ECSP13012467A - Uso de aglutinantes para fabricar formulaciones estables al almacenamiento - Google Patents

Uso de aglutinantes para fabricar formulaciones estables al almacenamiento

Info

Publication number
ECSP13012467A
ECSP13012467A ECSP13012467A ECSP13012467A EC SP13012467 A ECSP13012467 A EC SP13012467A EC SP13012467 A ECSP13012467 A EC SP13012467A EC SP13012467 A ECSP13012467 A EC SP13012467A
Authority
EC
Ecuador
Prior art keywords
storage
manufacture
binders
formulations
pharmaceutically acceptable
Prior art date
Application number
Other languages
English (en)
Inventor
Derek Allan Prater
Christof Spitzley
Gerhard Josef Heun
Alexander Schütz
Udo Hahn
Christian Leuner
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43382375&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP13012467(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of ECSP13012467A publication Critical patent/ECSP13012467A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a formas de dosificación farmacéuticas, de liberación prolongada, estables al almacenamiento, que comprenden oxicodona o una sal farmacéuticamente aceptable de la misma y naloxona o una sal farmacéuticamente aceptable de la misma, a la fabricación de las mismas así como a su uso para la administración a seres humanos.
ECSP13012467 2010-08-13 2013-02-28 Uso de aglutinantes para fabricar formulaciones estables al almacenamiento ECSP13012467A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37334410P 2010-08-13 2010-08-13
EP10172759 2010-08-13

Publications (1)

Publication Number Publication Date
ECSP13012467A true ECSP13012467A (es) 2013-03-28

Family

ID=43382375

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP13012467 ECSP13012467A (es) 2010-08-13 2013-02-28 Uso de aglutinantes para fabricar formulaciones estables al almacenamiento

Country Status (28)

Country Link
US (2) US20130245054A1 (es)
EP (2) EP2603205B1 (es)
JP (1) JP6007176B2 (es)
KR (1) KR101518143B1 (es)
CN (1) CN103118668B (es)
AR (1) AR082688A1 (es)
AU (1) AU2011288413B2 (es)
BR (1) BR112013003150B1 (es)
CA (1) CA2805974C (es)
CH (1) CH705678B1 (es)
CL (1) CL2013000444A1 (es)
CO (1) CO6680640A2 (es)
DE (1) DE112011102708T5 (es)
DK (1) DK178702B1 (es)
EC (1) ECSP13012467A (es)
ES (1) ES2409069B2 (es)
GB (1) GB2495676B (es)
MX (1) MX355644B (es)
MY (1) MY165149A (es)
NO (1) NO20130366A1 (es)
NZ (1) NZ606123A (es)
PE (1) PE20131101A1 (es)
RU (1) RU2572695C2 (es)
SE (1) SE537698C2 (es)
SG (1) SG187678A1 (es)
SI (1) SI2603205T1 (es)
TW (1) TWI469781B (es)
WO (1) WO2012020097A2 (es)

Families Citing this family (20)

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Publication number Priority date Publication date Assignee Title
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
EP1041987B1 (en) 1997-12-22 2006-04-19 Euro-Celtique S.A. Pharmaceutical oral dosage form comprising a combination of an opioid agonist and naltrexone
JP4522652B2 (ja) 2001-05-11 2010-08-11 エンドー ファーマシューティカルズ， インコーポレイティド 乱用防止制御放出オピオイド投薬形態
ES2608006T3 (es) 2002-04-05 2017-04-05 Euro-Celtique S.A. Preparación farmacéutica que contiene oxicodona y naloxona
EP1702558A1 (en) 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
RU2522212C2 (ru) 2009-03-10 2014-07-10 Еуро-Селтик С.А. Фармацевтические композиции с мгновенным высвобождением, содержащие оксикодон и налоксон
CN103002881B (zh) 2010-05-10 2015-09-02 欧洲凯尔特公司 载有活性剂的颗粒与额外活性剂的组合
ES2642788T3 (es) 2010-05-10 2017-11-20 Euro-Celtique S.A. Fabricación de gránulos sin principio activo y de comprimidos que comprenden los mismos
US20140271893A1 (en) * 2013-03-15 2014-09-18 Mcneil-Ppc, Inc. Coated phenylephrine particles and use thereof in pharmaceutical formulations
CN105517551A (zh) 2013-07-23 2016-04-20 欧洲凯尔特公司 用于在患有疼痛和导致肠生态失调和/或提高肠细菌移位风险之疾病的患者中治疗疼痛的羟考酮与纳洛酮的组合
JP6539274B2 (ja) 2013-08-12 2019-07-03 ファーマシューティカル マニュファクチュアリング リサーチ サービシズ，インコーポレーテッド 押出成形された即放性乱用抑止性丸剤
EP3068397A1 (en) 2013-11-13 2016-09-21 Euro-Celtique S.A. Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
DK3169315T3 (da) 2014-07-17 2020-08-10 Pharmaceutical Manufacturing Res Services In Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse
US20160106737A1 (en) 2014-10-20 2016-04-21 Pharmaceutical Manufacturing Research Services, Inc. Extended Release Abuse Deterrent Liquid Fill Dosage Form
EP3229785A2 (de) * 2014-12-08 2017-10-18 Develco Pharma Schweiz AG Naloxon-monopräparat und mehrschichttablette
WO2018055199A1 (en) 2016-09-26 2018-03-29 Euro-Celtique S.A. Methods of treatment comprising administering a high daily dose of oxycodone and naloxone in a 2:1 weight ratio
WO2018189311A1 (en) * 2017-04-13 2018-10-18 Jean Paul Remon Xanthohumol-based compositions
CN111686094A (zh) * 2020-07-13 2020-09-22 云南民族大学 一种脂肪醇类化合物在制备通便药物中的应用

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EP0164669B1 (de) 1984-06-13 1991-01-23 Röhm Gmbh Verfahren zum Überziehen von Arzneiformen
EP1442745A1 (en) * 1993-10-07 2004-08-04 Euro-Celtique Orally administrable opioid formulations having extended duration of effect
US6245357B1 (en) * 1998-03-06 2001-06-12 Alza Corporation Extended release dosage form
JP4848558B2 (ja) * 2001-05-08 2011-12-28 トーアエイヨー株式会社 塩酸メトホルミン含有速放性錠剤
US7943173B2 (en) * 2001-07-18 2011-05-17 Purdue Pharma L.P. Pharmaceutical combinations of oxycodone and naloxone
US7332182B2 (en) * 2001-08-06 2008-02-19 Purdue Pharma L.P. Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant
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Also Published As

Publication number Publication date
ES2409069A2 (es) 2013-06-24
EP3505162A1 (en) 2019-07-03
CH705678B1 (de) 2016-03-15
DK178702B1 (en) 2016-11-21
DE112011102708T5 (de) 2013-05-29
ES2409069R1 (es) 2013-08-30
JP2013533303A (ja) 2013-08-22
US20160095853A1 (en) 2016-04-07
ES2409069B2 (es) 2014-07-17
SI2603205T1 (sl) 2019-02-28
KR20130083903A (ko) 2013-07-23
CO6680640A2 (es) 2013-05-31
EP2603205A2 (en) 2013-06-19
WO2012020097A2 (en) 2012-02-16
DK201370075A (en) 2013-02-13
EP2603205B1 (en) 2018-10-03
SE537698C2 (sv) 2015-09-29
JP6007176B2 (ja) 2016-10-12
RU2572695C2 (ru) 2016-01-20
KR101518143B1 (ko) 2015-05-06
BR112013003150B1 (pt) 2022-01-18
NZ606123A (en) 2015-03-27
CL2013000444A1 (es) 2013-08-23
TWI469781B (zh) 2015-01-21
MX2013001757A (es) 2013-05-06
RU2013110820A (ru) 2014-09-20
GB201301916D0 (en) 2013-03-20
WO2012020097A3 (en) 2012-05-03
AU2011288413B2 (en) 2014-05-22
AR082688A1 (es) 2012-12-26
AU2011288413A1 (en) 2013-02-21
CA2805974A1 (en) 2012-02-16
PE20131101A1 (es) 2013-09-23
BR112013003150A2 (pt) 2020-09-08
MX355644B (es) 2018-04-26
NO20130366A1 (no) 2013-04-29
SG187678A1 (en) 2013-03-28
GB2495676A (en) 2013-04-17
CA2805974C (en) 2019-11-26
CN103118668B (zh) 2016-07-06
TW201228662A (en) 2012-07-16
MY165149A (en) 2018-02-28
GB2495676B (en) 2018-08-22
CN103118668A (zh) 2013-05-22
SE1350286A1 (sv) 2013-03-21
US20130245054A1 (en) 2013-09-19

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