ECSP982780A - NEW PHARMACEUTICAL PRODUCT PROCESS FOR ITS PREPARATION AND USE IN MEDICINE - Google Patents

NEW PHARMACEUTICAL PRODUCT PROCESS FOR ITS PREPARATION AND USE IN MEDICINE

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Publication number
ECSP982780A
ECSP982780A ECSP982780A ECSP982780A EC SP982780 A ECSP982780 A EC SP982780A EC SP982780 A ECSP982780 A EC SP982780A EC SP982780 A ECSP982780 A EC SP982780A
Authority
EC
Ecuador
Prior art keywords
provides
compound
medicine
preparation
presented
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Michael John Sasse
Paul David James Blackler
David C Lee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP982780 priority Critical patent/ECSP982780A/en
Publication of ECSP982780A publication Critical patent/ECSP982780A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un hidrato de la sal de ácido maléico de 5-(4-(2-(N-metil-N-(2-piridil)amino etoxi)bencil) tiazolidina-2,4-diona caracterizado porque: (i) comprende agua en el intervalo de 0,4 a 2,5% p/p; y (ii) proporciona un espectro infrarrojo que contiene picos a 1749, 1703, 1645, 1623, 1365, y 736 cm-1 y/o (iii) proporciona un modelo de difracción de rayos X en polvo (XRPD) sustancialmente como se presenta en la figura II y/o proporciona un espectro Ramán que contiene picos a 3106, 3069, 3002, 2961, 1750, 1718, 1684, 1385, 1335, 1229, 1078, 917, 428, y 349 cm-1 y/o (iv) (v) proporciona un espectro de resonancia magnética nuclear en estado sólido que contiene desplazamiento químicos sustancialmente como los presentados en la tabla I; un proceso para la preparación de tal compuesto, una composición farmacéutica que contiene tal compuesto y el uso de tal compuesto o composición en medicina.A hydrate of the maleic acid salt of 5- (4- (2- (N-methyl-N- (2-pyridyl) amino ethoxy) benzyl) thiazolidine-2,4-dione characterized in that: (i) comprises water in the range of 0.4 to 2.5% w / w; and (ii) provides an infrared spectrum containing peaks at 1749, 1703, 1645, 1623, 1365, and 736 cm-1 and / or (iii) provides a X-ray powder diffraction pattern (XRPD) substantially as presented in Figure II and / or provides a peak-containing Raman spectrum at 3106, 3069, 3002, 2961, 1750, 1718, 1684, 1385, 1335, 1229, 1078, 917, 428, and 349 cm-1 and / or (iv) (v) provides a solid state nuclear magnetic resonance spectrum containing chemical shifts substantially as presented in Table I; a process for the preparation of such compound, a pharmaceutical composition containing such compound and the use of such compound or composition in medicine.

ECSP982780 1998-12-15 1998-12-15 NEW PHARMACEUTICAL PRODUCT PROCESS FOR ITS PREPARATION AND USE IN MEDICINE ECSP982780A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP982780 ECSP982780A (en) 1998-12-15 1998-12-15 NEW PHARMACEUTICAL PRODUCT PROCESS FOR ITS PREPARATION AND USE IN MEDICINE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP982780 ECSP982780A (en) 1998-12-15 1998-12-15 NEW PHARMACEUTICAL PRODUCT PROCESS FOR ITS PREPARATION AND USE IN MEDICINE

Publications (1)

Publication Number Publication Date
ECSP982780A true ECSP982780A (en) 1999-05-17

Family

ID=42043699

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP982780 ECSP982780A (en) 1998-12-15 1998-12-15 NEW PHARMACEUTICAL PRODUCT PROCESS FOR ITS PREPARATION AND USE IN MEDICINE

Country Status (1)

Country Link
EC (1) ECSP982780A (en)

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