DK2755980T3 - Fremgangsmåder og systemer til dannelse boronsyre og mellemprodukter deraf - Google Patents

Fremgangsmåder og systemer til dannelse boronsyre og mellemprodukter deraf Download PDF

Info

Publication number: DK2755980T3
Authority: DK; Denmark
Prior art keywords: intermediates; procedures; creating; systems; boronic acid
Prior art date: 2011-09-14

Application number

DK12832249.2T

Other languages

English (en)

Inventor

Catherine A Menning

D Wayne Blaylock

Mark V M Emonds

Original Assignee

Dow Agrosciences Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-09-14

Filing date

2012-09-14

Publication date

2020-01-27

2012-09-14 Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc

2020-01-27 Application granted granted Critical

2020-01-27 Publication of DK2755980T3 publication Critical patent/DK2755980T3/da

Links

ZADPBFCGQRWHPN-UHFFFAOYSA-N boronic acid Chemical compound OBO ZADPBFCGQRWHPN-UHFFFAOYSA-N 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/24—Stationary reactors without moving elements inside
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/02—Lithium compounds
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00002—Chemical plants
- B01J2219/00004—Scale aspects
- B01J2219/00011—Laboratory-scale plants
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00002—Chemical plants
- B01J2219/00027—Process aspects
- B01J2219/0004—Processes in series
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00051—Controlling the temperature
- B01J2219/00074—Controlling the temperature by indirect heating or cooling employing heat exchange fluids
- B01J2219/00087—Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements outside the reactor
- B01J2219/00094—Jackets
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00051—Controlling the temperature
- B01J2219/00074—Controlling the temperature by indirect heating or cooling employing heat exchange fluids
- B01J2219/00087—Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements outside the reactor
- B01J2219/00099—Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements outside the reactor the reactor being immersed in the heat exchange medium
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/0059—Sequential processes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00788—Three-dimensional assemblies, i.e. the reactor comprising a form other than a stack of plates
- B01J2219/00792—One or more tube-shaped elements
- B01J2219/00795—Spiral-shaped
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00801—Means to assemble
- B01J2219/0081—Plurality of modules
- B01J2219/00813—Fluidic connections
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00822—Metal
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00851—Additional features
- B01J2219/00858—Aspects relating to the size of the reactor
- B01J2219/0086—Dimensions of the flow channels
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00851—Additional features
- B01J2219/00867—Microreactors placed in series, on the same or on different supports
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00873—Heat exchange
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00891—Feeding or evacuation
- B01J2219/00894—More than two inlets

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Materials Engineering (AREA)

DK12832249.2T 2011-09-14 2012-09-14 Fremgangsmåder og systemer til dannelse boronsyre og mellemprodukter deraf DK2755980T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201161534768P	2011-09-14	2011-09-14
PCT/US2012/055605 WO2013040479A1 (en)	2011-09-14	2012-09-14	Methods and systems for forming boronic acids and intermediates thereof

Publications (1)

Publication Number	Publication Date
DK2755980T3 true DK2755980T3 (da)	2020-01-27

Family

ID=47830429

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK12832249.2T DK2755980T3 (da)	2011-09-14	2012-09-14	Fremgangsmåder og systemer til dannelse boronsyre og mellemprodukter deraf

Country Status (14)

Country	Link
US (1)	US9145428B2 (da)
EP (1)	EP2755980B1 (da)
JP (3)	JP6425543B2 (da)
KR (2)	KR20140061505A (da)
CN (1)	CN103827124B (da)
CA (1)	CA2847858A1 (da)
CO (1)	CO6930354A2 (da)
DK (1)	DK2755980T3 (da)
HK (1)	HK1199262A1 (da)
IL (1)	IL231391A (da)
MX (1)	MX2014003064A (da)
PL (1)	PL2755980T3 (da)
RU (1)	RU2607941C2 (da)
WO (1)	WO2013040479A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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FR3012145B1 (fr) *	2013-10-18	2015-12-18	Yriel	Procede continu de preparation d'acides boroniques et de leurs derives
US9771380B2 (en) *	2014-06-09	2017-09-26	University Of Oregon	Gold nanoparticles and methods of making and using gold nanoparticles
CN105056842B (zh) *	2015-07-23	2017-12-15	厦门大学	一种反应装置及其在合成硼酸酯中的应用
CN106422985A (zh) *	2016-11-30	2017-02-22	南京睿宇物联网科技有限公司	用于安全添加叔丁基锂至反应器的反应系统
JOP20190188A1 (ar)	2017-02-01	2019-08-01	Rempex Pharmaceuticals Inc	جهاز وعملية تدفق مستمرة لإنتاج مشتق حمض بورونيك
CN115279737A (zh)	2020-03-18	2022-11-01	科迪华农业科技有限责任公司	4-氨基-6-(杂环)吡啶甲酸酯的改进合成
EP4121416A1 (en)	2020-03-18	2023-01-25	Corteva Agriscience LLC	Improved synthesis of 6-aryl-4-aminopicolinates
MX2023008521A (es)	2021-01-21	2023-07-28	Corteva Agriscience Llc	Procesos relacionados con la formacion de n-(3-cloro-1-(piridin-3- il)-1h-pirazol-4-il)-2-(metilsulfonil)propanamida.
CN112979688B (zh) *	2021-05-20	2022-02-01	凯莱英医药集团（天津）股份有限公司	2-氟-4-三氟甲基苯硼酸的制备方法

Family Cites Families (16)

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DE19858856A1 (de) *	1998-12-19	2000-06-21	Merck Patent Gmbh	Verfahren zur Herstellung von Arylmetallverbindungen und deren Umsetzung mit Elektrophilen
CA2431904A1 (en) *	2000-12-20	2002-08-01	Merck & Co., Inc.	(halo-benzo carbonyl)heterocyclo fused phenyl p38 kinase inhibiting agents
DE10110051C2 (de) *	2001-03-02	2003-07-03	Clariant Gmbh	Verfahren zur Herstellung von Boron- und Borinsäuren
DE10139664A1 (de) *	2001-08-11	2003-02-20	Clariant Gmbh	Verfahren zur Herstellung von Aryl- und Alkyl-Bor-Verbindungen in Mikroreaktoren
DE10150615A1 (de) *	2001-10-12	2003-04-30	Clariant Gmbh	Verfahren zur metallorganischen Herstellung organischer Zwischenprodukte
CA2482022A1 (en) *	2002-04-19	2003-10-30	Smithkline Beecham Corporation	Novel compounds
JP4639042B2 (ja) *	2003-09-29	2011-02-23	富士フイルムファインケミカルズ株式会社	ハロゲン−リチウム交換反応を用いる有機化合物の製造法
FR2864083B1 (fr) *	2003-12-18	2007-04-13	Galderma Res & Dev	Nouveaux derives d'acides phenyl-boroniques et leurs procedes de preparation.
DE102005037547A1 (de)	2005-08-09	2007-02-15	Basf Ag	Verfahren zur Herstellung von Arylboronsäureestern
DE602007008052D1 (de)	2006-01-13	2010-09-09	Dow Agrosciences Llc	2-(polysubstituiertes aryl)-6-amino-5-halogen-4-pyrimidincarbonsäuren und deren verwendung als herbizide
AU2007204825B2 (en) *	2006-01-13	2011-07-14	Corteva Agriscience Llc	6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides
US7998418B1 (en) *	2006-06-01	2011-08-16	Nanotek, Llc	Evaporator and concentrator in reactor and loading system
BRPI0816075A2 (pt) *	2007-08-30	2015-02-24	Dow Agrosciences Llc	2-(fenil substituído)-6-amino-5-alcóxi, tioalcóxi e aminoalquil-4-pirimidinacarboxilatos e seus usos como herbicidas
US7611647B2 (en) *	2008-01-11	2009-11-03	Dow Agrosciences Llc	Process for the selective deprotonation and functionalization of 1-fluoro-2-substituted-3-chlorobenzenes
BRPI0923337B8 (pt) *	2008-12-25	2021-08-17	Nippon Soda Co	processo para produzir composto de organolítio, processo para produzir composto aromático substituído e ligante
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2012
- 2012-09-14 DK DK12832249.2T patent/DK2755980T3/da active
- 2012-09-14 CA CA2847858A patent/CA2847858A1/en not_active Abandoned
- 2012-09-14 EP EP12832249.2A patent/EP2755980B1/en active Active
- 2012-09-14 MX MX2014003064A patent/MX2014003064A/es unknown
- 2012-09-14 US US13/618,128 patent/US9145428B2/en active Active
- 2012-09-14 JP JP2014530900A patent/JP6425543B2/ja active Active
- 2012-09-14 RU RU2014114533A patent/RU2607941C2/ru active
- 2012-09-14 WO PCT/US2012/055605 patent/WO2013040479A1/en active Application Filing
- 2012-09-14 PL PL12832249T patent/PL2755980T3/pl unknown
- 2012-09-14 KR KR1020147009372A patent/KR20140061505A/ko active Search and Examination
- 2012-09-14 KR KR1020197027440A patent/KR102062323B1/ko active IP Right Grant
- 2012-09-14 CN CN201280044923.6A patent/CN103827124B/zh active Active
2014
- 2014-03-06 IL IL231391A patent/IL231391A/en active IP Right Grant
- 2014-04-11 CO CO14079711A patent/CO6930354A2/es unknown
- 2014-12-23 HK HK14112835.8A patent/HK1199262A1/xx unknown
2016
- 2016-12-22 JP JP2016248617A patent/JP6456907B2/ja active Active
2018
- 2018-10-26 JP JP2018201509A patent/JP2019038827A/ja active Pending

Also Published As

Publication number	Publication date
EP2755980A1 (en)	2014-07-23
CA2847858A1 (en)	2013-03-21
NZ622139A (en)	2015-05-29
KR20190112820A (ko)	2019-10-07
RU2607941C2 (ru)	2017-01-11
IL231391A (en)	2016-12-29
JP2019038827A (ja)	2019-03-14
RU2014114533A (ru)	2015-10-20
KR20140061505A (ko)	2014-05-21
JP2017095472A (ja)	2017-06-01
PL2755980T3 (pl)	2020-05-18
CN103827124A (zh)	2014-05-28
US20130066115A1 (en)	2013-03-14
CO6930354A2 (es)	2014-04-28
EP2755980B1 (en)	2019-10-30
JP6425543B2 (ja)	2018-11-21
MX2014003064A (es)	2014-05-07
US9145428B2 (en)	2015-09-29
CN103827124B (zh)	2017-06-06
EP2755980A4 (en)	2015-06-03
JP2014530193A (ja)	2014-11-17
IL231391A0 (en)	2014-04-30
KR102062323B1 (ko)	2020-01-03
WO2013040479A1 (en)	2013-03-21
HK1199262A1 (en)	2015-06-26
JP6456907B2 (ja)	2019-01-23

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BR112014001765A2 (pt)	2017-02-21	método
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DK3366358T3 (da)	2019-05-20	Bæresystem til brandsikringssprinkler
BR112014009795A2 (pt)	2017-04-25	método
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FI20115432A (fi)	2012-11-07	Rakennusjärjestelmä
FI9342U1 (fi)	2011-08-17	Jäähdytysjärjestelmä
FI9450U1 (fi)	2011-11-09	Hokkijärjestelmä
FI20115847A (fi)	2013-03-01	Navigointijärjestelmä ja -menetelmä
PL120242U1 (pl)	2013-02-04	System Duotank
DK2490191T3 (da)	2014-07-07	Holder til stopskilt