ES396825A1 - Un procedimiento para la preparacion de un acido 5-fenilal-cohil-barbiturico sustituido en la posicion 5. - Google Patents

Un procedimiento para la preparacion de un acido 5-fenilal-cohil-barbiturico sustituido en la posicion 5.

Info

Publication number: ES396825A1
Authority: ES; Spain
Prior art keywords: acid; methyl; hydrogen; diethyl; malonate
Prior art date: 1970-11-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES396825A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kendall Co

Original Assignee

Kendall Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-11-09

Filing date

1971-11-09

Publication date

1974-06-16

1971-11-09 Application filed by Kendall Co filed Critical Kendall Co

1974-06-16 Publication of ES396825A1 publication Critical patent/ES396825A1/es

Status Expired legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 3
230000000202 analgesic effect Effects 0.000 title 1
239000000203 mixture Substances 0.000 title 1
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 9
-1 acetoxymethyl Chemical group 0.000 abstract 9
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 6
125000004177 diethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 6
239000001257 hydrogen Substances 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 6
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 6
150000001875 compounds Chemical class 0.000 abstract 5
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 5
OFOBLEOULBTSOW-UHFFFAOYSA-L Malonate Chemical compound [O-]C(=O)CC([O-])=O OFOBLEOULBTSOW-UHFFFAOYSA-L 0.000 abstract 4
239000002253 acid Substances 0.000 abstract 4
WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical compound O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 abstract 2
239000004202 carbamide Substances 0.000 abstract 2
DCFKHNIGBAHNSS-UHFFFAOYSA-N chloro(triethyl)silane Chemical compound CC[Si](Cl)(CC)CC DCFKHNIGBAHNSS-UHFFFAOYSA-N 0.000 abstract 2
IJOOHPMOJXWVHK-UHFFFAOYSA-N chlorotrimethylsilane Chemical compound C[Si](C)(C)Cl IJOOHPMOJXWVHK-UHFFFAOYSA-N 0.000 abstract 2
125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 2
125000003884 phenylalkyl group Chemical group 0.000 abstract 2
QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 abstract 2
ORHQIJMZZRVZPD-UHFFFAOYSA-N 1,1-dimethoxy-3-methylurea Chemical compound CNC(=O)N(OC)OC ORHQIJMZZRVZPD-UHFFFAOYSA-N 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
OJAOWGCGDRGMIW-UHFFFAOYSA-N C(C)(=O)ON(C(=O)NC)OC(C)=O Chemical compound C(C)(=O)ON(C(=O)NC)OC(C)=O OJAOWGCGDRGMIW-UHFFFAOYSA-N 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical group CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
MGJKQDOBUOMPEZ-UHFFFAOYSA-N N,N'-dimethylurea Chemical compound CNC(=O)NC MGJKQDOBUOMPEZ-UHFFFAOYSA-N 0.000 abstract 1
150000001263 acyl chlorides Chemical class 0.000 abstract 1
229940125717 barbiturate Drugs 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
239000007795 chemical reaction product Substances 0.000 abstract 1
239000000460 chlorine Chemical group 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
BEPAFCGSDWSTEL-UHFFFAOYSA-N dimethyl malonate Chemical compound COC(=O)CC(=O)OC BEPAFCGSDWSTEL-UHFFFAOYSA-N 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
UUSXSNJAQDJKCG-UHFFFAOYSA-N iodo(methoxy)methane Chemical compound COCI UUSXSNJAQDJKCG-UHFFFAOYSA-N 0.000 abstract 1
INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 abstract 1
239000011968 lewis acid catalyst Substances 0.000 abstract 1
SIAPCJWMELPYOE-UHFFFAOYSA-N lithium hydride Chemical compound [LiH] SIAPCJWMELPYOE-UHFFFAOYSA-N 0.000 abstract 1
229910000103 lithium hydride Inorganic materials 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
150000007524 organic acids Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
239000005051 trimethylchlorosilane Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
- C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- C07D239/62—Barbituric acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Making Paper Articles (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

ES396825A 1970-11-09 1971-11-09 Un procedimiento para la preparacion de un acido 5-fenilal-cohil-barbiturico sustituido en la posicion 5. Expired ES396825A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US8819370A	1970-11-09	1970-11-09

Publications (1)

Publication Number	Publication Date
ES396825A1 true ES396825A1 (es)	1974-06-16

Family

ID=22209926

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES396825A Expired ES396825A1 (es)	1970-11-09	1971-11-09	Un procedimiento para la preparacion de un acido 5-fenilal-cohil-barbiturico sustituido en la posicion 5.

Country Status (16)

Country	Link
JP (1)	JPS554099B1 (es)
AR (2)	AR194578A1 (es)
AT (1)	AT321937B (es)
AU (1)	AU462551B2 (es)
BE (1)	BE775117A (es)
CH (1)	CH568987A5 (es)
DE (1)	DE2155469C2 (es)
DK (1)	DK135283B (es)
ES (1)	ES396825A1 (es)
FR (1)	FR2112555B1 (es)
GB (1)	GB1322640A (es)
IL (1)	IL38094A (es)
LU (1)	LU64226A1 (es)
NL (1)	NL174042C (es)
NO (1)	NO133497C (es)
SE (1)	SE385887B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3894023A (en) *	1973-07-12	1975-07-08	Kendall & Co	5-Pivaloyloxy-5-(1-phenylethyl) barbituric acid
IT1196500B (it) *	1986-07-16	1988-11-16	Eniricerche Spa	Derivati dell'acido malonico e metodi per la loro sintesi
DE69918662T2 (de)	1998-11-04	2005-08-11	Basell Poliolefine Italia S.P.A.	Bestandteile und katalysatoren für die olefinpolymerisation

1971
- 1971-10-28 AR AR238748A patent/AR194578A1/es active
- 1971-11-02 GB GB5089371A patent/GB1322640A/en not_active Expired
- 1971-11-08 NO NO4117/71A patent/NO133497C/no unknown
- 1971-11-08 SE SE7114224A patent/SE385887B/xx unknown
- 1971-11-08 IL IL38094A patent/IL38094A/xx unknown
- 1971-11-08 DE DE2155469A patent/DE2155469C2/de not_active Expired
- 1971-11-08 LU LU64226D patent/LU64226A1/xx unknown
- 1971-11-09 CH CH1628471A patent/CH568987A5/xx not_active IP Right Cessation
- 1971-11-09 NL NLAANVRAGE7115404,A patent/NL174042C/xx not_active IP Right Cessation
- 1971-11-09 JP JP8875071A patent/JPS554099B1/ja active Pending
- 1971-11-09 BE BE775117A patent/BE775117A/xx not_active IP Right Cessation
- 1971-11-09 FR FR7140132A patent/FR2112555B1/fr not_active Expired
- 1971-11-09 DK DK548371AA patent/DK135283B/da unknown
- 1971-11-09 AT AT963871A patent/AT321937B/de not_active IP Right Cessation
- 1971-11-09 ES ES396825A patent/ES396825A1/es not_active Expired
- 1971-11-09 AU AU35494/71A patent/AU462551B2/en not_active Expired
1973
- 1973-06-05 AR AR248425A patent/AR194697A1/es active

Also Published As

Publication number	Publication date
LU64226A1 (es)	1972-05-29
DE2155469C2 (de)	1984-08-23
IL38094A0 (en)	1972-01-27
IL38094A (en)	1975-11-25
NO133497B (es)	1976-02-02
NL174042C (nl)	1984-04-16
FR2112555A1 (es)	1972-06-16
DE2155469A1 (de)	1972-05-10
NO133497C (es)	1976-05-12
AR194697A1 (es)	1973-07-31
NL7115404A (es)	1972-05-12
JPS554099B1 (es)	1980-01-29
BE775117A (fr)	1972-03-01
DK135283B (da)	1977-03-28
AU3549471A (en)	1973-05-17
CH568987A5 (es)	1975-11-14
SE385887B (sv)	1976-07-26
NL174042B (nl)	1983-11-16
AT321937B (de)	1975-04-25
AR194578A1 (es)	1973-07-31
DK135283C (es)	1977-09-05
FR2112555B1 (es)	1975-12-26
AU462551B2 (en)	1975-06-26
GB1322640A (en)	1973-07-11

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ES319508A1 (es)	1966-07-01	Procedimiento para producir derivados de acido alquenilsuccinico.
ES396825A1 (es)	1974-06-16	Un procedimiento para la preparacion de un acido 5-fenilal-cohil-barbiturico sustituido en la posicion 5.
ES421067A1 (es)	1976-04-01	Procedimiento para la preparacion de nuevas 2-fenilamino- imidazolinas sustituidas.
GB980778A (en)	1965-01-20	Process for the production of methyl-(hydroxymethyl)-siloxanes
ES443182A1 (es)	1977-04-16	Procedimiento para la preparacion de esteres del acido ci- clopropanocarboxilico.
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ES445322A1 (es)	1977-06-01	Un procedimiento para la preparacion de derivados del acido para-isobutil-fenilacetico.
ES397453A1 (es)	1975-03-16	Procedimiento para la preparacion de derivados de imidazo- lina.
ES440282A1 (es)	1977-03-16	Procedimiento para la preparacion de piperidina.
GB758382A (en)	1956-10-03	Improvements in bis-(ú-aminophenoxy) alkane derivatives
ES401342A1 (es)	1975-02-16	Procedimiento para la preparacion de nuevos derivados de lapiridina y de sus sales.
ES394679A1 (es)	1974-02-16	Procedimiento para la preparacion de esteres de acido 1,2, 3,6 - tetrahidro-4-piridilmetil-carboxilixo.
ES437040A1 (es)	1977-01-16	Un procedimiento para preparar un derivado de ftalazona.
ES420666A1 (es)	1976-09-01	Procedimiento para preparar derivados de acidos (1-metil-5-nitro-2-imidazolil)tioalcanoicos.
ES397037A1 (es)	1975-03-01	Metodo de preparar compuestos intermedios para la produc- cion de derivados de azucar de purina.
GB1131598A (en)	1968-10-23	Inosine acetals
ES441880A1 (es)	1977-04-01	Un procedimiento de preparacion de derivados de acidos 2- hidroximetil-tiazol-5-carboxilicos.
ES450876A1 (es)	1977-12-01	Un procedimiento para la preparacion de trans-2, 3, 4, 4-a, 9, 9-a-hexahidro-9-fenil-1h-pirido (3, 4, b) indol.
ES424558A1 (es)	1976-05-16	Procedimiento para la obtencion de derivados carboxilicos.
ES423976A1 (es)	1976-06-16	Procedimiento para la preparacion de nuevas bencilaminas.