EA199900740A1 - Способ получения эпросартана (варианты) - Google Patents

Способ получения эпросартана (варианты)

Info

Publication number
EA199900740A1
EA199900740A1 EA199900740A EA199900740A EA199900740A1 EA 199900740 A1 EA199900740 A1 EA 199900740A1 EA 199900740 A EA199900740 A EA 199900740A EA 199900740 A EA199900740 A EA 199900740A EA 199900740 A1 EA199900740 A1 EA 199900740A1
Authority
EA
Eurasian Patent Office
Prior art keywords
eprosartan
options
obtaining
international
relates
Prior art date
Application number
EA199900740A
Other languages
English (en)
Other versions
EA001659B1 (ru
Inventor
Джозеф Роберт Флисак
Ли Лиу
Клиффорд С. Лабо
Original Assignee
Смитклайн Бичам Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Смитклайн Бичам Корпорейшн filed Critical Смитклайн Бичам Корпорейшн
Publication of EA199900740A1 publication Critical patent/EA199900740A1/ru
Publication of EA001659B1 publication Critical patent/EA001659B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Настоящее изобретение касается способа получения эпросартана.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900740A 1997-02-14 1998-02-13 Способ получения эпросартана (варианты) EA001659B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3819597P 1997-02-14 1997-02-14
PCT/US1998/002412 WO1998035963A1 (en) 1997-02-14 1998-02-13 Process for preparing eprosartan

Publications (2)

Publication Number Publication Date
EA199900740A1 true EA199900740A1 (ru) 2000-02-28
EA001659B1 EA001659B1 (ru) 2001-06-25

Family

ID=21898583

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900740A EA001659B1 (ru) 1997-02-14 1998-02-13 Способ получения эпросартана (варианты)

Country Status (41)

Country Link
US (1) US6172237B1 (ru)
EP (1) EP0970073B1 (ru)
JP (1) JP4537499B2 (ru)
KR (1) KR100573638B1 (ru)
CN (1) CN1085208C (ru)
AP (1) AP1128A (ru)
AR (1) AR011125A1 (ru)
AT (1) ATE280765T1 (ru)
AU (1) AU730383B2 (ru)
BG (1) BG63804B1 (ru)
BR (1) BR9808664A (ru)
CA (1) CA2281708C (ru)
CO (1) CO4950550A1 (ru)
CY (1) CY2555B1 (ru)
CZ (1) CZ296349B6 (ru)
DE (1) DE69827240T2 (ru)
DK (1) DK0970073T3 (ru)
EA (1) EA001659B1 (ru)
EG (1) EG23935A (ru)
ES (1) ES2231963T3 (ru)
HU (1) HU228781B1 (ru)
ID (1) ID23181A (ru)
IL (1) IL131309A (ru)
IN (2) IN187999B (ru)
MA (1) MA24470A1 (ru)
MY (1) MY118704A (ru)
NO (1) NO317194B1 (ru)
NZ (1) NZ337180A (ru)
OA (1) OA11146A (ru)
PE (1) PE59299A1 (ru)
PL (1) PL192838B1 (ru)
PT (1) PT970073E (ru)
RO (1) RO119719B1 (ru)
SA (1) SA98190082B1 (ru)
SI (1) SI0970073T1 (ru)
SK (1) SK285036B6 (ru)
TR (1) TR199901936T2 (ru)
TW (1) TW399050B (ru)
UA (1) UA54487C2 (ru)
WO (1) WO1998035963A1 (ru)
ZA (1) ZA981207B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2097408A4 (en) * 2006-12-27 2010-08-25 Hetero Drugs Ltd IMPROVED PROCESS FOR THE PREPARATION OF EPROSARTAN
US8361507B2 (en) * 2007-07-25 2013-01-29 Hetero Drugs Limited Eprosartan mesylate crystalline particles and a process for preparing pure eprosartan
EP2295430A3 (en) * 2007-07-25 2011-08-03 Hetero Drugs Limited Crystalline solid of eprosartan acetate
WO2009084028A2 (en) * 2007-12-03 2009-07-09 Neuland Laboratories Ltd Improved process for manufacturing anhydrous (e)-3-[2-butyl-1- {(4-carboxyphenyl) methyl}-1h-imidazole-5-yl]-(thiophen-2- ylmethyl)prop-2-enoic acid methane sulfonate
CN101215284B (zh) * 2007-12-31 2010-10-13 浙江华海药业股份有限公司 一种改进的依普罗沙坦的制备方法
WO2009122421A2 (en) * 2008-03-31 2009-10-08 Hetero Research Foundation Improved process for eprosartan intermediate
WO2010023688A2 (en) * 2008-08-25 2010-03-04 Matrix Laboratories Limited An improved process for the preparation of eprosartan
WO2011004384A2 (en) 2009-06-05 2011-01-13 Glochem Industries Limited Process for the preparation of eprosartan
WO2011051975A1 (en) 2009-10-30 2011-05-05 Matrix Laboratories Ltd An improved process for the preparation of pure eprosartanand its pharmaceutical acceptable salts

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185351A (en) * 1989-06-14 1993-02-09 Smithkline Beecham Corporation Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
NZ239161A (en) * 1990-07-31 1994-01-26 Smithkline Beecham Corp Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
DE69133019T2 (de) * 1990-12-14 2002-11-28 Smithkline Beecham Corp., Philadelphia Imidazolyl-alkencarbonsäuren
US5395847A (en) * 1993-12-02 1995-03-07 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
ATE247091T1 (de) * 1994-05-20 2003-08-15 Smithkline Beecham Corp Zwischenprodukte zur herstellung einer pharmazeutisch aktiven verbindung

Also Published As

Publication number Publication date
CY2555B1 (en) 2008-07-02
KR100573638B1 (ko) 2006-04-26
DE69827240D1 (de) 2004-12-02
PE59299A1 (es) 1999-09-09
HUP0001994A2 (hu) 2001-06-28
SK285036B6 (sk) 2006-05-04
NO317194B1 (no) 2004-09-13
IN187999B (ru) 2002-08-03
MA24470A1 (fr) 1998-10-01
JP4537499B2 (ja) 2010-09-01
CN1085208C (zh) 2002-05-22
PL335075A1 (en) 2000-04-10
KR20000071007A (ko) 2000-11-25
MY118704A (en) 2005-01-31
SA98190082B1 (ar) 2006-08-20
AU6150898A (en) 1998-09-08
ZA981207B (en) 1998-11-12
UA54487C2 (ru) 2003-03-17
AP9901620A0 (en) 1999-09-30
US6172237B1 (en) 2001-01-09
ATE280765T1 (de) 2004-11-15
DK0970073T3 (da) 2005-02-21
HU228781B1 (en) 2013-05-28
AR011125A1 (es) 2000-08-02
EP0970073A1 (en) 2000-01-12
CZ285299A3 (cs) 2000-02-16
NZ337180A (en) 2000-11-24
EG23935A (en) 2008-01-14
EA001659B1 (ru) 2001-06-25
PL192838B1 (pl) 2006-12-29
ID23181A (id) 2000-03-23
BG63804B1 (bg) 2003-01-31
CA2281708A1 (en) 1998-08-20
DE69827240T2 (de) 2005-10-13
IN192743B (ru) 2004-05-15
ES2231963T3 (es) 2005-05-16
IL131309A0 (en) 2001-01-28
IL131309A (en) 2002-09-12
CN1247539A (zh) 2000-03-15
EP0970073A4 (en) 2001-01-24
WO1998035963A1 (en) 1998-08-20
AU730383B2 (en) 2001-03-08
JP2001510466A (ja) 2001-07-31
CA2281708C (en) 2007-08-14
HUP0001994A3 (en) 2001-07-30
BG103650A (en) 2000-06-30
OA11146A (en) 2003-04-16
SI0970073T1 (en) 2005-02-28
NO993913L (no) 1999-08-13
SK108799A3 (en) 2000-05-16
BR9808664A (pt) 2000-07-11
RO119719B1 (ro) 2005-02-28
AP1128A (en) 2002-12-06
PT970073E (pt) 2005-02-28
CZ296349B6 (cs) 2006-02-15
NO993913D0 (no) 1999-08-13
TR199901936T2 (xx) 2000-04-21
TW399050B (en) 2000-07-21
CO4950550A1 (es) 2000-09-01
EP0970073B1 (en) 2004-10-27

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU