CY1109366T1 - Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης - Google Patents

Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης

Info

Publication number
CY1109366T1
CY1109366T1 CY20091100935T CY091100935T CY1109366T1 CY 1109366 T1 CY1109366 T1 CY 1109366T1 CY 20091100935 T CY20091100935 T CY 20091100935T CY 091100935 T CY091100935 T CY 091100935T CY 1109366 T1 CY1109366 T1 CY 1109366T1
Authority
CY
Cyprus
Prior art keywords
decan
triazazepiro
substituted compounds
compounds
triazaspiro
Prior art date
Application number
CY20091100935T
Other languages
English (en)
Inventor
Corinna Sundermann
Bernd Sundermann
Stefan Oberbörsch
Werner Englberger
Hagen-Heinrich Hennies
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of CY1109366T1 publication Critical patent/CY1109366T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)

Abstract

Η παρούσα εφεύρεση αφορά υποκατεστημένες ενώσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης, μεθόδους για την παρασκευή τους, φάρμακα που περιέχουν την ένωση αυτή, καθώς και τη χρησιμοποίηση των ενώσεων αυτών για την παρασκευή φαρμάκων.
CY20091100935T 2004-03-22 2009-09-08 Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης CY1109366T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004014304A DE102004014304A1 (de) 2004-03-22 2004-03-22 Substituierte 1,4,8- Triazaspiro[4,5]decan-2-on-Verbindungen
EP05716300A EP1730144B1 (de) 2004-03-22 2005-03-22 Substituierte 1,4,8-triazaspiro¬4.5 decan-2-on-verbindungen

Publications (1)

Publication Number Publication Date
CY1109366T1 true CY1109366T1 (el) 2014-07-02

Family

ID=34961965

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100935T CY1109366T1 (el) 2004-03-22 2009-09-08 Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης

Country Status (13)

Country Link
US (1) US7560468B2 (el)
EP (1) EP1730144B1 (el)
JP (1) JP5148997B2 (el)
AT (1) ATE433450T1 (el)
CA (1) CA2560684A1 (el)
CY (1) CY1109366T1 (el)
DE (2) DE102004014304A1 (el)
DK (1) DK1730144T3 (el)
ES (1) ES2328496T3 (el)
PL (1) PL1730144T3 (el)
PT (1) PT1730144E (el)
SI (1) SI1730144T1 (el)
WO (1) WO2005095398A1 (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2655203A1 (en) * 2006-06-14 2007-12-21 Virochem Pharma Inc. Spirotropane compounds
US8653068B2 (en) 2009-10-30 2014-02-18 Pain Therapeutics, Inc. Filamin A binding anti-inflammatory and analgesic
US9340558B2 (en) 2007-11-02 2016-05-17 Pain Therapeutics Inc. Filamin a binding anti-inflammatory and analgesic
US8614324B2 (en) * 2008-10-31 2013-12-24 Pain Therapeutics, Inc. Filamin A binding anti-inflammatory and analgesic
EP2498600B1 (en) * 2008-10-31 2016-03-02 Pain Therapeutics, Inc. Filamin a-binding anti-inflammatory analgesic
EP2488177B1 (en) * 2008-10-31 2016-10-12 Pain Therapeutics, Inc. Filamin a binding anti-inflammatory and analgesic
US8580808B2 (en) * 2009-10-30 2013-11-12 Pain Therapeutic, Inc. Filamin A-binding anti-inflammatory analgesic
US8580809B2 (en) * 2009-10-30 2013-11-12 Pain Therapeutics, Inc. Filamin A-binding anti-inflammatory analgesic
EP2872899B1 (en) 2012-07-13 2018-07-11 Pain Therapeutics, Inc. Alzheimer's disease assay in a living patient
WO2014011917A2 (en) 2012-07-13 2014-01-16 Pain Therapeutics, Inc. A method of inhibiting tau phosphorylation
US9433604B2 (en) 2013-10-08 2016-09-06 Pain Therapeutics Inc. Method for inhibiting growth of cancer cells
WO2020172584A1 (en) * 2019-02-21 2020-08-27 Pain Therapeutics, Inc. Solid polymorphs of a flna-binding compound and its hydrochloride salts

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725389A (en) * 1971-07-02 1973-04-03 American Home Prod Adducts of delta-aminobenzylpenicillin and n-substituted-4-piperidones
JP2575446B2 (ja) * 1988-02-12 1997-01-22 武田薬品工業株式会社 トリアザスピロ化合物
TW251284B (el) * 1992-11-02 1995-07-11 Pfizer
ES2157256T3 (es) * 1993-03-16 2001-08-16 Pfizer Derivados de naftaleno.
AU1682400A (en) * 1998-12-09 2000-06-26 Banyu Pharmaceutical Co., Ltd. 4-oxoimidazolidine-2-spiro-nitrogenous heterocycle compounds
WO2001096337A1 (fr) * 2000-06-14 2001-12-20 Banyu Pharmaceutical Co.,Ltd Composes heterocycliques 4-oxoimidazolidine-2-spiro-azotes
ATE396995T1 (de) * 2001-07-23 2008-06-15 Banyu Pharma Co Ltd 4-oxoimidazolidin-2-spiro piperidin derivat

Also Published As

Publication number Publication date
DE502005007459D1 (de) 2009-07-23
DE102004014304A1 (de) 2005-10-06
JP5148997B2 (ja) 2013-02-20
CA2560684A1 (en) 2005-10-13
US7560468B2 (en) 2009-07-14
EP1730144A1 (de) 2006-12-13
PT1730144E (pt) 2009-09-14
ATE433450T1 (de) 2009-06-15
JP2007529568A (ja) 2007-10-25
PL1730144T3 (pl) 2009-11-30
SI1730144T1 (sl) 2009-12-31
DK1730144T3 (da) 2009-10-12
WO2005095398A1 (de) 2005-10-13
EP1730144B1 (de) 2009-06-10
US20070015783A1 (en) 2007-01-18
ES2328496T3 (es) 2009-11-13

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