CN118873832A - Bionic heart pulsating pump during extracorporeal circulation and artificial intelligent monitoring system - Google Patents
Bionic heart pulsating pump during extracorporeal circulation and artificial intelligent monitoring system Download PDFInfo
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Abstract
The invention discloses a bionic heart pulsating pump and an artificial intelligent monitoring system during extracorporeal circulation, which comprises a bionic pulsating pump base, wherein a bionic heart pulsating pump main body, a first electromagnetic piston extrusion column group and a second electromagnetic piston extrusion column group are fixed on the bionic pulsating pump base, the bionic heart pulsating pump main body consists of a blood input tube, a pulsating sac-room, a room valve connecting tube, a pulsating sac-room and a room valve connecting tube, and the artificial intelligent monitoring system comprises an information acquisition assembly and a monitoring system host. The bionic heart pulsating pump main body can imitate the functions of a room (A) room (V) and heart valves of a human heart, adopts the natural property of a composition material, namely elasticity, as main driving force and secondary driving force, as dual driving of extracorporeal circulation flow, realizes the control of the flow and the frequency through a monitoring and control system, and can be used once to avoid cross infection, and the disposable and integrated pulsating perfusion bag can be used immediately after being opened.
Description
Technical Field
The invention relates to the technical field of bionic heart pulsatile pumps, in particular to a bionic heart pulsatile pump during extracorporeal circulation and an artificial intelligent monitoring system.
Background
Extracorporeal circulation (Cardiopulmonary Bypass, CPB) is a guarantee and necessity for cardiovascular surgery, and its forms of perfusion are divided into pulsatile Perfusion (PF), a well-known way of organ protection, and non-pulsatile perfusion (NPF), which is a way of more closely approximating the natural flow of blood in the body. The circulatory system of the human body is pulsed as the heart contracts and expands to push blood through arteries and veins. NPF is still the most popular perfusion mode, which is produced by rolling and centrifugal pumps by default, and advection perfusion is a stable, continuous flow of blood that does not mimic the natural pulsatile blood flow of the human body. May lead to certain complications such as vascular paralysis syndrome and lung and kidney damage. Another alternative is to mimic the arterial pulse produced by the heart, which some people consider more physiological.
Studies have demonstrated that PF may be beneficial for post-operative recovery in CPB patients, who are better in terms of hospitalization time and recovery rate than patients receiving advection. Despite the lack of reliable evidence of a long lasting positive effect, guidelines of the european cardiothoracic surgery association/european cardiothoracic anesthesia association/european cardiovascular perfusion committee in 2019 for adult cardiac surgery CPB suggest that pulsatile perfusion (type IIa, evidence level B) may be considered for high risk patients with negative lung and kidney prognosis.
Conventionally, pulsatility is defined by the difference between the maximum systolic pressure and the minimum diastolic pressure. This simple formula, while generally applicable to measurement of pulsatility, is not sufficient to represent hemodynamic energy associated with pulsatile perfusion modes, as the formation of PF depends on energy gradients, not just pressure or flow gradients.
Energy Equivalent Pressure (EEP) is a proposed measurement method to reflect the difference between advection and pulsatile perfusion. It is based on the relationship of the area under the hemodynamic power curve to the area under the pump flow curve. The difference between EEP and Mean Arterial Pressure (MAP), i.e., the difference between pulsatile and non-pulsatile waveforms with the same mean pressure and flow, is referred to as residual hemodynamic energy (SHE). EEP should be higher than MAP; however, for a complete NPF, these values are equal.
At present, PF is realized by two modes, namely an extracorporeal circulation machine rolling pump and a special pulsating pump and an intra-aortic balloon pump (IABPs) which generate pulsation, but the PF has the defects. The clinical effect of the former has long been theorized that CPB line elements suppress SHE levels up to 80% due to consumption of circulating line hardware, and are essentially ineffective; many data supporting PF comes from studies in CPB using pulsatile pumps and IABP to generate pulsations. It is uncertain whether this shows a particular benefit for a particular patient population, or whether the IABP provides adequate levels of SHE, benefits that can be observed clinically. SHE produced significantly higher than the pump was producing pulsations, which could explain its improved outcome. IABP can prevent energy loss and is not suitable for low risk patients to beat during CPB because of its 50% complication rate. Because the system providing electrocardiographic gated pulsations is not suitable for the cardioplegic phase of cardiac surgery, it may also be beneficial immediately after opening the aorta or as a post-operative cardiotonic aid in the most ill patients.
At present, PF is realized by two modes, namely an extracorporeal circulation machine rolling pump and a pulsating pump and an aortic internal balloon pump (IABPs) which are used for generating pulsation, but the PF has the defects; there are obvious limitations in clinical applications, and it is therefore urgent and beneficial to explore a new pulsatile perfusion device.
Disclosure of Invention
Based on the technical problems in the background technology, the invention provides a bionic heart pulsating pump during extracorporeal circulation and an artificial intelligent monitoring system.
The invention provides a bionic heart pulsating pump during extracorporeal circulation, which comprises a bionic pulsating pump base, wherein a bionic heart pulsating pump main body, a first electromagnetic piston extrusion column group and a second electromagnetic piston extrusion column group are fixed on the bionic pulsating pump base, and the bionic heart pulsating pump main body consists of a blood input pipe, a pulsating sac-room, a room valve connecting pipe, a pulsating sac-room and a room valve connecting pipe;
The blood input end, the pulsation sac-room, the room valve connecting pipe, the pulsation sac-room and the room valve connecting pipe are sequentially communicated, a flowmeter connecting port is arranged at the rear side of the blood input end, two pulsation sac-room pressure measuring connecting ports are arranged on the room valve connecting pipe, and a pulsation sac-room pressure measuring connecting port is arranged on the room valve connecting pipe;
The first electromagnetic piston extrusion column group is arranged in the position of the bionic pulsating pump base positioned in the room valve connecting pipe, and the second electromagnetic piston extrusion column group is arranged in the position of the bionic pulsating pump base positioned in the room valve connecting pipe;
The pulsation sac-room and the pulsation sac-room comprise a strong elastic steel wire mesh cover, a rubber pulsation sac and a biological membrane which are arranged from outside to inside;
the blood input end is connected with the arterial end of the extracorporeal circulation machine, and the ventricular valve connecting pipe is connected with the aortic inserting end.
Preferably, the bionic pulsating pump base is sequentially provided with a first placing groove and a second placing groove, the pulsating sac-room is arranged in the first placing groove, and the pulsating sac-room is arranged in the second placing groove.
Preferably, the blood input end and the ventricular valve connecting pipe are arranged on the bionic pulsating pump base through a fixed bracket.
The invention provides an artificial intelligent monitoring system of a bionic heart pulsating pump during extracorporeal circulation, which comprises an information acquisition component and a monitoring system host, wherein the information acquisition component comprises a flowmeter, two pulsating sac-room pressure measuring sensors and a pulsating sac-room pressure measuring sensor.
Preferably, the two pulsating bag-room pressure measuring sensors are respectively connected to the two pulsating bag-room pressure measuring connectors, the pulsating bag-room output pressure measuring sensor is connected to the pulsating bag-room output pressure measuring connector, and the flowmeter is connected to the flowmeter connector.
Preferably, the information output ends of the flowmeter, the two pulsating sac-atrioventricular pressure sensors and the pulsating sac-atrioventricular output pressure sensor are respectively connected with the signal input end of the monitoring system host through signal wires, and the signal output end of the monitoring system host is connected with the first electromagnetic piston extrusion column group and the second electromagnetic piston extrusion column group through signal wires.
The beneficial effects of the invention are as follows:
1. Bionic heart pulsatile pump body: the shape of the expanded pulsating bag is in a spindle shape design, and the pulsating bag imitates the functions of a room (A) chamber (V) and heart valves of a human heart, can generate pulsating blood flow, is similar to or approximate to the physiology of normal heart operation, and is beneficial to the perfusion of viscera and microcirculation; the material adopts and has good biocompatibility material to make, this pulsation energy source is realized through the autonomous pulsation of extracorporeal circulation organization notes flow and pulsation perfusion bag, pulsation bag wall divides inlayer, middle level and skin, the inlayer is the biomembrane, can protect blood, the middle level is for having good elasticity and high compliance rubber layer, the skin is many strong elasticity wire cover, supplementary the shrink of the pulsating bag of rubber, well outer layer structure's elasticity and compliance are the pulsation energy, produce surplus hemodynamic energy, room inter-bag junction and room bag export simulation mitral valve and aortic valve mouth, the temperature is invariable: the non-mechanical work, the electromagnetic work and the like do not generate heat, and the cooling treatment is not needed;
2. the driving mode is as follows: the current common driving modes of the blood pump are pneumatic, hydraulic, motor driving, electromagnetic driving and the like, and the gas and liquid driving needs external gas and liquid sources, so that the volume is large; the motor drive is easy to cause hemolysis due to the fact that the whole process outputs rigid driving force, along with the development of electromagnetic technology, the electromagnetic drive is applied to the field of blood pumps, and the electromagnetic induction heating problem exists, the driving mode of the device is two, namely, the natural attribute of the component materials, namely, the elasticity is mainly driven, the secondary driving force is the extracorporeal circulation flow, and the defects of pneumatic, hydraulic, motor drive and electromagnetic drive are avoided;
3. The pulse perfusion frequency and the stroke volume are adjustable and accord with human physiology: the functions are realized by a monitoring and control system, the modes of a heart paralysis stage and a heart beating stage are divided, the information sources are the flow (V, ml/min) of an external circulation machine and the expansion final volume (correction value after treatment of the three) of a monitoring beating capsule, the initial Stroke Volume (SV) and the frequency (HR) are set according to the flow, the stroke volume is determined by the volume of the beating capsule, the volume is determined by the pressure monitored by the monitoring system (volume-pressure, physical measurement), the frequency is realized by the control system, and the setting frequency is based on the heart rate of a normal person as a reference; when the heart resumes beating, the monitoring system collects the cardiogram to form synchronous beating;
4. the pulsating perfusion flow is synchronous with the rotational flow of the extracorporeal circulation machine: the function is realized by a monitoring and control system, the information source is the flow of the extracorporeal circulation machine, the initial stroke volume and frequency are set according to the flow, after the initial stroke volume and frequency are operated, the stroke volume and frequency are adjusted manually and intelligently (finally, the room volume is reached), the optimized normal basic physiological heart function parameters (pulse waves) are achieved, and the total output or stroke flow is the same as the flow of the extracorporeal circulation machine;
5. Artificial intelligent monitoring: monitoring parameters: the extracorporeal circulation flow, the intra-atrial pressure, the intra-ventricular pressure, the room volume, the stroke volume, the pulse frequency and the output pressure form data parameters, which is beneficial to clinical research and summarization;
6. disposable, integrated pulsating perfusion bag: disposable, which avoids cross infection, and can be used immediately after being opened;
7. Extended use: the improved structure can be used for an ECMO terminal, and the improved structure is possibly used for left heart diversion or temporary artificial heart and has an early warning function.
Drawings
FIG. 1 is a schematic diagram of a bionic heart pulsatile pump and an artificial intelligence monitoring system during extracorporeal circulation according to the present invention;
FIG. 2 is a schematic diagram of the main structure of a bionic heart pump during extracorporeal circulation and an artificial intelligent monitoring system;
Fig. 3 is a schematic diagram of a bionic heart pulsatile pump and a bionic pulsatile pump base structure of an artificial intelligent monitoring system during extracorporeal circulation.
In the figure: 1. a bionic pulsating pump base; 2. a first placing groove; 3. a second placing groove; 4. pulsating sac-house; 5. pulsatile sac-chamber; 6. a blood input tube; 7. a flowmeter connection port; 8. a first electromagnetic piston extrusion column set; 9. a second electromagnetic piston extrusion column group; 10. a pulsating sac-atrioventricular pressure measuring connection port; 11. a pulsating sac-chamber output pressure measurement connection port; 12. a fixed bracket; 13. a chamber flap connecting tube; 14. monitoring a system host; 15. high-elasticity steel wire mesh enclosure; 16. a rubber pulsating bladder; 17. a biological membrane; 18. and a valve connecting pipe.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments.
Referring to fig. 1-3, a bionic heart pulsating pump and an artificial intelligent monitoring system during extracorporeal circulation comprises a bionic pulsating pump base 1, wherein a bionic heart pulsating pump main body, a first electromagnetic piston extrusion column group 8 and a second electromagnetic piston extrusion column group 9 are fixed on the bionic pulsating pump base 1, and the bionic heart pulsating pump main body consists of a blood input pipe 6, a pulsating sac-room 4, a room valve connecting pipe 18, a pulsating sac-room 5 and a room valve connecting pipe 13;
The blood input end 6, the pulsation sac-room 4, the room valve connecting pipe 18, the pulsation sac-room 5 and the room valve connecting pipe 13 are sequentially communicated, a flowmeter connecting port 7 is arranged at the rear side of the blood input end 6, and two pulsation sac-room pressure measuring connectors 10 are arranged on the room valve connecting pipe 18;
the first electromagnetic piston extrusion column group 8 is arranged in the position of the bionic pulsating pump base 1 positioned in the room valve connecting pipe 18, and the second electromagnetic piston extrusion column group 9 is arranged in the position of the bionic pulsating pump base 1 positioned in the room valve connecting pipe 13;
The pulsating sac-room 4 and the pulsating sac-room 5 comprise a strong elastic steel wire cover 15, a rubber pulsating sac 16 and a biological film 17 which are arranged from outside to inside, the shape of the pulsating sac after being expanded is in a spindle shape design, the functions of a room (A) room (V) and a heart valve of a human heart are simulated in a bionic mode, the pulsating blood flow can be generated, the physiological condition of the heart is similar to or approximate to that of normal heart work, and the perfusion of viscera and microcirculation is facilitated; the material adopts and has good biocompatibility material to make, this pulsation energy source is realized through the autonomous pulsation of extracorporeal circulation organization notes flow and pulsation perfusion bag, pulsation bag wall divides inlayer, middle level and skin, the inlayer is the biomembrane, can protect blood, the middle level is for having good elasticity and high compliance rubber layer, the skin is many strong elasticity wire mesh covers, the shrink of supplementary rubber pulsation bag, well outer layer structure's elasticity and compliance are the pulsation energy, produce surplus hemodynamic energy, room inter-bag junction and room bag export simulation mitral valve and aortic valve mouth, the temperature is invariable: the non-mechanical work, the electromagnetic work and the like do not generate heat, and the cooling treatment is not needed;
The initial driving kinetic energy can better fill the pulsation sac A as a left atrium of a human body by means of the flow generated by the extracorporeal circulation machine; the pulsation driving force mainly sources the compliance elasticity generated after the rubber and the steel wire of the pulsation sac are expanded, the back room valve is opened, the pulsation driving force is supplied to the pulsation sac V, after the pulsation sac V is filled to a certain volume and pressure, the room valve is opened again, the pulsation pouring once is completed, and the room valve and the opening and closing of the room valve are set and controlled by a control system;
the blood input tube 6 is connected with the arterial end of the pipeline of the extracorporeal circulation machine, and the blood output tube 13 is connected with the aortic cannula end;
the opening and closing of the atrioventricular valve are realized by pressing the opening pipeline through the electromagnetic piston column I8 and the electromagnetic piston column II 9, and the atrioventricular valve are alternately performed.
The bionic pulsating pump base 1 is sequentially provided with a first placing groove 2 and a second placing groove 3, a pulsating bag-room 4 is arranged in the first placing groove 2, and a pulsating bag-room 5 is arranged in the second placing groove 3.
The blood input tube 6 and the blood output tube 13 are arranged on the bionic pulsating pump base 1 through a fixed bracket.
The invention provides an artificial intelligent monitoring system of a bionic heart pulsating pump during extracorporeal circulation, which comprises an information acquisition component and a monitoring system host 14, wherein the information acquisition component comprises a flowmeter 7, two pulsating sac-atrioventricular pressure sensors 10 and an output pressure sensor 11.
The pulsating sac-room pressure measuring sensors 10 are arranged on the connecting pipes, the two pulsating sac-room pressure measuring sensors 10 are positioned on two sides of the electromagnetic piston post I8, the output pressure measuring sensor 11 is arranged on the blood output pipe 13 behind the valve, and the output pressure measuring sensor 11 is positioned at the rear end of the electromagnetic piston post II 9.
The information output ends of the external flowmeter, the two pulsation sac-room pressure measuring sensors and the pulsation sac-room pressure measuring sensors are respectively connected with the signal input end of the monitoring system host 14 through signal wires, and the signal output end of the monitoring system host 14 is connected with the first electromagnetic piston extrusion column group 8 and the second electromagnetic piston extrusion column group 9 through signal wires.
The operation flow is as follows:
1. The extracorporeal circulation artery end is connected with the blood input end 6 of the pulsation sac;
2. the exhaust in the pulsation sac is fully completed, the blood output pipe 13 of the pulsation sac is connected with the extracorporeal circulation vein reflux end to form a closed loop, test operation and check state, and the monitoring system host 14 is started to complete the simulation operation and check state;
3. after the aortic intubation is completed, the aortic intubation is connected with a pulsating sac blood output tube 13 to wait for formal extracorporeal circulation;
4. the device is discarded after the extracorporeal circulation is completed.
The foregoing is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art, who is within the scope of the present invention, should make equivalent substitutions or modifications according to the technical scheme of the present invention and the inventive concept thereof, and should be covered by the scope of the present invention.
Claims (6)
1. The bionic heart pulsating pump during the extracorporeal circulation comprises a bionic pulsating pump base (1), and is characterized in that a bionic heart pulsating pump main body, a first electromagnetic piston extrusion column group (8) and a second electromagnetic piston extrusion column group (9) are fixed on the bionic pulsating pump base (1), and the bionic heart pulsating pump main body consists of a blood input pipe (6), a pulsating sac-room (4), a room valve connecting pipe (18), a pulsating sac-room (5) and a room valve connecting pipe (13);
The blood input end (6), the pulsation sac-room (4), the room valve connecting pipe (18), the pulsation sac-room (5) and the room valve connecting pipe (13) are sequentially communicated, a flowmeter connecting port (7) is arranged at the rear side of the blood input end (6), two pulsation sac-room pressure measuring connectors (10) are arranged on the room valve connecting pipe (18), and a pulsation sac-room pressure measuring connector (11) is arranged on the room valve connecting pipe (13);
the first electromagnetic piston extrusion column group (8) is arranged in the position of the bionic pulsating pump base (1) located in the room valve connecting pipe (18), and the second electromagnetic piston extrusion column group (9) is arranged in the position of the bionic pulsating pump base (1) located in the room valve connecting pipe (13);
The pulsating bag-room (4) and the pulsating bag-room (5) comprise a strong elastic steel wire mesh cover (15), a rubber pulsating bag (16) and a biological film (17) which are arranged from outside to inside;
The blood input end (6) is connected with the arterial end of the extracorporeal circulation machine, and the ventricular valve connecting pipe (13) is connected with the aortic inserting end.
2. The bionic heart pulsating pump according to claim 1, wherein the bionic pulsating pump base (1) is provided with a first placing groove (2) and a second placing groove (3) in sequence, the pulsating sac-room (4) is arranged in the first placing groove (2), and the pulsating sac-room (5) is arranged in the second placing groove (3).
3. A biomimetic heart pulsatile pump during extracorporeal circulation according to claim 1, wherein the blood input (6) and the ventricular valve connecting tube (13) are mounted on the biomimetic pulsatile pump base (1) by means of a fixed bracket (12).
4. An artificial intelligence monitoring system of a biomimetic heart pulsatile pump during extracorporeal circulation according to claim 1, characterized in that the artificial intelligence monitoring system comprises an information acquisition assembly and a monitoring system host (14), the information acquisition assembly comprising a flow meter, two pulsatile capsule-atrial pressure sensors and a pulsatile capsule-ventricular pressure sensor.
5. The artificial intelligent monitoring system of the bionic heart pulsatile pump during extracorporeal circulation according to claim 4, wherein two pulsatile sac-atrioventricular pressure sensors are respectively connected to two pulsatile sac-atrioventricular pressure measuring connectors (10), the pulsatile sac-atrioventricular output pressure measuring sensors are connected to the pulsatile sac-atrioventricular output pressure measuring connectors (11), and a flowmeter is connected to the flowmeter connector (7).
6. The artificial intelligence monitoring system of the bionic heart pulsating pump during extracorporeal circulation according to claim 4, wherein the information output ends of the flowmeter, the two pulsating sac-atrioventricular pressure sensors and the pulsating sac-atrioventricular output pressure sensor are respectively connected with the signal input end of a monitoring system host (14) through signal wires, and the signal output end of the monitoring system host (14) is connected with the first electromagnetic piston extrusion column group (8) and the second electromagnetic piston extrusion column group (9) through signal wires.
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