DK315876A - 1,3,8-triazaspiro(4,5)decan-4-onderivater samt fremgangsmade til fremstilling heraf - Google Patents

1,3,8-triazaspiro(4,5)decan-4-onderivater samt fremgangsmade til fremstilling heraf

Info

Publication number
DK315876A
DK315876A DK315876A DK315876A DK315876A DK 315876 A DK315876 A DK 315876A DK 315876 A DK315876 A DK 315876A DK 315876 A DK315876 A DK 315876A DK 315876 A DK315876 A DK 315876A
Authority
DK
Denmark
Prior art keywords
underivatives
triazaspiro
decan
procedures
preparation
Prior art date
Application number
DK315876A
Other languages
English (en)
Inventor
B R Vogt
D A Cullison
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of DK315876A publication Critical patent/DK315876A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/26Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/32Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by introduction of halogenated alkyl groups into ring compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK315876A 1975-07-14 1976-07-13 1,3,8-triazaspiro(4,5)decan-4-onderivater samt fremgangsmade til fremstilling heraf DK315876A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59594775A 1975-07-14 1975-07-14
US05/688,438 US4051248A (en) 1975-07-14 1976-05-20 1,3,8-triazaspiro(4.5)decan-4-one derivatives

Publications (1)

Publication Number Publication Date
DK315876A true DK315876A (da) 1977-01-15

Family

ID=27082415

Family Applications (1)

Application Number Title Priority Date Filing Date
DK315876A DK315876A (da) 1975-07-14 1976-07-13 1,3,8-triazaspiro(4,5)decan-4-onderivater samt fremgangsmade til fremstilling heraf

Country Status (17)

Country Link
US (1) US4051248A (da)
JP (1) JPS5212175A (da)
CA (1) CA1088541A (da)
CH (1) CH614210A5 (da)
DD (1) DD128110A5 (da)
DE (1) DE2630602A1 (da)
DK (1) DK315876A (da)
ES (1) ES449797A1 (da)
FR (1) FR2317928A1 (da)
GB (1) GB1547597A (da)
IE (1) IE44154B1 (da)
NL (1) NL7607691A (da)
NO (1) NO762447L (da)
NZ (1) NZ181287A (da)
PH (1) PH12281A (da)
SE (1) SE7608004L (da)
SU (1) SU656519A3 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR73633B (da) * 1980-03-10 1984-03-26 Janssen Pharmaceutica Nv
US4329353A (en) * 1980-10-22 1982-05-11 Janssen Pharmaceutica, N.V. 1-(4-Aryl-cyclohexyl)piperidine derivatives, method of use thereof and pharmaceutical compositions thereof
US4374245A (en) * 1982-04-09 1983-02-15 Hoechst-Roussel Pharmaceuticals Inc. 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
GB8515386D0 (en) * 1985-06-18 1985-07-17 Ici Plc Organic compounds
US4707484A (en) * 1986-11-25 1987-11-17 Hoffmann-La Roche Inc. Substituted piperidinomethylindolone and cyclopent(b)indolone derivatives
JP2002515503A (ja) * 1998-05-18 2002-05-28 ノボ ノルディスク アクティーゼルスカブ オピオイド受容体のサブタイプへの高い親和性を有する新規1,3,8−トリアザスピロ〔4,5〕デカノン
US6277991B1 (en) 1998-05-18 2001-08-21 Novo Nordisk A/S 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes
EP0997464B1 (en) * 1998-10-23 2005-02-16 Pfizer Inc. 1,3,8-Triazaspiro[4,5] decanone compounds as orl1-receptor agonists
DE60033071T2 (de) * 1999-12-06 2007-08-23 Euro-Celtique S.A. Triazospiroverbindungen mit nociceptin-rezeptoraffinität

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923794A (en) * 1971-08-26 1975-12-02 Sumitomo Chemical Co Novel propenylamine derivatives and process for the production thereof
BE792187A (fr) * 1971-12-03 1973-03-30 Sumitomo Chemical Co Nouveaux derives d'alkylamines
US3922266A (en) * 1972-06-28 1975-11-25 Sumitomo Chemical Co Aryl ketones and production thereof
JPS49101383A (da) * 1973-02-05 1974-09-25

Also Published As

Publication number Publication date
PH12281A (en) 1978-12-12
GB1547597A (en) 1979-06-20
DD128110A5 (de) 1977-11-02
FR2317928A1 (fr) 1977-02-11
CA1088541A (en) 1980-10-28
IE44154B1 (en) 1981-08-26
US4051248A (en) 1977-09-27
JPS5212175A (en) 1977-01-29
SE7608004L (sv) 1977-01-15
SU656519A3 (ru) 1979-04-05
IE44154L (en) 1977-01-14
CH614210A5 (da) 1979-11-15
ES449797A1 (es) 1978-01-01
FR2317928B1 (da) 1978-11-17
NL7607691A (nl) 1977-01-18
NZ181287A (en) 1978-06-20
NO762447L (da) 1977-01-17
DE2630602A1 (de) 1977-02-03

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