DE69915204D1 - Stabilisierte Proteinzusammensetzung - Google Patents

Stabilisierte Proteinzusammensetzung

Info

Publication number
DE69915204D1
DE69915204D1 DE69915204T DE69915204T DE69915204D1 DE 69915204 D1 DE69915204 D1 DE 69915204D1 DE 69915204 T DE69915204 T DE 69915204T DE 69915204 T DE69915204 T DE 69915204T DE 69915204 D1 DE69915204 D1 DE 69915204D1
Authority
DE
Germany
Prior art keywords
protein composition
stabilized protein
stabilized
composition
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69915204T
Other languages
English (en)
Other versions
DE69915204T2 (de
Inventor
Peter Connor Canning
Barbara Jean Kamicker
Kasra Kasraian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of DE69915204D1 publication Critical patent/DE69915204D1/de
Application granted granted Critical
Publication of DE69915204T2 publication Critical patent/DE69915204T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69915204T 1998-08-17 1999-08-06 Stabilisierte Proteinzusammensetzung Expired - Fee Related DE69915204T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9687698P 1998-08-17 1998-08-17
US96876P 1998-08-17

Publications (2)

Publication Number Publication Date
DE69915204D1 true DE69915204D1 (de) 2004-04-08
DE69915204T2 DE69915204T2 (de) 2004-07-29

Family

ID=22259521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69915204T Expired - Fee Related DE69915204T2 (de) 1998-08-17 1999-08-06 Stabilisierte Proteinzusammensetzung

Country Status (17)

Country Link
US (1) US20050232898A1 (de)
EP (1) EP0988861B1 (de)
JP (1) JP3641170B2 (de)
CN (1) CN1250282C (de)
AR (1) AR016504A1 (de)
AT (1) ATE260674T1 (de)
AU (2) AU767431B2 (de)
BR (1) BR9904150A (de)
CA (1) CA2280449A1 (de)
DE (1) DE69915204T2 (de)
DK (1) DK0988861T3 (de)
ES (1) ES2216447T3 (de)
HK (1) HK1026151A1 (de)
NZ (2) NZ337258A (de)
PT (1) PT988861E (de)
TW (1) TWI221773B (de)
ZA (1) ZA995201B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2337661A1 (en) 2000-02-29 2001-08-29 Pfizer Products Inc. Stabilized granulocyte colony stimulating factor
JP5052736B2 (ja) * 2001-05-30 2012-10-17 中外製薬株式会社 タンパク質製剤
ITMI20021684A1 (it) * 2002-07-29 2004-01-29 Therapicon Srl Composizione farmaceutica di peptide nasale
ITBA20020032A1 (it) * 2002-09-24 2004-03-25 Bio D Soc Metodo per stabilizzare le proteine per la conservazione ad alte temperature.
MXPA05012099A (es) * 2003-05-09 2006-02-08 Schering Ag Tratamiento de enfermedades respiratorias inflamatorias.
EP1682184B1 (de) 2003-11-04 2013-10-16 LEK Pharmaceuticals d.d. Stabile pharmazeutische zubereitungen enthaltend granulozyten-kolonie stimulierungsfaktor
EP1537876A1 (de) * 2003-12-01 2005-06-08 BioGeneriX AG Formulierung einer Erythropoietin Lösung
CA2545962A1 (en) * 2003-12-09 2005-07-07 Alcon, Inc. Use of organic buffering agents to enhance the antimicrobial activity of pharmaceutical compositions
PL1817048T3 (pl) * 2004-11-12 2014-07-31 Novo Nordisk As Stabilne preparaty peptydów insulinotropowych
SI1787658T1 (sl) * 2005-11-10 2012-07-31 Chemi Spa Formulacije z trajnim sproščanjem somatostatin analognih inhibitorjev rastnega hormona
DE102006009437A1 (de) 2006-03-01 2007-09-13 Bioceuticals Arzneimittel Ag G-CSF-Flüssigformulierung
AU2007309616B2 (en) 2006-10-20 2011-10-06 Amgen Inc. Stable polypeptide formulations
US8562967B2 (en) 2007-08-27 2013-10-22 Biogenerix Ag Stable liquid formulations of G-CSF
KR101553085B1 (ko) * 2007-10-09 2015-09-14 솔레니스 테크놀러지스 케이맨, 엘.피. 가교제-함유 접착제 조성물
WO2010011735A2 (en) * 2008-07-23 2010-01-28 Ambrx, Inc. Modified bovine g-csf polypeptides and their uses
AR083006A1 (es) * 2010-09-23 2013-01-23 Lilly Co Eli Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
ITMI20120338A1 (it) * 2012-03-06 2013-09-07 Dr Andrea Bignotti Preparato terapeutico e procedimento di preparazione di detto preparato terapeutico
GB2516808A (en) * 2013-05-31 2015-02-11 Innova Biosciences Ltd Antibody composition and buffer system therefor
MX2017008881A (es) 2015-01-05 2017-11-13 Univ Cornell Composiciones y metodos que usan il-8 para mejorar produccion de leche y salud reproductiva en mamiferos.
US11464831B2 (en) 2015-01-05 2022-10-11 Cornell University Compositions and methods using IL-8 for improving health of mammals
EP3554257B1 (de) 2016-12-15 2023-07-12 Société des Produits Nestlé S.A. Zusammensetzungen und verfahren zur modulation von weissen blutkörperchen oder neutrophilen in einem haustier
EP3771463A1 (de) 2019-07-29 2021-02-03 Ludwig-Maximilians-Universität München Stabilisierung therapeutischer proteine mit piperazin- oder morpholinhaltigen zwitterionischen puffersubstanzen
CN116836920B (zh) * 2023-08-21 2024-05-24 广东横琴粤澳深度合作区齐美国际干细胞医院有限公司 一种无血清培养基及其制备间充质干细胞的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0080879B1 (de) * 1981-11-28 1986-10-01 Sunstar Kabushiki Kaisha Stabilisiertes Interferon enthaltende pharmazeutische Zusammensetzung
JPS6069037A (ja) * 1983-09-26 1985-04-19 Sunstar Inc エリテマト−デス治療用外用剤
US4605555A (en) * 1984-09-20 1986-08-12 Sun Star Kabushiki Kaisha Composition and method for treating keratosic disorder of skin and mucosa
JPH0618781B2 (ja) * 1986-10-18 1994-03-16 中外製薬株式会社 感染症治療剤
EP0719860B1 (de) * 1988-05-13 2009-12-16 Amgen Inc. Verfahren zur Isolierung und Reinigung von G-CSF
US5013714A (en) * 1988-12-15 1991-05-07 Lindstrom Richard L Viscoelastic solution
US6066469A (en) * 1990-03-08 2000-05-23 Ferro Dynamics, Inc. Cloning, expression, and uses of human lactoferrin
DE4242919A1 (de) * 1992-12-18 1994-06-23 Boehringer Mannheim Gmbh Verfahren zur Herstellung von lagerstabilen wässrigen pharmazeutischen Zubereitungen von G-CSF
US5580856A (en) * 1994-07-15 1996-12-03 Prestrelski; Steven J. Formulation of a reconstituted protein, and method and kit for the production thereof

Also Published As

Publication number Publication date
AU4450199A (en) 2000-03-09
ES2216447T3 (es) 2004-10-16
DK0988861T3 (da) 2004-04-19
TWI221773B (en) 2004-10-11
NZ510140A (en) 2005-01-28
JP2000063264A (ja) 2000-02-29
BR9904150A (pt) 2000-12-26
EP0988861B1 (de) 2004-03-03
AU767431B2 (en) 2003-11-13
ATE260674T1 (de) 2004-03-15
CN1250282C (zh) 2006-04-12
US20050232898A1 (en) 2005-10-20
JP3641170B2 (ja) 2005-04-20
AR016504A1 (es) 2001-07-04
ZA995201B (en) 2001-02-16
PT988861E (pt) 2004-06-30
AU2004200568A1 (en) 2004-03-11
EP0988861A1 (de) 2000-03-29
NZ337258A (en) 2001-04-27
CA2280449A1 (en) 2000-02-17
CN1250668A (zh) 2000-04-19
HK1026151A1 (en) 2000-12-08
DE69915204T2 (de) 2004-07-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee