DK160269C - METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AROYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONER OR A PHARMACEUTICAL ACCEPTABLE METAL SALT OR BASIC AMMONIUM SALT THEREOF - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AROYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONER OR A PHARMACEUTICAL ACCEPTABLE METAL SALT OR BASIC AMMONIUM SALT THEREOF

Info

Publication number: DK160269C
Authority: DK; Denmark
Prior art keywords: oner; aroyl; imidazol; dihydro; analogue
Prior art date: 1979-06-18

Application number

DK259080A

Other languages

Danish (da)

Other versions

DK160269B (en

DK259080A (en

Inventor

Richard A Schnettler

Richard C Dage

J Martin Grisar

Original Assignee

Richardson Merrell Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-06-18

Filing date

1980-06-17

Publication date

1991-07-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK160269(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1980-06-17 Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc

1980-12-19 Publication of DK259080A publication Critical patent/DK259080A/en

1991-02-18 Publication of DK160269B publication Critical patent/DK160269B/en

1991-07-22 Application granted granted Critical

1991-07-22 Publication of DK160269C publication Critical patent/DK160269C/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK259080A 1979-06-18 1980-06-17 METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AROYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONER OR A PHARMACEUTICAL ACCEPTABLE METAL SALT OR BASIC AMMONIUM SALT THEREOF DK160269C (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US4980879A	1979-06-18	1979-06-18
US4980879		1979-06-18
US11920780A	1980-02-07	1980-02-07
US11920780		1980-02-07

Publications (3)

Publication Number	Publication Date
DK259080A DK259080A (en)	1980-12-19
DK160269B DK160269B (en)	1991-02-18
DK160269C true DK160269C (en)	1991-07-22

Family

ID=26727558

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK259080A DK160269C (en)	1979-06-18	1980-06-17	METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AROYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONER OR A PHARMACEUTICAL ACCEPTABLE METAL SALT OR BASIC AMMONIUM SALT THEREOF

Country Status (20)

Country	Link
AT (1)	AT375349B (en)
AU (1)	AU532783B2 (en)
CA (1)	CA1132554A (en)
CH (1)	CH646155A5 (en)
DE (1)	DE3021792A1 (en)
DK (1)	DK160269C (en)
ES (1)	ES8105299A1 (en)
FR (1)	FR2459233A1 (en)
GB (1)	GB2055364B (en)
HK (1)	HK61486A (en)
HU (1)	HU186736B (en)
IE (1)	IE50646B1 (en)
IL (1)	IL60243A (en)
IT (1)	IT1143922B (en)
MY (1)	MY8600709A (en)
NL (2)	NL193752C (en)
NO (1)	NO152841C (en)
NZ (1)	NZ193935A (en)
PH (1)	PH18683A (en)
SE (2)	SE447107B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH18106A (en) *	1981-02-18	1985-03-21	Merrell Dow Pharma	Novel-4-aroylimidazol-2-ones
US4405628A (en) *	1981-03-05	1983-09-20	Merrell Dow Pharmaceuticals Inc.	4-Pyridylimidazolones and method of use
JPS57185266A (en) *	1981-05-04	1982-11-15	Merrell Dow Pharma	4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazole- 2-one
US4371737A (en) *	1981-05-04	1983-02-01	Merrell Dow Pharmaceuticals Inc.	5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4526981A (en) *	1981-05-04	1985-07-02	Merrell Dow Pharmaceuticals Inc.	[1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
US4329471A (en) *	1981-05-04	1982-05-11	Merrell Dow Pharmaceuticals Inc.	4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4329470A (en) *	1981-05-04	1982-05-11	Merrell Dow Pharmaceuticals Inc.	5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4381393A (en) *	1981-05-04	1983-04-26	Merrell Dow Pharmaceuticals Inc.	4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4410540A (en) *	1981-11-04	1983-10-18	Merrell Dow Pharmaceuticals Inc.	Cardiotonic 4-aroylimidazolidin-2-ones
US4367236A (en)	1981-11-04	1983-01-04	Merrell Dow Pharmaceuticals Inc.	Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
EP1737447A1 (en) *	2004-03-22	2007-01-03	Myogen, Inc.	(r)-enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
US20060025463A1 (en) *	2004-03-22	2006-02-02	Michael Bristow	Enoximone sulfoxide enantiomers and their use in the treatment of PDE-III mediated diseases
US20070225217A1 (en)	2005-11-09	2007-09-27	Combinatorx, Incorporated	Methods, compositions, and kits for the treatment of medical conditions
ES2559319T3 (en)	2007-06-04	2016-02-11	Synergy Pharmaceuticals Inc.	Guanylate cliclas agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP2011522828A (en)	2008-06-04	2011-08-04	シナジーファーマシューティカルズインコーポレイテッド	Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer, and other disorders
WO2010009319A2 (en)	2008-07-16	2010-01-21	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
WO2012118972A2 (en)	2011-03-01	2012-09-07	Synegy Pharmaceuticals Inc.	Process of preparing guanylate cyclase c agonists
US20150119399A1 (en)	2012-01-10	2015-04-30	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
US9545446B2 (en)	2013-02-25	2017-01-17	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase and their uses
US9708367B2 (en)	2013-03-15	2017-07-18	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase and their uses
EP2968439A2 (en)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
PT3004138T (en)	2013-06-05	2024-06-18	Bausch Health Ireland Ltd	Ultra-pure agonists of guanylate cyclase c, method of making and using same
IL280864B2 (en)	2013-08-09	2024-03-01	Ardelyx Inc	Compounds and methods for inhibiting phosphate transport
EP3972599A1 (en)	2019-05-21	2022-03-30	Ardelyx, Inc.	Combination for lowering serum phosphate in a patient
CN114539157B (en) *	2022-03-03	2023-12-22	曲靖师范学院	Method for preparing 4-iodo-N-aryl pyrazole compound by iodine-promoted oxidation method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2441933A (en) *	1945-07-30	1948-05-18	Hoffmann La Roche	Substituted imidazolones and process of making them

1980
- 1980-06-04 NZ NZ193935A patent/NZ193935A/en unknown
- 1980-06-05 IE IE1162/80A patent/IE50646B1/en not_active IP Right Cessation
- 1980-06-06 IL IL60243A patent/IL60243A/en unknown
- 1980-06-06 AU AU59118/80A patent/AU532783B2/en not_active Expired
- 1980-06-06 SE SE8004253A patent/SE447107B/en not_active IP Right Cessation
- 1980-06-09 ES ES492255A patent/ES8105299A1/en not_active Expired
- 1980-06-11 DE DE19803021792 patent/DE3021792A1/en active Granted
- 1980-06-13 AT AT0314280A patent/AT375349B/en not_active IP Right Cessation
- 1980-06-16 PH PH24143A patent/PH18683A/en unknown
- 1980-06-16 CH CH462780A patent/CH646155A5/en not_active IP Right Cessation
- 1980-06-17 IT IT48997/80A patent/IT1143922B/en active Protection Beyond IP Right Term
- 1980-06-17 HU HU801506A patent/HU186736B/en unknown
- 1980-06-17 NO NO801796A patent/NO152841C/en unknown
- 1980-06-17 CA CA354,197A patent/CA1132554A/en not_active Expired
- 1980-06-17 FR FR8013434A patent/FR2459233A1/en active Granted
- 1980-06-17 NL NL8003498A patent/NL193752C/en not_active IP Right Cessation
- 1980-06-17 DK DK259080A patent/DK160269C/en not_active IP Right Cessation
- 1980-06-18 GB GB8019898A patent/GB2055364B/en not_active Expired
1985
- 1985-03-25 SE SE8501452A patent/SE464559B/en not_active IP Right Cessation
1986
- 1986-08-21 HK HK614/86A patent/HK61486A/en not_active IP Right Cessation
- 1986-12-30 MY MY709/86A patent/MY8600709A/en unknown
2000
- 2000-09-04 NL NL300015C patent/NL300015I1/en unknown

Also Published As

Publication number	Publication date
FR2459233B1 (en)	1983-09-23
DK160269B (en)	1991-02-18
AU532783B2 (en)	1983-10-13
ES492255A0 (en)	1981-06-01
IL60243A0 (en)	1980-09-16
NL193752C (en)	2000-09-04
ATA314280A (en)	1983-12-15
MY8600709A (en)	1986-12-31
FR2459233A1 (en)	1981-01-09
SE464559B (en)	1991-05-13
GB2055364B (en)	1983-06-08
NL193752B (en)	2000-05-01
IL60243A (en)	1987-01-30
HK61486A (en)	1986-08-29
NZ193935A (en)	1985-05-31
SE447107B (en)	1986-10-27
IT1143922B (en)	1986-10-29
IT8048997A0 (en)	1980-06-17
DK259080A (en)	1980-12-19
IE50646B1 (en)	1986-06-11
DE3021792A1 (en)	1981-01-22
SE8501452L (en)	1985-03-25
NL300015I1 (en)	2000-11-01
NO152841B (en)	1985-08-19
NL300015I2 (en)	2000-10-02
GB2055364A (en)	1981-03-04
IE801162L (en)	1980-12-18
AT375349B (en)	1984-07-25
SE8004253L (en)	1980-12-19
NL8003498A (en)	1980-12-22
AU5911880A (en)	1981-01-08
NO801796L (en)	1980-12-19
ES8105299A1 (en)	1981-06-01
CA1132554A (en)	1982-09-28
HU186736B (en)	1985-09-30
NO152841C (en)	1985-11-27
DE3021792C2 (en)	1989-08-10
CH646155A5 (en)	1984-11-15
PH18683A (en)	1985-08-29
SE8501452D0 (en)	1985-03-25

Similar Documents

Publication	Publication Date	Title
DK160269C (en)	1991-07-22	METHOD OF ANALOGUE FOR THE PREPARATION OF 4-AROYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONER OR A PHARMACEUTICAL ACCEPTABLE METAL SALT OR BASIC AMMONIUM SALT THEREOF
DK149308C (en)	1986-12-08	METHOD OF ANALOGUE FOR THE PREPARATION OF TRANS-4-PHENYL-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE DERIVATIVES OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS.
DK151884C (en)	1988-06-13	METHOD OF ANALOGUE FOR THE PREPARATION OF 3- (1-IMIDAZOLYLALKYL) INCIDENTAL OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS THEREOF
DK155048C (en)	1989-06-26	METHOD OF ANALOGUE FOR PREPARING 1,8-NAPHTHYRIDE COMPOUNDS
DK156001C (en)	1989-11-06	METHOD OF ANALOGUE FOR THE PREPARATION OF MERCAPTOS-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES
DK156825C (en)	1990-03-12	ANALOGUE PROCEDURE FOR PREPARING A BASIC ETHER OR A PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALT OR QUATERNARY SALT THEREOF
DK152114C (en)	1988-06-20	METHOD OF ANALOGUE FOR THE PREPARATION OF PROPENYLAMINES OR PHARMACEUTICAL ACCEPTABLE SALTS THEREOF
DK148904C (en)	1986-04-14	METHOD OF ANALOGUE FOR THE PREPARATION OF ANALGETICALLY EFFECTIVE ENKEPHALIN ANALOGUE PENTAPEPTIDAMIDES OR PHARMACEUTICAL ACCEPTABLE NON-TOXIC ACID ADDITION SALTS THEREOF
DK160045C (en)	1991-06-10	METHOD OF ANALOGUE FOR THE PREPARATION OF 4-OXO-4H-PYRIDOOE1,2-AAAPYRIMIDINES OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS OR QUATERNARY AMMONIUM SALTS THEREOF
DK149846C (en)	1987-06-29	METHOD OF ANALOGUE FOR THE PREPARATION OF N, N'-BIS-TETRAHYDRO-ISOQUINOLYLD DISULPHONYLIMIDES
DK157862C (en)	1990-08-06	METHOD OF ANALOGUE FOR THE PREPARATION OF IMIDAZOLYLPHENYLAMIDINES OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS
DK159119C (en)	1991-03-11	METHOD OF ANALOGUE FOR THE PREPARATION OF ACID ADDITION SALTS OF 3ALFA-ACYLOXY-2BETA, 16BETA-DIPIPERIDINO-5ALFA ANDROSTAND DERIVATIVES, AND PROCEDURES FOR THE PREPARATION OF PHARMACEUTICAL PRODUCTS
DK158658C (en)	1990-12-31	METHOD OF ANALOGUE FOR THE PREPARATION OF 9-AMINOAL COOLFluorens OR PHARMACEUTICAL ACCEPTABLE SALTS THEREOF
DK146281C (en)	1984-01-30	METHOD OF ANALOGUE FOR THE PREPARATION OF 2-BROMO-6-FLUORO-N-2-IMIDAZOLIDINYLIDE-BENZAMINE OR ACID ADDITION SALTS.
DK151805C (en)	1988-06-13	METHOD OF ANALOGUE FOR THE PREPARATION OF 20,21-DI-NOR-EBURNAMENIN DERIVATIVES OR PHARMACEUTICAL ACCEPTABLE ADDITIONAL SALTS THEREOF
DK149611C (en)	1987-01-26	METHOD OF ANALOGUE FOR THE PREPARATION OF TRH-ANALOGUE TRIPEPTIDAMIDES OR THERAPEUTICALLY ACCEPTABLE COMPLEXES OR SALTS THEREOF
DK145263C (en)	1983-03-07	METHOD OF ANALOGUE FOR THE PREPARATION OF IMIDAZOTHIAZINES OR PHARMACEUTICAL ACCEPTABLE SALTS THEREOF
DK152677C (en)	1988-10-24	METHOD OF ANALOGUE FOR THE PREPARATION OF 4'-O-TETRA-HYDROPYRANYLADRIAMYCINE OR A POISONOUS ACID ADDITION SALT
DK149625C (en)	1987-01-26	METHOD OF ANALOGUE FOR THE PREPARATION OF N-SUBSTITUTED (8-HALOGEN OR TRIFLUORMETHYL-4-QUINOLYLAMINO) -BENZAMIDES OR A PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALT
DK152427C (en)	1988-07-25	METHOD OF ANALOGUE FOR THE PREPARATION OF 4-THIOMETHYLPYRIDINE COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS THEREOF
DK150197C (en)	1987-11-02	METHOD OF ANALOGUE FOR THE PREPARATION OF 2-SUBSTITUTED 1-AMINOAL COXIMINO CYCLOALKANES OR AN ACID ADDITION SALT OR QUATERNATE AMMONIUM DERIVATIVE THEREOF
DK148903C (en)	1986-04-14	METHOD OF ANALOGUE FOR THE PREPARATION OF ENKEPHALIN ANALOGUE PENTAPEPTIDE DERIVATIVES OR ACID ADDITION SALTS.
DK152491C (en)	1988-07-25	METHOD OF ANALOGUE FOR THE PREPARATION OF ESTERENTIC PHENOXYPROPANOLAMINES OR PHARMACEUTICAL APPLICABLE SALTS THEREOF
DK157021C (en)	1990-04-02	METHOD OF ANALOGUE FOR THE PREPARATION OF 2,3-POLYMETHYLENE-4-OXO-4H-PYRIDO- OR -AZEPINOOE1,2-AAAPYRIMIDINES OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS OR QUATERA SALTS
DK160875C (en)	1991-10-14	METHOD OF ANALOGUE FOR THE PREPARATION OF 3,7-DIAZABICYCLOOE3.3.1AA-NONANEOUS OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS

Legal Events

Date	Code	Title	Description
2000-07-10	PUP	Patent expired