DE69304883D1 - Xanthin Derivate - Google Patents

Xanthin Derivate

Info

Publication number
DE69304883D1
DE69304883D1 DE69304883T DE69304883T DE69304883D1 DE 69304883 D1 DE69304883 D1 DE 69304883D1 DE 69304883 T DE69304883 T DE 69304883T DE 69304883 T DE69304883 T DE 69304883T DE 69304883 D1 DE69304883 D1 DE 69304883D1
Authority
DE
Germany
Prior art keywords
lower alkyl
independently represent
chem
represent hydrogen
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69304883T
Other languages
English (en)
Other versions
DE69304883T2 (de
Inventor
Fumio Suzuki
Junichi Shimada
Nobuaki Koike
Hiroshi Kase
Joji Nakamura
Shizuo Shiozaki
Hiromi Nonaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of DE69304883D1 publication Critical patent/DE69304883D1/de
Application granted granted Critical
Publication of DE69304883T2 publication Critical patent/DE69304883T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69304883T 1992-12-24 1993-12-23 Xanthin Derivate Expired - Fee Related DE69304883T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34411692 1992-12-24

Publications (2)

Publication Number Publication Date
DE69304883D1 true DE69304883D1 (de) 1996-10-24
DE69304883T2 DE69304883T2 (de) 1997-05-15

Family

ID=18366763

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69304883T Expired - Fee Related DE69304883T2 (de) 1992-12-24 1993-12-23 Xanthin Derivate

Country Status (6)

Country Link
US (1) US5670498A (de)
EP (1) EP0607607B1 (de)
AT (1) ATE143019T1 (de)
CA (1) CA2112031A1 (de)
DE (1) DE69304883T2 (de)
NO (1) NO300925B1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69526822T2 (de) * 1994-02-23 2003-01-23 Kyowa Hakko Kogyo K.K., Tokio/Tokyo Xanthin-derivate
US6727259B2 (en) 1997-09-05 2004-04-27 Kyowa Hakko Kogyo Co., Ltd. Remedial agent for neural degeneration
US6403567B1 (en) * 1999-06-22 2002-06-11 Cv Therapeutics, Inc. N-pyrazole A2A adenosine receptor agonists
USRE47351E1 (en) 1999-06-22 2019-04-16 Gilead Sciences, Inc. 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists
US6815446B1 (en) 1999-08-31 2004-11-09 Vanderbilt University Selective antagonists of A2B adenosine receptors
CA2388176C (en) * 1999-10-29 2007-09-25 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for eating disorders
AU2001238665A1 (en) 2000-02-23 2001-09-03 Cv Therapeutics, Inc. Method of identifying partial agonists of the a2a receptor
AU2003259264A1 (en) * 2002-07-29 2004-02-16 Cv Therapeutics, Inc. Myocardial perfusion imaging using a2a receptor agonists
US8470801B2 (en) 2002-07-29 2013-06-25 Gilead Sciences, Inc. Myocardial perfusion imaging methods and compositions
US20050020915A1 (en) * 2002-07-29 2005-01-27 Cv Therapeutics, Inc. Myocardial perfusion imaging methods and compositions
US7148229B2 (en) * 2003-02-19 2006-12-12 Hoffman-La Roche Inc. Sulfonamide substituted xanthine derivatives
TWI346114B (en) 2003-09-29 2011-08-01 Method for stabilization of diarylvinylene compounds
EP1709967A4 (de) * 2004-01-28 2010-09-15 Kyowa Hakko Kirin Co Ltd Mittel zur behandlung von migräne
EP1802317A2 (de) 2004-10-20 2007-07-04 Cv Therapeutics, Inc. Verwendung von a2a-adenosin-rezeptoragonisten
ES2593028T3 (es) * 2006-02-03 2016-12-05 Gilead Sciences, Inc. Proceso para preparar un agonista de receptor de adenosina A2A y sus polimorfos
BRPI0716174A2 (pt) * 2006-09-01 2013-09-24 Cv Therapeutics Inc mÉtodos e composiÇÕes para aumentar a tolerabilidade de paciente durante mÉtodos de imagem do miocÁrdio.
US20090081120A1 (en) * 2006-09-01 2009-03-26 Cv Therapeutics, Inc. Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods
JP2011502101A (ja) * 2006-09-29 2011-01-20 ギリアード・パロ・アルト・インコーポレイテッド 肺疾患の病歴を有する患者における心筋画像化法
JP2010515081A (ja) * 2007-01-03 2010-05-06 ギリアード・パロ・アルト・インコーポレイテッド 心筋灌流画像化
US8871751B2 (en) * 2008-01-18 2014-10-28 The Board Of Trustees Of The University Of Illinois Compositions and methods relating to nuclear hormone and steroid hormone receptors including inhibitors of estrogen receptor alpha-mediated gene expression and inhibition of breast cancer
US20100086483A1 (en) * 2008-09-29 2010-04-08 Gilead Palo Alto, Inc. Method of multidetector computed tomagraphy
CN110981876B (zh) * 2018-12-21 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途
US20220202822A1 (en) * 2019-04-24 2022-06-30 Sunshine Lake Pharma Co., Ltd. 8-substituted aryl vinyl xanthine derivatives and uses thereof
CN111072663B (zh) * 2019-12-12 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途
CN111018856B (zh) * 2019-12-12 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途
CA3170917A1 (en) * 2020-03-10 2021-09-16 Mark Williams Purine compounds for treating disorders
CN113248505B (zh) * 2021-06-09 2021-09-21 南京安杰新生物医药有限公司 伊曲茶碱去甲基杂质的制备方法
WO2023097402A1 (en) * 2021-12-03 2023-06-08 Marvel Biotechnology Purine compounds for treating disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452788A (en) * 1982-04-21 1984-06-05 Warner-Lambert Company Substituted 8-phenylxanthines
GB8510758D0 (en) * 1985-04-27 1985-06-05 Wellcome Found Compounds
ES2152207T3 (es) * 1989-10-20 2001-02-01 Kyowa Hakko Kogyo Kk Derivados condensados de la purina.
EP0559893B1 (de) * 1990-10-18 1999-02-03 Kyowa Hakko Kogyo Co., Ltd. Xanthinderivate

Also Published As

Publication number Publication date
NO300925B1 (no) 1997-08-18
ATE143019T1 (de) 1996-10-15
NO934792L (no) 1994-06-27
EP0607607A1 (de) 1994-07-27
CA2112031A1 (en) 1994-06-25
NO934792D0 (no) 1993-12-23
EP0607607B1 (de) 1996-09-18
DE69304883T2 (de) 1997-05-15
US5670498A (en) 1997-09-23

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee