIVATORER.