ES8407482A1 - Un procedimiento para la preparacion de nuevos derivados de acidos alquiloxazolilaceticos. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de acidos alquiloxazolilaceticos.

Info

Publication number
ES8407482A1
ES8407482A1 ES522529A ES522529A ES8407482A1 ES 8407482 A1 ES8407482 A1 ES 8407482A1 ES 522529 A ES522529 A ES 522529A ES 522529 A ES522529 A ES 522529A ES 8407482 A1 ES8407482 A1 ES 8407482A1
Authority
ES
Spain
Prior art keywords
alkyloxazolylacetic
pharmaceutical compositions
compositions containing
acid derivative
containing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES522529A
Other languages
English (en)
Other versions
ES522529A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of ES522529A0 publication Critical patent/ES522529A0/es
Publication of ES8407482A1 publication Critical patent/ES8407482A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ACIDO ALQUILOXAZOLILACETICO, DE FORMULA (I), EN LA QUE A ES FENILO O HALOGENOFENILO; R ES ALQUILO C1-5; Y R ES HIDROGENO O ALQUILO C1-3.CONSISTE EN LA REACCION DE CICLACION DESHIDRATANTE DE UN COMPUESTO DE FORMULA (II), EN LA QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE EFECTUA EN UN DISOLVENTE, EN PRESENCIA DE UN AGENTE DESHIDRATANTE, A UNA TEMPERATURA ENTRE C5JC Y 130JC.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES HIPOLIPIDEMICOS.
ES522529A 1982-05-19 1983-05-18 Un procedimiento para la preparacion de nuevos derivados de acidos alquiloxazolilaceticos. Expired ES8407482A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57085282A JPS58201771A (ja) 1982-05-19 1982-05-19 アルキルオキサゾリル酢酸誘導体

Publications (2)

Publication Number Publication Date
ES522529A0 ES522529A0 (es) 1984-09-16
ES8407482A1 true ES8407482A1 (es) 1984-09-16

Family

ID=13854208

Family Applications (1)

Application Number Title Priority Date Filing Date
ES522529A Expired ES8407482A1 (es) 1982-05-19 1983-05-18 Un procedimiento para la preparacion de nuevos derivados de acidos alquiloxazolilaceticos.

Country Status (4)

Country Link
US (1) US4535089A (es)
EP (1) EP0094612A3 (es)
JP (1) JPS58201771A (es)
ES (1) ES8407482A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8531608D0 (en) * 1985-12-23 1986-02-05 Beecham Group Plc Treatment
CA2074933C (en) * 1990-11-30 2002-12-03 Masatoshi Chihiro Thiazole derivatives as active superoxide radical inhibitors
MY128323A (en) 1996-09-30 2007-01-31 Otsuka Pharma Co Ltd Thiazole derivatives for inhibition of cytokine production and of cell adhesion
CN103058946A (zh) * 2012-12-19 2013-04-24 浙江工业大学 一种2,5-二取代噁唑衍生物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3401120A (en) * 1965-10-23 1968-09-10 Gaf Corp Corrosion inhibitors
GB1139940A (en) * 1966-09-30 1969-01-15 Ici Ltd Oxazole derivatives
FI53314C (fi) * 1967-06-14 1978-04-10 Wyeth John & Brother Ltd Foerfarande foer framstaellning av farmaceutiskt anvaendbar 2-(fenyleller p-klorfenyl) oxazol-4-yl (aettiksyra -acetatsalt eller -acetamid)
AR208400A1 (es) * 1974-03-13 1976-12-27 Yoshitomi Pharmaceutical Un metodo para producir nuevos acidos 5-alcoxi-4-oxazolalcanoicos 2-substituidos y sus esteres
JPS57188587A (en) * 1981-05-15 1982-11-19 Tanabe Seiyaku Co Ltd Thienyloxazolylacetic acid derivative and its preparation

Also Published As

Publication number Publication date
ES522529A0 (es) 1984-09-16
US4535089A (en) 1985-08-13
EP0094612A2 (en) 1983-11-23
JPH0357901B2 (es) 1991-09-03
EP0094612A3 (en) 1985-01-23
JPS58201771A (ja) 1983-11-24

Similar Documents

Publication Publication Date Title
IL64905A0 (en) Process for the preparation of 2-penem compounds,novel 2-penem compounds produced thereby and pharmaceutical compositions containing them
ES483767A1 (es) Procedimiento para producir n-arilsulfonil-l-argininamidas
PT77410A (en) Process for the preparation of a fungicidal composition containing substituted 1-hydroxymethyltriazolyl derivatives
ES8504682A1 (es) Un procedimiento para la preparacion de compuestos nitro alifaticos
ES8504817A1 (es) Un procedimiento para preparar compuestos de cefem.
ES8700242A1 (es) Un procedimiento para preparar un derivado de dihidropirida-zinona
GB2116551A (en) New crown ether compounds process for the preparation of the crown ether complex forming agents and ion-selective membrane electrodes containing thee same
ES445661A1 (es) Procedimiento para la preparacion de derivados de acetileno.
ES8407482A1 (es) Un procedimiento para la preparacion de nuevos derivados de acidos alquiloxazolilaceticos.
ES8405013A1 (es) Procedimiento para preparar derivados de tieno-tiazol
JPS57171972A (en) Manufacture of quinoline-4-ones
ES8301931A1 (es) Un procedimiento para la preparacion de nuevos imidazoles.
ES8403891A1 (es) Un procedimiento para la preparacion de un derivado del acido furiloxazolila-cetico
ES8506702A1 (es) Un derivado del acido furiloxazolilacetico
ES475004A1 (es) Un procedimiento para la preparacion de sales de eteres del acido clavulanico
ES481418A1 (es) Un procedimiento para preparar un compuesto de 5,8-dihidro- furo 3,2-b, 1,8-naftiridina
GB2071098B (en) Dibenzocycloheptenylidenes and antiinflammatory compositions
ES8600251A1 (es) Metodo de preparar nuevos 2-acilamino-5-feniletenilbencimidazoles
IL65213A (en) 1,4-benzoxazine derivatives,cyclopent(b)(1,4)oxazine derivatives,their preparation and pharmaceutical compositions containing them
ES8403915A1 (es) Un procedimiento para la preparacion de un derivado de b -lactama.
IE800588L (en) Piperidinothiazolidines
ES470462A1 (es) Procedimiento para producir imidazol-2-carbamatos
ES8305722A1 (es) Un procedimiento para la preparacion de nuevos derivados de tetrahidroisoquinolina (tetrahidroisoquinolina).
ES8602789A1 (es) Procedimiento para preparar derivados de 14-hidroxiimino- eburnano racemicos y opticamente activos
ES8205220A1 (es) Procedimiento para la obtencion de esteres del acido succi- nico de efecto antibacterial y antiprotozoal