EA200100140A1 - Терапевтическая композиция на основе флавоноидов для применения в лечении опухолей цитотоксическими агентами - Google Patents
Терапевтическая композиция на основе флавоноидов для применения в лечении опухолей цитотоксическими агентамиInfo
- Publication number
- EA200100140A1 EA200100140A1 EA200100140A EA200100140A EA200100140A1 EA 200100140 A1 EA200100140 A1 EA 200100140A1 EA 200100140 A EA200100140 A EA 200100140A EA 200100140 A EA200100140 A EA 200100140A EA 200100140 A1 EA200100140 A1 EA 200100140A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- tumors
- treatment
- cytotoxic agents
- flavonoids
- application
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
Изобретение касается композиции, обладающей активностью в отношении пролиферации клоногенных клеток в опухолях и включающей терапевтически эффективное количество флавоноида, в частности соединения, выбранного из соединений формулы (I)в которой R, R, Rи R, Rи Rтаковы, как они определены в п.2. формулы изобретения. Указанная композиция предназначена для применения в лечении опухолей цитотоксическими агентами.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9809058A FR2781153B1 (fr) | 1998-07-15 | 1998-07-15 | Composition therapeutique a base de flavonoides destinee a etre utilisee dans le traitement des tumeurs par des agents cytotoxiques |
PCT/FR1999/001714 WO2000003706A1 (fr) | 1998-07-15 | 1999-07-13 | Composition therapeutique a base de flavonoïdes destinee a etre utilisee dans le traitement des tumeurs par des agents cytotoxiques |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200100140A1 true EA200100140A1 (ru) | 2001-06-25 |
Family
ID=9528648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200100140A EA200100140A1 (ru) | 1998-07-15 | 1999-07-13 | Терапевтическая композиция на основе флавоноидов для применения в лечении опухолей цитотоксическими агентами |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1096930A1 (ru) |
JP (1) | JP2002520356A (ru) |
KR (1) | KR20020003349A (ru) |
CN (1) | CN1139384C (ru) |
AU (1) | AU4789099A (ru) |
BR (1) | BR9912816A (ru) |
CA (1) | CA2337179A1 (ru) |
EA (1) | EA200100140A1 (ru) |
FR (1) | FR2781153B1 (ru) |
IL (1) | IL140588A0 (ru) |
WO (1) | WO2000003706A1 (ru) |
ZA (1) | ZA200100239B (ru) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002069949A2 (en) * | 2001-03-06 | 2002-09-12 | Prendergast Patrick T | Combination therapy for reduction of toxycity of chemotherapeutic agents |
AU2003217982A1 (en) * | 2002-03-06 | 2003-09-22 | The Medical Research And Education Trust | Botanical extract compositions with anti-cancer or phytoestrogenic activity comprising wogonin, isoliquiritigenin and/or coumestrol |
EP1808172A3 (en) * | 2002-03-06 | 2010-05-26 | Activephyto Technologies Limited | Botanical extract compositions and methods of use |
US20030229136A1 (en) | 2002-04-18 | 2003-12-11 | Nurulain Zaveri | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents |
CN1679539A (zh) * | 2005-01-20 | 2005-10-12 | 吴一心 | 抗肿瘤的协同药物组合物 |
US20060247305A1 (en) * | 2005-03-11 | 2006-11-02 | Regents Of The University Of Michigan | Chromen-4-one inhibitors of anti-apoptotic Bcl-2 family members and the uses thereof |
GB0808974D0 (en) * | 2008-05-16 | 2008-06-25 | Veritron Ltd | Plant extract and its therapeutic use |
US9808439B2 (en) * | 2015-07-29 | 2017-11-07 | Macau University Of Science And Technology | Use of tangeretin in cancer treatment |
US9808477B2 (en) * | 2015-07-29 | 2017-11-07 | Macau University Of Science And Technology | Use of nobiletin in cancer treatment |
JP6775226B2 (ja) * | 2016-06-30 | 2020-10-28 | 国立大学法人広島大学 | 抗癌剤作用増強物質およびそれを備えた抗癌剤キット |
CN106562954A (zh) * | 2016-11-11 | 2017-04-19 | 黄冈师范学院 | (去甲基)多甲氧基黄酮联合紫杉醇类药物在制备治疗非小细胞肺癌的药物上的应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0617304B2 (ja) * | 1982-09-09 | 1994-03-09 | 理化学研究所 | 制癌剤 |
JPS5959627A (ja) * | 1982-09-27 | 1984-04-05 | Tatsuo Miyoshi | 制癌剤 |
JPS60199817A (ja) * | 1984-03-23 | 1985-10-09 | Rikagaku Kenkyusho | 制癌剤 |
JPS632925A (ja) * | 1986-06-23 | 1988-01-07 | Nippon Kayaku Co Ltd | Cキナ−ゼ阻害剤および抗腫瘍剤 |
FR2633182B1 (fr) * | 1988-06-23 | 1993-07-23 | Beljanski Mirko | Composition pharmaceutique anticancereuse et methode d'utilisation de l'invention |
JPH04103532A (ja) * | 1990-08-24 | 1992-04-06 | Tatsuo Miyoshi | 制癌剤 |
JPH04103529A (ja) * | 1990-08-24 | 1992-04-06 | Tatsuo Miyoshi | 制癌剤 |
JP2514500B2 (ja) * | 1991-09-14 | 1996-07-10 | 呉羽化学工業株式会社 | 多剤耐性抑制剤及び発現阻害剤 |
AU4272293A (en) * | 1992-05-11 | 1993-12-13 | Tsumura & Co. | Apoptosis inducer |
WO1996031206A2 (en) * | 1995-04-07 | 1996-10-10 | Warner-Lambert Company | Flavones and coumarins as agents for the treatment of atherosclerosis |
DE29719198U1 (de) * | 1997-10-29 | 1998-04-23 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke, 14558 Bergholz-Rehbrücke | Flavono/Flavonoid-Zubereitung |
-
1998
- 1998-07-15 FR FR9809058A patent/FR2781153B1/fr not_active Expired - Fee Related
-
1999
- 1999-07-13 JP JP2000559841A patent/JP2002520356A/ja active Pending
- 1999-07-13 BR BR9912816-0A patent/BR9912816A/pt not_active IP Right Cessation
- 1999-07-13 IL IL14058899A patent/IL140588A0/xx unknown
- 1999-07-13 CA CA002337179A patent/CA2337179A1/en not_active Abandoned
- 1999-07-13 CN CNB998098353A patent/CN1139384C/zh not_active Expired - Fee Related
- 1999-07-13 KR KR1020017000478A patent/KR20020003349A/ko not_active Application Discontinuation
- 1999-07-13 AU AU47890/99A patent/AU4789099A/en not_active Abandoned
- 1999-07-13 WO PCT/FR1999/001714 patent/WO2000003706A1/fr not_active Application Discontinuation
- 1999-07-13 EP EP99931342A patent/EP1096930A1/fr not_active Withdrawn
- 1999-07-13 EA EA200100140A patent/EA200100140A1/ru unknown
-
2001
- 2001-01-09 ZA ZA200100239A patent/ZA200100239B/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL140588A0 (en) | 2002-02-10 |
KR20020003349A (ko) | 2002-01-12 |
ZA200100239B (en) | 2002-01-09 |
FR2781153B1 (fr) | 2001-08-03 |
JP2002520356A (ja) | 2002-07-09 |
CA2337179A1 (en) | 2000-01-27 |
EP1096930A1 (fr) | 2001-05-09 |
CN1139384C (zh) | 2004-02-25 |
FR2781153A1 (fr) | 2000-01-21 |
CN1313765A (zh) | 2001-09-19 |
WO2000003706A1 (fr) | 2000-01-27 |
BR9912816A (pt) | 2001-05-08 |
AU4789099A (en) | 2000-02-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA200100139A1 (ru) | Фармацевтические композиции, содержащие 2-хинолоны | |
EA200001223A1 (ru) | Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола | |
EA200100412A1 (ru) | Замещенные 3-цианохинолины в качестве ингибиторов протеинтирозинкиназ | |
EA200300528A1 (ru) | 1-арил-или 1-алкилсульфонилгетероциклилбензазолы в качестве лигандов 5-гидрокситриптамина-6 | |
EA200001224A1 (ru) | Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола | |
TR200201505T2 (tr) | Terapötik maddeler olarak pirazolopirimidinler | |
EA199900936A1 (ru) | Фунгицидные трифторметилалкиламинотриазолопиримидины | |
EA199800943A1 (ru) | Производные мочевины и их применение в качестве ингибиторов инозин-5`-монофосфат- дегидрогеназы | |
EA200000723A1 (ru) | Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола | |
ATE232862T1 (de) | Oxazolidinon derivate und diese enthaltende pharmazeutische zusammensetzungen | |
TR200200579T2 (tr) | Amino-tirazolpiridin türevleri. | |
EA199800752A1 (ru) | Пентафторбензолсульфонамиды и их аналоги | |
BR9916282A (pt) | Composto, uso de um um composto e método de tratamento | |
EA200200208A1 (ru) | Синергитическая композиция | |
ATE297203T1 (de) | Antithrombotische mitteln | |
EA199900494A1 (ru) | Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола | |
EA200100411A1 (ru) | Замещенные 3-цианохинолины в качестве ингибиторов протеинтирозинкиназ | |
EA200000759A1 (ru) | Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола | |
EA199900421A1 (ru) | Бензонафтиридины в качестве бронхиальных терапевтических средств | |
DK0939627T3 (da) | Pentaflourbenzensulfonamider og analoger | |
EA200300716A1 (ru) | Гетероциклилалкилиндольные или -азаиндольные соединения в качестве лиганд 5-гидрокситриптамина-6 | |
LV12291A (lv) | Savienojums un farmaceitiskas kompozicijas ar triptazes aktivitates izmainam saistitu slimibu arstesanai | |
ES2149305T3 (es) | Compuestos de dibenzoxazepina sustituidos, composiciones farmaceuticas y procedimientos de uso. | |
EA200100516A1 (ru) | Производные 3,3-биарилпиперидина и 2,2-биарилморфолина | |
EA200100140A1 (ru) | Терапевтическая композиция на основе флавоноидов для применения в лечении опухолей цитотоксическими агентами |