DD141616A5 - Verfahren zur herstellung neuer antigenderivate - Google Patents

Verfahren zur herstellung neuer antigenderivate Download PDF

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Publication number
DD141616A5
DD141616A5 DD79211204A DD21120479A DD141616A5 DD 141616 A5 DD141616 A5 DD 141616A5 DD 79211204 A DD79211204 A DD 79211204A DD 21120479 A DD21120479 A DD 21120479A DD 141616 A5 DD141616 A5 DD 141616A5
Authority
DD
German Democratic Republic
Prior art keywords
carbamoyl
propyl
glucose
ethyl
carboxy
Prior art date
Application number
DD79211204A
Other languages
German (de)
English (en)
Inventor
Gerhard Baschang
Felix M Dietrich
Roland Gisler
Albert Hartmann
Jaroslav Stanek
Lajos Tarcsay
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27173419&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DD141616(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DD141616A5 publication Critical patent/DD141616A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6062—Muramyl peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DD79211204A 1978-02-24 1979-02-23 Verfahren zur herstellung neuer antigenderivate DD141616A5 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH203578 1978-02-24
CH377778 1978-04-07
CH539478 1978-05-18

Publications (1)

Publication Number Publication Date
DD141616A5 true DD141616A5 (de) 1980-05-14

Family

ID=27173419

Family Applications (1)

Application Number Title Priority Date Filing Date
DD79211204A DD141616A5 (de) 1978-02-24 1979-02-23 Verfahren zur herstellung neuer antigenderivate

Country Status (20)

Country Link
EP (1) EP0003833B2 (no)
JP (1) JPS54141718A (no)
AR (1) AR223833A1 (no)
AT (1) AT364718B (no)
AU (1) AU527549B2 (no)
CA (1) CA1138436A (no)
DD (1) DD141616A5 (no)
DK (1) DK161026C (no)
ES (2) ES477977A1 (no)
FI (1) FI66878C (no)
GB (1) GB2015534A (no)
GR (1) GR77615B (no)
HU (1) HU182011B (no)
IL (1) IL56724A (no)
NO (2) NO151201C (no)
NZ (1) NZ189756A (no)
PL (1) PL123315B1 (no)
PT (1) PT69281A (no)
SU (1) SU1055312A3 (no)
ZA (1) ZA79893B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54130516A (en) * 1978-03-31 1979-10-09 Yuuichi Yamamura Acyllnnacetylmuramylpeptide derivativeeantigen combination
FR2428050A1 (fr) * 1978-06-05 1980-01-04 Anvar Oligomeres de composes du type muramyl-peptide et medicaments les contenant
FR2428051A1 (fr) * 1978-06-05 1980-01-04 Anvar Nouveaux composes du type muramyl-peptide et medicaments les contenant
EP0013856B1 (en) 1978-12-22 1983-03-09 ANVAR Agence Nationale de Valorisation de la Recherche New compounds associating peptidyl or aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds
FR2446292A1 (fr) * 1979-01-12 1980-08-08 Anvar Muramyl-peptides fixes sur polymeres peptidiques et medicaments les contenant
FR2449697A1 (fr) 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
JPS5618996A (en) * 1979-06-21 1981-02-23 Dai Ichi Seiyaku Co Ltd Muramyldipeptide derivative
DK156252C (da) * 1979-07-31 1989-12-18 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af di-, tri- eller tetrapeptidderivater eller salte deraf
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
EP0038153A3 (en) * 1980-04-15 1982-12-22 Beecham Group Plc Modified allergens
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4497729A (en) * 1980-12-01 1985-02-05 Fujisawa Pharmaceutical Co., Ltd. Peptide, process for preparation thereof and use thereof
FR2522967B1 (fr) * 1982-03-15 1986-03-07 Anvar Conjugues d'haptenes et de muramyl-peptides, doues d'activite immunogene et compositions les contenant
US4587046A (en) * 1982-05-18 1986-05-06 The Regents Of The University Of California Drug-carrier conjugates
FR2558165B1 (fr) * 1984-01-17 1986-07-04 Anvar Nouveaux conjugues d'oligo-muramylpeptides et compositions biologiques les contenant pour l'activation des macrophages
FR2569984B1 (fr) * 1984-09-12 1987-08-14 Anvar Molecule synthetique contenant une pluralite d'epitopes distincts, procede pour son obtention et application a la production de polyvaccins
KR20210098476A (ko) * 2018-11-30 2021-08-10 추가이 세이야쿠 가부시키가이샤 펩티드 화합물 또는 아마이드 화합물의 탈보호법 및 고상 반응에 있어서의 탈수지 방법, 및 펩티드 화합물의 제조 방법
IL306006A (en) 2021-03-19 2023-11-01 Trained Therapeutix Discovery Inc Compounds for controlling trained immunity, and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH453269A4 (no) * 1968-03-29 1973-01-31
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
CH613709A5 (en) * 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives
FR2343482A1 (fr) * 1976-03-10 1977-10-07 Anvar La 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-seryl-d-isoglutamine et medicaments la contenant
JPS52139018A (en) * 1976-03-10 1977-11-19 Anvar Immuno adjuvant and antiinfection adjuvant composed of mainly nnacetyll muramiccllalanyllddglutamic ester or nnacetyllmuramiccllalanylldd isoglutamic ester

Also Published As

Publication number Publication date
CA1138436A (en) 1982-12-28
PT69281A (de) 1979-03-01
JPS54141718A (en) 1979-11-05
GB2015534A (en) 1979-09-12
NO151088C (no) 1985-02-06
ES483558A1 (es) 1980-04-16
SU1055312A3 (ru) 1983-11-15
NO151201C (no) 1985-02-27
DK79779A (da) 1979-08-25
PL213696A1 (no) 1980-07-14
HU182011B (en) 1983-12-28
NZ189756A (en) 1982-05-31
IL56724A0 (en) 1979-05-31
AU527549B2 (en) 1983-03-10
ES477977A1 (es) 1980-01-16
NO793993L (no) 1979-08-27
JPH0130809B2 (no) 1989-06-22
EP0003833A2 (de) 1979-09-05
DK161026B (da) 1991-05-21
EP0003833A3 (en) 1980-02-06
EP0003833B2 (de) 1990-12-19
FI66878C (fi) 1984-12-10
AT364718B (de) 1981-11-10
FI790584A (fi) 1979-08-25
ZA79893B (en) 1980-03-26
NO151088B (no) 1984-10-29
DK161026C (da) 1991-10-28
EP0003833B1 (de) 1983-07-20
AR223833A1 (es) 1981-09-30
NO790626L (no) 1979-08-27
PL123315B1 (en) 1982-10-30
ATA142079A (de) 1981-04-15
AU4454679A (en) 1979-08-30
IL56724A (en) 1982-12-31
NO151201B (no) 1984-11-19
GR77615B (no) 1984-09-25
FI66878B (fi) 1984-08-31

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