ES525358A0 - Procedimiento para la fabricacion de 4-(3-trifluorometilfenil)-1,2,3,6-tetrahidropiridinas - Google Patents

Procedimiento para la fabricacion de 4-(3-trifluorometilfenil)-1,2,3,6-tetrahidropiridinas

Info

Publication number
ES525358A0
ES525358A0 ES525358A ES525358A ES525358A0 ES 525358 A0 ES525358 A0 ES 525358A0 ES 525358 A ES525358 A ES 525358A ES 525358 A ES525358 A ES 525358A ES 525358 A0 ES525358 A0 ES 525358A0
Authority
ES
Spain
Prior art keywords
trifluorometilfenil
tetrahidropiridinas
procedure
manufacture
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES525358A
Other languages
English (en)
Other versions
ES8500264A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of ES8500264A1 publication Critical patent/ES8500264A1/es
Publication of ES525358A0 publication Critical patent/ES525358A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Photoreceptors In Electrophotography (AREA)
ES525358A 1982-08-16 1983-08-12 Procedimiento para la fabricacion de 4-(3-trifluorometilfenil)-1,2,3,6-tetrahidropiridinas Granted ES525358A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8214169A FR2531707A1 (fr) 1982-08-16 1982-08-16 Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques

Publications (2)

Publication Number Publication Date
ES8500264A1 ES8500264A1 (es) 1984-10-01
ES525358A0 true ES525358A0 (es) 1984-10-01

Family

ID=9276890

Family Applications (1)

Application Number Title Priority Date Filing Date
ES525358A Granted ES525358A0 (es) 1982-08-16 1983-08-12 Procedimiento para la fabricacion de 4-(3-trifluorometilfenil)-1,2,3,6-tetrahidropiridinas

Country Status (19)

Country Link
US (1) US4521428A (es)
EP (1) EP0101381B1 (es)
JP (1) JPS5984865A (es)
AT (1) ATE16805T1 (es)
AU (1) AU562789B2 (es)
CA (1) CA1245662A (es)
DE (1) DE3361424D1 (es)
DK (1) DK169269B1 (es)
ES (1) ES525358A0 (es)
FI (1) FI73992C (es)
FR (1) FR2531707A1 (es)
GR (1) GR78690B (es)
IE (1) IE55870B1 (es)
IL (1) IL69348A (es)
NO (1) NO161855C (es)
NZ (1) NZ205269A (es)
PT (1) PT77205B (es)
YU (1) YU44750B (es)
ZA (1) ZA835577B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3438394A1 (de) * 1984-10-19 1986-04-30 Merck Patent Gmbh, 6100 Darmstadt Pyridinderivate
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
FR2650505B1 (fr) * 1989-08-07 1994-06-03 Midy Spa Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
US5266573A (en) * 1989-08-07 1993-11-30 Elf Sanofi Trifluoromethylphenyltetrahydropyridines for the treatment and/or prophylaxis of intestinal motility disorders
US5149817A (en) * 1990-03-05 1992-09-22 Shionogi & Co., Ltd. Teirahydropyridine derivatives
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
US5618822A (en) * 1990-05-23 1997-04-08 Sanofi N-substituted trifluoromethylphenyltetrahydropyridines, process for the preparation thereof, intermediates in said process and pharmaceutical compositions containing them
FR2662442A1 (fr) * 1990-05-23 1991-11-29 Midy Spa Trifluoromethylphenyltetrahydropyridines n-substituees procede pour leur preparation, intermediaires du procede et compositions pharmaceutiques les contenant.
FR2672213B1 (fr) * 1991-02-05 1995-03-10 Sanofi Sa Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres.
FR2690158B1 (fr) * 1992-04-17 1994-07-22 Sanofi Elf Nouveau derive arylpiperidinique, procede pour sa preparation et compositions pharmaceutiques le contenant.
FR2757511B1 (fr) * 1996-12-23 2001-05-04 Sanofi Sa Procede pour la preparation d'un derive de tetrahydropyridine
FR2757510B1 (fr) * 1996-12-23 2000-01-07 Sanofi Sa Forme microparticulaire d'un derive de tetrahydropyridine
US6489334B2 (en) 1996-12-23 2002-12-03 Sanofi-Synthelabo Method for the crystallization of a tetrahydropyridin derivative and resulting crystalline forms
FR2757543B1 (fr) * 1996-12-23 1999-04-02 Sanofi Sa Procede pour la cristallisation d'un derive de tetrahydropyridine et formes cristallines ainsi obtenues
FR2762514B1 (fr) 1997-04-29 1999-10-22 Sanofi Sa Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation
FR2763847B1 (fr) 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
AU2001276716A1 (en) 2000-08-08 2002-02-18 Shionogi And Co., Ltd. Cyclic amine derivatives and use thereof
EP2763847A4 (en) 2011-10-07 2015-08-19 Boral Ip Holdings Australia Pty Ltd INORGANIC POLYMER / ORGANIC POLYMER COMPOSITES AND METHODS FOR PREPARING THE SAME
US9752015B2 (en) 2014-08-05 2017-09-05 Boral Ip Holdings (Australia) Pty Limited Filled polymeric composites including short length fibers
US9988512B2 (en) 2015-01-22 2018-06-05 Boral Ip Holdings (Australia) Pty Limited Highly filled polyurethane composites
WO2016195717A1 (en) 2015-06-05 2016-12-08 Boral Ip Holdings (Australia) Pty Limited Filled polyurethane composites with lightweight fillers
US20170267585A1 (en) 2015-11-12 2017-09-21 Amitabha Kumar Filled polyurethane composites with size-graded fillers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB948071A (en) * 1959-05-01 1964-01-29 May & Baker Ltd New heterocyclic compounds
FR86403E (fr) * 1959-05-01 1966-02-04 May & Baker Ltd Nouveaux dérivés de la phényl-4 pipéridine et leur préparation
GB984364A (en) * 1961-07-28 1965-02-24 May & Baker Ltd Substituted piperidines and tetrahydropyridines
DE2101997A1 (en) * 1971-01-16 1972-08-03 Farbenfabriken Bayer AG, 509öfLeverkusen 1-benzyl-4-subst-tetrahydropyridines - useful as intermediates for pharmaceuticals
FR2416886A1 (fr) * 1978-02-08 1979-09-07 Roussel Uclaf Nouveaux derives de la 3-phenyl-tetrahydropyridine et leurs sels, procedes de preparation et application a titre de medicaments
FR2501682A1 (fr) * 1981-03-11 1982-09-17 Sanofi Sa Trifluoromethylphenylpyridines a activite anorexigene, un procede de preparation et compositions pharmaceutiques en contenant
FR2501506A1 (fr) * 1981-03-11 1982-09-17 Sanofi Sa Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine

Also Published As

Publication number Publication date
EP0101381A1 (fr) 1984-02-22
GR78690B (es) 1984-09-27
FR2531707B1 (es) 1985-01-18
YU44750B (en) 1991-02-28
PT77205A (en) 1983-09-01
YU170683A (en) 1986-06-30
AU1757983A (en) 1984-02-23
DK169269B1 (da) 1994-09-26
ES8500264A1 (es) 1984-10-01
NO832923L (no) 1984-02-17
AU562789B2 (en) 1987-06-18
ATE16805T1 (de) 1985-12-15
IL69348A (en) 1986-09-30
FI73992B (fi) 1987-08-31
JPH0557266B2 (es) 1993-08-23
NZ205269A (en) 1986-06-11
CA1245662A (en) 1988-11-29
FR2531707A1 (fr) 1984-02-17
NO161855C (no) 1989-10-04
PT77205B (en) 1986-03-20
NO161855B (no) 1989-06-26
EP0101381B1 (fr) 1985-12-04
ZA835577B (en) 1984-04-25
IE55870B1 (en) 1991-02-14
FI832930A0 (fi) 1983-08-15
DK371983D0 (da) 1983-08-15
JPS5984865A (ja) 1984-05-16
DE3361424D1 (en) 1986-01-16
IL69348A0 (en) 1983-11-30
FI73992C (fi) 1987-12-10
IE831885L (en) 1984-02-16
FI832930A (fi) 1984-02-17
US4521428A (en) 1985-06-04
DK371983A (da) 1984-02-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040628