EA200900991A1 - Новые антитела против igf-1r - Google Patents

Новые антитела против igf-1r

Info

Publication number
EA200900991A1
EA200900991A1 EA200900991A EA200900991A EA200900991A1 EA 200900991 A1 EA200900991 A1 EA 200900991A1 EA 200900991 A EA200900991 A EA 200900991A EA 200900991 A EA200900991 A EA 200900991A EA 200900991 A1 EA200900991 A1 EA 200900991A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antibodies against
antibodies
new antibodies
against igf
antigen
Prior art date
Application number
EA200900991A
Other languages
English (en)
Inventor
Майкл Нейл Берден
Джонатан Генри Эллис
Пол Эндрю Хэмблин
Алан Питер Льюис
Радха Шах
Original Assignee
Глаксо Груп Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0702888.9A external-priority patent/GB0702888D0/en
Application filed by Глаксо Груп Лимитед filed Critical Глаксо Груп Лимитед
Publication of EA200900991A1 publication Critical patent/EA200900991A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Настоящее изобретение относится к антителам или их антигенсвязывающим фрагментам, которые специфически связываются с IGF-1R (рецептором инсулиноподобного фактора роста), в частности с hlGF-1R. Также раскрыты препараты антител, содержащие антитела или антигенсвязывающие фрагменты по изобретению. Также в объем настоящего изобретения включены способы продуцирования таких антител или антигенсвязывающих фрагментов и их применения.
EA200900991A 2007-02-14 2008-02-12 Новые антитела против igf-1r EA200900991A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0702888.9A GB0702888D0 (en) 2007-02-14 2007-02-14 Novel Antibodies
US95321007P 2007-08-01 2007-08-01
PCT/EP2008/051655 WO2008098917A2 (en) 2007-02-14 2008-02-12 Novel antibodies against igf-ir

Publications (1)

Publication Number Publication Date
EA200900991A1 true EA200900991A1 (ru) 2010-02-26

Family

ID=42025950

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200900991A EA200900991A1 (ru) 2007-02-14 2008-02-12 Новые антитела против igf-1r

Country Status (5)

Country Link
JP (1) JP2010518140A (ru)
KR (1) KR20090114449A (ru)
EA (1) EA200900991A1 (ru)
MX (1) MX2009008754A (ru)
PE (1) PE20090107A1 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3027824A1 (en) 2010-02-23 2011-09-01 Sanofi Anti-alpha2 integrin antibodies and their uses
UY33578A (es) 2010-08-31 2012-03-30 Sanofi Sa PÉPTIDO O COMPLEJO PEPTÍDICO QUE SE UNE A INTEGRINA a(ALFA) Y MÉTODOS Y USOS QUE IMPLICAN A LOS MISMOS
CN104066845A (zh) * 2011-12-15 2014-09-24 皇家学术促进会/麦吉尔大学 可溶性IGF受体Fc融合蛋白和其用途
CA3002741A1 (en) * 2015-10-23 2017-04-27 Apogenix Ag Single-chain gitr-receptor agonist proteins

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL228041B1 (pl) * 2001-01-05 2018-02-28 Amgen Fremont Inc Przeciwciało przeciwko receptorowi insulinopodobnego czynnika wzrostu I, zawierajaca go kompozycja farmaceutyczna, sposób jego wytwarzania, zastosowania, linia komórkowa, wyizolowana czasteczka kwasu nukleinowego, wektor, komórka gospodarza oraz zwierze transgeniczne.
US7538195B2 (en) * 2002-06-14 2009-05-26 Immunogen Inc. Anti-IGF-I receptor antibody
US8034904B2 (en) * 2002-06-14 2011-10-11 Immunogen Inc. Anti-IGF-I receptor antibody
WO2005016970A2 (en) * 2003-05-01 2005-02-24 Imclone Systems Incorporated Fully human antibodies directed against the human insulin-like growth factor-1 receptor
WO2005058967A2 (en) * 2003-12-16 2005-06-30 Pierre Fabre Medicament Novel anti-insulin/igf-i hybrid receptor or anti-insulin/igf-i hybrid receptor and igf-ir antibodies and uses thereof
FR2873699B1 (fr) * 2004-07-29 2009-08-21 Pierre Fabre Medicament Sa Nouveaux anticorps anti igf ir rt leurs utilisations
WO2007000328A1 (en) * 2005-06-27 2007-01-04 Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa Antibodies that bind to an epitope on insulin-like growth factor 1 receptor and uses thereof
FR2888850B1 (fr) * 2005-07-22 2013-01-11 Pf Medicament Nouveaux anticorps anti-igf-ir et leurs applications

Also Published As

Publication number Publication date
KR20090114449A (ko) 2009-11-03
PE20090107A1 (es) 2009-03-20
MX2009008754A (es) 2009-11-02
JP2010518140A (ja) 2010-05-27

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