ES8701762A1 - Un procedimiento para preparar nuevos derivados de 5-(w-fe- netilamino-alquil)-4,5,6,7-tetrahidro-tieno-(3,2-c)-piridina - Google Patents

Un procedimiento para preparar nuevos derivados de 5-(w-fe- netilamino-alquil)-4,5,6,7-tetrahidro-tieno-(3,2-c)-piridina

Info

Publication number
ES8701762A1
ES8701762A1 ES548925A ES548925A ES8701762A1 ES 8701762 A1 ES8701762 A1 ES 8701762A1 ES 548925 A ES548925 A ES 548925A ES 548925 A ES548925 A ES 548925A ES 8701762 A1 ES8701762 A1 ES 8701762A1
Authority
ES
Spain
Prior art keywords
compositions containing
same
derivatives
thieno
omega
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548925A
Other languages
English (en)
Other versions
ES548925A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of ES8701762A1 publication Critical patent/ES8701762A1/es
Publication of ES548925A0 publication Critical patent/ES548925A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS DE 5-(V-FENETILAMINO-ALQUIL)-4,5,6,7-TETRAHIDRO-TIENO-(3,2-C)-PIRIDINA, DE FORMULA (I), DONDE N ES UN NUMERO ENTRE 2 Y 5, R1 ES H O UN GRUPO 3,4-DIMETOXIFENILO, R2 ES H, UN ALQUILO DE 1 A 4C O UN GRUPO 4-CIANO-4-(3,4-DIMETOXIFENIL)-5-METILHEXILO Y R3 REPRESENTA DOS O TRES GRUPOS METOXI, Y SUS SALES TERAPEUTICAMENTE ACEPTABLES. CONSISTE EN CONDENSAR UNA 5-(V-CLOROALQUIL)-4,5,6,7-TETRAHIDROTIENO-(3,2-C)-PIRIDINA DE FORMULA (II) EN DONDE N Y R1 SON LOS DEFINIDOS ANTES, CON UN DERIVADO DE FENETILAMINA DE FORMULA (III), A UNA TEMPERATURA DE 90 A 130JC, CON CIRCULACION DE NITROGENO. DE APLICACION COMO AGENTES ANTITROMBOTICOS CON ACTIVIDAD ANTAGONISTA DE CALCIO COMPLEMENTARIA.
ES548925A 1984-11-16 1985-11-15 Un procedimiento para preparar nuevos derivados de 5-(w-fe- netilamino-alquil)-4,5,6,7-tetrahidro-tieno-(3,2-c)-piridina Expired ES8701762A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848429087A GB8429087D0 (en) 1984-11-16 1984-11-16 Thienopyridine derivatives

Publications (2)

Publication Number Publication Date
ES8701762A1 true ES8701762A1 (es) 1986-12-01
ES548925A0 ES548925A0 (es) 1986-12-01

Family

ID=10569875

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548925A Expired ES8701762A1 (es) 1984-11-16 1985-11-15 Un procedimiento para preparar nuevos derivados de 5-(w-fe- netilamino-alquil)-4,5,6,7-tetrahidro-tieno-(3,2-c)-piridina

Country Status (25)

Country Link
US (1) US4681888A (es)
JP (1) JPH06785B2 (es)
AR (1) AR241021A1 (es)
AT (1) AT394559B (es)
BE (1) BE903499A (es)
CA (1) CA1292233C (es)
CH (1) CH665211A5 (es)
DE (1) DE3540529A1 (es)
DK (1) DK158738C (es)
DZ (1) DZ860A1 (es)
ES (1) ES8701762A1 (es)
FI (1) FI81352C (es)
FR (2) FR2573429B1 (es)
GB (1) GB8429087D0 (es)
HK (1) HK10389A (es)
IE (1) IE58591B1 (es)
IT (1) IT1201497B (es)
LU (1) LU86137A1 (es)
MA (1) MA20567A1 (es)
NL (1) NL8502946A (es)
NO (1) NO162072C (es)
OA (1) OA08172A (es)
PT (1) PT81487B (es)
SE (1) SE453505B (es)
ZA (1) ZA858267B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5294621A (en) * 1992-10-07 1994-03-15 Ortho Pharmaceutical Corporation Thieno tetrahydropyridines useful as class III antiarrhythmic agents
US6177443B1 (en) 1997-03-07 2001-01-23 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno[3, 2-C]pyridine derivatives, their preparation and use
JP2001514631A (ja) * 1997-03-07 2001-09-11 ノボ ノルディスク アクティーゼルスカブ ４，５，６，７−テトラヒドロ−チエノ［３，２−ｃ］ピリジン誘導体類、それらの製造方法及び使用
CN102241690B (zh) 2010-05-13 2015-08-12 天津药物研究院 一类含腈基的噻吩并吡啶酯类衍生物、其制备方法和用途
CN101863898B (zh) * 2010-05-26 2011-09-07 天津药物研究院 含哌嗪的噻吩并吡啶酮类衍生物、其制备方法和用途
CN101805355B (zh) * 2010-05-27 2012-07-04 天津药物研究院 一类噻吩并吡啶酮衍生物、其制备方法和用途
EP4135698A4 (en) * 2020-04-17 2024-08-14 Univ Indiana Trustees SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2215948B1 (es) * 1973-02-01 1976-05-14 Centre Etd Ind Pharma
FR2358150A1 (fr) * 1976-07-13 1978-02-10 Parcor Nouvelles thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application
DE2658500C2 (de) * 1976-12-23 1986-10-09 Knoll Ag, 6700 Ludwigshafen Pharmazeutische Präparate mit kardioprotektiver Wirkung
GB1576511A (en) * 1977-03-29 1980-10-08 Parcor Thieno(2,3 - c) and (3,2 - c) pyridines process for their preparation and therapeutic applications thereof
FR2530247B1 (fr) * 1982-07-13 1986-05-16 Sanofi Sa Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique

Also Published As

Publication number Publication date
NL8502946A (nl) 1986-06-16
CH665211A5 (fr) 1988-04-29
NO162072B (no) 1989-07-24
AT394559B (de) 1992-05-11
FR2573309B1 (fr) 1988-11-25
MA20567A1 (fr) 1986-07-01
LU86137A1 (fr) 1986-03-24
SE8505369D0 (sv) 1985-11-13
DE3540529C2 (es) 1992-04-30
FR2573429B1 (fr) 1988-11-25
SE453505B (sv) 1988-02-08
NO162072C (no) 1989-11-01
FR2573429A1 (fr) 1986-05-23
JPH06785B2 (ja) 1994-01-05
DZ860A1 (fr) 2004-09-13
OA08172A (fr) 1987-03-31
FI81352C (fi) 1990-10-10
AR241021A1 (es) 1991-04-30
IE852866L (en) 1986-05-16
PT81487A (en) 1985-12-01
DK158738B (da) 1990-07-09
AR241021A2 (es) 1991-04-30
DK527685A (da) 1986-05-17
JPS61122288A (ja) 1986-06-10
FR2573309A1 (fr) 1986-05-23
DK527685D0 (da) 1985-11-15
DE3540529A1 (de) 1986-05-22
DK158738C (da) 1990-11-26
CA1292233C (en) 1991-11-19
HK10389A (en) 1989-02-10
ES548925A0 (es) 1986-12-01
SE8505369L (sv) 1986-05-17
FI854298A0 (fi) 1985-11-01
PT81487B (pt) 1987-12-30
NO854577L (no) 1986-05-20
FI854298A (fi) 1986-05-17
FI81352B (fi) 1990-06-29
IT8522868A0 (it) 1985-11-15
BE903499A (fr) 1986-04-22
US4681888A (en) 1987-07-21
ATA335685A (de) 1991-10-15
IE58591B1 (en) 1993-10-20
ZA858267B (en) 1986-06-25
IT1201497B (it) 1989-02-02
GB8429087D0 (en) 1984-12-27

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000601