ES431516A1 - Procedimiento para la preparacion de 2-(heterdanilmetilo 5,9-beta-dialcohil-6,7- benzonortanos. - Google Patents
Procedimiento para la preparacion de 2-(heterdanilmetilo 5,9-beta-dialcohil-6,7- benzonortanos.Info
- Publication number
- ES431516A1 ES431516A1 ES0431516A ES431516A ES431516A1 ES 431516 A1 ES431516 A1 ES 431516A1 ES 0431516 A ES0431516 A ES 0431516A ES 431516 A ES431516 A ES 431516A ES 431516 A1 ES431516 A1 ES 431516A1
- Authority
- ES
- Spain
- Prior art keywords
- dialcohil
- translation
- procedure
- preparation
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2229695A DE2229695A1 (de) | 1972-06-19 | 1972-06-19 | 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES431516A1 true ES431516A1 (es) | 1976-11-16 |
Family
ID=5848060
Family Applications (8)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES416037A Expired ES416037A1 (es) | 1972-06-19 | 1973-06-18 | Procedimiento para la preparacion de 2-(heteroaril-metil)- 5,9b-dialcohil-6,7-benzomorfanos. |
ES431515A Expired ES431515A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
ES431514A Expired ES431514A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
ES431513A Expired ES431513A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
ES431511A Expired ES431511A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
ES431512A Expired ES431512A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
ES0431516A Expired ES431516A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2-(heterdanilmetilo 5,9-beta-dialcohil-6,7- benzonortanos. |
ES431510A Expired ES431510A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
Family Applications Before (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES416037A Expired ES416037A1 (es) | 1972-06-19 | 1973-06-18 | Procedimiento para la preparacion de 2-(heteroaril-metil)- 5,9b-dialcohil-6,7-benzomorfanos. |
ES431515A Expired ES431515A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
ES431514A Expired ES431514A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
ES431513A Expired ES431513A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
ES431511A Expired ES431511A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
ES431512A Expired ES431512A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES431510A Expired ES431510A1 (es) | 1972-06-19 | 1974-10-30 | Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos. |
Country Status (13)
Country | Link |
---|---|
US (1) | US3931194A (es) |
JP (1) | JPS5711908B2 (es) |
AT (6) | AT328627B (es) |
BE (1) | BE801079A (es) |
CH (9) | CH589648A5 (es) |
DE (1) | DE2229695A1 (es) |
DK (1) | DK136904C (es) |
ES (8) | ES416037A1 (es) |
FR (1) | FR2189056B1 (es) |
GB (1) | GB1433817A (es) |
NL (1) | NL7308483A (es) |
NO (1) | NO137694C (es) |
SE (1) | SE405121B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2437610A1 (de) * | 1974-08-05 | 1976-02-26 | Boehringer Sohn Ingelheim | Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung |
GB1575009A (en) * | 1976-06-21 | 1980-09-17 | Acf Chemiefarma Nv | 6,7-benzomorphan derivatives |
JPS63177704A (ja) * | 1987-01-16 | 1988-07-21 | 松山株式会社 | 農作業機連結装置 |
EP2183229B1 (en) | 2007-07-26 | 2012-04-18 | Vitae Pharmaceuticals, Inc. | Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 |
EP2220048B1 (en) | 2007-11-16 | 2017-01-25 | Boehringer Ingelheim International GmbH | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
CA2708303A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
JP5490020B2 (ja) | 2008-01-24 | 2014-05-14 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状カルバゼート及びセミカルバジドインヒビター |
ATE531696T1 (de) * | 2008-02-12 | 2011-11-15 | Boehringer Ingelheim Int | Harnstoff-derivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung |
CA2715290A1 (en) | 2008-02-15 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
CL2009001058A1 (es) | 2008-05-01 | 2010-09-10 | Vitae Pharmaceuticals Inc | Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras. |
WO2009134400A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
EP2291370B1 (en) | 2008-05-01 | 2013-11-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
US8765780B2 (en) | 2008-05-13 | 2014-07-01 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
EP2324017B1 (en) | 2008-07-25 | 2014-12-31 | Boehringer Ingelheim International GmbH | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 |
WO2010011314A1 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
US8680093B2 (en) | 2009-04-30 | 2014-03-25 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
UY33001A (es) | 2009-11-06 | 2011-05-31 | Boehringer Ingelheim Int | Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina |
US8933072B2 (en) | 2010-06-16 | 2015-01-13 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物 |
JP2014524438A (ja) | 2011-08-17 | 2014-09-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | インデノピリジン誘導体 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1281227A (fr) * | 1958-09-22 | 1962-01-12 | Smith Kline French Lab | Perfectionnements apportés aux procédés pour la préparation de dérivés d'aralcoylbenzomorphane |
BE582575A (es) * | 1958-09-22 | |||
CS166802B2 (es) * | 1971-02-08 | 1976-03-29 | Boehringer Sohn Ingelheim | |
SE392895B (sv) * | 1971-08-24 | 1977-04-25 | Sumitomo Chemical Co | Forfarande for framstellning av bensomorfanderivat och deras salter |
-
1972
- 1972-06-19 DE DE2229695A patent/DE2229695A1/de not_active Withdrawn
-
1973
- 1973-06-05 US US05/367,114 patent/US3931194A/en not_active Expired - Lifetime
- 1973-06-06 AT AT489474*7A patent/AT328627B/de not_active IP Right Cessation
- 1973-06-06 AT AT489974*7A patent/AT329200B/de not_active IP Right Cessation
- 1973-06-06 AT AT489874*7A patent/AT329199B/de not_active IP Right Cessation
- 1973-06-06 AT AT494373A patent/AT325218B/de not_active IP Right Cessation
- 1973-06-06 AT AT489774*7A patent/AT328628B/de not_active IP Right Cessation
- 1973-06-06 AT AT490074*7A patent/AT328629B/de not_active IP Right Cessation
- 1973-06-14 CH CH1041276A patent/CH589648A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041176A patent/CH582697A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041476A patent/CH589649A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1040976A patent/CH583229A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041376A patent/CH582698A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041576A patent/CH583231A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH864373A patent/CH583227A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041076A patent/CH583230A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1040876A patent/CH583228A5/xx not_active IP Right Cessation
- 1973-06-18 BE BE132406A patent/BE801079A/xx unknown
- 1973-06-18 SE SE7308564A patent/SE405121B/xx unknown
- 1973-06-18 JP JP6863473A patent/JPS5711908B2/ja not_active Expired
- 1973-06-18 DK DK336173A patent/DK136904C/da active
- 1973-06-18 GB GB2886973A patent/GB1433817A/en not_active Expired
- 1973-06-18 ES ES416037A patent/ES416037A1/es not_active Expired
- 1973-06-18 NO NO2518/73A patent/NO137694C/no unknown
- 1973-06-19 NL NL7308483A patent/NL7308483A/xx not_active Application Discontinuation
- 1973-06-19 FR FR7322249A patent/FR2189056B1/fr not_active Expired
-
1974
- 1974-10-30 ES ES431515A patent/ES431515A1/es not_active Expired
- 1974-10-30 ES ES431514A patent/ES431514A1/es not_active Expired
- 1974-10-30 ES ES431513A patent/ES431513A1/es not_active Expired
- 1974-10-30 ES ES431511A patent/ES431511A1/es not_active Expired
- 1974-10-30 ES ES431512A patent/ES431512A1/es not_active Expired
- 1974-10-30 ES ES0431516A patent/ES431516A1/es not_active Expired
- 1974-10-30 ES ES431510A patent/ES431510A1/es not_active Expired
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