ES2075160T3 - Dispositivo para la administracion transdermica bifasica de drogas. - Google Patents
Dispositivo para la administracion transdermica bifasica de drogas.Info
- Publication number
- ES2075160T3 ES2075160T3 ES90308915T ES90308915T ES2075160T3 ES 2075160 T3 ES2075160 T3 ES 2075160T3 ES 90308915 T ES90308915 T ES 90308915T ES 90308915 T ES90308915 T ES 90308915T ES 2075160 T3 ES2075160 T3 ES 2075160T3
- Authority
- ES
- Spain
- Prior art keywords
- drug
- biphasic
- drugs
- during
- discharge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 title abstract 6
- 229940079593 drug Drugs 0.000 title abstract 6
- 230000002051 biphasic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Surgical Instruments (AREA)
Abstract
SE PROPORCIONA UN SISTEMA DE DESCARGA DE DROGA TRANSDERMAL EN EL QUE LA DESCARGA DE LA DROGA ES EN DOS FASES. LA DROGA SE DESCARGA EN UNA TASA EFECTIVA TERAPEUTICAMENTE DURANTE UNA FASE DE DESCARGA INICIAL, NORMALMENTE DE ENTRE 10 Y 14 HORAS, SEGUIDA DE UNA FASE SECUNDARIA SUBSIGUIENTE DURANTE LA QUE VIRTUALMENTE NO SE DESCARGA NINGUNA DROGA. ESENCIALMENTE TODA LA DROGA INICIALMENTE CARGADA EN EL DISPOSITIVO SE DESCARGA DURANTE LA FASE DE DESCARGA INICIAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/394,096 US5091186A (en) | 1989-08-15 | 1989-08-15 | Biphasic transdermal drug delivery device |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2075160T3 true ES2075160T3 (es) | 1995-10-01 |
Family
ID=23557536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90308915T Expired - Lifetime ES2075160T3 (es) | 1989-08-15 | 1990-08-14 | Dispositivo para la administracion transdermica bifasica de drogas. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5091186A (es) |
EP (1) | EP0413553B1 (es) |
JP (1) | JPH04507256A (es) |
AT (1) | ATE124276T1 (es) |
AU (1) | AU648990B2 (es) |
CA (1) | CA2064765C (es) |
DE (1) | DE69020458T2 (es) |
ES (1) | ES2075160T3 (es) |
FI (1) | FI920601A0 (es) |
IE (1) | IE67774B1 (es) |
NZ (1) | NZ234881A (es) |
PT (1) | PT95014A (es) |
WO (1) | WO1991002506A1 (es) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5358715A (en) * | 1992-09-02 | 1994-10-25 | Cygnus Therapeutic Systems | Enhancement of transdermal drug delivery using monoalkyl phosphates and other absorption promoters |
US5308625A (en) * | 1992-09-02 | 1994-05-03 | Cygnus Therapeutic Systems | Enhancement of transdermal drug delivery using monoalkyl phosphates and other absorption promoters |
US5613958A (en) * | 1993-05-12 | 1997-03-25 | Pp Holdings Inc. | Transdermal delivery systems for the modulated administration of drugs |
WO1995001766A1 (en) * | 1993-07-09 | 1995-01-19 | Cygnus Therapeutic Systems | Method and device for providing nicotine replacement therapy transdermally/transbuccally |
DE4445003A1 (de) * | 1994-12-16 | 1996-06-20 | Fhw Feucht Hygiene Werk Gmbh | Desinfizierendes Mittel |
CA2223588C (en) | 1995-06-07 | 2004-01-06 | Noven Pharmaceuticals, Inc. | Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures |
FR2735024B1 (fr) * | 1995-06-08 | 1997-11-28 | Sanofi Sa | Dispositif d'administration cutanee d'un produit medicamenteux ou cosmetique. |
US5807570A (en) * | 1995-09-29 | 1998-09-15 | Cygnus, Inc. | Transdermal administration of ropinirole and analogs thereof |
US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
JP4477152B2 (ja) * | 1997-05-16 | 2010-06-09 | 株式会社共和 | ストーマ用又は瘡傷用の皮膚保護材 |
IT1294748B1 (it) | 1997-09-17 | 1999-04-12 | Permatec Tech Ag | Formulazione per un dispositivo transdermico |
ATE241363T1 (de) * | 1998-02-11 | 2003-06-15 | Rtp Pharma Corp | Ungesättigte fettsäure und steroide enthaltende kombinationspräparate zur behandlung von entzündungen |
DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
US6337328B1 (en) | 1999-03-01 | 2002-01-08 | Sepracor, Inc. | Bupropion metabolites and methods of use |
DE10041478A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
US7018649B2 (en) * | 2000-10-23 | 2006-03-28 | Euro-Celtique, S.A. | Felodipine transdermal device and methods |
ATE460928T1 (de) * | 2000-10-23 | 2010-04-15 | Euro Celtique Sa | Transdermales system zur verabreichung von loratadin und dessen verwendung |
US6682757B1 (en) | 2000-11-16 | 2004-01-27 | Euro-Celtique, S.A. | Titratable dosage transdermal delivery system |
US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
GB0210397D0 (en) * | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
AU2003240301B2 (en) | 2002-06-25 | 2008-02-14 | Acrux Dds Pty Ltd | Transdermal delivery rate control using amorphous pharmaceutical compositions |
DE10234673B4 (de) * | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
US20040029959A1 (en) * | 2002-08-08 | 2004-02-12 | John Devane | Isosorbide mononitrate compositions and methods of their use |
SI1426049T1 (en) * | 2002-12-02 | 2005-08-31 | Sanol Arznei Schwarz Gmbh | Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease |
DE10261696A1 (de) * | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
AU2005244096B2 (en) | 2004-05-07 | 2011-03-17 | Algenis Spa | Transdermal administration of phycotoxins |
WO2006135785A2 (en) * | 2005-06-10 | 2006-12-21 | Medical College Of Georgia Research Institute | Compositions and methods for treating immune disorders |
US9446017B2 (en) | 2005-08-11 | 2016-09-20 | Augusta University Research Institute, Inc. | Compositions and methods for treating herpes simplex virus |
US7740879B2 (en) * | 2006-01-17 | 2010-06-22 | Harrogate Holdings | Abuse resistant transdermal drug delivery patch |
US9114133B2 (en) | 2006-08-25 | 2015-08-25 | U.S. Dept. Of Veterans Affairs | Method of improving diastolic dysfunction |
CA2695634C (en) | 2007-08-06 | 2018-01-23 | Serenity Pharmaceuticals Corporation | Methods and devices for desmopressin drug delivery |
HUE030409T2 (en) * | 2008-05-21 | 2017-05-29 | Ferring Bv | Orodispersible desmopressin preparation to increase the length of the initial period of sleep disturbed by nocturia |
US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
WO2011014775A1 (en) | 2009-07-31 | 2011-02-03 | The Brigham And Women's Hospital, Inc. | Modulation of sgk1 expression in th17 cells to modulate th17-mediated immune responses |
WO2011127232A2 (en) | 2010-04-08 | 2011-10-13 | Emory University | Substituted androst-4-ene diones |
CA2830069C (en) | 2011-03-20 | 2019-11-12 | The University Of British Columbia | Therapeutic agent for emphysema and copd |
US9480696B2 (en) | 2011-05-04 | 2016-11-01 | Trustees Of Boston University | Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria |
US20140227293A1 (en) | 2011-06-30 | 2014-08-14 | Trustees Of Boston University | Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1) |
EP2543370A1 (en) | 2011-07-06 | 2013-01-09 | Georgia Health Sciences University Research Institute, Inc. | Compositions and Methods for Treating Herpes Simplex Virus |
US9243037B2 (en) | 2011-11-10 | 2016-01-26 | Trustees Of Boston College | Gramicidin a mutants that function as antibiotics with improved solubility and reduced toxicity |
EP2938391B1 (en) | 2012-12-28 | 2022-07-27 | Teikoku Seiyaku Co., Ltd. | Extended buprenorphine transdermal delivery compositions |
WO2014130922A1 (en) | 2013-02-25 | 2014-08-28 | Trustees Of Boston University | Compositions and methods for treating fungal infections |
EP3036226B1 (en) | 2013-08-22 | 2020-01-08 | The General Hospital Corporation | Inhibitors of human 12/15-lipoxygenase |
US11382883B2 (en) | 2013-08-29 | 2022-07-12 | Trustees Of Boston University | Intermediate metabolism products to potentiate aminoglycoside antibiotics in bacterial infections |
WO2016196664A1 (en) | 2015-06-01 | 2016-12-08 | Cedars-Sinai Medical Center | Methods and use of compounds that bind to rela of nf-kb |
WO2017017631A2 (en) | 2015-07-28 | 2017-02-02 | Vyome Biosciences Pvt. Ltd. | Antibacterial therapeutics and prophylactics |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3854480A (en) * | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
US3797494A (en) * | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
US3742951A (en) * | 1971-08-09 | 1973-07-03 | Alza Corp | Bandage for controlled release of vasodilators |
US3996934A (en) * | 1971-08-09 | 1976-12-14 | Alza Corporation | Medical bandage |
US3921636A (en) * | 1973-01-15 | 1975-11-25 | Alza Corp | Novel drug delivery device |
US4036227A (en) * | 1973-04-25 | 1977-07-19 | Alza Corporation | Osmotic releasing device having a plurality of release rate patterns |
US3923939A (en) * | 1974-06-07 | 1975-12-02 | Alza Corp | Process for improving release kinetics of a monolithic drug delivery device |
CA1163561A (en) * | 1979-11-06 | 1984-03-13 | Cyril Boroda | Preparation containing nitroglycerine and optionally other medicaments and preparation thereof |
US4286592A (en) * | 1980-02-04 | 1981-09-01 | Alza Corporation | Therapeutic system for administering drugs to the skin |
US4336243A (en) * | 1980-08-11 | 1982-06-22 | G. D. Searle & Co. | Transdermal nitroglycerin pad |
IL61721A (en) * | 1980-12-16 | 1984-03-30 | Blank Izhak | Nitroglycerin preparations |
US4661105A (en) * | 1981-06-29 | 1987-04-28 | Alza Corporation | Medical bandage for administering vasodilator drug |
US4725272A (en) * | 1981-06-29 | 1988-02-16 | Alza Corporation | Novel bandage for administering beneficial drug |
US4650484A (en) * | 1983-02-03 | 1987-03-17 | Alza Corporation | Method for treating ischemic conditions |
US4704119A (en) * | 1983-02-03 | 1987-11-03 | Alza Corporation | Method comprising transdermal and buccal treatment of angina |
DE3305935C2 (de) * | 1983-02-21 | 1985-05-30 | Medice Chem.-Pharm. Fabrik Pütter GmbH & Co KG, 5860 Iserlohn | Kaliumneutrales Saluretikum mit antihypertensiver Wirkung |
US4559222A (en) * | 1983-05-04 | 1985-12-17 | Alza Corporation | Matrix composition for transdermal therapeutic system |
US4605548A (en) * | 1983-05-31 | 1986-08-12 | Nitto Electric Industrial Co., Ltd. | Drug administration material |
US4601893A (en) * | 1984-02-08 | 1986-07-22 | Pfizer Inc. | Laminate device for controlled and prolonged release of substances to an ambient environment and method of use |
US4786282A (en) * | 1985-02-26 | 1988-11-22 | Adria Laboratories | Bandage for the topical administration of controlled amounts of nitroglycerin ointment |
US4751087A (en) * | 1985-04-19 | 1988-06-14 | Riker Laboratories, Inc. | Transdermal nitroglycerin delivery system |
US4681584A (en) * | 1985-05-03 | 1987-07-21 | Alza Corporation | Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes |
US4615699A (en) * | 1985-05-03 | 1986-10-07 | Alza Corporation | Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes |
DE3518707A1 (de) * | 1985-05-24 | 1986-11-27 | Beiersdorf Ag, 2000 Hamburg | Nitro-pflaster |
US4655766A (en) * | 1985-08-01 | 1987-04-07 | Alza Corporation | Fluid imbibing pump with self-regulating skin patch |
US4717568A (en) * | 1985-08-09 | 1988-01-05 | Alza Corporation | Laminar arrangement for increasing delivery of beneficial agent from dispenser |
US4698062A (en) * | 1985-10-30 | 1987-10-06 | Alza Corporation | Medical device for pulsatile transdermal delivery of biologically active agents |
US4666441A (en) * | 1985-12-17 | 1987-05-19 | Ciba-Geigy Corporation | Multicompartmentalized transdermal patches |
US4723957A (en) * | 1986-02-07 | 1988-02-09 | Alza Corp. | System for delivering drug with enhanced bioacceptability |
US4830690A (en) * | 1986-05-05 | 1989-05-16 | Diane Cooper | Method for making an art work from colored adhesives |
DE3617158C2 (de) * | 1986-05-22 | 1994-10-06 | Lohmann Therapie Syst Lts | Transdermales Arzneimittel |
US4784857A (en) * | 1986-06-03 | 1988-11-15 | Smith And Nephew Associated Companies Plc | Drug delivery device, its preparation and use |
ES2028074T3 (es) * | 1986-06-13 | 1992-07-01 | Alza Corporation | Activacion por humedad de un sistema de suministro transdermico de farmacos. |
US4906463A (en) * | 1986-12-22 | 1990-03-06 | Cygnus Research Corporation | Transdermal drug-delivery composition |
US4746515A (en) * | 1987-02-26 | 1988-05-24 | Alza Corporation | Skin permeation enhancer compositions using glycerol monolaurate |
US4906643A (en) * | 1987-07-17 | 1990-03-06 | Janssen Pharmaceutica N.V. | Substituted N-(3-hydroxy-4-piperidinyl)benzamides as gastrointestinal agents |
US4898920A (en) * | 1987-10-15 | 1990-02-06 | Dow Corning Corporation | Adhesive compositions, controlled release compositions and transdermal delivery device |
JP2639416B2 (ja) * | 1988-04-23 | 1997-08-13 | 財団法人化学及血清療法研究所 | 真珠生産用二枚貝の血球活性化製剤および該製剤を用いる真珠の生産方法 |
-
1989
- 1989-08-15 US US07/394,096 patent/US5091186A/en not_active Expired - Lifetime
-
1990
- 1990-08-13 NZ NZ234881A patent/NZ234881A/en unknown
- 1990-08-14 EP EP90308915A patent/EP0413553B1/en not_active Expired - Lifetime
- 1990-08-14 AU AU62962/90A patent/AU648990B2/en not_active Ceased
- 1990-08-14 CA CA002064765A patent/CA2064765C/en not_active Expired - Fee Related
- 1990-08-14 ES ES90308915T patent/ES2075160T3/es not_active Expired - Lifetime
- 1990-08-14 DE DE69020458T patent/DE69020458T2/de not_active Expired - Fee Related
- 1990-08-14 WO PCT/US1990/004576 patent/WO1991002506A1/en active Application Filing
- 1990-08-14 JP JP2512250A patent/JPH04507256A/ja active Pending
- 1990-08-14 AT AT90308915T patent/ATE124276T1/de active
- 1990-08-14 IE IE294790A patent/IE67774B1/en not_active IP Right Cessation
- 1990-08-16 PT PT199095014A patent/PT95014A/pt not_active Application Discontinuation
-
1992
- 1992-02-12 FI FI920601A patent/FI920601A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU648990B2 (en) | 1994-05-12 |
DE69020458T2 (de) | 1995-11-09 |
JPH04507256A (ja) | 1992-12-17 |
EP0413553A1 (en) | 1991-02-20 |
IE67774B1 (en) | 1996-04-17 |
EP0413553B1 (en) | 1995-06-28 |
US5091186A (en) | 1992-02-25 |
WO1991002506A1 (en) | 1991-03-07 |
PT95014A (pt) | 1991-04-18 |
DE69020458D1 (de) | 1995-08-03 |
CA2064765A1 (en) | 1991-02-16 |
NZ234881A (en) | 1992-02-25 |
ATE124276T1 (de) | 1995-07-15 |
AU6296290A (en) | 1991-04-03 |
FI920601A0 (fi) | 1992-02-12 |
IE902947A1 (en) | 1991-04-10 |
CA2064765C (en) | 1995-09-12 |
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Legal Events
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FG2A | Definitive protection |
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