DK0750672T3 - DNA-sekvenser for matrix-metalproteaser, deres tilvejebringelse og anvendelse - Google Patents

DNA-sekvenser for matrix-metalproteaser, deres tilvejebringelse og anvendelse

Info

Publication number
DK0750672T3
DK0750672T3 DK95915743T DK95915743T DK0750672T3 DK 0750672 T3 DK0750672 T3 DK 0750672T3 DK 95915743 T DK95915743 T DK 95915743T DK 95915743 T DK95915743 T DK 95915743T DK 0750672 T3 DK0750672 T3 DK 0750672T3
Authority
DK
Denmark
Prior art keywords
dna sequences
generation
matrix metal
metal proteases
disclosed
Prior art date
Application number
DK95915743T
Other languages
English (en)
Inventor
Horst Will
Bernd Hinzmann
Original Assignee
Max Delbrueck Centrum
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4438838A external-priority patent/DE4438838C1/de
Application filed by Max Delbrueck Centrum filed Critical Max Delbrueck Centrum
Application granted granted Critical
Publication of DK0750672T3 publication Critical patent/DK0750672T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK95915743T 1994-03-17 1995-03-17 DNA-sekvenser for matrix-metalproteaser, deres tilvejebringelse og anvendelse DK0750672T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4409663 1994-03-17
DE4438838A DE4438838C1 (de) 1994-03-17 1994-10-21 DNA-Sequenzen für Matrix-Metallproteasen, ihre Herstellung und ihre Verwendung
PCT/DE1995/000357 WO1995025171A2 (de) 1994-03-17 1995-03-17 Dna-sequenzen für matrix-metallproteasen, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
DK0750672T3 true DK0750672T3 (da) 2002-03-18

Family

ID=25934916

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95915743T DK0750672T3 (da) 1994-03-17 1995-03-17 DNA-sekvenser for matrix-metalproteaser, deres tilvejebringelse og anvendelse

Country Status (8)

Country Link
US (2) US6114159A (da)
EP (1) EP0750672B1 (da)
JP (1) JP3802560B2 (da)
AT (1) ATE209684T1 (da)
DK (1) DK0750672T3 (da)
ES (1) ES2168361T3 (da)
PT (1) PT750672E (da)
WO (1) WO1995025171A2 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6825024B1 (en) 1993-11-30 2004-11-30 Fuji Yakuhin Kogyo Kabushiki Kaisha Metalloproteinase and encoding DNA therefor
JPH07303482A (ja) 1993-11-30 1995-11-21 Fuji Yakuhin Kogyo Kk 新規なメタロプロテアーゼおよびそれをコードするｄｎａ
WO1997004080A1 (fr) * 1995-07-14 1997-02-06 Fuji Yakuhin Kogyo Kabushiki Kaisha Nouvelle proteine et anticorps monoclonal specifique a cette derniere
DE19543265A1 (de) * 1995-11-20 1997-06-05 Univ Konstanz Autoantigene und Verfahren zur Diagnose von Autoimmunkrankheiten
JPH1080283A (ja) * 1996-04-25 1998-03-31 Takeda Chem Ind Ltd 新規タンパク質およびそのｄｎａ
WO1998040475A1 (en) 1997-03-11 1998-09-17 Abbott Laboratories Human matrix metalloprotease gene, proteins encoded therefrom and methods of using same
US6271014B1 (en) 1998-01-09 2001-08-07 Schering-Plough Mammalian proteinases; related reagents and methods
WO2000018900A1 (fr) * 1998-09-29 2000-04-06 Motoji Seiki Adn codant pour de nouveaux polypeptides
WO2001026671A1 (en) * 1999-10-12 2001-04-19 Smithkline Beecham Corporation Methods of treatment using dual matrix-metalloproteinase-2 and matrix metalloproteinase-9 inhibitors
WO2001088131A1 (fr) * 2000-05-19 2001-11-22 Fujichemico, Ltd. Regulation de l'activite de mt1-mmp
MXPA04010092A (es) * 2002-04-16 2004-12-13 Genentech Inc Composiciones y metodos para el diagnostico y tratamiento de tumores.
US20070128685A1 (en) * 2005-07-01 2007-06-07 Rodolfo Faudoa Methods and compositions for cell culture
US20070004036A1 (en) * 2005-07-01 2007-01-04 Rodolfo Faudoa Methods and compositions for keratinocyte culture
US20070003541A1 (en) * 2005-07-01 2007-01-04 Rodolfo Faudoa Methods and compositions for therapeutics
ITFI20050178A1 (it) * 2005-08-12 2007-02-13 Protera S R L Uso di metalloproteinasi di matrice, mutate e non, per la preparazione di composizioni farmaceutiche, e metalloproteinasi mutate aventi aumentata stabilita'
JP2009522302A (ja) * 2005-12-30 2009-06-11 ダイアックス コーポレーション マトリックスメタロプロテイナーゼ結合タンパク質
WO2008043309A1 (en) * 2006-09-29 2008-04-17 Accelergy Shanghai R & D Center Co., Ltd. Process and system of preparing ultra pure ionic liquids
US8147836B2 (en) 2007-12-17 2012-04-03 Dyax Corp. Compositions and methods for treating osteolytic disorders comprising MMP-14 binding proteins
TWI395593B (zh) 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
WO2010102262A1 (en) * 2009-03-06 2010-09-10 Halozyme, Inc. Temperature sensitive mutants of matrix metalloprotease 1 und uses thereof
US20130012451A1 (en) * 2009-12-21 2013-01-10 The Research Foundation Of State University Of New York Compositions and methods for inhibiting mmp-9-mediated cell migration
US10314909B2 (en) 2011-10-21 2019-06-11 Dyax Corp. Combination therapy comprising an MMP-14 binding protein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995015374A1 (fr) * 1993-11-30 1995-06-08 Fuji Yakuhin Kogyo Kabushiki Kaisha Nouvelle metalloprotease et adn codant pour cette derniere
US5652127A (en) * 1995-06-02 1997-07-29 Genencor International, Inc. Method for liquefying starch

Also Published As

Publication number Publication date
PT750672E (pt) 2002-05-31
EP0750672B1 (de) 2001-11-28
JPH10501962A (ja) 1998-02-24
US6399348B1 (en) 2002-06-04
ES2168361T3 (es) 2002-06-16
JP3802560B2 (ja) 2006-07-26
WO1995025171A3 (de) 1996-02-22
WO1995025171A2 (de) 1995-09-21
ATE209684T1 (de) 2001-12-15
EP0750672A1 (de) 1997-01-02
US6114159A (en) 2000-09-05

Similar Documents

Publication Publication Date Title
DK0750672T3 (da) DNA-sekvenser for matrix-metalproteaser, deres tilvejebringelse og anvendelse
DE69738581D1 (de) Menschliche dnase i hyperaktive varianten
MXPA02011656A (es) Moleculas de acido nucleico nrg-2, polipeptidos, y metodos de diagnostico y terapeuticos.
MX344216B (es) Productos geneticos expresados de forma diferencial en tumores y su uso.
BR9814276A (pt) Antìgenos de superfìcie
DE3856180D1 (de) Nukleinsaürefragmente, die mannose bindende fragmente vom menschlichen mannosebindenden protein kodieren
ATE354638T1 (de) Menschlicher gewebsinhibitor von metalloproteinase-4
NO20110429L (no) Polypeptider og nukleinsyre-DNA for anvendelse innen medisin
PT84089A (en) Dna sequences coding for proteins having the biological activity of husi-type i inhibitors biotechnological methods for the preparation of said proteins and pharmaceutical compositions containing said proteins
EP1100815A4 (en) PROTEASE TYPE II CLEAVABLE PEPTIDE
DE50212280D1 (de) Verwendung von hmgb-proteinen und dafür codierenden nukleinsäuren
GEP20043386B (en) β -Amyloid Peptide-Binding Proteins and Polynucleotides Encoding the Same
ATE311456T1 (de) Nucleinsäure-moleküle codierend proteine, die die adhäsion von neisseria-zellen an humane zellen vermitteln
MX9805158A (es) Adn que codifica una proteina activadora de plasminogeno.
ATE278011T1 (de) Human dnase ii
WO2002000878A3 (fr) Dynamine mitochondriale humaine msp1, ses isoformes msp1-x, et leur utilisation en therapeutique
FR2813606B1 (fr) Proteine bard1 tronquee, et ses applications diagnostiques et therapeutiques
DE69027967D1 (de) Proteine, die die expression von vertebraten-mhc-klasse-ii-genen regulieren, dafür kodierende dna-sequenzen und pharmazeutische zusammensetzungen
DE69529235D1 (de) Menschliche dnase i varianten
DE69033553D1 (de) Rekombinante herstellung von laktoperoxidase
ATE323772T1 (de) Regulatorische sequenzen des humanen mcp-1 gens
AU2002350406A1 (en) Identification of ses-3 (spr-5) in c. elegans and the uses of the same
AU2002314193A1 (en) Identification of ses-1 and the uses of the same
MX9709390A (es) Cistatina e humana.