EE05241B1 - Distamtsiini a-halogenoakrlolderivaadi kasutamine - Google Patents

Distamtsiini a-halogenoakrlolderivaadi kasutamine

Info

Publication number
EE05241B1
EE05241B1 EEP200300129A EEP200300129A EE05241B1 EE 05241 B1 EE05241 B1 EE 05241B1 EE P200300129 A EEP200300129 A EE P200300129A EE P200300129 A EEP200300129 A EE P200300129A EE 05241 B1 EE05241 B1 EE 05241B1
Authority
EE
Estonia
Prior art keywords
derivative
halogenoacryl
distamycin
administration
tumors
Prior art date
Application number
EEP200300129A
Other languages
English (en)
Inventor
Fowst Camilla
Vreeland Franzanne
Cristina Rosa Geroni Maria
Original Assignee
Pharmacia Italia S.P.A.
Pharmacia & Upjohn Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia S.P.A., Pharmacia & Upjohn Company filed Critical Pharmacia Italia S.P.A.
Publication of EE200300129A publication Critical patent/EE200300129A/et
Publication of EE05241B1 publication Critical patent/EE05241B1/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EEP200300129A 2000-10-02 2001-09-21 Distamtsiini a-halogenoakrlolderivaadi kasutamine EE05241B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/676,770 US6576612B1 (en) 2000-10-02 2000-10-02 Antitumor therapy comprising distamycin derivatives
PCT/EP2001/010988 WO2002028389A1 (en) 2000-10-02 2001-09-21 Antitumor therapy comprising distamycin derivatives

Publications (2)

Publication Number Publication Date
EE200300129A EE200300129A (et) 2003-06-16
EE05241B1 true EE05241B1 (et) 2009-12-15

Family

ID=24715919

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300129A EE05241B1 (et) 2000-10-02 2001-09-21 Distamtsiini a-halogenoakrlolderivaadi kasutamine

Country Status (24)

Country Link
US (2) US6576612B1 (et)
EP (1) EP1345604B1 (et)
JP (1) JP2004510734A (et)
KR (1) KR100827560B1 (et)
CN (1) CN1468099A (et)
AT (1) ATE339202T1 (et)
AU (2) AU2162202A (et)
BR (1) BR0114389A (et)
CA (1) CA2424116A1 (et)
CZ (1) CZ299686B6 (et)
DE (1) DE60123117T2 (et)
EA (1) EA006295B1 (et)
EE (1) EE05241B1 (et)
ES (1) ES2267841T3 (et)
HU (1) HUP0301247A2 (et)
IL (1) IL154755A0 (et)
MX (1) MXPA03002824A (et)
MY (1) MY134690A (et)
NO (1) NO20031410L (et)
PE (1) PE20020487A1 (et)
PL (1) PL363926A1 (et)
SK (1) SK5032003A3 (et)
WO (1) WO2002028389A1 (et)
ZA (1) ZA200303405B (et)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015446D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites
GB0015447D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
US6576612B1 (en) * 2000-10-02 2003-06-10 Pharmacia Italia S.P.A. Antitumor therapy comprising distamycin derivatives
US20070249651A1 (en) * 2001-06-20 2007-10-25 Nerviano Medical Sciences S.R.I. Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors
US6969592B2 (en) * 2001-09-26 2005-11-29 Pharmacia Italia S.P.A. Method for predicting the sensitivity to chemotherapy
BR0308976A (pt) * 2002-04-02 2005-01-11 Pharmacia Italia Spa Terapia combinada contra tumores compreendendo derivados de acriloil distamicina substituìda e radioterapia
WO2004035045A1 (en) * 2002-10-16 2004-04-29 Pharmacia Italia S.P.A. Use of substituted acrylolyl distamycin derivatives in combination with demethylating agents, in the treatment of cancer
ES2369705T3 (es) * 2005-12-27 2011-12-05 Universidad Del Pais Vasco-Euskal Herriko Unibersitatea Nuevos derivados pirrólicos con actividad inhibidora de desacetilasas de histonas.
MD23Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare
MD35Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare
MD36Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare
MD24Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8906709D0 (en) * 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9806689D0 (en) * 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents
GB9928703D0 (en) 1999-12-03 2000-02-02 Pharmacia & Upjohn Spa Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents
US6576612B1 (en) * 2000-10-02 2003-06-10 Pharmacia Italia S.P.A. Antitumor therapy comprising distamycin derivatives

Also Published As

Publication number Publication date
ZA200303405B (en) 2004-05-03
EE200300129A (et) 2003-06-16
IL154755A0 (en) 2003-10-31
US6576612B1 (en) 2003-06-10
HUP0301247A2 (hu) 2003-09-29
MXPA03002824A (es) 2003-07-14
EP1345604B1 (en) 2006-09-13
SK5032003A3 (en) 2003-08-05
CZ2003909A3 (cs) 2003-08-13
CZ299686B6 (cs) 2008-10-22
EA200300427A1 (ru) 2003-10-30
ATE339202T1 (de) 2006-10-15
US20040006023A1 (en) 2004-01-08
NO20031410D0 (no) 2003-03-27
KR20030096222A (ko) 2003-12-24
KR100827560B1 (ko) 2008-05-07
PL363926A1 (en) 2004-11-29
CA2424116A1 (en) 2002-04-11
JP2004510734A (ja) 2004-04-08
EA006295B1 (ru) 2005-10-27
WO2002028389A1 (en) 2002-04-11
NO20031410L (no) 2003-03-27
CN1468099A (zh) 2004-01-14
DE60123117T2 (de) 2007-02-08
AU2162202A (en) 2002-04-15
MY134690A (en) 2007-12-31
ES2267841T3 (es) 2007-03-16
AU2002221622B2 (en) 2007-05-17
EP1345604A1 (en) 2003-09-24
BR0114389A (pt) 2004-02-03
US7399748B2 (en) 2008-07-15
DE60123117D1 (de) 2006-10-26
PE20020487A1 (es) 2002-05-23

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Legal Events

Date Code Title Description
HK1A Erratum in gazette
GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20110921