ES401615A1 - Procedimiento para la obtencion de 1,4-dihidropiridinas a- simetricas. - Google Patents

Procedimiento para la obtencion de 1,4-dihidropiridinas a- simetricas.

Info

Publication number: ES401615A1
Authority: ES; Spain
Prior art keywords: formula; indicated above; ketocarboxylates; meanings indicated; reacted
Prior art date: 1971-04-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES401615A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer AG

Original Assignee

Bayer AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-04-10

Filing date

1972-04-08

Publication date

1975-11-01

1972-04-08 Application filed by Bayer AG filed Critical Bayer AG

1975-11-01 Publication of ES401615A1 publication Critical patent/ES401615A1/es

Status Expired legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)

ES401615A 1971-04-10 1972-04-08 Procedimiento para la obtencion de 1,4-dihidropiridinas a- simetricas. Expired ES401615A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2117572A DE2117572C3 (de)	1971-04-10	1971-04-10	Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Publications (1)

Publication Number	Publication Date
ES401615A1 true ES401615A1 (es)	1975-11-01

Family

ID=5804434

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES401615A Expired ES401615A1 (es)	1971-04-10	1972-04-08	Procedimiento para la obtencion de 1,4-dihidropiridinas a- simetricas.

Country Status (27)

Country	Link
US (1)	US3799936A (es)
JP (1)	JPS5527054B1 (es)
AT (1)	AT316552B (es)
AU (1)	AU459338B2 (es)
BE (1)	BE781879A (es)
BG (4)	BG19374A3 (es)
CA (1)	CA925513A (es)
CH (2)	CH571491A5 (es)
CS (2)	CS177846B2 (es)
DD (1)	DD104519A5 (es)
DE (1)	DE2117572C3 (es)
DK (1)	DK132321C (es)
ES (1)	ES401615A1 (es)
FI (1)	FI55187C (es)
FR (1)	FR2132831B1 (es)
GB (1)	GB1331405A (es)
HU (1)	HU165875B (es)
IE (1)	IE36947B1 (es)
IL (1)	IL39170A (es)
LU (1)	LU65129A1 (es)
NL (1)	NL170140C (es)
NO (1)	NO133711C (es)
PL (2)	PL84571B1 (es)
RO (2)	RO59959A (es)
SE (1)	SE371824B (es)
SU (2)	SU475771A3 (es)
ZA (1)	ZA722355B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3988458A (en) *	1972-03-06	1976-10-26	Bayer Aktiengesellschaft	Bicyclic derivatives of 1,4-dihydropyridine 3,5-carboxylic acid esters
DE2210674C3 (de) *	1972-03-06	1981-09-24	Bayer Ag, 5090 Leverkusen	2-Amino-6-methyl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
US4001258A (en) *	1972-03-06	1977-01-04	Bayer Aktiengesellschaft	2-amino-1,4-dihydropyridine derivatives
US3935223A (en) *	1972-03-06	1976-01-27	Bayer Aktiengesellschaft	2-Amino-1,4-dihydropyridine derivatives
DE2210672C3 (de) *	1972-03-06	1980-03-20	Bayer Ag, 5090 Leverkusen	N-substituierte unsymmetrische 1 ^-Dihydropyridin-S^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
US3917622A (en) *	1972-03-06	1975-11-04	Bayer Ag	2-Amino-1,4-dihydropyridine derivatives
US3857849A (en) *	1973-02-28	1974-12-31	Bayer Ag	2-amino-1,4-dihydropyridine derivatives
US3920823A (en) *	1972-03-06	1975-11-18	Bayer Ag	Use of unsymmetrical esters of n-substituted 1,4-dihydropyridine 3,5-dicarboxylic acid as cardio-vascular agents
DD106832A5 (es) *	1972-03-06	1974-07-05
US3939171A (en) *	1972-03-06	1976-02-17	Bayer Aktiengesellschaft	2-Amino-1,4-dihydropyridine derivatives
US3917619A (en) *	1972-03-06	1975-11-04	Bayer Ag	2-Amino-4,5-dihydropyridine derivatives
US3860601A (en) *	1972-03-06	1975-01-14	Horst Meyer	2,6-diamino-1,4-dihydropyridine derivatives
US3917620A (en) *	1972-03-06	1975-11-04	Bayer Ag	2-Amino-4,5-dihydropyridine derivatives
US3989708A (en) *	1972-08-31	1976-11-02	Bayer Aktiengesellschaft	2-Amino-1,4-dihydropyridine derivatives
DE2242786A1 (de) *	1972-08-31	1974-03-14	Bayer Ag	Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen mit einer carbonylfunktion sowie ihre verwendung als arzneimittel
DE2248150A1 (de) *	1972-09-30	1974-04-04	Bayer Ag	Dihydropyridinpolyester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1409865A (en) *	1973-02-13	1975-10-15	Science Union & Cie	Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
DK152285C (da) *	1975-07-02	1988-10-10	Fujisawa Pharmaceutical Co	Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater
FR2405937A1 (fr) *	1977-10-14	1979-05-11	Labaz	Nouveaux derives de dihydropyridine, leur procede de preparation et leur application
SE429652B (sv) *	1978-06-30	1983-09-19	Haessle Ab	2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
SE7910521L (sv) *	1979-12-20	1981-06-21	Haessle Ab	Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma
JPS60120861A (ja) *	1983-12-02	1985-06-28	Otsuka Pharmaceut Co Ltd	ジヒドロピリジン誘導体
IE57810B1 (en) *	1984-03-27	1993-04-21	Delagrange Lab	1,4-dihydropyridine derivatives,their preparation and their use
JPS6143165A (ja) *	1984-08-07	1986-03-01	Otsuka Pharmaceut Co Ltd	ジヒドロピリジン誘導体の製造法
US5571827A (en) *	1990-03-13	1996-11-05	Sepracor Inc.	Methods and compositions for treating hypertension, angina and other disorders using optically pure s(-) nitrendipine
WO1993009774A1 (en) *	1991-11-18	1993-05-27	G.D. Searle & Co.	2-(4-substituted)phenylmethylene derivatives and methods of use
DE59410255D1 (de) *	1993-12-10	2003-04-17	Bayer Ag	Phenyl-substituierte 1,4-Dihydropyridine mit cerebraler Aktivität
EE03192B1 (et) *	1993-12-10	1999-06-15	Bayer Aktiengesellschaft	Isopropüül-(2-metoksüetüül)-4-(2-kloro-3-tsüanofenüül)-1,4-dihüdro-2,6-dimetüülpüri diin-3,5-dikarboksülaat, selle enantiomeerid ja vaheühend, meetodid nimetatud ühendite valmistamiseks ja kasutamine
DE19727350C1 (de) *	1997-06-27	1999-01-21	Bayer Ag	Verfahren zur Herstellung von Nifedipin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1923990C3 (de) *	1969-05-10	1978-11-23	Bayer Ag	Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern

1971
- 1971-04-10 DE DE2117572A patent/DE2117572C3/de not_active Expired
1972
- 1972-03-09 CH CH345972A patent/CH571491A5/xx not_active IP Right Cessation
- 1972-03-09 CH CH1159775A patent/CH571493A5/xx not_active IP Right Cessation
- 1972-03-27 AU AU40454/72A patent/AU459338B2/en not_active Expired
- 1972-04-05 SU SU1932086A patent/SU475771A3/ru active
- 1972-04-05 SU SU1768162A patent/SU431671A3/ru active
- 1972-04-06 BG BG023740A patent/BG19374A3/xx unknown
- 1972-04-06 FI FI947/72A patent/FI55187C/fi active
- 1972-04-06 BG BG020165A patent/BG20353A3/xx unknown
- 1972-04-06 BG BG023739A patent/BG20106A3/xx unknown
- 1972-04-06 BG BG23738A patent/BG19595A3/xx unknown
- 1972-04-07 JP JP3450672A patent/JPS5527054B1/ja active Pending
- 1972-04-07 AT AT301772A patent/AT316552B/de not_active IP Right Cessation
- 1972-04-07 DD DD162141A patent/DD104519A5/xx unknown
- 1972-04-07 NL NLAANVRAGE7204694,A patent/NL170140C/xx not_active IP Right Cessation
- 1972-04-07 LU LU65129D patent/LU65129A1/xx unknown
- 1972-04-07 DK DK172272A patent/DK132321C/da not_active IP Right Cessation
- 1972-04-07 NO NO1191/72A patent/NO133711C/no unknown
- 1972-04-07 US US00242238A patent/US3799936A/en not_active Expired - Lifetime
- 1972-04-07 ZA ZA722355A patent/ZA722355B/xx unknown
- 1972-04-07 IE IE455/72A patent/IE36947B1/xx unknown
- 1972-04-08 PL PL1972154621A patent/PL84571B1/pl unknown
- 1972-04-08 PL PL1972175387A patent/PL92407B1/pl unknown
- 1972-04-08 ES ES401615A patent/ES401615A1/es not_active Expired
- 1972-04-10 SE SE7204607A patent/SE371824B/xx unknown
- 1972-04-10 GB GB1646372A patent/GB1331405A/en not_active Expired
- 1972-04-10 CA CA139294A patent/CA925513A/en not_active Expired
- 1972-04-10 CS CS3558A patent/CS177846B2/cs unknown
- 1972-04-10 FR FR7212513A patent/FR2132831B1/fr not_active Expired
- 1972-04-10 CS CS2378A patent/CS177821B2/cs unknown
- 1972-04-10 RO RO197270489A patent/RO59959A/ro unknown
- 1972-04-10 IL IL7239170A patent/IL39170A/xx unknown
- 1972-04-10 BE BE781879A patent/BE781879A/xx not_active IP Right Cessation
- 1972-04-10 RO RO197279438A patent/RO63113A/ro unknown
- 1972-04-10 HU HUBA2728A patent/HU165875B/hu unknown

Also Published As

Publication number	Publication date
FI55187C (fi)	1979-06-11
NL170140C (nl)	1982-10-01
SU431671A3 (es)	1974-06-05
AU4045472A (en)	1973-10-04
IL39170A (en)	1975-04-25
CH571491A5 (es)	1976-01-15
CS177821B2 (es)	1977-08-31
NL7204694A (es)	1972-10-12
RO59959A (es)	1976-06-15
DE2117572C3 (de)	1980-03-20
RO63113A (fr)	1978-06-15
CA925513A (en)	1973-05-01
SU475771A3 (ru)	1975-06-30
AT316552B (de)	1974-07-25
US3799936A (en)	1974-03-26
IE36947L (en)	1972-10-10
JPS5527054B1 (es)	1980-07-17
DE2117572B2 (es)	1979-06-28
PL84571B1 (es)	1976-04-30
IL39170A0 (en)	1972-06-28
SE371824B (es)	1974-12-02
IE36947B1 (en)	1977-03-30
CH571493A5 (es)	1976-01-15
NO133711C (es)	1976-06-16
PL92407B1 (es)	1977-04-30
BE781879A (fr)	1972-10-10
DD104519A5 (es)	1974-03-12
LU65129A1 (es)	1972-07-12
BG19595A3 (es)	1975-06-25
NO133711B (es)	1976-03-08
DK132321C (da)	1976-04-26
DK132321B (da)	1975-11-24
FI55187B (fi)	1979-02-28
BG20353A3 (bg)	1975-11-05
BG20106A3 (bg)	1975-10-30
GB1331405A (en)	1973-09-26
NL170140B (nl)	1982-05-03
HU165875B (es)	1974-12-28
ZA722355B (en)	1972-12-27
DE2117572A1 (de)	1972-10-19
FR2132831B1 (es)	1975-12-26
BG19374A3 (bg)	1975-06-15
CS177846B2 (es)	1977-08-31
AU459338B2 (en)	1975-03-05
FR2132831A1 (es)	1972-11-24

Publication	Publication Date	Title
ES401615A1 (es)	1975-11-01	Procedimiento para la obtencion de 1,4-dihidropiridinas a- simetricas.
ES401614A1 (es)	1975-11-01	Procedimiento para la obtencion de 1,4-dihidro - piridin- carboxilatos asimetricos.
ES401616A1 (es)	1975-02-16	Procedimiento para la obtencion de 1,4-dihidropiridin - di-carboxilatos asimetricos.
ES324365A1 (es)	1967-03-16	Procedimiento para la preparacion de alquilenpiperidinas sustituidas.
RO85318B (ro)	1984-10-30	Procedeu pentru prepararea unor derivati de 4-chinolona cu activitate antihipertensiva
ES423826A1 (es)	1976-05-16	Procedimiento para la obtencion de amino-3,4-dihidropiridi-nas.
ES412323A1 (es)	1976-01-01	Procedimiento para la obtencion de 2,6-diaminodihidropiri- dinas.
ES410823A1 (es)	1975-12-16	Procedimiento para la obtencion de oximacarbamatos n-sulfe-nilados.
ES395766A1 (es)	1973-12-01	Procedimiento para la obtencion de derivados de la hidan- toina.
ES434547A1 (es)	1976-12-16	Procedimiento para la obtencion de 3, 6-diamino-3, 4-dihi- dropiridonas-2.
ES274331A1 (es)	1962-06-01	Procedimiento para la preparacion de nuevos compuestos de 1,4-benzodioxano
ES391128A1 (es)	1974-09-01	Procedimiento para la preparacion de nuevos imidazolribosil ciclofosfatos.
ES403446A1 (es)	1975-04-16	Procedimiento para la obtencion de derivados de la oxadia- zolona.
ES389211A1 (es)	1973-06-16	Procedimiento para la obtencion de fenoxi-aminas orto-sus- tituidas.
ES317062A1 (es)	1966-08-01	Procedimiento para la obtencion de compuestos de 2-oxo-1,3-diazadicloalcanicos.
ES326789A1 (es)	1967-03-16	Procedimiento para la obtencion de esteres del acido tiol-o tionotilfosforico o fosfonico.
ES389375A1 (es)	1979-05-01	Procedimiento para la obtencion de 1,4-dihidropiriaparato para revelar una superficie de soporte portadora decargas electricas latentes selectivamentedinas de coronario. retenidas en con- figuracion de imagen.
ES412320A1 (es)	1976-04-16	Procedimiento para la obtencion de esteres de acidos 2-ami-no-4,5 dihidro piridin-3,5 dicar-boxilicos.
ES385857A1 (es)	1973-05-01	Procedimiento para la obtencion de aminas terciarias.
ES294182A1 (es)	1964-06-01	Procedimiento para la obtencion de sulfonamidas
ES400193A1 (es)	1974-12-16	Procedimiento para la preparacion de carbamatos de bis-hi- droximetilpiridina.
ES424470A1 (es)	1976-10-16	Un procedimiento para la preparacion de compuestos hetero- ciclicos del tipo de los pinanopirazoles.
ES413743A1 (es)	1976-01-16	Un procedimiento para la preparacion de compuestos de acidol-alfa-hidrazino-betaf-fenilpropionico.
ES399830A1 (es)	1975-06-16	Procedimiento para la preparacion de fosfonatos de bencilo.
ES329698A1 (es)	1967-08-16	Perfeccionamiento introducido en el procedimiento para la obtencion de fenil-acetonitrilos basicamente sustituidos.