EA200501366A1 - MEDICINE - Google Patents

MEDICINE

Info

Publication number
EA200501366A1
EA200501366A1 EA200501366A EA200501366A EA200501366A1 EA 200501366 A1 EA200501366 A1 EA 200501366A1 EA 200501366 A EA200501366 A EA 200501366A EA 200501366 A EA200501366 A EA 200501366A EA 200501366 A1 EA200501366 A1 EA 200501366A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tablets
proposed drug
pyridinecarbonylhydrazinyl
refampicin
pyrazinamide
Prior art date
Application number
EA200501366A
Other languages
Russian (ru)
Other versions
EA013052B1 (en
Inventor
Александр Леонидович Решетов
Ирина Анатольевна Верещагина
Original Assignee
Закрытое Акционерное Общество "Новая Линия"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Закрытое Акционерное Общество "Новая Линия" filed Critical Закрытое Акционерное Общество "Новая Линия"
Publication of EA200501366A1 publication Critical patent/EA200501366A1/en
Publication of EA013052B1 publication Critical patent/EA013052B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Представленное изобретение относится к лекарственному средству, включающему активное вещество и целевые добавки, причем в качестве активного вещества оно содержит (2,4-дигидрокси-6-метил-5-пиримидил)-(4-пиридинкарбонилгидразинил)сульфон формулы (III) или его фармацевтически приемлемые соли и изомеры в эффективном количестве. Кроме того предложенное лекарственное средство дополнительно может содержать по меньшей мере одно противотуберкулезное средство, такое как изониозид, рефампицин, пиразинамид. Предложенное лекарственное средство может быть изготовлено в виде таблеток, комбинированных таблеток, капсул, сиропа и инъекций.The presented invention relates to a medicinal product comprising an active substance and targeted supplements, moreover it contains (2,4-dihydroxy-6-methyl-5-pyrimidyl) - (4-pyridinecarbonylhydrazinyl) sulfone of formula (III) or its pharmaceutically acceptable salts and isomers in an effective amount. In addition, the proposed drug may additionally contain at least one anti-tuberculosis agent, such as isoniazid, refampicin, pyrazinamide. The proposed drug can be manufactured in the form of tablets, combined tablets, capsules, syrup and injections.

EA200501366A 2004-03-26 2004-03-26 Medical preparation EA013052B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU2004/000115 WO2005092344A1 (en) 2004-03-26 2004-03-26 Medicinal preparation

Publications (2)

Publication Number Publication Date
EA200501366A1 true EA200501366A1 (en) 2006-08-25
EA013052B1 EA013052B1 (en) 2010-02-26

Family

ID=35055975

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200501366A EA013052B1 (en) 2004-03-26 2004-03-26 Medical preparation

Country Status (2)

Country Link
EA (1) EA013052B1 (en)
WO (1) WO2005092344A1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2141322C1 (en) * 1997-08-12 1999-11-20 Голощапов Николай Михайлович Immunomodulating agent "izofon" showing antimycobacterial activity, method of its preparing and using
RU2136668C1 (en) * 1997-10-07 1999-09-10 Голощапов Николай Михайлович N,n'-(sulfonyldi-1,4-phenylene)-bis-(n'',n''-dimethylform- -amidine)-1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidine sulfonate stimulating cellular metabolism and showing immunotropic and antibacterial activity
RU2191015C2 (en) * 1999-11-05 2002-10-20 Общество с ограниченной ответственностью "Центр бифункциональных иммуномодуляторов" N-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5h-pyrimidinesulfone)-n′- isonicotinoyl hydrazide disodium salt eliciting antibacterial and immunotropic activity and medicinal agent based on thereof

Also Published As

Publication number Publication date
WO2005092344A1 (en) 2005-10-06
EA013052B1 (en) 2010-02-26

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AZ BY KZ