FI20040270A0 - Hydrazino alcohol derivatives useful as inhibitors of copper containing amine oxidases - Google Patents

Hydrazino alcohol derivatives useful as inhibitors of copper containing amine oxidases

Info

Publication number
FI20040270A0
FI20040270A0 FI20040270A FI20040270A FI20040270A0 FI 20040270 A0 FI20040270 A0 FI 20040270A0 FI 20040270 A FI20040270 A FI 20040270A FI 20040270 A FI20040270 A FI 20040270A FI 20040270 A0 FI20040270 A0 FI 20040270A0
Authority
FI
Finland
Prior art keywords
inhibitors
containing amine
alcohol derivatives
copper containing
derivatives useful
Prior art date
Application number
FI20040270A
Other languages
Finnish (fi)
Swedish (sv)
Inventor
Ferenc Fulop
Laszlo Lazar
Marjo Pihlavisto
Marta Palko
Auni Juhakoski
Anne Marjamaeki
David John Smith
Original Assignee
Biotie Therapies Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotie Therapies Oyj filed Critical Biotie Therapies Oyj
Priority to FI20040270A priority Critical patent/FI20040270A0/en
Publication of FI20040270A0 publication Critical patent/FI20040270A0/en
Priority to PCT/FI2005/050038 priority patent/WO2005080319A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/10—Hydrazines
    • C07C243/22—Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/10—Hydrazines
    • C07C243/12—Hydrazines having nitrogen atoms of hydrazine groups bound to acyclic carbon atoms
    • C07C243/14—Hydrazines having nitrogen atoms of hydrazine groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
    • C07C323/48—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI20040270A 2004-02-20 2004-02-20 Hydrazino alcohol derivatives useful as inhibitors of copper containing amine oxidases FI20040270A0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI20040270A FI20040270A0 (en) 2004-02-20 2004-02-20 Hydrazino alcohol derivatives useful as inhibitors of copper containing amine oxidases
PCT/FI2005/050038 WO2005080319A1 (en) 2004-02-20 2005-02-18 Hydrazino alcohol derivatives useful as inhibitors of copper-containing amine oxidases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20040270A FI20040270A0 (en) 2004-02-20 2004-02-20 Hydrazino alcohol derivatives useful as inhibitors of copper containing amine oxidases

Publications (1)

Publication Number Publication Date
FI20040270A0 true FI20040270A0 (en) 2004-02-20

Family

ID=31725746

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20040270A FI20040270A0 (en) 2004-02-20 2004-02-20 Hydrazino alcohol derivatives useful as inhibitors of copper containing amine oxidases

Country Status (2)

Country Link
FI (1) FI20040270A0 (en)
WO (1) WO2005080319A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007509605A (en) * 2003-05-26 2007-04-19 バイオティ セラピーズ コーポレイション Crystalline protein VAP-1
TWI490214B (en) 2008-05-30 2015-07-01 艾德克 上野股份有限公司 Benzene or thiophene derivative and use thereof as vap-1 inhibitor
UA112154C2 (en) 2009-09-08 2016-08-10 Біоті Терапіс Корп. Use of vap-1 inhibitors for treating fibrotic conditions
AU2014279863A1 (en) 2013-06-12 2016-01-28 Proximagen Limited New therapeutic uses of enzyme inhibitors
EP3131539B1 (en) 2014-04-15 2018-12-05 Pécsi Tudományegyetem Semicarbazide-sensitive amine oxidase inhibitors for use as analgesics in traumatic neuropathy and neurogenic inflammation
WO2015189534A1 (en) 2014-06-12 2015-12-17 Proximagen Limited Vap-1 inhibitors for treating muscular dystrophy
EP3777846A1 (en) 2015-12-07 2021-02-17 BenevolentAI Cambridge Limited Vap-1 inhibitors for treating pain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL360374A1 (en) * 2000-07-05 2004-09-06 Biotie Therapies Corporation Inhibitors of copper-containing amine oxidases
JP2007509605A (en) * 2003-05-26 2007-04-19 バイオティ セラピーズ コーポレイション Crystalline protein VAP-1

Also Published As

Publication number Publication date
WO2005080319A1 (en) 2005-09-01

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