DK0461012T3 - Derivater af ((1-arylpyrrolidin-2-yl)methyl)piperazin, fremstillingen heraf og deres terapeutiske anvendelse - Google Patents

Derivater af ((1-arylpyrrolidin-2-yl)methyl)piperazin, fremstillingen heraf og deres terapeutiske anvendelse

Info

Publication number
DK0461012T3
DK0461012T3 DK91401431.1T DK91401431T DK0461012T3 DK 0461012 T3 DK0461012 T3 DK 0461012T3 DK 91401431 T DK91401431 T DK 91401431T DK 0461012 T3 DK0461012 T3 DK 0461012T3
Authority
DK
Denmark
Prior art keywords
group
denotes
formula
arylpyrrolidin
methyl
Prior art date
Application number
DK91401431.1T
Other languages
English (en)
Inventor
Pascal George
Daniel Obitz
Dennis Bigg
Jacques Menin
Jean-Pierre Merly
Michel Peynot
Corinne Veronique
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Application granted granted Critical
Publication of DK0461012T3 publication Critical patent/DK0461012T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK91401431.1T 1990-06-07 1991-06-03 Derivater af ((1-arylpyrrolidin-2-yl)methyl)piperazin, fremstillingen heraf og deres terapeutiske anvendelse DK0461012T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9007067A FR2663026B1 (fr) 1990-06-07 1990-06-07 Derives de [(1-arylpyrrolidin-2-yl) methyl] piperazine, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
DK0461012T3 true DK0461012T3 (da) 1994-09-12

Family

ID=9397358

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91401431.1T DK0461012T3 (da) 1990-06-07 1991-06-03 Derivater af ((1-arylpyrrolidin-2-yl)methyl)piperazin, fremstillingen heraf og deres terapeutiske anvendelse

Country Status (21)

Country Link
US (1) US5192763A (da)
EP (1) EP0461012B1 (da)
JP (1) JPH04235958A (da)
KR (1) KR100188902B1 (da)
AT (1) ATE104662T1 (da)
AU (1) AU634391B2 (da)
CA (1) CA2043981A1 (da)
CS (1) CS173691A3 (da)
DE (1) DE69101740T2 (da)
DK (1) DK0461012T3 (da)
ES (1) ES2054460T3 (da)
FI (1) FI97055C (da)
FR (1) FR2663026B1 (da)
HU (1) HU209620B (da)
IE (1) IE64688B1 (da)
IL (1) IL98372A (da)
NO (1) NO177931C (da)
NZ (1) NZ238431A (da)
PL (1) PL165187B1 (da)
PT (1) PT97885B (da)
ZA (1) ZA914339B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1245712B (it) * 1991-04-09 1994-10-14 Boehringer Mannheim Italia Ammine eterocicliche utili terapia dell'asma e dell'infiammazione delle vie aeree
FR2684374B1 (fr) * 1991-12-02 1995-05-19 Synthelabo Derives substitues de 1-[(1-arylpyrrolidin-2-yl)methyl]piperazine, leur preparation et leur application en therapeutique.
IT1255704B (it) * 1992-09-30 1995-11-10 Boehringer Mannheim Italia Ammine eterocicliche utili nella terapia dell'asma e dell'infiammazione delle vie aeree

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3250771A (en) * 1962-12-17 1966-05-10 Geigy Chem Corp 5-monocarbocyclic aryl-n-lower alkyl-2-pyrrolidine carboxylic acid, esters, amides and derivatives thereof
GB1428493A (en) * 1973-05-02 1976-03-17 Science Union & Cie Heterocyclic amides processes for their preparation and pharma ceutical compositions containing them
US5063242A (en) * 1989-04-21 1991-11-05 Warner-Lambert Company 7-((substituted)amino)-8-((substituted)carbonyl)-methylamino-1-oxaspiro[4,5]decanes as diuretics antiinflammatory, and cerebrovascular agents

Also Published As

Publication number Publication date
PL290572A1 (en) 1992-02-10
FR2663026B1 (fr) 1992-08-07
IE64688B1 (en) 1995-08-23
US5192763A (en) 1993-03-09
IE911941A1 (en) 1991-12-18
FI97055C (fi) 1996-10-10
HU911895D0 (en) 1991-12-30
HU209620B (en) 1994-09-28
NZ238431A (en) 1992-09-25
HUT58070A (en) 1992-01-28
NO912168L (no) 1991-12-09
AU7819691A (en) 1991-12-12
DE69101740D1 (de) 1994-05-26
IL98372A0 (en) 1992-07-15
NO912168D0 (no) 1991-06-06
ATE104662T1 (de) 1994-05-15
PL165187B1 (pl) 1994-11-30
EP0461012A1 (fr) 1991-12-11
EP0461012B1 (fr) 1994-04-20
IL98372A (en) 1996-01-31
ZA914339B (en) 1992-03-25
NO177931C (no) 1995-12-20
FI912733A (fi) 1991-12-08
KR100188902B1 (ko) 1999-06-01
ES2054460T3 (es) 1994-08-01
CA2043981A1 (en) 1991-12-08
FR2663026A1 (fr) 1991-12-13
NO177931B (no) 1995-09-11
CS173691A3 (en) 1992-02-19
FI912733A0 (fi) 1991-06-06
JPH04235958A (ja) 1992-08-25
PT97885A (pt) 1992-03-31
PT97885B (pt) 1998-10-30
KR920000751A (ko) 1992-01-29
FI97055B (fi) 1996-06-28
AU634391B2 (en) 1993-02-18
DE69101740T2 (de) 1994-10-20

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