CY1118807T1 - Πρωτεϊνες προσδεσης παρομοιες με αντισωμα διπλα μεταβλητης περιοχης που διαθετουν εναν διασταυρουμενο προσανατολισμο περιοχης προσδεσης - Google Patents

Πρωτεϊνες προσδεσης παρομοιες με αντισωμα διπλα μεταβλητης περιοχης που διαθετουν εναν διασταυρουμενο προσανατολισμο περιοχης προσδεσης

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Publication number
CY1118807T1
CY1118807T1 CY20161100806T CY161100806T CY1118807T1 CY 1118807 T1 CY1118807 T1 CY 1118807T1 CY 20161100806 T CY20161100806 T CY 20161100806T CY 161100806 T CY161100806 T CY 161100806T CY 1118807 T1 CY1118807 T1 CY 1118807T1
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Cyprus
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area
double
crossroading
experience
protection accessories
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CY20161100806T
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English (en)
Inventor
Nicolas Baurin
Christian Beil
Carsten Corvey
Christian Lange
Danxi Li
Vincent Mikol
Anke Steinmetz
Ercole Rao
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Sanofi
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46927552&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1118807(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi filed Critical Sanofi
Publication of CY1118807T1 publication Critical patent/CY1118807T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02—Immunomodulators
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract

Η εφεύρεση παρέχει παρόμοιες με αντίσωμα πρωτεΐνες πρόσδεσης που περιλαμβάνουν τέσσερις πολυπεπτιδικές αλυσίδες οι οποίες σχηματίζουν τέσσερις θέσεις πρόσδεσης αντιγόνου, όπου κάθε ζεύγος των πολυπεπτιδίων που σχηματίζουν μια παρόμοια με αντίσωμα πρωτεΐνη πρόσδεσης διαθέτει διπλά μεταβλητές επικράτειες που έχουν διασταυρούμενο προσανατολισμό. Η εφεύρεση παρέχει επίσης μεθόδους για την κατασκευή τέτοιων παρόμοιων με αντιγόνο πρωτεϊνών πρόσδεσης.
CY20161100806T 2011-03-28 2016-08-17 Πρωτεϊνες προσδεσης παρομοιες με αντισωμα διπλα μεταβλητης περιοχης που διαθετουν εναν διασταυρουμενο προσανατολισμο περιοχης προσδεσης CY1118807T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161468276P 2011-03-28 2011-03-28
FR1160311 2011-11-14
PCT/US2012/030948 WO2012135345A1 (en) 2011-03-28 2012-03-28 Dual variable region antibody-like binding proteins having cross-over binding region orientation

Publications (1)

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CY1118807T1 true CY1118807T1 (el) 2018-01-10

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US (7) US20120251541A1 (el)
EP (4) EP3112380A1 (el)
JP (6) JP6023172B2 (el)
KR (3) KR102607708B1 (el)
CN (3) CN110256568A (el)
AR (4) AR085726A1 (el)
AU (1) AU2012236603B2 (el)
BR (3) BR112013024758B1 (el)
CA (1) CA2831603C (el)
CL (1) CL2018001827A1 (el)
CO (1) CO6781527A2 (el)
CY (1) CY1118807T1 (el)
DK (2) DK3199547T3 (el)
ES (1) ES2588306T3 (el)
HR (1) HRP20161030T1 (el)
HU (1) HUE028230T2 (el)
IL (4) IL299392A (el)
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MA (1) MA35051B1 (el)
MX (1) MX338907B (el)
MY (1) MY164906A (el)
PL (2) PL2691416T3 (el)
PT (1) PT2691416T (el)
RS (2) RS55014B1 (el)
RU (1) RU2695880C2 (el)
SG (1) SG193916A1 (el)
SI (2) SI2691416T1 (el)
TW (6) TWI671315B (el)
UY (1) UY33983A (el)
WO (1) WO2012135345A1 (el)
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