ES369853A1 - Procedure for the obtaining of derivatives of the epsilon-amino-caproico acid. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of derivatives of the epsilon-amino-caproico acid. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES369853A1 ES369853A1 ES369853A ES369853A ES369853A1 ES 369853 A1 ES369853 A1 ES 369853A1 ES 369853 A ES369853 A ES 369853A ES 369853 A ES369853 A ES 369853A ES 369853 A1 ES369853 A1 ES 369853A1
- Authority
- ES
- Spain
- Prior art keywords
- coo
- formula
- acid
- translation
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Procedure for obtaining derivatives of ε -aminocaproic acid, which correspond to the general formula R1-CO-NH-CH2-CH2-CH2-CH2-CH2-COO.R2 in which: R1 represents an alkyl, aryl or aralkyl radical (which, in turn, may or may not have substituents of different nature, such as hydroxy halogens) that meet one of the following conditions: a) have a heterocyclic nucleus, b) have 6 or more than 6 carbon atoms, and, R2 can be hydrogen, an alkali or alkaline earth metal, such as lithium, sodium, potassium, magnesium or calcium, or a lower alkyl radical, that is, with less than five carbon atoms, characterized in that they are obtained by reacting an ester of the ε -aminocaproic acid of structural formula M2- (CH2) 5-COO.R2 with an ester of structural formula R1-COO.R3 giving a reaction product of formula R1-CO-NH- (CH2) 5-COO.R2 which is reacted with alkali, giving the reaction product of formula R1-CO-NH- (CH2) 5-COOme which is reacted with a mineral acid to give products of the general formula R1-CO-NH- (CH2) 5-COOH in whose formulas R1 and R2 have the aforementioned significance and R3 is a lower alkyl radical. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES369853A ES369853A1 (en) | 1969-07-24 | 1969-07-24 | Procedure for the obtaining of derivatives of the epsilon-amino-caproico acid. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES369853A ES369853A1 (en) | 1969-07-24 | 1969-07-24 | Procedure for the obtaining of derivatives of the epsilon-amino-caproico acid. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES369853A1 true ES369853A1 (en) | 1971-07-16 |
Family
ID=8453493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES369853A Expired ES369853A1 (en) | 1969-07-24 | 1969-07-24 | Procedure for the obtaining of derivatives of the epsilon-amino-caproico acid. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES369853A1 (en) |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000059863A1 (en) * | 1999-04-05 | 2000-10-12 | Emisphere Technologies, Inc. | Disodium salts, monohydrates, and ethanol solvates |
| US6180140B1 (en) | 1994-04-22 | 2001-01-30 | Emisphere Technologies, Inc. | Modified amino acids for drug delivery |
| US6242495B1 (en) | 1997-02-07 | 2001-06-05 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6346242B1 (en) | 1995-03-31 | 2002-02-12 | Emishpere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6348207B1 (en) | 1992-06-15 | 2002-02-19 | Emisiphere Technologies, Inc. | Orally deliverable supramolecular complex |
| US6461643B2 (en) | 1993-04-22 | 2002-10-08 | Emisphere Technologies, Inc. | Oral drug delivery compositions and methods |
| US6663887B2 (en) | 1993-04-22 | 2003-12-16 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US7129274B1 (en) | 1999-11-05 | 2006-10-31 | Emisphere Technologies Inc. | Phenoxy carboxylic acid compounds and compositions for delivering active agents |
| US7151191B2 (en) | 2000-01-13 | 2006-12-19 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US7208483B2 (en) | 1999-01-08 | 2007-04-24 | Emisphere Technologies, Inc. | Polymeric delivery agents and delivery agent compounds |
| US7279597B1 (en) | 1999-11-05 | 2007-10-09 | Emisphere Technologies, Inc. | Phenyl amine carboxylic acid compounds and compositions for delivering active agents |
| US7351741B2 (en) | 2000-06-29 | 2008-04-01 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US7744910B2 (en) | 1998-08-07 | 2010-06-29 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US8686154B2 (en) | 1997-02-07 | 2014-04-01 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
-
1969
- 1969-07-24 ES ES369853A patent/ES369853A1/en not_active Expired
Cited By (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6348207B1 (en) | 1992-06-15 | 2002-02-19 | Emisiphere Technologies, Inc. | Orally deliverable supramolecular complex |
| US6461643B2 (en) | 1993-04-22 | 2002-10-08 | Emisphere Technologies, Inc. | Oral drug delivery compositions and methods |
| US6610329B2 (en) | 1993-04-22 | 2003-08-26 | Emisphere Technologies Inc. | Compositions for the delivery of antigens |
| US6663887B2 (en) | 1993-04-22 | 2003-12-16 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6180140B1 (en) | 1994-04-22 | 2001-01-30 | Emisphere Technologies, Inc. | Modified amino acids for drug delivery |
| US6346242B1 (en) | 1995-03-31 | 2002-02-12 | Emishpere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6242495B1 (en) | 1997-02-07 | 2001-06-05 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6313088B1 (en) | 1997-02-07 | 2001-11-06 | Emisphere Technologies, Inc. | 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents |
| US8686154B2 (en) | 1997-02-07 | 2014-04-01 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US7744910B2 (en) | 1998-08-07 | 2010-06-29 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US7727558B2 (en) | 1999-01-08 | 2010-06-01 | Emisphere Technologies, Inc. | Polymeric delivery agents and delivery agent compounds |
| US7208483B2 (en) | 1999-01-08 | 2007-04-24 | Emisphere Technologies, Inc. | Polymeric delivery agents and delivery agent compounds |
| JP4642435B2 (en) * | 1999-04-05 | 2011-03-02 | ノヴァーティス・アーゲー | Disodium salts, monohydrates, and ethanol solvates for delivering active agents |
| JP2005068161A (en) * | 1999-04-05 | 2005-03-17 | Emisphere Technolgies Inc | Disodium salt, monohydrate, and ethanol solvate for delivering active agent |
| JP2002541132A (en) * | 1999-04-05 | 2002-12-03 | エミスフェアー・テクノロジーズ・インク | Disodium salts, monohydrates, and ethanol solvates for delivering active agents |
| US8003697B2 (en) | 1999-04-05 | 2011-08-23 | Emisphere Technologies, Inc. | Disodium salts, monohydrates, and ethanol solvates for delivering active agents |
| US7384982B2 (en) | 1999-04-05 | 2008-06-10 | Emisphere Technologies, Inc. | Disodium salts, monohydrates, and ethanol solvates for delivering active agents |
| US7659311B2 (en) | 1999-04-05 | 2010-02-09 | Novartis Ag | Disodium salts, monohydrates, and ethanol solvates for delivering active agents |
| WO2000059863A1 (en) * | 1999-04-05 | 2000-10-12 | Emisphere Technologies, Inc. | Disodium salts, monohydrates, and ethanol solvates |
| US7129274B1 (en) | 1999-11-05 | 2006-10-31 | Emisphere Technologies Inc. | Phenoxy carboxylic acid compounds and compositions for delivering active agents |
| US7951971B1 (en) | 1999-11-05 | 2011-05-31 | Emisphere Technologies, Inc. | Phenoxy carboxylic acid compounds and compositions for delivering active agents |
| US8410309B2 (en) | 1999-11-05 | 2013-04-02 | Emisphere Technologies, Inc. | Phenoxy carboxylic acid compounds and compositions for delivering active agents |
| US7279597B1 (en) | 1999-11-05 | 2007-10-09 | Emisphere Technologies, Inc. | Phenyl amine carboxylic acid compounds and compositions for delivering active agents |
| US7151191B2 (en) | 2000-01-13 | 2006-12-19 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US7977506B2 (en) | 2000-01-13 | 2011-07-12 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US7351741B2 (en) | 2000-06-29 | 2008-04-01 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
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