DK3548061T3 - Behandling af neurologiske sygdomme - Google Patents

Behandling af neurologiske sygdomme Download PDF

Info

Publication number
DK3548061T3
DK3548061T3 DK17811693.5T DK17811693T DK3548061T3 DK 3548061 T3 DK3548061 T3 DK 3548061T3 DK 17811693 T DK17811693 T DK 17811693T DK 3548061 T3 DK3548061 T3 DK 3548061T3
Authority
DK
Denmark
Prior art keywords
treatment
neurological diseases
neurological
diseases
Prior art date
Application number
DK17811693.5T
Other languages
English (en)
Inventor
Christian Hölscher
Original Assignee
Lancaster Univ Business Enterprises Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lancaster Univ Business Enterprises Limited filed Critical Lancaster Univ Business Enterprises Limited
Application granted granted Critical
Publication of DK3548061T3 publication Critical patent/DK3548061T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
DK17811693.5T 2016-12-05 2017-12-04 Behandling af neurologiske sygdomme DK3548061T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1620611.2A GB201620611D0 (en) 2016-12-05 2016-12-05 Treatment of neurological diseases
PCT/GB2017/053655 WO2018104718A1 (en) 2016-12-05 2017-12-04 Treatment of neurological diseases

Publications (1)

Publication Number Publication Date
DK3548061T3 true DK3548061T3 (da) 2020-12-14

Family

ID=58159786

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17811693.5T DK3548061T3 (da) 2016-12-05 2017-12-04 Behandling af neurologiske sygdomme

Country Status (24)

Country Link
US (2) US11220534B2 (da)
EP (1) EP3548061B1 (da)
JP (1) JP7099729B2 (da)
KR (1) KR102600128B1 (da)
CN (1) CN110312520B (da)
AU (1) AU2017371811B2 (da)
BR (1) BR112019011462A2 (da)
CA (1) CA3044797A1 (da)
CL (1) CL2019001512A1 (da)
CO (1) CO2019006979A2 (da)
CY (1) CY1123623T1 (da)
DK (1) DK3548061T3 (da)
ES (1) ES2833408T3 (da)
GB (1) GB201620611D0 (da)
HR (1) HRP20201959T1 (da)
HU (1) HUE052766T2 (da)
LT (1) LT3548061T (da)
MX (1) MX2019006495A (da)
PT (1) PT3548061T (da)
RS (1) RS61230B1 (da)
RU (1) RU2755997C2 (da)
SI (1) SI3548061T1 (da)
WO (1) WO2018104718A1 (da)
ZA (1) ZA201903003B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201620611D0 (en) * 2016-12-05 2017-01-18 Univ Of Lancaster Treatment of neurological diseases
TW202228762A (zh) * 2020-01-30 2022-08-01 美商美國禮來大藥廠 提派肽(tirzepatide)之治療用途
US20230272029A1 (en) 2020-07-22 2023-08-31 Novo Nordisk A/S Co-agonists at glp-1 and gip receptors suitable for oral delivery
JP2023543036A (ja) * 2020-09-25 2023-10-12 ハンミ ファーマシューティカル カンパニー リミテッド グルカゴン、glp-1及びgip受容体の全てに対して活性を有する三重活性体またはその結合体の神経退行性疾患の治療用途
CN114617956B (zh) * 2020-12-10 2023-10-03 江苏中新医药有限公司 一种高效降糖的蛋白质药物
CN114042149B (zh) * 2021-12-03 2023-06-16 中国人民解放军空军军医大学 D-Ala2-GIP用于制备治疗焦虑症药物的应用
TW202330584A (zh) 2022-01-20 2023-08-01 丹麥商諾佛 儂迪克股份有限公司 前藥及其用途
WO2023151594A1 (en) * 2022-02-11 2023-08-17 Hangzhou Sciwind Biosciences Co., Ltd. A composition comprising gip receptor agonists and glp-1 receptor agonists and use thereof
WO2024209050A1 (en) 2023-04-05 2024-10-10 Antag Therapeutics Aps Gip activity modulators and orthostatic intolerance

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI406671B (zh) * 2006-01-05 2013-09-01 Univ Utah Res Found 改善以神經系統為標的之藥劑之性質之方法及組合物
EP2952202B1 (en) * 2008-06-17 2017-10-18 Indiana University Research and Technology Corporation Gip-based mixed agonists for treatment of metabolic disorders and obesity
WO2010043047A1 (en) 2008-10-15 2010-04-22 Angiochem Inc. Conjugates of glp-1 agonists and uses thereof
JP2013518115A (ja) 2010-01-27 2013-05-20 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション 代謝疾患及び肥満の治療のためのグルカゴンアンタゴニスト‐gipアゴニスト複合体及び組成物
KR101893473B1 (ko) 2010-09-28 2018-08-30 노노 인코포레이티드 신경계 질병을 치료하는 nd2 펩티드 및 방법
AR087744A1 (es) * 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
EP2766094B1 (en) 2011-10-10 2019-03-06 Lancaster University Business Enterprises Limited Compositions for binding to amyloid proteins
CN104470948B (zh) 2012-05-03 2018-06-15 西兰制药公司 Gip-glp-1双激动剂化合物及方法
RU2015101697A (ru) * 2012-06-21 2016-08-10 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Аналоги глюкагона, обладающие активностью рецептора gip
RS60625B1 (sr) * 2014-05-28 2020-09-30 Nono Inc Hloridna so tat-nr2b9c
GB2528436A (en) 2014-07-15 2016-01-27 Lancaster Univ Business Entpr Ltd Treatment of neurological diseases
US20160143920A1 (en) * 2014-10-22 2016-05-26 Morris Notelovitz Composition, formulations and methods of making and using botanicals and natural compounds for the promotion of healthy brain aging
US20170112897A1 (en) 2015-10-23 2017-04-27 Cedars-Sinai Medical Center Methods for treating brain insulin resistance
CN108473547A (zh) 2015-10-28 2018-08-31 塔夫茨大学 具有改良的蛋白质分解安定性的新颖多肽,以及制备与使用该新颖多肽的方法
WO2017210168A1 (en) 2016-06-02 2017-12-07 Indiana University Research And Technology Corporation Aqueously soluble and chemically stable depsi glucagon agonists
GB201620611D0 (en) * 2016-12-05 2017-01-18 Univ Of Lancaster Treatment of neurological diseases

Also Published As

Publication number Publication date
US11220534B2 (en) 2022-01-11
HRP20201959T1 (hr) 2021-04-16
AU2017371811A1 (en) 2019-06-13
EP3548061B1 (en) 2020-09-09
RS61230B1 (sr) 2021-01-29
RU2019118165A3 (da) 2021-03-05
CA3044797A1 (en) 2018-06-14
EP3548061A1 (en) 2019-10-09
KR102600128B1 (ko) 2023-11-08
JP2020504713A (ja) 2020-02-13
WO2018104718A1 (en) 2018-06-14
GB201620611D0 (en) 2017-01-18
ZA201903003B (en) 2019-12-18
LT3548061T (lt) 2020-12-28
JP7099729B2 (ja) 2022-07-12
CY1123623T1 (el) 2022-03-24
KR20190101367A (ko) 2019-08-30
MX2019006495A (es) 2019-11-05
CN110312520A (zh) 2019-10-08
CL2019001512A1 (es) 2019-11-22
US20220033457A1 (en) 2022-02-03
US11851468B2 (en) 2023-12-26
SI3548061T1 (sl) 2021-04-30
CN110312520B (zh) 2023-01-24
BR112019011462A2 (pt) 2019-10-22
RU2755997C2 (ru) 2021-09-24
PT3548061T (pt) 2020-11-24
ES2833408T3 (es) 2021-06-15
US20200079832A1 (en) 2020-03-12
RU2019118165A (ru) 2021-01-11
AU2017371811B2 (en) 2022-03-10
CO2019006979A2 (es) 2019-09-09
HUE052766T2 (hu) 2021-05-28

Similar Documents

Publication Publication Date Title
DK3448999T3 (da) Oligonukleotider til behandling af øjensygdom
DK3777855T3 (da) Fremgangsmåder til behandling af fibrotiske sygdomme
DK3728271T3 (da) Makrocykliske forbindelser til behandling af sygdomme
DK3347030T3 (da) Brug af pasteuriseret akkermansia til behandling af stofskiftesygdomme
DK3450553T3 (da) Mrna-terapi til behandling af øjensygdomme
DK3212233T3 (da) Kombinationsterapi til behandling af sygdom
DK3326641T3 (da) Rna-holdig sammensætning til behandling af tumorsygdomme
DK3548061T3 (da) Behandling af neurologiske sygdomme
DK3851537T3 (da) Behandling af hyperbilirubinæmi
DK3240612T3 (da) Fremgangsmåder til behandling af nethindesygdomme
DK3390390T3 (da) Bipyrazolylderivater egnede til behandling af autoimmunsygdomme
DK3609529T3 (da) Rna til behandling af autoimmune sygdomme
DK3169328T3 (da) Quinolinderivater til behandling af inflammationssygdomme
DK3458052T3 (da) Kombinationsbehandling af cancer
DK3498278T3 (da) Forbindelser til behandling af sygdomme relateret til DUX4-ekspression
DK3419622T3 (da) Behandling af neurodegenerativ øjensygdom med pridopidin
DK3307267T3 (da) Behandling af multipel sklerose
DK3430143T3 (da) Inhibitorer af SRSF1 til behandlingen af neurodegenerative sygdomme
DK3210973T3 (da) Heteroarylforbindelser til behandling af oftalmiske sygdomme
DK3164394T3 (da) Gls1-inhibitorer til behandling af sygdomme
DK3192524T3 (da) Hgf præparat egnet til behandling af neurologiske lidelser
DK3439661T3 (da) Fremgangsmåder til behandling af øjenlidelser
DK3578562T3 (da) L-valinatamidbenzoxaborolderivater til behandling af parasitiske sygdomme
DK3297619T3 (da) Terapeutiske anvendelser af L-4-chlorkynurenin
DK3848028T3 (da) Fremgangsmåder til behandling af øjenlidelser