ECSP11011534A - 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octano- o heptano-nitrilo como inhibidores de jak - Google Patents

3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octano- o heptano-nitrilo como inhibidores de jak

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Publication number
ECSP11011534A
ECSP11011534A EC2011011534A ECSP11011534A ECSP11011534A EC SP11011534 A ECSP11011534 A EC SP11011534A EC 2011011534 A EC2011011534 A EC 2011011534A EC SP11011534 A ECSP11011534 A EC SP11011534A EC SP11011534 A ECSP11011534 A EC SP11011534A
Authority
EC
Ecuador
Prior art keywords
pirimidin
pirrolo
heptano
pirazol
octano
Prior art date
Application number
EC2011011534A
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English (en)
Inventor
James D Rodgers
Yun-Long Li
Original Assignee
Incyte Corp
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42246359&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP11011534(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of ECSP11011534A publication Critical patent/ECSP11011534A/es

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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

La presente invención se relaciona con los inhibidores de la Janus quinasa (JAK) 3-[4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il]octanonitrilo ó 3-[4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il]heptanonitrilo, así como con sus composiciones y métodos de uso, los cuales son útiles en el tratamiento de enfermedades asociadas a la JAK incluyendo, por ejemplo, trastornos inflamatorios y autoinmunes, trastornos de la piel, cáncer y otras enfermedades.
EC2011011534A 2009-05-22 2011-12-15 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octano- o heptano-nitrilo como inhibidores de jak ECSP11011534A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18058209P 2009-05-22 2009-05-22

Publications (1)

Publication Number Publication Date
ECSP11011534A true ECSP11011534A (es) 2012-01-31

Family

ID=42246359

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2011011534A ECSP11011534A (es) 2009-05-22 2011-12-15 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octano- o heptano-nitrilo como inhibidores de jak

Country Status (35)

Country Link
US (3) US8604043B2 (es)
EP (2) EP2432472B1 (es)
JP (2) JP6172939B2 (es)
KR (1) KR20120030447A (es)
CN (2) CN102458411A (es)
AR (1) AR076920A1 (es)
AU (1) AU2010249443B2 (es)
BR (1) BRPI1012108B8 (es)
CA (1) CA2761954C (es)
CL (1) CL2011002955A1 (es)
CO (1) CO6470876A2 (es)
CR (1) CR20110621A (es)
CY (1) CY1122425T1 (es)
DK (1) DK2432472T3 (es)
EA (1) EA020494B1 (es)
EC (1) ECSP11011534A (es)
ES (1) ES2761300T3 (es)
HR (1) HRP20192203T1 (es)
HU (1) HUE046493T2 (es)
IL (1) IL216359A (es)
LT (1) LT2432472T (es)
ME (1) ME03556B (es)
MX (1) MX2011012262A (es)
MY (1) MY161416A (es)
NZ (1) NZ596374A (es)
PE (1) PE20120371A1 (es)
PL (1) PL2432472T3 (es)
PT (1) PT2432472T (es)
RS (1) RS59632B1 (es)
SG (2) SG176111A1 (es)
SI (1) SI2432472T1 (es)
TW (1) TWI484962B (es)
UA (1) UA106078C2 (es)
WO (1) WO2010135621A1 (es)
ZA (1) ZA201108541B (es)

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