DK123357B - Analogifremgangsmåde til fremstilling af N(6)-benzyl-adenosin-derivater. - Google Patents

Analogifremgangsmåde til fremstilling af N(6)-benzyl-adenosin-derivater.

Info

Publication number: DK123357B
Authority: DK; Denmark
Prior art keywords: benzyl; preparation; analogous process; adenosine derivatives; adenosine
Prior art date: 1970-02-18

Application number

DK69471AA

Other languages

English (en)

Inventor

W Juhran

M Thiel

K Dietmann

W Kampe

E Fauland

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-02-18

Filing date

1971-02-16

Publication date

1972-06-12

1971-02-16 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1972-06-12 Publication of DK123357B publication Critical patent/DK123357B/da

Links

MRPKNNSABYPGBF-LSCFUAHRSA-N (2r,3r,4s,5r)-2-[6-(benzylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol Chemical class O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(NCC=3C=CC=CC=3)=C2N=C1 MRPKNNSABYPGBF-LSCFUAHRSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK69471AA 1970-02-18 1971-02-16 Analogifremgangsmåde til fremstilling af N(6)-benzyl-adenosin-derivater. DK123357B (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19702007273 DE2007273A1 (de)	1970-02-18	1970-02-18	N(6) Aralkyl adenosin Derivate und Verfahren zur Herstellung derselben

Publications (1)

Publication Number	Publication Date
DK123357B true DK123357B (da)	1972-06-12

Family

ID=5762543

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK69471AA DK123357B (da)	1970-02-18	1971-02-16	Analogifremgangsmåde til fremstilling af N(6)-benzyl-adenosin-derivater.

Country Status (14)

Country	Link
US (1)	US3781273A (da)
JP (1)	JPS5116440B1 (da)
AT (2)	AT306251B (da)
CA (1)	CA953714A (da)
CH (2)	CH549600A (da)
DE (1)	DE2007273A1 (da)
DK (1)	DK123357B (da)
ES (1)	ES388194A1 (da)
FR (1)	FR2081524B1 (da)
GB (1)	GB1279946A (da)
HU (1)	HU162739B (da)
IL (1)	IL36211A0 (da)
NL (1)	NL7102026A (da)
ZA (1)	ZA711030B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0300144A3 (en) *	1984-04-18	1989-09-27	Whitby Research Incorporated	N-6 alkyl substituted adenosine derivatives as cardiac vasodilators
US5310731A (en) *	1984-06-28	1994-05-10	Whitby Research, Inc.	N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
AU8276187A (en) *	1986-10-31	1988-05-25	Warner-Lambert Company	Selected n6-substituted adenosines having selective a2 binding activity
US5066655A (en) *	1987-04-24	1991-11-19	Whitby Research, Inc.	N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5565566A (en) *	1987-04-24	1996-10-15	Discovery Therapeutics, Inc.	N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5070877A (en) *	1988-08-11	1991-12-10	Medco Research, Inc.	Novel method of myocardial imaging
US5032584A (en) *	1988-10-26	1991-07-16	G. D. Searle & Co.	S-diastereomer of an n6 -((2-hydroxypropyl)aryl)adenosine and its medicinal uses
US5030624A (en) *	1988-10-26	1991-07-09	G. D. Searle & Co.	R-diastereomer of an N6 -[(2-hydroxypropyl)aryl]adenosine and its medicinal uses
US6784165B1 (en) *	1999-11-23	2004-08-31	Aderis Pharmaceuticals, Inc.	Treatment of heart rhythm disturbances with N6-substituted-5′-(N-substituted) carboxamidoadenosines
CZ294538B6 (cs) *	2002-12-30	2005-01-12	Ústav Experimentální Botaniky Akademie Vědčeské Re	Substituční deriváty N6-benzyladenosinu, způsob jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
US20050009776A1 (en) *	2003-04-24	2005-01-13	Aderis Pharmaceuticals, Inc.	Method of treating atrial fibrillation or atrial flutter
US20050118262A1 (en) *	2003-09-17	2005-06-02	Jack Aurora	Controlled release formulation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2881164A (en) *	1955-07-18	1959-04-07	American Cyanamid Co	Ribofuranosyl derivatives of 6-aralkylamino and 6-heterocyclicalkylaminopurines
US3506643A (en) *	1966-12-09	1970-04-14	Max Thiel	N**6-aralkyl-adenosine derivatives

1970
- 1970-02-18 DE DE19702007273 patent/DE2007273A1/de active Pending
1971
- 1971-02-03 US US00112424A patent/US3781273A/en not_active Expired - Lifetime
- 1971-02-12 ES ES388194A patent/ES388194A1/es not_active Expired
- 1971-02-16 DK DK69471AA patent/DK123357B/da unknown
- 1971-02-16 CH CH284974A patent/CH549600A/xx not_active IP Right Cessation
- 1971-02-16 HU HUBO1274A patent/HU162739B/hu unknown
- 1971-02-16 NL NL7102026A patent/NL7102026A/xx not_active Application Discontinuation
- 1971-02-16 CA CA105,563A patent/CA953714A/en not_active Expired
- 1971-02-16 IL IL36211A patent/IL36211A0/xx unknown
- 1971-02-16 CH CH220871A patent/CH549596A/xx not_active IP Right Cessation
- 1971-02-17 AT AT137871A patent/AT306251B/de not_active IP Right Cessation
- 1971-02-17 AT AT123372A patent/AT313483B/de active
- 1971-02-17 ZA ZA711030A patent/ZA711030B/xx unknown
- 1971-02-17 FR FR7105318A patent/FR2081524B1/fr not_active Expired
- 1971-02-18 JP JP46007691A patent/JPS5116440B1/ja active Pending
- 1971-04-19 GB GB21877/71A patent/GB1279946A/en not_active Expired

Also Published As

Publication number	Publication date
AT313483B (de)	1974-02-25
FR2081524B1 (da)	1974-09-27
JPS5116440B1 (da)	1976-05-24
DE2007273A1 (de)	1971-08-26
AT306251B (de)	1973-04-10
ES388194A1 (es)	1973-05-01
CH549596A (de)	1974-05-31
CH549600A (de)	1974-05-31
ZA711030B (en)	1971-11-24
SU399134A3 (da)	1973-09-27
GB1279946A (en)	1972-06-28
IL36211A0 (en)	1971-04-28
US3781273A (en)	1973-12-25
CA953714A (en)	1974-08-27
HU162739B (da)	1973-04-28
FR2081524A1 (da)	1971-12-03
NL7102026A (da)	1971-08-20

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