EA200400691A1 - Получение чистых стереоизомеров трицикло[5,2,1,02,6]дец-9-ил-ксантогената и содержащие их лекарственные средства - Google Patents

Получение чистых стереоизомеров трицикло[5,2,1,02,6]дец-9-ил-ксантогената и содержащие их лекарственные средства

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Publication number
EA200400691A1
EA200400691A1 EA200400691A EA200400691A EA200400691A1 EA 200400691 A1 EA200400691 A1 EA 200400691A1 EA 200400691 A EA200400691 A EA 200400691A EA 200400691 A EA200400691 A EA 200400691A EA 200400691 A1 EA200400691 A1 EA 200400691A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tricyclo
dec
pure stereoisomers
xantogenat
medicines
Prior art date
Application number
EA200400691A
Other languages
English (en)
Other versions
EA007100B1 (ru
Inventor
Эберхард Амтманн
Original Assignee
Биосфингс Акциенгезелльшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Биосфингс Акциенгезелльшафт filed Critical Биосфингс Акциенгезелльшафт
Publication of EA200400691A1 publication Critical patent/EA200400691A1/ru
Publication of EA007100B1 publication Critical patent/EA007100B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
    • C07C329/12—Dithiocarbonic acids; Derivatives thereof
    • C07C329/14—Esters of dithiocarbonic acids
    • C07C329/18—Esters of dithiocarbonic acids having sulfur atoms of dithiocarbonic groups bound to carbon atoms of rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Изобретение относится к фармацевтическим композициям, содержащим экзо/экзо-трицикло[5,2,1,0]дец-9-илксантогенат, лекарственным средствам для лечения генитального герпеса, лабиального герпеса, СПИДа, опухолей или аутоиммунных заболеваний, которые содержат экзо/экзо-трицикло[5,2,1,0]дец-9-илксантогенат в качестве биологически активного вещества, а также способам получения чистых стереоизомеров трицикло [5,2,1,0]декан-9-ола и трицикло [5,2,1,0]дец-9-илксантогената.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200400691A 2001-11-17 2002-11-02 Экзо/экзо-трицикло[5,2,1,0дец-9-ил-ксантогенат, способ его получения и применение в качестве противовирусного средства EA007100B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10156617A DE10156617A1 (de) 2001-11-17 2001-11-17 Herstellung reiner Stereoisomere von Tricyclo[5.2.1.0··2··.··6··]-dec-9-yl-xanthogenat und Arzneimittel daraus
PCT/EP2002/012242 WO2003041702A1 (de) 2001-11-17 2002-11-02 Herstellung reiner stereoisomere von tricyclo[5.2.1.02.6]-dec-9-yl xanthogenat und arzneimittel daraus

Publications (2)

Publication Number Publication Date
EA200400691A1 true EA200400691A1 (ru) 2004-10-28
EA007100B1 EA007100B1 (ru) 2006-06-30

Family

ID=7706153

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200400691A EA007100B1 (ru) 2001-11-17 2002-11-02 Экзо/экзо-трицикло[5,2,1,0дец-9-ил-ксантогенат, способ его получения и применение в качестве противовирусного средства

Country Status (9)

Country Link
US (1) US7915237B2 (ru)
EP (1) EP1443921B1 (ru)
JP (1) JP4046691B2 (ru)
CN (1) CN100367948C (ru)
AT (1) ATE293445T1 (ru)
DE (2) DE10156617A1 (ru)
EA (1) EA007100B1 (ru)
ES (1) ES2242100T3 (ru)
WO (1) WO2003041702A1 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10343365A1 (de) * 2003-09-17 2005-04-14 Biosphings Ag Pharmazeutische Formulierungen von Xanthogenaten und Hemmstoffen der viralen Nukleinsäurereplikation
JP5133568B2 (ja) * 2007-01-11 2013-01-30 株式会社ディスコ レーザー加工装置
US20100240746A1 (en) * 2007-07-03 2010-09-23 Lumavita Ag Stereoisomers of tricyclodecan-9-yl-xanthogenate
DE102009030291A1 (de) 2009-06-24 2011-01-05 Cu Chemie Uetikon Gmbh Enantiomerenreine tricyclische Verbindung und Verfahren zur diastereomerenreinen und enantiomerenreinen Herstellung bicyclischer und tricyclischer Verbindungen
DE102009039587A1 (de) * 2009-09-01 2011-03-10 Bayer Animal Health Gmbh Neue Kombination
CZ33324U1 (cs) 2019-09-06 2019-10-25 Contipro A.S. Hydrogel na bázi zesíťovaného hydroxyfenylového derivátu kyseliny hyaluronové

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK170068B1 (da) 1980-11-26 1995-05-15 Ct Holding Sa Analogifremgangsmåde til fremstilling af xanthater
IT1213453B (it) * 1985-08-02 1989-12-20 Merz & Co Gmbh & Co Composizione farmaceutica.
CN1029399C (zh) * 1992-12-15 1995-08-02 株洲选矿药剂厂 黄原酸盐的生产方法
WO1996014841A1 (en) * 1994-11-14 1996-05-23 Ct-Holding S.A. Antiviral and antitumor pharmaceutical compositions
DE19960204A1 (de) 1999-12-14 2001-06-28 Aventis Pharma Gmbh Substituierte Norlbornylamino-Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
CN1309126A (zh) * 2000-11-09 2001-08-22 中国科学院兰州化学物理研究所 S－(2h－噻吩－2－基)甲基,烷基黄原酸酯
US6756063B2 (en) * 2001-03-29 2004-06-29 Zoltan Laboratories, Llc Methods and compositions for the treatment of human and animal cancers
DE10117728A1 (de) * 2001-04-09 2002-10-17 Biosphings Ag Pharmazeutische Formulierungen für Xanthogenate

Also Published As

Publication number Publication date
US20050085448A1 (en) 2005-04-21
US7915237B2 (en) 2011-03-29
ES2242100T3 (es) 2005-11-01
WO2003041702A1 (de) 2003-05-22
JP2005511618A (ja) 2005-04-28
EA007100B1 (ru) 2006-06-30
CN100367948C (zh) 2008-02-13
JP4046691B2 (ja) 2008-02-13
DE50202865D1 (de) 2005-05-25
EP1443921B1 (de) 2005-04-20
ATE293445T1 (de) 2005-05-15
DE10156617A1 (de) 2003-05-28
CN1589142A (zh) 2005-03-02
EP1443921A1 (de) 2004-08-11

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