DK37789A - Antikoagulerende middel samt anvendelse heraf - Google Patents

Antikoagulerende middel samt anvendelse heraf

Info

Publication number
DK37789A
DK37789A DK037789A DK37789A DK37789A DK 37789 A DK37789 A DK 37789A DK 037789 A DK037789 A DK 037789A DK 37789 A DK37789 A DK 37789A DK 37789 A DK37789 A DK 37789A
Authority
DK
Denmark
Prior art keywords
anticoagulant
anticoagulating agent
activity
heparin
activated protein
Prior art date
Application number
DK037789A
Other languages
English (en)
Other versions
DK37789D0 (da
Inventor
Keizo Hirahara
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11897770&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK37789(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst Japan filed Critical Hoechst Japan
Publication of DK37789D0 publication Critical patent/DK37789D0/da
Publication of DK37789A publication Critical patent/DK37789A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4866—Protein C (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Paper (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK037789A 1988-01-28 1989-01-27 Antikoagulerende middel samt anvendelse heraf DK37789A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63015761A JP2739050B2 (ja) 1988-01-28 1988-01-28 抗血液凝固剤

Publications (2)

Publication Number Publication Date
DK37789D0 DK37789D0 (da) 1989-01-27
DK37789A true DK37789A (da) 1989-07-29

Family

ID=11897770

Family Applications (1)

Application Number Title Priority Date Filing Date
DK037789A DK37789A (da) 1988-01-28 1989-01-27 Antikoagulerende middel samt anvendelse heraf

Country Status (13)

Country Link
US (1) US5084273A (da)
EP (1) EP0326014B1 (da)
JP (1) JP2739050B2 (da)
KR (1) KR0127754B1 (da)
AT (1) ATE74273T1 (da)
AU (1) AU607303B2 (da)
CA (1) CA1330299C (da)
DE (1) DE68901098D1 (da)
DK (1) DK37789A (da)
ES (1) ES2039709T3 (da)
GR (1) GR3005040T3 (da)
IE (1) IE63528B1 (da)
PT (1) PT89534B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8822147D0 (en) * 1988-09-21 1988-10-26 Ciba Geigy Ag Pharmaceutically active combination
SE464135B (sv) * 1989-07-14 1991-03-11 Kabivitrum Ab Foerfarande foer bestaemning av funktionell aktivitet av fritt protein s eller protein c i ett plasmaprov
AT402260B (de) * 1990-08-16 1997-03-25 Immuno Ag Protein c-hältige pharmazeutische präparation
US5571786A (en) * 1990-08-16 1996-11-05 Immuno Aktiengesellschaft Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation
FR2671973A1 (fr) * 1991-01-25 1992-07-31 Fondation Nale Transfusion San Utilisation de la proteine c activee comme agent anti-agregant plaquettaire.
AT402263B (de) * 1991-06-20 1997-03-25 Immuno Ag Pharmazeutische präparation enthaltend eine thrombolytisch wirkende substanz
WO1994002172A1 (en) 1992-07-24 1994-02-03 Oklahoma Medical Research Foundation Blockade of protein c activation reduces microvascular surgical blood loss
JP3711561B2 (ja) * 1993-04-05 2005-11-02 三菱ウェルファーマ株式会社 アンチトロンビン−▲ｉｉｉ▼液状製剤およびその安定化方法
DE4320294A1 (de) * 1993-06-18 1994-12-22 Immuno Ag Verwendung von humanem Protein C zur Verhinderung und Behandlung von Thrombozytenablagerungen
US5516889A (en) * 1993-06-21 1996-05-14 University Technologies International, Inc. Synthetic thrombin receptor peptides
WO1995030429A1 (en) * 1994-05-04 1995-11-16 Board Of Trustees Of The University Of Arkansas Novel ophthalmologic uses of protein c
JPH08224227A (ja) * 1995-02-22 1996-09-03 Internatl Reagents Corp 血液採血管
US6491965B1 (en) 1995-11-30 2002-12-10 Hamilton Civic Hospitals Research Development, Inc. Medical device comprising glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
US6562781B1 (en) 1995-11-30 2003-05-13 Hamilton Civic Hospitals Research Development Inc. Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
US7045585B2 (en) * 1995-11-30 2006-05-16 Hamilton Civic Hospital Research Development Inc. Methods of coating a device using anti-thrombin heparin
PL195642B1 (pl) 1997-04-28 2007-10-31 Lilly Co Eli Sposób przetwarzania wodnego roztworu aktywowanego białka C
US6630137B1 (en) 1997-04-28 2003-10-07 Eli Lilly And Company Activated protein C formulations
PL337223A1 (en) * 1997-06-05 2000-08-14 Lilly Co Eli Method of treating thrombotic disorders
GB9711927D0 (en) * 1997-06-09 1997-08-06 Bristol Myers Squibb Co Compositions useful as fibrin sealants
US7204981B2 (en) 2000-03-28 2007-04-17 Eli Lilly And Company Methods of treating diseases with activated protein C
EP1289543A2 (en) 2000-05-24 2003-03-12 Eli Lilly And Company Formulations and methods for treating hypercoagulable states
DE10045047A1 (de) * 2000-09-12 2002-03-21 Beate Kehrel Arzneimittel enthaltend aktiviertes Antithrombin III
JP2004535461A (ja) * 2001-07-19 2004-11-25 ディーエムアイ バイオサイエンシズ インコーポレイテッド プロテインｃの不活性化を抑制するための銅キレート剤の使用
AU2003213146A1 (en) * 2002-03-08 2003-09-22 Eli Lilly And Company Activated protein c formulations
JP5506403B2 (ja) * 2008-01-29 2014-05-28 協和発酵キリン株式会社 神経幹細胞増殖促進剤
WO2024003418A1 (en) 2022-07-01 2024-01-04 Universiteit Maastricht Improved downregulation of histone cytotoxicity by complex of negatively charged polysaccharide and protease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8319538D0 (en) * 1983-07-20 1983-08-24 Beecham Group Plc Compounds

Also Published As

Publication number Publication date
ES2039709T3 (es) 1993-10-01
ATE74273T1 (de) 1992-04-15
GR3005040T3 (da) 1993-05-24
KR0127754B1 (ko) 1998-04-01
EP0326014A1 (en) 1989-08-02
JPH01193229A (ja) 1989-08-03
JP2739050B2 (ja) 1998-04-08
AU607303B2 (en) 1991-02-28
AU2885589A (en) 1989-08-03
US5084273A (en) 1992-01-28
PT89534A (pt) 1989-10-04
KR890011606A (ko) 1989-08-21
IE890269L (en) 1989-07-28
PT89534B (pt) 2001-05-31
CA1330299C (en) 1994-06-21
DE68901098D1 (de) 1992-05-07
DK37789D0 (da) 1989-01-27
EP0326014B1 (en) 1992-04-01
IE63528B1 (en) 1995-05-03

Similar Documents

Publication Publication Date Title
DK37789A (da) Antikoagulerende middel samt anvendelse heraf
HK45193A (en) Ozone decontamination of blood and blood products
ES2058725T3 (es) Aplicacion transdermica de 2-amino-6-n-propilamino-4,5,6,7-tetrahidrobenzotiazol.
DE3687741D1 (de) Geraet zur ultraschallechographie der bewegung von koerperorganen, insbesondere der blutstroemung oder des herzens.
NO893637D0 (no) Fremgangsmaate for aa stabilisere blodkoagulasjonsfaktorer.
DK261490D0 (da) New pharmaceutical compound
LV12000A (lv) Olbaltumviela ar uratoksidazes aktivitati un tas iegusana
FI98334B (fi) Menetelmä silmänesteen säilömiseksi sekä säilötyn silmänesteen käyttö
DK226889D0 (da) Alkoholpeptidderivat samt anvendelse deraf til mindskning af blodkoagulation
DE3852227D1 (de) Immunologisches Nachweisverfahren für Herbizide.
BR8907503A (pt) Hidrofluoracao de alcanos halogenados catalisada com tax5
DE68907083D1 (de) Abkoemmlinge von 2-cyclopentenon.
DK191089A (da) Biologisk aktive forbindelser
ES2000033A6 (es) Composicion de bitionol sulfoxido porcedimiento para su fabricacion y metodo de utilizacion de aquella
AU4266289A (en) Antidote
NO166225C (no) Fluorborsyresalt av n-tridecyl-2,6-dimetylmorfolin, fungicid og trebeskyttelsesmiddel inneholdende dette, samt anvendelse derav.
DE3876425D1 (de) Gesteuerte verabreichung eines heilmittels an blut.
DE69005052D1 (de) Katalytische Herstellung von optisch aktiven Ketonen.
DE3675069D1 (de) Carboxanilide.
DE3481814D1 (de) Kosmetikum.
KR910700061A (ko) 인터로이킨-1β의 안정화 조성물
DE68905178D1 (de) Stabile waessrige zubereitung von aktivem vitamin-d-3.
MX9203658A (es) Derivados de piridobenzoxazina opticamente activos, y su uso antimicrobiano.
FI915571A (fi) Trombinbindande substans och foerfarande foer dess framstaellning.
ATE104966T1 (de) 9-(acylamino)tetrahydroacridinderivate und wahrnehmungssteigernde mittel davon als aktiver wirkstoff.

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment