EA200500864A1 - Новый, содержащий тиотропий порошковый препарат для ингаляции - Google Patents

Новый, содержащий тиотропий порошковый препарат для ингаляции

Info

Publication number
EA200500864A1
EA200500864A1 EA200500864A EA200500864A EA200500864A1 EA 200500864 A1 EA200500864 A1 EA 200500864A1 EA 200500864 A EA200500864 A EA 200500864A EA 200500864 A EA200500864 A EA 200500864A EA 200500864 A1 EA200500864 A1 EA 200500864A1
Authority
EA
Eurasian Patent Office
Prior art keywords
inhalation
tiotropy
new
powder preparation
treatment
Prior art date
Application number
EA200500864A
Other languages
English (en)
Other versions
EA011549B1 (ru
Inventor
Мареке Хартиг
Михаэль Трунк
Михаэль Вальц
Original Assignee
Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32308760&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200500864(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг filed Critical Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг
Publication of EA200500864A1 publication Critical patent/EA200500864A1/ru
Publication of EA011549B1 publication Critical patent/EA011549B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

В заявке описаны содержащие тиотропий порошковые составы для ингаляции, способ их получения, а также их применение для получения лекарственного средства, предназначенного для лечения заболеваний дыхательных путей, прежде всего для лечения хронического обструктивного заболевания легких и астмы.Отчет о международном поиске был опубликован 2004.09.30.
EA200500864A 2002-11-28 2003-11-19 Новый, содержащий тиотропий порошковый препарат для ингаляции EA011549B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10255387A DE10255387A1 (de) 2002-11-28 2002-11-28 Neue Tiotropium-haltige Pulverformulierung für die Inhalation
PCT/EP2003/012911 WO2004047796A2 (de) 2002-11-28 2003-11-19 Neue tiotropium-haltige pulverformulierung für die inhalation

Publications (2)

Publication Number Publication Date
EA200500864A1 true EA200500864A1 (ru) 2006-02-24
EA011549B1 EA011549B1 (ru) 2009-04-28

Family

ID=32308760

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200500864A EA011549B1 (ru) 2002-11-28 2003-11-19 Новый, содержащий тиотропий порошковый препарат для ингаляции

Country Status (34)

Country Link
EP (1) EP1567135B1 (ru)
JP (1) JP4977321B2 (ru)
KR (1) KR101066805B1 (ru)
CN (1) CN100574751C (ru)
AR (1) AR042242A1 (ru)
AT (1) ATE401861T1 (ru)
AU (1) AU2003294714B2 (ru)
BR (1) BR0316343A (ru)
CA (1) CA2507579C (ru)
CO (1) CO5580736A2 (ru)
CY (1) CY1108420T1 (ru)
DE (2) DE10255387A1 (ru)
DK (1) DK1567135T3 (ru)
EA (1) EA011549B1 (ru)
EC (1) ECSP055821A (ru)
ES (1) ES2310681T3 (ru)
HK (1) HK1085918A1 (ru)
HR (1) HRP20050468A2 (ru)
IL (1) IL168810A (ru)
ME (1) MEP51608A (ru)
MX (1) MXPA05005485A (ru)
MY (1) MY140890A (ru)
NO (1) NO20053090D0 (ru)
PE (1) PE20040848A1 (ru)
PL (1) PL376229A1 (ru)
PT (1) PT1567135E (ru)
RS (1) RS20050400A (ru)
SA (1) SA04240467B1 (ru)
SI (1) SI1567135T1 (ru)
TW (1) TWI332837B (ru)
UA (1) UA81930C2 (ru)
UY (1) UY28096A1 (ru)
WO (1) WO2004047796A2 (ru)
ZA (1) ZA200502859B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102008014025A1 (de) * 2008-03-13 2009-09-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Sieb für einen Inhalator
TR200909788A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Tiotropyum içeren inhalasyona uygun kuru toz formülasyonu
ES2664175T3 (es) * 2010-08-03 2018-04-18 Chiesi Farmaceutici S.P.A. Formulación de polvo seco que comprende un inhibidor de fosfodiesterasa
WO2014074797A1 (en) * 2012-11-09 2014-05-15 Civitas Therapeutics, Inc. Ultra low density pulmonary powders
KR101748796B1 (ko) * 2015-09-30 2017-06-19 한미약품 주식회사 활성성분의 전달량이 향상된 흡입용 캡슐제
KR101728116B1 (ko) * 2015-11-03 2017-04-18 한미약품 주식회사 티오트로피움 또는 이의 약학적으로 허용가능한 염을 함유하는 흡입용 건조분말 조성물
CN111514418B (zh) * 2019-06-12 2022-01-14 中南大学湘雅二医院 一种自吸式经鼻粉末材料给送装置

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242211A (en) * 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
DE4140689B4 (de) * 1991-12-10 2007-11-22 Boehringer Ingelheim Kg Inhalationspulver und Verfahren zu ihrer Herstellung
DE4318455A1 (de) * 1993-06-03 1994-12-08 Boehringer Ingelheim Kg Kapselhalterung
GB9322014D0 (en) * 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
DE4425255A1 (de) * 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
RO122660B1 (ro) * 1998-11-13 2009-11-30 Skypepharma Ag Pulbere inhalabilă uscată
GB9902689D0 (en) * 1999-02-08 1999-03-31 Novartis Ag Organic compounds
UA75375C2 (en) * 2000-10-12 2006-04-17 Boehringer Ingelheim Pharma Method for producing powdery preparations for inhaling
OA12522A (en) * 2000-10-12 2006-05-30 Boehringer Ingelheim Pharma Novel tiotropium-containing inhalation powder.
DE10126924A1 (de) * 2001-06-01 2002-12-05 Boehringer Ingelheim Pharma Inhalationskapseln
DE10141377A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Aufstreuverfahren zur Herstellung von Pulverformulierungen
IL163736A0 (en) * 2002-04-04 2005-12-18 Boehringer Ingelheim Pharma Powder formulations suitable for inhalation
UA80123C2 (en) * 2002-04-09 2007-08-27 Boehringer Ingelheim Pharma Inhalation kit comprising inhalable powder of tiotropium

Also Published As

Publication number Publication date
CY1108420T1 (el) 2014-04-09
SI1567135T1 (sl) 2008-10-31
IL168810A (en) 2015-02-26
CN100574751C (zh) 2009-12-30
EP1567135A2 (de) 2005-08-31
PT1567135E (pt) 2008-09-01
JP2006510622A (ja) 2006-03-30
WO2004047796A2 (de) 2004-06-10
AU2003294714A1 (en) 2004-06-18
UY28096A1 (es) 2004-06-30
AR042242A1 (es) 2005-06-15
SA04240467B1 (ar) 2008-10-15
NO20053090L (no) 2005-06-23
MEP51608A (en) 2011-02-10
MXPA05005485A (es) 2005-07-25
ES2310681T3 (es) 2009-01-16
ZA200502859B (en) 2006-02-22
TWI332837B (en) 2010-11-11
CA2507579A1 (en) 2004-06-10
PL376229A1 (en) 2005-12-27
RS20050400A (en) 2007-04-10
AU2003294714B2 (en) 2009-10-08
MY140890A (en) 2010-01-29
ATE401861T1 (de) 2008-08-15
CA2507579C (en) 2011-07-19
NO20053090D0 (no) 2005-06-23
DE50310208D1 (de) 2008-09-04
WO2004047796A3 (de) 2004-09-30
CN1717225A (zh) 2006-01-04
CO5580736A2 (es) 2005-11-30
JP4977321B2 (ja) 2012-07-18
HK1085918A1 (en) 2006-09-08
EA011549B1 (ru) 2009-04-28
DE10255387A1 (de) 2004-06-09
BR0316343A (pt) 2005-09-27
UA81930C2 (ru) 2008-02-25
ECSP055821A (es) 2005-08-11
KR101066805B1 (ko) 2011-09-22
HRP20050468A2 (en) 2006-07-31
KR20050086887A (ko) 2005-08-30
DK1567135T3 (da) 2008-10-27
TW200500066A (en) 2005-01-01
EP1567135B1 (de) 2008-07-23
PE20040848A1 (es) 2005-01-14

Similar Documents

Publication Publication Date Title
EA200200551A1 (ru) Новые содержащие тиотропий порошки для ингаляции
EA200500902A1 (ru) Порошковые лекарственные средства, содержащие соль тиотропия и ксинафоат салметерола
EA200500715A1 (ru) Новые лекарственные средства для лечения хронического обструктивного заболевания лёгких
EA200300776A1 (ru) Производные фенэтаноламина для лечения респираторных заболеваний
EA200300503A1 (ru) Новые лекарственные композиции на основе солей тиотропия и солей салметерола
SI2042168T1 (sl) Inhalacijska formulacija, ki obsega fenetanolaminske derivate, za zdravljenje respiratornih bolezni
YU71901A (sh) NOVE VRSTE LEKOVITIH KOMPOZICIJA NA BAZI JEDINJENJA KOJA DELUJU ANTIHOLINERGIJSKI I beta-MIMETIKA
MXPA03011515A (es) Nuevas composiciones de medicamentos sobre la base de agentes anticolinergicos, corticoesteroides y agentes betamimeticos.
EA200600854A1 (ru) Новые соли тиотропия, способ их получения, а также содержащие их лекарственные композиции
ATE402141T1 (de) Phenäthanolaminderivate zur behandlung von krankheiten der atemwege
EA200600853A1 (ru) Новый кристаллический ангидрат с антихолинергическим действием
CY1108420T1 (el) Προτοτυπο τιοτροπιουχο κονιωδες σκευασμα για εισπνοη
MXPA03011702A (es) Composicion que comprende un inhibidor de fosodiesterasa 4 y un antagonista de receptor h1 y el uso de los mismos para la elaboracion de un medicamento para el tratamiento de enfermedades respiratorias.
EA200602016A1 (ru) ПОРОШКОВЫЕ КОМПОЗИЦИИ ДЛЯ ИНГАЛЯЦИИ, СОДЕРЖАЩИЕ ЭНАНТИОМЕРНОЧИСТЫЕ β-АГОНИСТЫ
EA200600886A1 (ru) Способ получения солей тиотропия, соли тиотропия, а также содержащие их лекарственные композиции
EA200401303A1 (ru) Лекарственные средства, содержащие стероиды и новое антихолинергическое средство
MXPA04002401A (es) Nuevos medicamentos para inhalacion.
DE60308497D1 (de) Pulverzubereitungen zur inhalation
DE60206391D1 (de) Verwendung von thiazolderivaten zur herstellung eines medikaments zur behandlung von chronischen obstruktiven atemwegserkrankungen
DK1581224T3 (da) Tiotropiumholdig lægemiddelsammensætning til inhalation
EA200301140A1 (ru) Ингибитор pde4 и антихолинергический агент в комбинации для лечения обструктивных болезней дыхательных путей

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG MD TJ TM