CZ307180B6 - Konjugát obsahující superantigen a protilátkovou skupinu, a farmaceutický prostředek s obsahem konjugátu - Google Patents

Konjugát obsahující superantigen a protilátkovou skupinu, a farmaceutický prostředek s obsahem konjugátu Download PDF

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Publication number
CZ307180B6
CZ307180B6 CZ2003-3559A CZ20033559A CZ307180B6 CZ 307180 B6 CZ307180 B6 CZ 307180B6 CZ 20033559 A CZ20033559 A CZ 20033559A CZ 307180 B6 CZ307180 B6 CZ 307180B6
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CZ
Czechia
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ser
leu
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CZ2003-3559A
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Czech (cs)
English (en)
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CZ20033559A3 (en
Inventor
Göran Forsberg
Eva Erlandsson
Per Antonsson
Björn Walse
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Active Biotech Ab
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Publication of CZ20033559A3 publication Critical patent/CZ20033559A3/cs
Publication of CZ307180B6 publication Critical patent/CZ307180B6/cs

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L51/00User-to-user messaging in packet-switching networks, transmitted according to store-and-forward or real-time protocols, e.g. e-mail
    • H04L51/06Message adaptation to terminal or network requirements
    • H04L51/063Content adaptation, e.g. replacement of unsuitable content
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L51/00User-to-user messaging in packet-switching networks, transmitted according to store-and-forward or real-time protocols, e.g. e-mail
    • H04L51/58Message adaptation for wireless communication

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Signal Processing (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CZ2003-3559A 2001-06-28 2002-06-19 Konjugát obsahující superantigen a protilátkovou skupinu, a farmaceutický prostředek s obsahem konjugátu CZ307180B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0102327A SE0102327D0 (sv) 2001-06-28 2001-06-28 A novel engineered superantigen for human therapy

Publications (2)

Publication Number Publication Date
CZ20033559A3 CZ20033559A3 (en) 2004-06-16
CZ307180B6 true CZ307180B6 (cs) 2018-02-28

Family

ID=20284677

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ2003-3559A CZ307180B6 (cs) 2001-06-28 2002-06-19 Konjugát obsahující superantigen a protilátkovou skupinu, a farmaceutický prostředek s obsahem konjugátu

Country Status (28)

Country Link
US (3) US7125554B2 (ru)
EP (1) EP1406657B1 (ru)
JP (1) JP4523773B2 (ru)
KR (1) KR100961054B1 (ru)
CN (1) CN1522156B (ru)
BG (1) BG66321B1 (ru)
BR (1) BRPI0210568B8 (ru)
CA (1) CA2451847C (ru)
CZ (1) CZ307180B6 (ru)
DK (1) DK1406657T3 (ru)
EE (1) EE05475B1 (ru)
ES (1) ES2564041T3 (ru)
HK (1) HK1067980A1 (ru)
HR (1) HRP20031054B1 (ru)
HU (1) HUP0400313A3 (ru)
IL (2) IL159562A0 (ru)
IS (1) IS2986B (ru)
MX (1) MXPA03011761A (ru)
NO (1) NO333676B1 (ru)
NZ (1) NZ529827A (ru)
PL (1) PL216516B1 (ru)
RS (1) RS52581B (ru)
RU (1) RU2307837C2 (ru)
SE (1) SE0102327D0 (ru)
SK (1) SK16112003A3 (ru)
UA (1) UA85993C2 (ru)
WO (1) WO2003002143A1 (ru)
ZA (1) ZA200309150B (ru)

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SE0102327D0 (sv) 2001-06-28 2001-06-28 Active Biotech Ab A novel engineered superantigen for human therapy
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US8710200B2 (en) 2011-03-31 2014-04-29 Moderna Therapeutics, Inc. Engineered nucleic acids encoding a modified erythropoietin and their expression
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
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US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
CA2868996A1 (en) 2012-04-02 2013-10-10 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
HRP20220607T1 (hr) 2012-11-26 2022-06-24 Modernatx, Inc. Terminalno modificirana rna
CN103965302B (zh) * 2013-01-29 2019-05-28 军事科学院军事医学研究院微生物流行病研究所 一种重组超抗原seb突变体,其制备方法及应用
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
WO2015048744A2 (en) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucleotides encoding immune modulating polypeptides
WO2015051214A1 (en) 2013-10-03 2015-04-09 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor
JP7161938B2 (ja) 2016-01-10 2022-10-27 ネオティーエックス セラピューティクス リミテッド スーパー抗原媒介性癌免疫療法の能力を増強するための方法および組成物
WO2019023341A1 (en) * 2017-07-27 2019-01-31 Integrated Biotherapeutics, Inc. IMMUNOGENIC COMPOSITION COMPRISING A MELTING PEPTIDE DERIVED FROM TOXOIDS OF SUPERANTIGENES
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Also Published As

Publication number Publication date
CN1522156B (zh) 2012-10-10
IS7083A (is) 2003-12-18
KR20040015264A (ko) 2004-02-18
JP2005503362A (ja) 2005-02-03
ZA200309150B (en) 2005-01-26
CN1522156A (zh) 2004-08-18
BG108499A (en) 2005-03-31
EP1406657A1 (en) 2004-04-14
SK16112003A3 (en) 2004-11-03
RU2307837C2 (ru) 2007-10-10
RS52581B (en) 2013-04-30
US20070082001A1 (en) 2007-04-12
US20100111978A1 (en) 2010-05-06
EE05475B1 (et) 2011-10-17
CA2451847C (en) 2012-10-16
HRP20031054B1 (hr) 2016-12-30
UA85993C2 (ru) 2009-03-25
ES2564041T3 (es) 2016-03-17
IS2986B (is) 2017-09-15
DK1406657T3 (en) 2016-03-07
IL159562A (en) 2010-12-30
KR100961054B1 (ko) 2010-06-01
US20030039655A1 (en) 2003-02-27
US7125554B2 (en) 2006-10-24
WO2003002143A1 (en) 2003-01-09
IL159562A0 (en) 2004-06-01
NZ529827A (en) 2005-06-24
YU101503A (en) 2006-05-25
HUP0400313A3 (en) 2006-02-28
BG66321B1 (bg) 2013-05-31
BRPI0210568B8 (pt) 2021-05-25
BR0210568A (pt) 2004-08-03
PL368048A1 (en) 2005-03-21
MXPA03011761A (es) 2004-04-02
EP1406657B1 (en) 2015-12-30
CA2451847A1 (en) 2003-01-09
RU2004102199A (ru) 2005-05-20
HK1067980A1 (en) 2005-04-22
EE200400037A (et) 2004-04-15
BRPI0210568B1 (pt) 2020-10-13
NO20035773L (no) 2004-02-27
HUP0400313A2 (hu) 2004-09-28
US7615225B2 (en) 2009-11-10
HRP20031054A2 (en) 2004-04-30
JP4523773B2 (ja) 2010-08-11
SE0102327D0 (sv) 2001-06-28
CZ20033559A3 (en) 2004-06-16
NO333676B1 (no) 2013-08-05
PL216516B1 (pl) 2014-04-30

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