DE60335111D1 - Pegyliertes t20-polypeptid - Google Patents

Pegyliertes t20-polypeptid

Info

Publication number
DE60335111D1
DE60335111D1 DE60335111T DE60335111T DE60335111D1 DE 60335111 D1 DE60335111 D1 DE 60335111D1 DE 60335111 T DE60335111 T DE 60335111T DE 60335111 T DE60335111 T DE 60335111T DE 60335111 D1 DE60335111 D1 DE 60335111D1
Authority
DE
Germany
Prior art keywords
pegylated
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60335111T
Other languages
English (en)
Inventor
Pascal Sebastian Bailon
Chee-Youb Won
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE60335111D1 publication Critical patent/DE60335111D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • C07K14/16—HIV-1 ; HIV-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60335111T 2002-07-24 2003-07-16 Pegyliertes t20-polypeptid Expired - Lifetime DE60335111D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39819502P 2002-07-24 2002-07-24
PCT/EP2003/007710 WO2004013164A1 (en) 2002-07-24 2003-07-16 Pegylated t20 polypeptide

Publications (1)

Publication Number Publication Date
DE60335111D1 true DE60335111D1 (de) 2011-01-05

Family

ID=31495720

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60335111T Expired - Lifetime DE60335111D1 (de) 2002-07-24 2003-07-16 Pegyliertes t20-polypeptid

Country Status (24)

Country Link
US (1) US7049415B2 (de)
EP (1) EP1527088B1 (de)
JP (1) JP4381301B2 (de)
KR (1) KR100637981B1 (de)
CN (1) CN100357317C (de)
AR (1) AR040651A1 (de)
AT (1) ATE489401T1 (de)
AU (1) AU2003257467B2 (de)
BR (1) BR0312889A (de)
CA (1) CA2493534C (de)
DE (1) DE60335111D1 (de)
ES (1) ES2354609T3 (de)
GT (1) GT200300155A (de)
HR (1) HRP20050024A2 (de)
IL (2) IL166038A0 (de)
MX (1) MXPA05000797A (de)
NO (1) NO20050066L (de)
PA (1) PA8577701A1 (de)
PE (1) PE20040705A1 (de)
PL (1) PL375254A1 (de)
RU (1) RU2296769C2 (de)
TW (1) TW200416225A (de)
WO (1) WO2004013164A1 (de)
ZA (1) ZA200500258B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
PT1531791E (pt) 2002-06-07 2010-12-16 Dyax Corp Prevenção e redução da isquémia
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
EP1663281B1 (de) * 2003-08-29 2013-12-25 Dyax Corp. Poly-pegylierte proteasehemmer
CA2537113A1 (en) * 2003-08-29 2005-03-10 Dyax Corp. Modified protease inhibitors
MXPA06010505A (es) * 2004-03-15 2006-12-19 Nektar Therapeutics Al Corp Composiciones y conjugados, basados en polimeros, de inhibidores de ingreso de vih.
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
BRPI0609555A2 (pt) * 2005-04-08 2010-04-13 Lonza Ag sìntese de peptìdeo de alfa-espirais sobre resina peg
JP2010536870A (ja) * 2007-08-21 2010-12-02 ジェンザイム・コーポレーション カリクレイン阻害剤を用いた治療
EP2385843A4 (de) 2009-01-06 2013-02-27 Dyax Corp Behandlung von mukositis mit kallikrein-hemmern
EP2521568B1 (de) 2010-01-06 2018-07-25 Dyax Corp. Plasmakallikreinbindende proteine
US8816055B2 (en) 2011-01-06 2014-08-26 Dyax Corp. Plasma kallikrein binding proteins
JP6719384B2 (ja) 2014-03-27 2020-07-15 ダイアックス コーポレーション 糖尿病黄斑浮腫の治療のための組成物および方法
US20160151511A1 (en) 2014-12-02 2016-06-02 Antriabio, Inc. Proteins and protein conjugates with increased hydrophobicity
KR20180094028A (ko) 2015-12-11 2018-08-22 다이액스 코포레이션 혈장 칼리크레인 저해제 및 유전성 혈관부종 발작을 치료하기 위한 이의 용도

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US153694A (en) * 1874-08-04 Improvement in clothes-pounders
KR850004274A (ko) * 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
US5252714A (en) * 1990-11-28 1993-10-12 The University Of Alabama In Huntsville Preparation and use of polyethylene glycol propionaldehyde
US5464933A (en) * 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
CH690143A5 (de) * 1995-01-27 2000-05-15 Rieter Automotive Int Ag Lambda/4-Schallabsorber.
US5672662A (en) * 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US5990237A (en) * 1997-05-21 1999-11-23 Shearwater Polymers, Inc. Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
NZ507083A (en) * 1998-03-23 2003-10-31 Trimeris Inc Methods and compositions for peptide synthesis, in particular T-20 (DP-178) and T-20-like peptides
US6281331B1 (en) * 1998-03-23 2001-08-28 Trimeris, Inc. Methods and compositions for peptide synthesis
WO2000032772A2 (en) * 1998-11-30 2000-06-08 Eli Lilly And Company Erythropoietic compounds
JO2291B1 (en) * 1999-07-02 2005-09-12 اف . هوفمان لاروش ايه جي Erythropoietin derivatives
KR100488351B1 (ko) * 2001-12-11 2005-05-11 선바이오(주) 신규한 폴리에틸렌글리콜-프로피온알데히드 유도체

Also Published As

Publication number Publication date
AU2003257467A1 (en) 2004-02-23
EP1527088B1 (de) 2010-11-24
PA8577701A1 (es) 2004-02-07
GT200300155A (es) 2004-03-15
PL375254A1 (en) 2005-11-28
BR0312889A (pt) 2005-06-14
CN1671736A (zh) 2005-09-21
JP2006511455A (ja) 2006-04-06
US20040049018A1 (en) 2004-03-11
RU2296769C2 (ru) 2007-04-10
JP4381301B2 (ja) 2009-12-09
ZA200500258B (en) 2006-01-25
HRP20050024A2 (en) 2006-02-28
IL166038A (en) 2010-11-30
RU2005105577A (ru) 2005-10-27
US7049415B2 (en) 2006-05-23
IL166038A0 (en) 2006-01-15
KR20050027257A (ko) 2005-03-18
CN100357317C (zh) 2007-12-26
PE20040705A1 (es) 2004-10-14
WO2004013164A1 (en) 2004-02-12
CA2493534A1 (en) 2004-02-12
TW200416225A (en) 2004-09-01
ATE489401T1 (de) 2010-12-15
AR040651A1 (es) 2005-04-13
ES2354609T3 (es) 2011-03-16
AU2003257467B2 (en) 2008-02-28
MXPA05000797A (es) 2005-04-19
KR100637981B1 (ko) 2006-10-23
CA2493534C (en) 2010-01-26
NO20050066L (no) 2005-04-22
EP1527088A1 (de) 2005-05-04

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