DK3888674T3 - Behandling af cancer ved anvendelse af anti-cd19-kimær antigenreceptor - Google Patents

Behandling af cancer ved anvendelse af anti-cd19-kimær antigenreceptor Download PDF

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Publication number
DK3888674T3
DK3888674T3 DK21160203.2T DK21160203T DK3888674T3 DK 3888674 T3 DK3888674 T3 DK 3888674T3 DK 21160203 T DK21160203 T DK 21160203T DK 3888674 T3 DK3888674 T3 DK 3888674T3
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Prior art keywords
cancer
treatment
antigen receptor
chimeric antigen
chimeric
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DK21160203.2T
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English (en)
Inventor
John Byrd
Jason Dubovsky
Joseph Fraietta
Saar Gill
David Glass
Amy Johnson
Carl H June
Saad Kenderian
Joan Mannick
Marcela Maus
Leon Murphy
Natarajan Muthusamy
David L Porter
Marco Ruella
William Raj Sellers
Mariusz Wasik
Jennifer Brogdon
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Novartis Ag
Univ Pennsylvania
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • AHUMAN NECESSITIES
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    • A61K2239/26Universal/off- the- shelf cellular immunotherapy; Allogenic cells or means to avoid rejection
    • AHUMAN NECESSITIES
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    • A61K2239/31Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61K2239/46Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/48Blood cells, e.g. leukemia or lymphoma
    • AHUMAN NECESSITIES
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K39/4644Cancer antigens
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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DK21160203.2T 2014-04-07 2015-04-07 Behandling af cancer ved anvendelse af anti-cd19-kimær antigenreceptor DK3888674T3 (da)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201461976396P 2014-04-07 2014-04-07
US201462007309P 2014-06-03 2014-06-03
US201462036493P 2014-08-12 2014-08-12
US201462076238P 2014-11-06 2014-11-06
US201462087888P 2014-12-05 2014-12-05
US201462097278P 2014-12-29 2014-12-29
EP15719043.0A EP3129470B1 (en) 2014-04-07 2015-04-07 Treatment of cancer using anti-cd19 chimeric antigen receptor

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DK3888674T3 true DK3888674T3 (da) 2024-07-08

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DK21160203.2T DK3888674T3 (da) 2014-04-07 2015-04-07 Behandling af cancer ved anvendelse af anti-cd19-kimær antigenreceptor

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EP (3) EP4406610A3 (da)
JP (3) JP6765966B2 (da)
KR (3) KR102487608B1 (da)
CN (2) CN107075482B (da)
AU (2) AU2015244039B2 (da)
CA (1) CA2940671A1 (da)
DK (2) DK3129470T3 (da)
ES (1) ES2876263T3 (da)
FI (1) FI3888674T3 (da)
HR (2) HRP20240874T1 (da)
HU (2) HUE054588T2 (da)
IL (4) IL307423A (da)
LT (2) LT3888674T (da)
MX (2) MX2016013239A (da)
MY (1) MY191608A (da)
PL (2) PL3888674T3 (da)
PT (2) PT3888674T (da)
RU (1) RU2718542C2 (da)
SG (2) SG11201606909RA (da)
SI (2) SI3888674T1 (da)
TW (1) TWI753848B (da)
WO (1) WO2015157252A1 (da)
ZA (1) ZA201605657B (da)

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US9249423B2 (en) 2007-02-02 2016-02-02 Yale University Method of de-differentiating and re-differentiating somatic cells using RNA
WO2010099205A1 (en) * 2009-02-24 2010-09-02 The Trustees Of The University Of Pennsylvania Methods for treating progressive multifocal leukoencephalopathy (pml)
US10940169B2 (en) 2015-11-30 2021-03-09 Joseph E. Kovarik Method for reducing the likelihood of developing cancer in an individual human being
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
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