FI20070521L - Rakeita, tabletteja ja rakeistusmenetelmä - Google Patents

Rakeita, tabletteja ja rakeistusmenetelmä Download PDF

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Publication number
FI20070521L
FI20070521L FI20070521A FI20070521A FI20070521L FI 20070521 L FI20070521 L FI 20070521L FI 20070521 A FI20070521 A FI 20070521A FI 20070521 A FI20070521 A FI 20070521A FI 20070521 L FI20070521 L FI 20070521L
Authority
FI
Finland
Prior art keywords
grains
tablets
granulation process
granulation
Prior art date
Application number
FI20070521A
Other languages
English (en)
Swedish (sv)
Other versions
FI20070521A0 (fi
Inventor
Erkki Heilakka
Giovanni Politi
Original Assignee
Atacama Labs Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38331539&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI20070521(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FI20060990A external-priority patent/FI20060990A0/fi
Priority claimed from FI20061146A external-priority patent/FI20061146A0/fi
Application filed by Atacama Labs Oy filed Critical Atacama Labs Oy
Priority to FI20070521A priority Critical patent/FI20070521L/fi
Publication of FI20070521A0 publication Critical patent/FI20070521A0/fi
Priority to PCT/FI2007/000265 priority patent/WO2008056021A2/en
Priority to CN2007800418114A priority patent/CN101557871B/zh
Priority to GB0909764A priority patent/GB2456989B/en
Priority to US11/979,530 priority patent/US8052999B2/en
Priority to CA2949095A priority patent/CA2949095C/en
Priority to JP2009535758A priority patent/JP5479100B2/ja
Priority to DK07848134.8T priority patent/DK2081669T3/da
Priority to KR1020097009752A priority patent/KR101487565B1/ko
Priority to NO20091714A priority patent/NO347305B1/no
Priority to AU2007316540A priority patent/AU2007316540B2/en
Priority to NZ576368A priority patent/NZ576368A/xx
Priority to BRPI0718761-0A priority patent/BRPI0718761A2/pt
Priority to PL07848134T priority patent/PL2081669T3/pl
Priority to EP07848134.8A priority patent/EP2081669B8/en
Priority to ES07848134T priority patent/ES2703247T3/es
Priority to MX2009004760A priority patent/MX2009004760A/es
Priority to CA2668647A priority patent/CA2668647C/en
Publication of FI20070521L publication Critical patent/FI20070521L/fi
Priority to IL198423A priority patent/IL198423A/en
Priority to US12/580,558 priority patent/US8581134B2/en
Priority to HK10101147.8A priority patent/HK1134916A1/xx
Priority to US12/941,314 priority patent/US8951562B2/en
Priority to US12/977,332 priority patent/US8968788B2/en
Priority to US14/582,664 priority patent/US9700513B2/en
Priority to US15/625,696 priority patent/US10265272B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/22—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by pressing in moulds or between rollers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C7/00—Separating solids from solids by electrostatic effect
    • B03C7/02—Separators
    • B03C7/06—Separators with cylindrical material carriers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
    • B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
    • B07B1/18—Drum screens
    • B07B1/22—Revolving drums
    • B07B1/24—Revolving drums with fixed or moving interior agitators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
    • B07B7/00—Selective separation of solid materials carried by, or dispersed in, gas currents
    • B07B7/06—Selective separation of solid materials carried by, or dispersed in, gas currents by impingement against sieves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
    • B07B7/00—Selective separation of solid materials carried by, or dispersed in, gas currents
    • B07B7/08—Selective separation of solid materials carried by, or dispersed in, gas currents using centrifugal force
    • B07B7/10—Selective separation of solid materials carried by, or dispersed in, gas currents using centrifugal force having air recirculating within the apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B9/00—Making granules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B9/00—Making granules
    • B29B9/16—Auxiliary treatment of granules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/30—Feeding material to presses
    • B30B15/302—Feeding material in particulate or plastic state to moulding presses
    • B30B15/308—Feeding material in particulate or plastic state to moulding presses in a continuous manner, e.g. for roller presses, screw extrusion presses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mechanical Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Glanulating (AREA)
FI20070521A 2006-11-10 2007-07-02 Rakeita, tabletteja ja rakeistusmenetelmä FI20070521L (fi)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FI20070521A FI20070521L (fi) 2006-11-10 2007-07-02 Rakeita, tabletteja ja rakeistusmenetelmä
ES07848134T ES2703247T3 (es) 2006-11-10 2007-11-05 Proceso y aparato para producir gránulos
MX2009004760A MX2009004760A (es) 2006-11-10 2007-11-05 Granulos, tabletas y granulacion.
CA2668647A CA2668647C (en) 2006-11-10 2007-11-05 Granules, tablets and granulation
AU2007316540A AU2007316540B2 (en) 2006-11-10 2007-11-05 Granules, tablets and granulation
NO20091714A NO347305B1 (no) 2006-11-10 2007-11-05 Apparat for tørrgranulering og fremgangsmåte for fremstilling av granuler fra et pulver
EP07848134.8A EP2081669B8 (en) 2006-11-10 2007-11-05 Process and apparatus for for producing granules
GB0909764A GB2456989B (en) 2006-11-10 2007-11-05 Granules, tablets and granulation
US11/979,530 US8052999B2 (en) 2006-11-10 2007-11-05 Granules, tablets and granulation
CA2949095A CA2949095C (en) 2006-11-10 2007-11-05 Granules, tablets and granulation
JP2009535758A JP5479100B2 (ja) 2006-11-10 2007-11-05 粒剤、錠剤および造粒
DK07848134.8T DK2081669T3 (da) 2006-11-10 2007-11-05 Fremgangsmåde og anordning til fremstilling af granulater
KR1020097009752A KR101487565B1 (ko) 2006-11-10 2007-11-05 과립, 정제 및 과립화
PCT/FI2007/000265 WO2008056021A2 (en) 2006-11-10 2007-11-05 Granules, tablets and granulation
CN2007800418114A CN101557871B (zh) 2006-11-10 2007-11-05 颗粒、片剂和制粒
NZ576368A NZ576368A (en) 2006-11-10 2007-11-05 Method for producing tablet granules from powder, and separating fines using a reverse air flow and rotating disc
BRPI0718761-0A BRPI0718761A2 (pt) 2006-11-10 2007-11-05 "método para produzir grândulos a partir de um pó, massa de granulado, processo para preparar um tablete, tablete, aparelho para granulação a seco, dispositivo de fracionamento, e, uso de um aparelho ou dispositivo."
PL07848134T PL2081669T3 (pl) 2006-11-10 2007-11-05 Sposób i urządzenie do wytwarzania granulatu
IL198423A IL198423A (en) 2006-11-10 2009-04-27 Methods for the production of granules, granules produced in dry deficit, tablets and devices and devices for granulation
US12/580,558 US8581134B2 (en) 2006-11-10 2009-10-16 Method and apparatus for dry granulation
HK10101147.8A HK1134916A1 (en) 2006-11-10 2010-02-03 Granules, tablets and granulation
US12/941,314 US8951562B2 (en) 2006-11-10 2010-11-08 Method and apparatus or dry granulation
US12/977,332 US8968788B2 (en) 2006-11-10 2010-12-23 Granules, tablets and granulation
US14/582,664 US9700513B2 (en) 2006-11-10 2014-12-24 Method and apparatus for dry granulation
US15/625,696 US10265272B2 (en) 2006-11-10 2017-06-16 Method and apparatus for dry granulation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20060990A FI20060990A0 (fi) 2006-11-10 2006-11-10 Rakeita, tabletteja ja rakeistusmenetelmä
FI20061146A FI20061146A0 (fi) 2006-11-10 2006-12-21 Rakeita, tabletteja ja rakeistusmenetelmä
FI20070521A FI20070521L (fi) 2006-11-10 2007-07-02 Rakeita, tabletteja ja rakeistusmenetelmä

Publications (2)

Publication Number Publication Date
FI20070521A0 FI20070521A0 (fi) 2007-07-02
FI20070521L true FI20070521L (fi) 2008-05-11

Family

ID=38331539

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20070521A FI20070521L (fi) 2006-11-10 2007-07-02 Rakeita, tabletteja ja rakeistusmenetelmä

Country Status (18)

Country Link
US (2) US8052999B2 (fi)
EP (1) EP2081669B8 (fi)
JP (1) JP5479100B2 (fi)
KR (1) KR101487565B1 (fi)
AU (1) AU2007316540B2 (fi)
BR (1) BRPI0718761A2 (fi)
CA (2) CA2949095C (fi)
DK (1) DK2081669T3 (fi)
ES (1) ES2703247T3 (fi)
FI (1) FI20070521L (fi)
GB (1) GB2456989B (fi)
HK (1) HK1134916A1 (fi)
IL (1) IL198423A (fi)
MX (1) MX2009004760A (fi)
NO (1) NO347305B1 (fi)
NZ (1) NZ576368A (fi)
PL (1) PL2081669T3 (fi)
WO (1) WO2008056021A2 (fi)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
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US8257948B1 (en) 2011-02-17 2012-09-04 Purecircle Usa Method of preparing alpha-glucosyl Stevia composition
US9107436B2 (en) 2011-02-17 2015-08-18 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
US8790730B2 (en) 2005-10-11 2014-07-29 Purecircle Usa Process for manufacturing a sweetener and use thereof
US8318459B2 (en) 2011-02-17 2012-11-27 Purecircle Usa Glucosyl stevia composition
US9386797B2 (en) 2011-02-17 2016-07-12 Purecircle Sdn Bhd Glucosyl stevia composition
US9392799B2 (en) 2011-02-17 2016-07-19 Purecircle Sdn Bhd Glucosyl stevia composition
FI20080352A0 (fi) * 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi korkean lääkepitoisuuden tabletin valmistamiseksi
US8951562B2 (en) * 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
FI20080353A0 (fi) * 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi erittäin korkean lääkepitoisuuden tabletin valmistamiseksi
FI20070521L (fi) * 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
FI20080346A0 (fi) * 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi lisäaineita sisältävän tabletin valmistamiseksi
FI20080355A0 (fi) * 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi metforminia käsittävien tablettien valmistamiseksi
FI20080351A0 (fi) * 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi matalan lääkepitoisuuden tabletin valmistamiseksi
WO2009135946A1 (en) * 2008-05-09 2009-11-12 Atacama Labs Oy Method and apparatus for dry granulation
IT1394597B1 (it) * 2008-11-05 2012-07-05 Politi Granulazione a secco in flusso di gas.
DE102008054586A1 (de) * 2008-12-12 2010-06-17 Basf Se Verfahren zur kontinuierlichen Herstellung von geometrischen Katalysatorformkörpern K
BRPI0925048B8 (pt) 2009-05-07 2021-06-22 Gea Pharma Systems Ltd módulo para produção de comprimidos e método para a produção contínua de comprimidos
CN102470237A (zh) 2009-06-26 2012-05-23 塔里斯生物医药公司 用于可植入药物递送装置的固体药物片剂
MX353094B (es) 2009-11-12 2017-12-19 Purecircle Usa Inc Granulacion de un edulcorante de stevia.
US10696706B2 (en) 2010-03-12 2020-06-30 Purecircle Usa Inc. Methods of preparing steviol glycosides and uses of the same
EP2544538B1 (en) 2010-03-12 2022-06-15 PureCircle USA Inc. High-purity steviol glycosides
SG184851A1 (en) * 2010-04-27 2012-11-29 Bayer Ip Gmbh Orally disintegrating tablet containing acarbose
US9510611B2 (en) 2010-12-13 2016-12-06 Purecircle Sdn Bhd Stevia composition to improve sweetness and flavor profile
MX346137B (es) 2010-12-13 2017-03-08 Purecircle Usa Inc Rebaudiosido d altamente soluble.
WO2012108894A1 (en) 2011-02-10 2012-08-16 Purecircle Usa Stevia composition
US9474296B2 (en) 2011-02-17 2016-10-25 Purecircle Sdn Bhd Glucosyl stevia composition
US11690391B2 (en) 2011-02-17 2023-07-04 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
US9603373B2 (en) 2011-02-17 2017-03-28 Purecircle Sdn Bhd Glucosyl stevia composition
US9894922B2 (en) 2011-05-18 2018-02-20 Purecircle Sdn Bhd Glucosyl rebaudioside C
EP3363808B1 (en) 2011-05-31 2021-02-17 PureCircle USA Inc. Process for the preparation of a stevia composition comprising rebaudioside b
MX341095B (es) 2011-06-03 2016-08-08 Purecircle Usa Composicion de estevia.
US20140199246A1 (en) 2011-06-20 2014-07-17 Purecircle Usa Inc. Stevia composition
US9771434B2 (en) 2011-06-23 2017-09-26 Purecircle Sdn Bhd Products from stevia rebaudiana
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