CN210408354U - X-ray capsule 3D endoscope system - Google Patents
X-ray capsule 3D endoscope system Download PDFInfo
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- CN210408354U CN210408354U CN201920452395.7U CN201920452395U CN210408354U CN 210408354 U CN210408354 U CN 210408354U CN 201920452395 U CN201920452395 U CN 201920452395U CN 210408354 U CN210408354 U CN 210408354U
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Abstract
The utility model provides an X-ray capsule 3D endoscope system, which comprises an in-vivo imaging capsule, an in-vitro signal transceiver and an in-vitro image processing system, wherein the in-vitro signal transceiver is communicated with the in-vivo imaging capsule in a wireless mode; the in-vitro image processing system is connected with the in-vitro signal receiving and sending device in a wired or wireless mode and sends a control command to the capsule electronic system through the in-vitro signal receiving and sending device; the in-vivo imaging capsule is used for emitting radiation beams, detecting attenuation signals generated by reflection of intestinal walls and intestinal contents and transmitting the attenuation signals to the in-vitro signal transceiver; the in-vitro signal transceiver is used for transmitting the received attenuation signal to the in-vitro image processing system; the in-vitro image processing system is used for carrying out post-processing on the image signals collected by the in-vivo imaging capsule. The system has the characteristics of safety, reliability, high detection precision, small influence on normal life of patients and the like.
Description
Technical Field
The utility model relates to the technical field of medical equipment, especially, relate to an X ray capsule 3D endoscope system.
Background
Colorectal cancer is a common lethal disease and is highly malignant. According to statistics, 33.1 million new cases of colorectal cancer occur every year in China, 15.9 million patients die of the colorectal cancer every year, and the incidence rate is the third of all malignant tumors. Intestinal polyps are a common abnormal tissue growth, formed in the intima of the colon or rectum, and are one of the major risk factors for colorectal cancer. Traditional colorectal endoscopy is the most common colorectal cancer detection method, early cancer tissues or precancerous polyps are discovered and eradicated through an endoscope, and the survival rate and the cure rate of patients can be greatly improved. The discovery of early diseased tissue and surgical removal is therefore critical to the treatment of colorectal cancer.
Traditional colorectal endoscopy requires that the surface of colorectal mucosa is clearly visible, and the cleanliness of intestinal tracts determines the quality, difficulty, speed and completeness of examination. Before examination, a patient needs to fast solid food for 2 to 3 days in advance, and drink a large amount of special dilute solution, take special laxatives orally or wash intestinal tracts, so that the colorectal is kept clean, and the normal life of the patient is greatly influenced. During the examination, the patient can feel pressure, abdominal distension or colic, and the enteroscopy needs to last for 1 to 2 hours, which causes a large physical and psychological burden to the patient. Meanwhile, the traditional colorectal endoscope has a limited detection range and a small visual angle, and can not effectively and comprehensively detect the colorectal cancer. Moreover, the observation of the traditional colorectal endoscope is a two-dimensional image, the three-dimensional structure information of pathological tissues such as polyps and the like cannot be acquired, and intestinal hemorrhage and even intestinal perforation are easily caused in the resection operation. Post-surgery symptoms of colic, abdominal distension, bleeding or fever may develop. Therefore, the traditional colorectal endoscopy preparation period and the examination duration are long, the influence of the cleaning condition in the intestinal tract on the detection accuracy is large, and the whole examination period easily causes large burden on the body and mind of a patient. In addition, repeated use of the enteroscope increases the difficulty and cost of sterilization and increases the probability of cross-infection and complications. Consequently design a section high efficiency, convenient, safe, disposable, can reflect the X line capsule 3D endoscope system of intestinal three-dimensional structure information comprehensively simultaneously, can not only facilitate for clinician, greatly reduce enteroscopy work load, can also save the disinfection cost, greatly reduced is because of the risk of operation or the improper production of disinfection. Meanwhile, the painless detection process can reduce the psychological and physiological burden of the patient to the greatest extent and improve the clinical popularity and acceptance of the colorectal endoscopy.
SUMMERY OF THE UTILITY MODEL
The utility model discloses the technical problem that will solve is: in order to overcome the deficiencies in the prior art, the utility model provides an X-ray capsule 3D endoscope system for solve traditional colorectal endoscopy duration cycle long, preparation work is numerous and diverse, disappearance three-dimensional structure information, patient's physical and mental burden is big, the operational difficulties and the disinfection process is loaded down with trivial details scheduling problem.
The utility model provides a technical scheme that its technical problem will adopt is: an X-ray capsule 3D endoscope system comprises an in-vivo imaging capsule, an in-vitro signal transceiver and an in-vitro image processing system, wherein the in-vitro signal transceiver is communicated with the in-vivo imaging capsule in a wireless mode; the in-vitro image processing system is connected with the in-vitro signal receiving and sending device in a wired or wireless mode and sends a control command to the capsule electronic system through the in-vitro signal receiving and sending device; the in-vivo imaging capsule is used for emitting radiation beams, detecting attenuation signals generated by reflection of intestinal walls and intestinal contents and transmitting the attenuation signals to the in-vitro signal transceiver; the in-vitro signal transceiver is used for transmitting the received attenuation signal to the in-vitro image processing system; the in-vitro image processing system is used for post-processing image signals collected by the in-vivo imaging capsule, and has the functions of image reconstruction, image three-dimensional display, image quantitative analysis and the like. Thereby completing the acquisition of images and realizing the three-dimensional reconstruction display of the intestinal canal inner wall images; and acquiring the space position and the path of the capsule imaging device to realize the path tracking of the in-vivo imaging capsule.
The X-ray capsule 3D endoscope system is characterized in that an in-vivo imaging capsule and an intestinal wall contrast agent are swallowed, an in-vitro signal transceiver is used for collecting fluorescence and Compton back scattering photon counting signals reflected by the intestinal wall after the contrast agent is enhanced, and three-dimensional structure drawing imaging is carried out.
Specifically, the in vivo imaging capsule comprises a radiation source group, a detector array, a capsule battery pack, a capsule central control system and a capsule electronic system which are sequentially arranged in a capsule shell from front to back, wherein the radiation source group is isolated from the detector array through a front end radioactive source shielding bottom plate; the capsule battery pack is positioned behind the capsule detector array, the capsule electronic system surrounds the periphery of the capsule battery pack, and the capsule electronic system is isolated from the detector array through a rear end bottom plate; the capsule central control system is positioned at the rear part of the capsule battery pack and is arranged in the rear half part of the capsule shell; the capsule battery pack provides power supply required by operation for the capsule detector array, the capsule electronic system and the capsule central control system through power lines.
Furthermore, the radioactive source group comprises a radioactive source container, at least three radioactive source collimators, radioactive substances, a radioactive source rotating shaft, a front end fixing device and a radioactive source shielding shell. The radioactive source collimator is arranged on the side face of the radioactive source container in a radial shape along the circumferential direction at equal intervals and at equal height, and the radioactive substance is arranged in the radioactive source container. The tail end of the radioactive source rotating shaft is fixed on the front end radioactive source shielding bottom plate and is connected with the rotary driving interface of the front end radioactive source shielding bottom plate, and the front end of the radioactive source rotating shaft is connected with the tail end of the radioactive source container to drive the radioactive source container to rotate. The capsule detector array is isolated from the radiation source group by the front end radiation source shielding bottom plate. The radioactive source group is isolated from the front half part of the capsule shell by the radioactive source shielding shell, the positions of the radioactive source shielding shell corresponding to the radioactive source collimators are provided with openings with the same number as the radioactive source collimators, and the tail ends of the radioactive source collimators are fixed at the openings of the radioactive source shielding shell so as to irradiate the intestinal wall by rays. Preferably, the number of the radioactive source collimators is three. The front end fixing device fixes the radiation source group in the capsule shell. Meanwhile, the radioactive substance in the in-vivo imaging capsule is made into a small spherical solid by radioactive powder or is made into a small spherical solid by infiltrating the radioactive substance into porous substances with adsorption capacity. Meanwhile, the half-life period of the radioactive pellets is at least 4-5 days, so that enough imaging radioactive sources are provided in the period of being discharged out of the body through the intestinal tract. Before the X-ray capsule 3D endoscope system is used, a patient needs to swallow a small amount of intestinal canal wall contrast agent and an in-vivo imaging capsule, an in-vitro signal device detects that the in-vivo imaging capsule reaches a designated position and then starts imaging, and finally the in-vivo imaging capsule is discharged out of the body along with excrement through an intestinal canal.
Further, the preparation process of the radioactive pellet used in the in vivo imaging capsule mainly comprises two steps of radioactive substance preparation and radioactive source solid forming. The preparation method of the radioactive substance mainly comprises the following steps: preparing concentrated radioactive substances, oxidizing and separating the radioactive substances, separating isotopes, capturing the radioactive substances and reducing the radioactive substances; the radioactive source solid forming step mainly comprises: and (4) carrying out spherical forming and forming reinforcement. Through the steps, the radioactive substance is prepared into the globular radioactive source with stable half-life period, moderate radiation intensity and stable forming, and is arranged in the radioactive source container of the in-vivo imaging capsule, so that a reliable radioactive source is provided for capsule imaging. Wherein, the radioactive substance hungry (Os) is mainly used for preparing the stable and reliable imaging radioactive source. In one embodiment, the radioactive source preparation material is Os. In the step of preparing the concentrated radioactive substance, Os190 is bombarded with a stream of hot neutrons to obtain a mixed powder of the concentrated Os190, Os191, and iridium 192(Ir 192). In the isotope separation step, Os190 and Os191 obtained from the preparation of the concentrated radioactive substance are separated by an electromagnetic method, a centrifugal method, a thermal diffusion-equivalent isotope separation method, Os191 is retained, and Os190 is removed. At the positionIn the radioactive substance reduction preparation step, the Os191 and Ir192 mixture obtained in the isotope separation step is subjected to oxidation treatment by heating, and the osmium tetraoxide (0s 0) is obtained4) The gaseous oxidation mixture of (a). The oxidized gaseous mixture was then melted in cooled potassium hydroxide solution (KOH) to form K2[ OsO ]4(OH)2]And eliminates the interference of Ir impurities. Finally adding NaHS into the solution to precipitate OsS2Obtaining OsS by drying treatment2And (3) powder.
Further, in the spherical molding and shaping step, the dried OsS obtained in the radioactive substance preparation step is used2Mixing the powder with a high molecular adhesive, then placing the mixture in a forming container with low radiation absorptivity to form solid pellets, and finally obtaining the radioactive source required by the in vivo imaging capsule imaging.
Furthermore, the capsule detector array at least comprises an X-ray detection array, a Compton back scattering detection array, a driving shaft, a signal acquisition device and a detector array signal output line. The driving shaft is arranged between the rear end bottom plate and the front end radioactive source shielding bottom plate and is respectively connected with the capsule electronic system and the front end transmission interface, and the front end transmission interface is connected with the rotary driving interface of the front end radioactive source shielding bottom plate. The X-ray detection array and the Compton back scattering detection array are respectively composed of an X-ray detector and a Compton back scattering detector. The X-ray detector and the Compton back scattering detector are alternately distributed around the signal acquisition device at equal intervals along the circumferential direction and are respectively used for receiving photons which are reflected by the intestinal wall and the intestinal contents and are generated due to the X fluorescence effect and the Compton back scattering effect. The signal acquisition device consists of an X-ray signal processing module and a Compton photon counting module. The signal acquisition device is connected with the detector array signal output line, and transmits the acquired signals to the capsule electronic system through the detector array signal output line. Meanwhile, the signal acquisition device surrounds the driving shaft and is fixed on a rear end bottom plate and a front end radioactive source shielding bottom plate of the driving shaft.
Furthermore, the capsule electronic system at least comprises a signal processing module, a signal transmitting device and a signal input interface. The signal input interface is connected with the signal acquisition device through the detector array signal output line so as to receive the attenuation signal acquired by the signal acquisition device. And the signal processing module is used for reconstructing the acquired attenuation signals into image signals. The signal transmitting device communicates with the extracorporeal signal transceiving device through a high-frequency signal, so that data such as capsule images, positions and paths are transmitted.
Further, the capsule battery pack is positioned behind the detector array, surrounds the periphery of the capsule battery pack and consists of rechargeable lithium batteries. The capsule battery pack provides power required by operation for the detector array, the capsule electronic system and the capsule central control system through power lines.
Furthermore, the capsule central control system at least comprises a three-axis accelerometer, a three-axis magnetometer, a rotating motor and a central control circuit. The rotating motor is positioned at the front end of the capsule electronic system and connected with the driving shaft to drive the driving shaft so as to drive the front end of the radioactive source group to rotate at a constant speed. The three-axis accelerometer and the three-axis magnetometer are fixed on the central control circuit, are respectively used for measuring the position of the capsule and the advancing path, and are connected with the signal transmitting device through signal transmission lines.
Furthermore, the external signal transceiver is adhered to the back of the patient and connected with an external image processing system in a wired or wireless connection mode, so that data can be transmitted and intestinal tract three-dimensional drawing imaging can be performed.
Specifically, the external signal transceiver at least comprises a positioning system, a control system, a data recording system and a wireless transmission device system. The positioning system is used for acquiring the position and path information of the in-vivo capsule imaging system, the control system is used for controlling the in-vivo capsule imaging system to acquire images, and the data recording system is used for recording data transmitted back by the in-vivo capsule imaging system. The wireless transmission device is distributed in the three systems and is communicated with the capsule electronic system in the in-vivo imaging capsule.
Further, the external wireless charging device is connected with the external signal transceiver during use and is attached to the back of a patient, so that the electric quantity of the internal imaging capsule is detected and the internal imaging capsule is wirelessly charged in a non-contact manner.
Specifically, the external wireless charging device is composed of a power line, a signal transmission line, a wireless charging panel, a wireless charging field emitter and an electric quantity display device. The wireless charging field emitter is arranged in the wireless charging panel, and the power line and the signal transmission line are arranged at the tail end of the charging panel. The external wireless charging device can provide a non-contact wireless charging function, and the external wireless charging plate is fixed on the back of the patient when necessary, so that the non-contact wireless charging is carried out on the internal imaging capsule, and the cruising ability of the internal imaging capsule is further ensured. Meanwhile, the signal transmission line is connected with the in-vitro signal transceiver to acquire the electric quantity condition of the in-vivo imaging capsule, so that the electric quantity condition is displayed through the electric quantity display device and the charging process is monitored.
Further, the in-vitro image processing system comprises a path tracking module, an intestinal wall reconstruction module, a quantitative measurement module and an auxiliary detection module. The path tracking module may display a completed path of the in vivo imaging capsule, and the intestinal wall reconstruction module may be capable of displaying the anatomy of the intestinal inner wall in three dimensions. The quantitative measurement module can quantitatively measure and mark the size, the volume and the cross-sectional area of the intestinal tract tissue structure. The auxiliary detection module can automatically analyze all intestinal tract scanning data and mark a suspected lesion area.
Further, still include external wireless charging device, external wireless charging device comprises power cord, signal transmission line, wireless charging panel, wireless field transmitter and electric quantity display device of charging at least, wireless field transmitter of charging is arranged in wireless charging panel, and electric quantity display device is located directly over wireless charging panel, and the current situation of charging is observed to accessible electric quantity display device. The wireless charging panel tail end is arranged in to power cord and signal transmission line, signal transmission line one end is connected with external signal transceiver, acquires the electric quantity condition of present internal formation of image capsule, the signal transmission line other end passes through electric quantity display device bottom interface and wireless charging field transmitter interface, links to each other electric quantity display device and wireless charging field transmitter to pass through electric quantity display device carries out real-time display and monitors the charging process to the electric quantity condition. The power cord enters from the bottom end of the external wireless charging device and is connected with the wireless charging field emitter to provide electric energy for the device.
The utility model has the advantages that:
1) the utility model discloses imaging system, internal formation of image part adopt integrative microcapsule structural design, and internal formation of image capsule is small, and the closure is good. The intestinal tract detection is carried out in a manner that the patient swallows the intestinal tract detection, so that the operation difficulty of a doctor is greatly reduced. And the traditional Chinese medicine composition has no adverse reaction after being swallowed, thereby greatly reducing the burden of the patient in the mind and body and simultaneously greatly shortening the enteroscopy period. And meanwhile, the disposable disinfection device is safe and reliable due to the disposable characteristic, and the disinfection potential safety hazard is greatly reduced.
2) The mode of collecting signals by matching a low-dose multi-axial small spherical radioactive source with a contrast agent is adopted, so that the radiation dose received by a patient in the detection process is extremely low. Meanwhile, the small spherical radioactive source wrapped by the low-emissivity high polymer can provide a radiation source with proper strength, good stability and stable half-life period, so that the time length and quality of signal acquisition can be ensured. And finally, due to the design of the multi-axis radioactive source, the detection angle is guaranteed, and the complete intestinal cross section can be detected.
3) The detector array of the in vivo imaging capsule consists of an X-ray detection array and a Compton backscatter detection array. The detectors in the array are arranged in an equal interval alternating mode, are fixed in the middle of the capsule around the driving shaft and are respectively used for collecting photons generated by an X fluorescence effect and a Compton back-radiation effect. The different action modes of the fluorescence effect on the Compton back-radiation effect and the intestinal contents are utilized, and the difference of photon counting is utilized to distinguish the intestinal wall from the intestinal contents, so that the anatomical structure of the intestinal wall is accurately positioned. Intestinal tract cleaning is not needed, and the influence of intestinal tract contents on the accuracy of a detection result is small.
4) The utility model discloses X line capsule 3D endoscope system adopts external signal transceiver. The external signal transceiver is attached to the back of a patient until an internal imaging capsule is removed, the patient can live normally, and compared with a traditional enteroscope, the influence of the whole detection process on the normal life of the patient is small.
5) Through the cooperation of the triaxial accelerometer, the triaxial magnetometer, the triaxial radioactive source and the rotating shaft, the in-vivo imaging capsule detects the intestinal wall in each direction and reflects the traveling path of the capsule in the body in real time. Accurate three-dimensional structure information and path information are provided for doctors, so that the whole detection process is visualized, and the probability of intestinal hemorrhage and intestinal perforation in the resection operation is greatly reduced.
6) By adopting the non-contact wireless charging system, the service condition of the electric quantity of the in-vivo imaging capsule can be detected in real time, and the in-vivo imaging capsule is wirelessly charged in a non-contact mode. This charging mode can provide longer time of endurance for the internal formation of image capsule, ensures the long-time imaging demand.
7) The in-vitro image processing system provides a quantitative sectional measuring tool, can carry out quantitative analysis on a specific focus according to the requirements of doctors, and provides accurate quantitative indexes. Meanwhile, an auxiliary detection system is provided to mark potential lesion areas, so that the workload of doctors is reduced, and misdiagnosis caused by fatigue is reduced.
Drawings
The present invention will be further explained with reference to the drawings and examples.
Fig. 1 is a schematic structural diagram of a system according to a preferred embodiment of the present invention.
FIG. 2 is a schematic view of the present invention in use;
fig. 3 is a schematic diagram of the overall structure of the in vivo imaging capsule of the present invention.
Fig. 4 is a schematic structural view of the radiation source set of the in vivo imaging capsule of the present invention.
Fig. 5 is a schematic diagram of the explosion structure of the in vivo imaging capsule of the present invention.
Fig. 6 is a schematic diagram of the arrangement of the external signal transceiver and the external wireless charging device according to the present invention.
Fig. 7 is a schematic structural diagram of the external wireless charging device of the present invention.
Fig. 8 is a schematic diagram of the system of the present invention.
In the figure: 1. an in vivo imaging capsule, 2, an in vitro signal transceiver, 3, an in vitro image processing system, 4, a radioactive source shielding shell, 5, a capsule shell, 6, an opening, 7, a detector array, 8, a capsule electronic system, 9, a capsule central control system, 10, a capsule battery pack, 11, a front half part of the capsule shell, 12, a radioactive source collimator, 13, radioactive substances, 14, a radioactive source container, 15, a radioactive source rotating shaft, 23, a driving shaft, 24, a front radioactive source shielding bottom plate, 25, an X-ray detection array, 26, a Compton back scattering detection array, 27, a radioactive source group, 28, a rear bottom plate, 29, a rear half part of the capsule shell, 30, a signal acquisition device, 31, a positioning system, 32, a data recording system, 33, an in vitro wireless charging device, 34, a control system, 35, a power display device, 36, a wireless charging plate, 37, Power lines, 38, signal transmission lines, 39, wireless charging field transmitter.
Detailed Description
Although the present invention has been disclosed in the preferred embodiments, it is not intended to limit the present invention, and any person skilled in the art can use the above-mentioned method and technical contents to make possible changes and modifications to the technical solution of the present invention without departing from the spirit and scope of the present invention, therefore, any simple modification, equivalent changes and modifications made to the above embodiments by the technical substance of the present invention all belong to the protection scope of the technical solution of the present invention.
The present invention will now be described in detail with reference to the accompanying drawings. This figure is a simplified schematic diagram, and merely illustrates the basic structure of the present invention in a schematic manner, and therefore it shows only the constitution related to the present invention.
The utility model discloses in view of current colorectal mirror system bulky, external equipment is many, the inspection is prepared duration cycle long, the operation difficulty, to patient normal life influence great and have the puncture hemorrhage scheduling problem. An X-ray capsule 3D endoscope system is provided. The above problems are effectively solved by swallowing the in vivo imaging capsule 1 in combination with a contrast agent, an in vitro signal transceiver and an image processing system.
As shown in fig. 1 and fig. 2, the X-ray capsule 3D endoscope system of the present invention includes an in-vivo imaging capsule 1, an in-vitro signal transceiver 2, an in-vitro wireless charging device 33, and an in-vitro image processing system 3. The in vivo imaging capsule 1 is a disposable device and is communicated with the reusable in vitro signal transceiver 2 through a high-frequency wireless signal, and the reusable in vitro image processing system 3 controls the in vitro signal transceiver 2 through a wired or wireless mode, so that the in vivo imaging capsule 1 is controlled. In this embodiment, it is preferable that USB is used for data transmission between the external wireless charging device 33 and the external signal transceiver 2, and between the external signal transceiver 2 and the external image processing system 3.
As shown in fig. 3, the in-vivo imaging capsule 1 includes a radiation source group 27, a detector array 7, a capsule battery group 10, a capsule electronic system 8 and a capsule central control system 9 which are arranged inside a capsule housing 5. The radioactive source group 27 is arranged at the head of the hemisphere of the front half part 11 of the capsule shell and is isolated from the capsule detector array 7 in the middle part by a radioactive source shielding bottom plate 24 at the front end. The capsule electronic system 8 surrounds the periphery of the capsule battery pack 10, and the capsule central control system 9 is positioned at the rear part of the capsule battery pack 10 and is arranged in the rear half part 29 of the capsule shell. The capsule electronic system 8 is wrapped around the periphery of the capsule battery pack 10, thereby further reducing the capsule size.
As shown in fig. 4, in the present embodiment, three radiation source collimators 12 are taken as an example for explanation, and the radiation source group 27 includes one radiation source container 14, three radiation source collimators 12, a radioactive substance 13, a radiation source rotating shaft 15, a front end radiation source shielding bottom plate 24, a front end fixing device, and a radiation source shielding housing 4. The radioactive source collimators 12 are disposed at equal intervals and at equal heights on the side of the radioactive source container 14, and the radioactive material 13 is disposed in the radioactive source container 14. The tail end of the radioactive source rotating shaft 15 is fixed on the front radioactive source shielding bottom plate 24 and is connected with a rotating driving interface of the front radioactive source shielding bottom plate 24, and the front end of the radioactive source rotating shaft is connected with the tail end of the radioactive source container 14 to drive the radioactive source container 14 to rotate. The front radioactive source shielding backplane 24 isolates the capsule detector array 7 from the radiation source array 27. The radioactive source group 27 is isolated from the front half part 11 of the capsule shell by the radioactive source shielding shell 4, three openings 6 are arranged at the positions of the radioactive source shielding shell 4 corresponding to the radioactive source collimator 12, and the tail end of the radioactive source collimator 12 is fixed at the openings 6 of the radioactive source shielding shell 4 so as to irradiate the intestinal wall by rays. The front end fixing means fixes the radiation source unit 27 inside the capsule housing 5. Meanwhile, the radioactive substance 13 in the in-vivo imaging capsule 1 is made into a globular solid by powder with radioactivity or made into a globular solid by infiltrating the radioactive substance 13 with a porous substance with adsorption capacity. Meanwhile, the half-life period of the radioactive pellets is at least 4-5 days, so that enough imaging radioactive sources are provided in the period of being discharged out of the body through the intestinal tract. Before the X-ray capsule 3D endoscope system is used, a patient needs to swallow a small amount of intestinal canal wall contrast agent and the in-vivo imaging capsule 1, the in-vivo imaging capsule 1 is detected by the in-vitro signal device to reach a designated position and then starts imaging, and finally the in-vivo capsule is discharged out of the body along with excrement through an intestinal tract.
As shown in FIG. 5, the capsule detector array 7 is composed of an X-ray detection array 25, a Compton backscatter detection array, a drive shaft 23, a signal acquisition device 30 and a detector array signal output line. The driving shaft 23 is installed between the rear end bottom plate 28 and the front end radioactive source shielding bottom plate 24, and is respectively connected with the capsule electronic system 8 and the front end transmission interface, and the front end transmission interface is connected with the rotation driving interface of the front end radioactive source shielding bottom plate 24. The X-ray detection array 25 and the compton backscatter detection array are composed of an X-ray detector and a compton backscatter detector, respectively. The X-ray detector and the compton backscatter detector are alternately distributed around the signal acquisition device 30 at equal intervals, and are respectively used for receiving photons reflected by the intestinal wall and the intestinal contents and generated due to the X-fluorescence effect and the compton backscatter effect. The signal acquisition device 30 is composed of an X-ray signal processing module and a compton photon counting module. The signal acquisition device 30 is connected to the detector array signal output line, and transmits the acquired signal to the capsule electronic system 8 through the detector array signal output line. Meanwhile, the signal acquisition device 30 surrounds the driving shaft 23 and is fixed on the rear end bottom plate 28 and the front end radioactive source shielding bottom plate 24 of the driving shaft 23.
As shown in fig. 6, the external signal transceiver 2 is composed of a positioning system 31, a control system 34, a data recording system 32 and a wireless transmission device. The positioning system 31 is configured to acquire position and path information of the in-vivo capsule imaging system, the control system 34 is configured to control the in-vivo capsule imaging system to perform image acquisition, and the data recording system 32 is configured to record data transmitted back by the in-vivo capsule imaging system. The wireless transmission devices are distributed in the three systems and communicate with the capsule electronic system 8 in the in vivo capsule imaging system. The capsule is attached to the back of a patient and continuously communicates with the in-vivo imaging capsule 1, so that the specific position of the capsule is positioned, imaging signals are collected, and a capsule traveling path is drawn. In this embodiment, the control system 34 adopts an SR3 type control system developed by maurian, and is composed of a communication module, a positioning control module, and a data transmission module. And the data acquisition and transmission device is respectively used for controlling the data recording system to acquire and receive in-vivo capsule return data, sending a position acquisition instruction to the positioning system, and collecting and transmitting return data of the control system and the data recording system to the in-vitro image processing device. The data recording system 32, which employs a DataNet data processing system, may collect image data returned by the in vivo imaging capsule and transmit the data to the control system. The positioning system 31 adopts an autonomously developed S-TRACK system, integrates the functions of positioning, recording and data transmission, and can calculate and transmit the specific position of the current in-vivo imaging capsule in real time through a self-adaptive path function. The wireless transmission device adopts a multi-channel wireless data acquisition and transmission technology, the wireless transmission devices positioned in the positioning system 31 and the data recording system 32 can transmit data to the control system through the wireless transmission devices positioned in the control system, the control system integrates and packages the data, and then the data is transmitted to the in-vitro image processing system 3 through the wireless transmission devices.
As shown in fig. 7, the in-vitro wireless charging device 33 is composed of a power line 37, a signal transmission line 38, a wireless charging board 36, a wireless charging field emitter 39 and a power display device 35, wherein the wireless charging field emitter 39 is disposed in the wireless charging board 36, the power display device 35 is disposed right above the wireless charging board 36, and the current charging situation can be observed through the power display device 35. The power line 37 and the signal transmission line 38 are arranged at the tail end of the wireless charging plate 36, one end of the signal transmission line 38 is connected with the external signal transceiver 2 to obtain the electric quantity condition of the current internal imaging capsule 1, and the other end of the signal transmission line is connected with the wireless charging field emitter 39 through the interface at the bottom end of the electric quantity display device 35 to connect the electric quantity display device 35 with the wireless charging field emitter 39, so that the electric quantity condition is displayed in real time through the electric quantity display device 35 and the charging process is monitored. A power cord 37 enters from the bottom end of the in vitro wireless charging device 33 and connects to a wireless charging field transmitter 39 to provide power to the device.
When in use, the external wireless charging device 33 is attached to the back of a human body to wirelessly charge the internal imaging adhesive in a non-contact manner. In one embodiment, a TesLink contactless wireless charging system from Gill Electronics is used. The wireless charging field transmitter 39 of the system can be attached to the back of a patient, the wireless charging field transmitter 39 excites a wireless charging field, the wireless charging field can penetrate the skin and tissue of the patient, and the in-vivo imaging capsule 1 is imaged in a non-contact mode. Meanwhile, the wireless charging device can be connected with the in-vitro signal transceiver 2 in a wired connection mode during use, so that the current electric quantity data of the in-vivo imaging capsule 1 can be acquired in real time, and the charging process can be tracked and monitored.
The in-vitro image processing system 3 comprises a path tracking module, an intestinal wall reconstruction module, a quantitative measurement module and an auxiliary detection module. The path tracking module may display a completed path of the in vivo imaging capsule 1, and the intestinal wall reconstruction module may be capable of displaying the anatomy of the intestinal inner wall in three dimensions. The quantitative measurement module can quantitatively measure and mark the size, the volume and the cross-sectional area of the intestinal tract tissue structure. The auxiliary detection module can automatically analyze all intestinal tract scanning data and mark a suspected lesion area.
As shown in fig. 8, the in-vitro signal transceiver 2 monitors the in-vivo capsule traveling route in real time, and when the in-vitro signal transceiver reaches a to-be-monitored site, the in-vitro image processing system 3 sends an image acquisition command to the in-vitro signal transceiver 2 in a wired connection manner. The in vitro signal transceiver 2 communicates with the in vivo imaging capsule electronic system 8 through a wireless high-frequency signal, and the capsule electronic system 8 controls the detector array 7 to collect and integrate image signals. The image signal is transmitted to the capsule electronic system 8 through the signal line and is transmitted to the in-vitro signal transceiver 2 through the high-frequency signal again, so that the three-dimensional drawing and display of the intestinal wall in the in-vitro image processing system 3 are realized.
In light of the foregoing, it will be apparent to those skilled in the art from this disclosure that various changes and modifications can be made without departing from the scope of the invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.
Claims (10)
1. An X-ray capsule 3D endoscope system characterized by: the in-vivo imaging device comprises an in-vivo imaging capsule, an in-vitro signal transceiver and an in-vitro image processing system, wherein the in-vitro signal transceiver is communicated with the in-vivo imaging capsule in a wireless mode; the in-vitro image processing system is connected with the in-vitro signal receiving and sending device in a wired or wireless mode and sends a control command to the capsule electronic system through the in-vitro signal receiving and sending device; the in-vivo imaging capsule is used for emitting radiation beams, detecting attenuation signals generated by reflection of intestinal walls and intestinal contents and transmitting the attenuation signals to the in-vitro signal transceiver; the in-vitro signal transceiver is used for transmitting the received attenuation signal to the in-vitro image processing system; the in-vitro image processing system is used for carrying out post-processing on the image signals collected by the in-vivo imaging capsule.
2. The X-ray capsule 3D endoscopic system of claim 1, wherein: the in-vivo imaging capsule comprises a radiation source group, a detector array, a capsule battery pack, a capsule central control system and a capsule electronic system which are sequentially arranged in a capsule shell from front to back, wherein the radiation source group is isolated from the detector array through a front end radiation source shielding bottom plate; the capsule battery pack is positioned behind the detector array, the capsule electronic system surrounds the periphery of the capsule battery pack, and the capsule electronic system is isolated from the detector array through a rear end bottom plate; the capsule central control system is positioned at the rear part of the capsule battery pack and is arranged in the rear half part of the capsule shell; the capsule battery pack provides power supply required by operation for the detector array, the capsule electronic system and the capsule central control system through power lines.
3. The X-ray capsule 3D endoscopic system of claim 2, wherein: the radioactive source group comprises radioactive source shielding shells, radioactive source containers, radioactive source collimators, radioactive substances, radioactive source rotating shafts and front end fixing devices, wherein the number of the radioactive source collimators is at least three, and the radioactive source collimators are arranged on the side surfaces of the radioactive source containers at equal intervals in a radial shape along the circumferential direction; the radioactive substance is placed in the radioactive source container; the tail end of the radioactive source rotating shaft is fixed on the front radioactive source shielding bottom plate and is connected with the rotary driving interface of the front radioactive source shielding bottom plate, and the front end of the radioactive source rotating shaft is connected with the tail end of a radioactive source container to drive the radioactive source container to rotate; the radioactive source shielding shell covers the outer side of the radioactive source group to isolate the radioactive source group from the capsule shell, the radioactive source shielding shell is provided with openings with the same number as the radioactive source collimators corresponding to the radioactive source collimators, and the tail ends of the radioactive source collimators are fixed at the openings of the radioactive source shielding shell so as to irradiate the intestinal wall with rays; the front end fixing device fixes the radiation source group in the capsule shell.
4. The X-ray capsule 3D endoscopic system of claim 3 wherein: the radioactive substance is a radioactive pellet which is a small pellet solid made of radioactive powder or a small pellet solid made of porous substance with adsorption capacity and infiltrated with the radioactive substance; the outer layer of the radioactive pellet is coated with high molecular polymer with low radiation absorptivity; the half-life of the radioactive pellet is at least 4-5 days.
5. The X-ray capsule 3D endoscopic system of claim 2, wherein: the detector array at least comprises an X-ray detection array, a Compton back scattering detection array, a driving shaft, a signal acquisition device and a detector array signal output line, wherein the driving shaft is arranged between a rear end baseplate and a front end radioactive source shielding baseplate and is respectively connected with the capsule electronic system and a front end transmission interface, and the front end transmission interface is connected with a rotary driving interface of the front end radioactive source shielding baseplate; the X-ray detection array and the Compton back scattering detection array are respectively composed of an X-ray detector and a Compton back scattering detector, and the X-ray detector and the Compton back scattering detector are alternately distributed around the signal acquisition device at equal intervals along the circumferential direction and are respectively used for receiving photons reflected by the intestinal wall and the intestinal contents and generated due to an X fluorescence effect and a Compton back scattering effect; the signal acquisition device is connected with the detector array signal output line and transmits the acquired signal to the capsule electronic system through the detector array signal output line; and the signal acquisition device surrounds the driving shaft and is fixed on the rear end bottom plate and the front end radioactive source shielding bottom plate of the driving shaft.
6. The X-ray capsule 3D endoscopic system of claim 5, wherein: the capsule electronic system at least comprises a signal processing module, a signal transmitting device and a signal input interface, wherein the signal input interface is connected with the signal acquisition device through a signal output line of the detector array so as to receive an attenuation signal acquired by the signal acquisition device; the signal processing module is connected with the signal input interface and used for reconstructing the acquired attenuation signal into an image signal; the signal transmitting device receives the signal of the signal processing module and communicates with the extracorporeal signal receiving and transmitting device through a high-frequency signal, so that capsule image, position and path data are transmitted.
7. The X-ray capsule 3D endoscopic system of claim 6, wherein: the capsule central control system at least comprises a three-axis accelerometer, a three-axis magnetometer, a rotating motor and a central control circuit, wherein the rotating motor is positioned at the front end of the capsule electronic system, is connected with the driving shaft and is used for driving the driving shaft to drive the front-end radiation source group to rotate at a constant speed; the three-axis accelerometer and the three-axis magnetometer are fixed on the central control circuit, are respectively used for measuring the position and the advancing route of the capsule, and are connected with the signal transmitting device through signal transmission lines.
8. The X-ray capsule 3D endoscopic system of claim 1, wherein: the in-vitro signal transceiver at least comprises a positioning system, a control system, a data recording system and a wireless transmission device, wherein the positioning system is used for acquiring the position and path information of the in-vivo imaging capsule, the control system is used for controlling the in-vivo imaging capsule to acquire images, and the data recording system is used for recording data transmitted back by the in-vivo imaging capsule; the wireless transmission device is distributed in a positioning system, a control system and a data recording system and is communicated with the capsule electronic system.
9. The X-ray capsule 3D endoscopic system of claim 1, wherein: the in-vitro image processing system comprises a path tracking module, an intestinal wall reconstruction module, a quantitative measurement module and an auxiliary detection module, wherein the path tracking module is used for displaying the complete path of the in-vivo imaging capsule; the intestinal wall reconstruction module is used for displaying an anatomical structure of a three-dimensional intestinal inner wall; the quantitative measurement module is used for quantitatively measuring and marking the size, the volume and the cross-sectional area of the intestinal tract tissue structure; the auxiliary detection module is used for automatically analyzing all intestinal tract scanning data and marking a suspected lesion area.
10. The X-ray capsule 3D endoscopic system of claim 1, wherein: still include external wireless charging device, external wireless charging device comprises power cord, signal transmission line, wireless charging panel, wireless charging field transmitter and electric quantity display device at least, wireless charging field transmitter arranges wireless charging panel in, and electric quantity display device is located directly over the wireless charging panel, the power cord is arranged wireless charging panel tail end in with signal transmission line, signal transmission line one end is connected with external signal transceiver, acquires the electric quantity condition of current internal formation of image capsule, the signal transmission line other end passes through electric quantity display device bottom interface and wireless charging field transmitter interface, links to each other electric quantity display device and wireless charging field transmitter, and the power cord gets into from external wireless charging device bottom and links to each other with wireless charging field transmitter.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110025284A (en) * | 2019-04-04 | 2019-07-19 | 南京速瑞医疗科技有限公司 | A kind of x-ray capsule 3D endoscopic system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025284A (en) * | 2019-04-04 | 2019-07-19 | 南京速瑞医疗科技有限公司 | A kind of x-ray capsule 3D endoscopic system |
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