DK166355C - Adenosin-derivater samt farmaceutiske praeparater indeholdende saadanne derivater - Google Patents

Adenosin-derivater samt farmaceutiske praeparater indeholdende saadanne derivater

Info

Publication number: DK166355C
Authority: DK; Denmark
Prior art keywords: derivatives; adenosin; pharmaceutical preparations; preparations containing; pharmaceutical
Prior art date: 1987-08-26

Application number

DK475488A

Other languages

English (en)

Other versions

DK475488A (da

DK475488D0 (da

DK166355B (da

Inventor

Esa T Jarvi

James R Mccarthy

Nellikunja J Prakash

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-26

Filing date

1988-08-25

Publication date

1993-09-06

1988-08-25 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1988-08-25 Publication of DK475488D0 publication Critical patent/DK475488D0/da

1989-02-27 Publication of DK475488A publication Critical patent/DK475488A/da

1993-04-13 Publication of DK166355B publication Critical patent/DK166355B/da

1993-09-06 Application granted granted Critical

1993-09-06 Publication of DK166355C publication Critical patent/DK166355C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK475488A 1987-08-26 1988-08-25 Adenosin-derivater samt farmaceutiske praeparater indeholdende saadanne derivater DK166355C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8969387A	1987-08-26	1987-08-26
US8969387		1987-08-26

Publications (4)

Publication Number	Publication Date
DK475488D0 DK475488D0 (da)	1988-08-25
DK475488A DK475488A (da)	1989-02-27
DK166355B DK166355B (da)	1993-04-13
DK166355C true DK166355C (da)	1993-09-06

Family

ID=22219090

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK475488A DK166355C (da)	1987-08-26	1988-08-25	Adenosin-derivater samt farmaceutiske praeparater indeholdende saadanne derivater

Country Status (22)

Country	Link
US (1)	US4997924B1 (da)
EP (1)	EP0304889B1 (da)
JP (1)	JP2722215B2 (da)
KR (1)	KR970002660B1 (da)
CN (1)	CN1023561C (da)
AR (1)	AR244229A1 (da)
AT (1)	ATE141282T1 (da)
AU (1)	AU613660B2 (da)
CA (1)	CA1315779C (da)
DE (1)	DE3855470T2 (da)
DK (1)	DK166355C (da)
ES (1)	ES2092981T3 (da)
FI (1)	FI90876C (da)
GR (1)	GR3020849T3 (da)
HU (1)	HU199153B (da)
IE (1)	IE81117B1 (da)
IL (1)	IL87532A (da)
NO (1)	NO168361C (da)
NZ (1)	NZ225906A (da)
PH (1)	PH25533A (da)
PT (1)	PT88340B (da)
ZA (1)	ZA886216B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4996308A (en) *	1988-03-25	1991-02-26	Merrell Dow Pharmaceuticals Inc.	Derivatives with unsaturated substitutions for the 5'-hydroxymethyl group
HU204843B (en) *	1988-09-27	1992-02-28	Merrell Dow Pharma	Process for producing 2'-halogen-methylidene adenosine derivatives and pharmaceutical compositions comprising same
JPH02215781A (ja) *	1989-02-14	1990-08-28	Toyo Jozo Co Ltd	６’―デオキシ―６’―ハロゲノネプラノシンａおよびその製造法
JPH03118384A (ja) *	1989-07-24	1991-05-20	Glaxo Group Ltd	シクロペンタン誘導体
CA2027023C (en) *	1989-10-11	2001-12-25	Esa T. Jarvi	Inosine/guanosine derivatives
AU629988B2 (en) *	1989-10-11	1992-10-15	Merrell Dow Pharmaceuticals Inc.	Inosine/guanosine derivatives as antineoplastic agents
ZA908001B (en) *	1989-10-11	1991-08-28	Merrell Dow Pharma	Inosine/guanosine derivatives as immunosuppressive agents
DE4005275A1 (de) *	1990-02-20	1991-08-22	Grundmann Ewald	Verwendung von s-adenosylmethionin als mittel gegen virale infektionen durch retroviren
JPH0421682A (ja) *	1990-05-11	1992-01-24	Asahi Chem Ind Co Ltd	２―フルオロネプラノシンａおよびその製造法
US5618704A (en) *	1990-07-27	1997-04-08	Isis Pharmacueticals, Inc.	Backbone-modified oligonucleotide analogs and preparation thereof through radical coupling
ZA916350B (en) *	1990-08-16	1992-05-27	Merrell Dow Pharma	5'-vinylhalo-aristeromycin/adenosine analogs as immunosuppressants
US5244896A (en) *	1990-09-14	1993-09-14	Marion Merrell Dow Inc.	Carbocyclic adenosine analogs useful as immunosuppressants
US5514688A (en) *	1990-09-14	1996-05-07	Merrell Dow Pharmaceuticals Inc.	Carbocyclic adenosine analogs useful as immunosuppressants
US5206244A (en) *	1990-10-18	1993-04-27	E. R. Squibb & Sons, Inc.	Hydroxymethyl (methylenecyclopentyl) purines and pyrimidines
WO1994021659A1 (en) *	1993-03-18	1994-09-29	Yamasa Corporation	Novel 2'-methylidenenucleotide compound, process for producing the same, and pharmaceutical use thereof
EP0630897A3 (en) *	1993-06-25	1995-03-01	Bristol Myers Squibb Co	3-hydroxy-4-hydroxymethyl-2-methylene-cyclopentyl purines and pyrimidines.
US6579857B1 (en) *	1999-06-11	2003-06-17	Evanston Northwestern Healthcare Research Institute	Combination cancer therapy comprising adenosine and deaminase enzyme inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3928319A (en) *	1971-06-16	1975-12-23	Syntex Inc	4 -Fluoro nucleosides, novel intermediates and methods of preparing same
US3910885A (en) *	1974-03-12	1975-10-07	Syntex Inc	4-Alkoxy nucleosides and intermediates therefore
JPS5651414A (en) *	1979-10-02	1981-05-09	Toyo Jozo Co Ltd	Antibiotic substance neplanocin preparation
US4543255A (en) *	1984-05-10	1985-09-24	Southern Research Institute	Carbocyclic analogs of purine 2'-deoxyribofuranosides

1987
- 1987-08-23 NZ NZ225906A patent/NZ225906A/xx unknown
1988
- 1988-08-22 ZA ZA886216A patent/ZA886216B/xx unknown
- 1988-08-22 CA CA000575389A patent/CA1315779C/en not_active Expired - Fee Related
- 1988-08-23 IL IL87532A patent/IL87532A/xx not_active IP Right Cessation
- 1988-08-23 AR AR88311731A patent/AR244229A1/es active
- 1988-08-23 AU AU21438/88A patent/AU613660B2/en not_active Ceased
- 1988-08-23 FI FI883889A patent/FI90876C/fi not_active IP Right Cessation
- 1988-08-24 DE DE3855470T patent/DE3855470T2/de not_active Expired - Fee Related
- 1988-08-24 EP EP88113788A patent/EP0304889B1/en not_active Expired - Lifetime
- 1988-08-24 AT AT88113788T patent/ATE141282T1/de not_active IP Right Cessation
- 1988-08-24 ES ES88113788T patent/ES2092981T3/es not_active Expired - Lifetime
- 1988-08-25 DK DK475488A patent/DK166355C/da not_active IP Right Cessation
- 1988-08-25 CN CN88106240A patent/CN1023561C/zh not_active Expired - Fee Related
- 1988-08-25 NO NO883793A patent/NO168361C/no unknown
- 1988-08-25 PT PT88340A patent/PT88340B/pt not_active IP Right Cessation
- 1988-08-25 HU HU884455A patent/HU199153B/hu not_active IP Right Cessation
- 1988-08-25 KR KR88010802A patent/KR970002660B1/ko not_active IP Right Cessation
- 1988-08-25 IE IE259388A patent/IE81117B1/en not_active IP Right Cessation
- 1988-08-26 JP JP63210913A patent/JP2722215B2/ja not_active Expired - Fee Related
- 1988-08-26 PH PH37465A patent/PH25533A/en unknown
1989
- 1989-11-29 US US07445892 patent/US4997924B1/en not_active Expired - Lifetime
1996
- 1996-08-22 GR GR960402206T patent/GR3020849T3/el unknown

Also Published As

Publication number	Publication date
NO883793D0 (no)	1988-08-25
DK475488A (da)	1989-02-27
ES2092981T3 (es)	1996-12-16
IL87532A0 (en)	1989-01-31
US4997924A (en)	1991-03-05
AR244229A1 (es)	1993-10-29
EP0304889A2 (en)	1989-03-01
AU613660B2 (en)	1991-08-08
IE81117B1 (en)	2000-03-22
NO168361B (no)	1991-11-04
NO883793L (no)	1989-02-27
DK475488D0 (da)	1988-08-25
CN1023561C (zh)	1994-01-19
DE3855470T2 (de)	1997-03-13
GR3020849T3 (en)	1996-11-30
JPH01308267A (ja)	1989-12-12
NZ225906A (en)	1990-10-26
FI883889A (fi)	1989-02-27
DE3855470D1 (de)	1996-09-19
EP0304889A3 (en)	1990-01-24
EP0304889B1 (en)	1996-08-14
IL87532A (en)	1993-05-13
KR970002660B1 (en)	1997-03-07
HU199153B (en)	1990-01-29
NO168361C (no)	1992-02-12
AU2143888A (en)	1989-03-02
KR890003796A (ko)	1989-04-18
IE882593L (en)	1989-02-26
JP2722215B2 (ja)	1998-03-04
PH25533A (en)	1991-07-24
CN1033632A (zh)	1989-07-05
CA1315779C (en)	1993-04-06
PT88340B (pt)	1995-05-04
FI90876C (fi)	1994-04-11
DK166355B (da)	1993-04-13
FI90876B (fi)	1993-12-31
US4997924B1 (en)	1995-11-14
ZA886216B (en)	1989-04-26
PT88340A (pt)	1989-06-30
FI883889A0 (fi)	1988-08-23
HUT47954A (en)	1989-04-28
ATE141282T1 (de)	1996-08-15

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Legal Events

Date	Code	Title	Description
2004-08-23	PBP	Patent lapsed	Country of ref document: DK