CN118081128A - Laser drilling machine for mass-production osmotic pump tablets - Google Patents

Laser drilling machine for mass-production osmotic pump tablets Download PDF

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Publication number
CN118081128A
CN118081128A CN202410484099.0A CN202410484099A CN118081128A CN 118081128 A CN118081128 A CN 118081128A CN 202410484099 A CN202410484099 A CN 202410484099A CN 118081128 A CN118081128 A CN 118081128A
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CN
China
Prior art keywords
carrier
conveying
tablets
filling
hopper
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CN202410484099.0A
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Chinese (zh)
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CN118081128B (en
Inventor
周敏锋
顾继萍
高舒琦
袁秋杰
李明
于胜
孙珊
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Ruhlamat Automation Technologies Suzhou Co Ltd
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Ruhlamat Automation Technologies Suzhou Co Ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B23MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23KSOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
    • B23K26/00Working by laser beam, e.g. welding, cutting or boring
    • B23K26/36Removing material
    • B23K26/38Removing material by boring or cutting
    • B23K26/382Removing material by boring or cutting by boring
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B23MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23KSOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
    • B23K26/00Working by laser beam, e.g. welding, cutting or boring
    • B23K26/70Auxiliary operations or equipment
    • B23K26/702Auxiliary equipment

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Plasma & Fusion (AREA)
  • Mechanical Engineering (AREA)
  • Basic Packing Technique (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

The invention provides a mass production type osmotic pump tablet laser drilling machine which comprises a conveying mechanism, a filling mechanism, a recognition mechanism, a punching mechanism, a detection mechanism and a rejection mechanism, wherein the filling mechanism, the recognition mechanism, the punching mechanism, the detection mechanism and the rejection mechanism are sequentially arranged along the conveying direction, the conveying mechanism is used for conveying carriers to circulate among stations, the feeding mechanism above the filling mechanism is used for storing materials and feeding the materials to the filling mechanism, the filling mechanism is used for filling tablets into a trough of the carriers, the recognition mechanism is used for recognizing the front side and the back side of the tablets and the position of the tablets, the punching mechanism comprises an upper laser and a lower laser, one-sided or double-sided of the tablets can be punched according to information fed back by the recognition mechanism, the detection mechanism is used for detecting punching quality, defective tablets are rejected to a defective bin through the rejection mechanism according to detection results fed back by the detection mechanism, and qualified products fall into a finished bin through the conveying mechanism. The invention has simple structure, realizes the automatic production flow of feeding, filling, punching, detecting and discharging, and can realize high-speed, continuous, stable and batch production.

Description

Laser drilling machine for mass-production osmotic pump tablets
Technical Field
The invention relates to the technical field of pharmaceutical equipment, in particular to a laser drilling machine for mass production type osmotic pump tablets.
Background
Osmotic pump tablets are slow release tablet formulations having a semipermeable membrane on the surface thereof, which typically require the formation of release micropores in the semipermeable membrane. When the preparation is taken, water in the liquid can pass through the semipermeable membrane to enter the inner core of the preparation, the propellant in the inner core of the preparation begins to expand to generate pump side effect-pressure after absorbing the water, meanwhile, the preparation begins to dissolve, and the pressure increase forces the dissolved medicine to be slowly released and spread into a human body through the released micropores on the semipermeable membrane, so that the aim of stably controlling the release of the medicine is fulfilled, and the released micropores on the semipermeable membrane are vital to the release quality of the osmotic pump preparation.
The traditional punching mode is to use mechanical drilling, the machining precision and efficiency are lower, the tablets are easy to damage, and large-batch machining cannot be realized. Carbon dioxide lasers are used in many medical, materials processing, industrial manufacturing and other fields, especially in packaging code spraying and medical cosmetic applications. By utilizing the characteristics of the carbon dioxide laser, the coating layer of the controlled release preparation can be perforated, so that the processing efficiency, the processing precision and the stability are very high, and the consistency of medicine processing is ensured.
The existing laser-beam puncher usually completes tablet discharging, sorting and feeding through a vibration drug feeder, a vibration disc, a rotary disc and the like, then is conveyed to the laser-beam puncher through a conveying mechanism to punch holes, has single functions, and is lack of an online punching quality detection device and a defective product removing device. In addition, the existing laser puncher has the following defects: in the actual production process, the vibration drug feeder and the vibration disc are easy to abrade tablets, so that the stability of the release rate of the tablets is influenced, and meanwhile, the laser puncher is enabled to generate micro motion, so that the laser punching efficiency and accuracy are influenced; in addition, the turntable is adopted for sorting and feeding, so that the clamping is easy, the failure rate is high, only one tablet can enter a trough of the turntable at a time, the efficiency is low, and high-speed batch production cannot be realized; in addition, this structure can only realize unilateral punching, need dispose turning device upset tablet or tablet reflux unit screening incoming material in addition and just can realize that the tablet is two side to punch, lead to equipment overall structure complicacy, equipment cost increases, and influences the loading speed.
Disclosure of Invention
The invention aims to provide a mass-production osmotic pump tablet laser drilling machine, which overcomes the defects in the prior art.
In order to solve the technical problems, the technical scheme of the invention is as follows: the utility model provides a mass production osmotic pump tablet laser-beam drilling machine, includes conveying mechanism and along the filling mechanism, recognition mechanism, punching mechanism, detection mechanism, the rejection mechanism that conveying direction set gradually, conveying mechanism locates on the mainboard, is equipped with a plurality of carriers of loading tablet that set up along annular transport profile on it, and conveying mechanism is used for carrying the carrier circulation between each station, the filling mechanism top is equipped with feeding mechanism, feeding mechanism includes the hopper for the storage and according to the packing demand automatic feeding to filling mechanism, filling mechanism is used for filling the silo of carrier with the tablet in, recognition mechanism is used for discernment tablet positive and negative and position, including the recognition camera, the recognition camera is installed on the mainboard to just set up above the carrier; the punching mechanism comprises an upper laser arranged above the carrier and a lower laser arranged below the carrier, one side or both sides of the tablet can be punched according to the identification information fed back by the identification mechanism, the detection mechanism is used for detecting punching quality, the rejecting mechanism rejects unqualified tablets to a defective bin according to the detection result fed back by the detection mechanism, and the qualified products automatically fall into a finished bin through the conveying mechanism.
Further, the conveying mechanism is a chain plate type annular conveying chain, the annular conveying chain is obliquely arranged upwards along the conveying direction and comprises a linear conveying section obliquely arranged and arc sections arranged at two ends of the linear conveying section, and the filling mechanism, the identification mechanism, the punching mechanism, the detection mechanism and the rejecting mechanism are all arranged along the upper linear conveying section, so that the gravity direction of tablets in the carrier is opposite to the conveying traction direction; the carrier comprises carrier seats and carrier plates, the carrier seats are connected with chain links on the annular conveying chain in a one-to-one correspondence manner, a plurality of material grooves which are arranged in an array manner and used for filling tablets are arranged on the carrier plates, the carrier plates are connected with the carrier seats in an inserting manner, and one end of each material groove extends to the outer side of the annular conveying chain; and a mounting plate matched with the outer shape is arranged on the outer side of the annular conveying chain.
Further, the mass production type osmotic pump tablet laser drilling machine, wherein the feeding mechanism comprises a valve plate and a discharging pipe, the feeding hopper is formed by assembling an upper hopper body, a middle hopper body and a lower hopper body, the lower end of the middle hopper body is provided with a motor-driven valve plate, the hopper body above the valve plate is a tablet storage area, and the bottom of the feeding hopper is provided with the discharging pipe which is obliquely arranged towards the filling mechanism. And a material shortage sensor is arranged in the feeding port, and when the material is in shortage, the material shortage sensor sends a signal to the control system to prompt the feeding.
Further, the mass production type osmotic pump tablet laser drilling machine is characterized in that the filling mechanism is arranged on the conveying mechanism and comprises a filling hopper, a baffle plate group and a first brush, wherein the filling hopper is U-shaped, the opening direction of the filling hopper is a discharge hole arranged along the conveying direction, the discharge hole of the filling hopper is provided with the first brush, and the first brush is used for sweeping tablets stacked on the carrier into the filling hopper and smoothing the tablets on the carrier to enable the tablets to be placed in the trough; the baffle group is arranged below the filling hopper and comprises a plurality of transparent baffles, and the baffles cover the side edges of the filling hopper except the discharge hole. Preferably, the filler hopper discharge gate still is equipped with the striker plate, the striker plate sets up along the slope of a brush lateral surface filler hopper inside, and in order to guarantee that the tablet portion that gets into the filler hopper jumps out the filler hopper, the striker plate can dismantle with the filler hopper and be connected, the filler hopper discharge gate is equipped with the connecting rod of fixing on the filler hopper, it is equipped with a plurality of clamp splice to press from both sides on the connecting rod, the clamp splice is fixed on the striker plate to rotatable with the connecting rod is connected. In addition, a material level sensor is arranged in the filling hopper and is electrically connected with a motor for driving the valve plate.
Further, the mass production type osmotic pump tablet laser drilling machine, the filling mechanism further comprises a second hairbrush and a pressing roller which are sequentially arranged along the conveying direction, the second hairbrush is used for secondarily smoothing tablets, the pressing roller is used for secondarily smoothing tablets to push the standing tablets into the trough, the first hairbrush and the second hairbrush are arranged on the baffle group and are rotationally connected with the baffle group through driving mechanisms, the second hairbrush and the pressing roller are both located at the downstream of the hairbrush, and a static eliminator is further arranged between the second hairbrush and the pressing roller.
Further, in the mass production type osmotic pump tablet laser puncher, the upper lasers and the lower lasers are arranged in a vertically staggered mode, and the upper lasers and the lower lasers can punch tablets in a row of feed grooves perpendicular to the conveying direction on the carrier at each time.
Further, the detection mechanism comprises an upper detection camera and a lower detection camera, wherein the upper detection camera is arranged on the main board and is vertically arranged above a carrier positioned on the upper side of the conveying mechanism and used for detecting the punching quality of an upper laser, and the lower detection camera is arranged in the annular part of the conveying mechanism and is positioned right below the upper detection camera and used for detecting the punching quality of a lower laser; the lower detection camera is connected with the conveying mechanism through an electric cylinder, and the electric cylinder drives the lower detection camera to move along the direction perpendicular to the carrier so as to adjust the focal length of the lower detection camera.
Further, the removing mechanism of the mass production type osmotic pump tablet laser drilling machine comprises a first blowing component and a material channel box, wherein the first blowing component is arranged below the carrier and comprises a blowing seat and a plurality of independently controlled blowing needles arranged on the blowing seat, and a blowing port of each blowing needle is arranged in one-to-one correspondence with a material channel on the carrier; the material channel box is arranged above the carrier, a plurality of material channels corresponding to the blowing needle are arranged on the material channel box, one end of each material channel is provided with an inlet which is covered over one material groove, the other end of each material channel is communicated with the defective bin, and the material channel inlets, the material grooves and the blowing needle blowing openings which are correspondingly arranged are arranged on the same straight line from top to bottom and are coaxially arranged.
Further, the finished product bin comprises a feed hopper, wherein the feed hopper is arranged on the outer side of an arc-shaped section of the annular conveying chain, one side of the feed hopper, which is close to the annular conveying chain, is provided with an arc-shaped feed inlet which is coated on the outer part of the arc-shaped section and is matched with the shape of the arc-shaped section, and the feed inlet extends from the middle part of the arc-shaped section to a linear conveying section at the lower side; and a second blowing component arranged towards the feeding hole is further arranged in the conveying mechanism, and the second blowing component assists blanking of the tablets.
Further, the mass production type osmotic pump tablet laser drilling machine further comprises a rejection rechecking camera arranged on the conveying mechanism, wherein the rejection rechecking camera is arranged below the carrier and used for detecting whether the rejection mechanism rejects defective products or not.
Further, the mass production type osmotic pump tablet laser drilling machine further comprises a die changing mechanism, wherein the die changing mechanism comprises an upper pressing component and a lower pushing component, the upper pressing component is arranged above the carrier and comprises an upper pressing cylinder, an upper pressing seat and an upper pressing rod, the upper pressing cylinder is fixed on the main board through a cylinder mounting seat, the upper pressing seat is connected with the output end of the upper pressing cylinder, at least one upper pressing rod is arranged below the upper pressing seat, and the upper pressing rod is positioned above a mounting part of the carrier and the carrier seat in an inserting manner; the lower top assembly is arranged below the carrier and comprises a lower top cylinder and a lower top seat, the lower top cylinder is fixed on the conveying mechanism through a cylinder mounting seat, the lower top seat is connected with the output end of the lower top cylinder, at least one lower top rod I is arranged on one side, close to the mounting part of the carrier, of the top surface of the lower top seat, and a lower top rod II is arranged on the other side; and the lower ejector rod I can penetrate through the through hole in the carrier seat to be matched with the bottom surface of the carrier plate mounting part to lower one end of the carrier plate, and the lower ejector rod II is matched with the bottom surface of one end of the carrier plate provided with the trough to lower the other end of the carrier plate.
The invention also provides a working method of the mass production type osmotic pump tablet laser drilling machine, which comprises the following steps:
S1, feeding, namely conveying tablets into a feeding hopper, storing the tablets in the feeding hopper, and feeding the tablets into a filling hopper according to information fed back by a filling hopper level sensor;
S2, filling, namely starting a conveying mechanism, and filling tablets into a trough of a carrier under the action of the conveying mechanism and the filling mechanism;
S3, recognizing the state of the tablet, when the carrier filled with the tablet moves to the position below the recognition mechanism, photographing by the recognition camera, converting and recognizing the state of the tablet, and sending the state information of the tablet to the punching mechanism and the detection mechanism;
S4, punching, namely when the carrier filled with the tablets moves to a punching station, punching corresponding tablets in the carrier by the upper laser and the lower laser according to the tablet state information fed back by the identification mechanism, wherein the tablet state is abnormal, and the punching operation is not performed;
S5, quality detection, wherein when the perforated carrier moves to a detection station, the upper detection camera and the lower detection camera take pictures of the perforation state of the tablet to be processed according to tablet state information fed back by the identification mechanism, detect whether the tablet perforation quality meets the requirement or not, and send detection results to the rejection mechanism;
s6, reject and blanking, wherein when the carrier moves to the reject station, the reject mechanism blanks unqualified products to an reject bin according to the detection result fed back by the detection mechanism;
S7, removing the rechecking, when the carrier moves below the removing rechecking camera, photographing by the removing rechecking camera, detecting by an algorithm, detecting whether the products on the current carrier are qualified products, if so, immediately stopping the machine, and if so, entering the next step;
S8, discharging finished products, wherein when the carrier for loading the finished products moves to the feeding hopper through the conveying mechanism, tablets on the carrier fall into the finished product bin through the feeding hopper under the assistance of dead weight and the second blowing component.
Compared with the prior art, the invention has the beneficial effects that: according to the invention, the single side or the double sides of the product can be punched through the matching of the identification mechanism, the punching mechanism and the detection mechanism, and tablets do not need to be turned over or screened through the tablet reflux device, so that the structure is simple, and the operation is convenient; the feeding mechanism adopts the feeding hopper for feeding, vibration feeding is not needed, vibration to equipment can be reduced, abrasion to tablets is reduced, and the stability and punching accuracy of the equipment are improved; the filling and arranging of a plurality of tablets can be completed at one time by combining the filling mechanism with the obliquely arranged conveying mechanism, the filling rate and the filling precision of the tablets can be ensured, and the punching efficiency and the punching precision are greatly improved. The laser drilling machine realizes the automatic production flow of feeding, filling, punching, detecting and discharging, can realize high-speed, continuous, stable and batch production, can be compatible with various osmotic pump tablets with different types, and is convenient to change the shape.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are required to be used in the embodiments or the description of the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present invention, and other drawings may be obtained according to the drawings without inventive effort to those skilled in the art.
FIG. 1 is a schematic diagram of a mass-produced osmotic pump tablet laser drilling machine according to the present invention;
FIG. 2 is a schematic view of the internal structure of a mass-produced osmotic pump tablet laser drilling machine according to the present invention;
FIG. 3 is a front view of FIG. 2;
FIG. 4 is a schematic diagram of a packing mechanism and a delivery mechanism of a mass-produced osmotic pump tablet laser drilling machine according to the present invention;
FIG. 5 is a schematic view of a partial structure of a reject mechanism of a mass-produced osmotic pump tablet laser-beam drilling machine according to the present invention;
FIG. 6 is a schematic structural diagram of a die change mechanism of a mass-produced osmotic pump tablet laser drilling machine according to the present invention;
In the figure: 1. a conveying mechanism; 11. a carrier; 111. a carrier seat; 112. a carrier plate; 12. an endless conveyor chain; 121. a linear conveying section; 122. an arc section; 13. a mounting plate;
2. A feeding mechanism; 21. feeding a hopper; 22. a discharge pipe;
3. A filler mechanism; 31. a filling hopper; 32. a baffle group; 33. a first hairbrush; 34. a second hairbrush; 35. a press roller; 36. a static eliminator; 37. a striker plate; 371. a connecting rod; 372. clamping blocks; 38. a dust hood;
4. An identification mechanism;
5. a punching mechanism; 51. a laser is arranged; 52. a lower laser;
6. A detection mechanism; 61. a top detection camera; 62. a lower detection camera;
7. A rejecting mechanism; 71. a defective bin; 72. a blowing component I; 721. a blowing seat; 722. a blowing needle; 73. a material channel box; 731. a material channel;
81. a main board; 82. an outer frame; 83. a control cabinet;
91. a feed hopper; 911. a feed inlet; 92. a second blowing component;
10. Removing the recheck camera;
15. A die changing mechanism; 151. an upper pressing assembly; 1511. an upper pressure cylinder; 1512. an upper pressing seat; 1513. a pressing rod is arranged; 152. a lower roof assembly; 1521. a lower jacking cylinder; 1522. a lower top base; 1523. a lower ejector rod I; 1524. and a lower ejector rod II.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
As shown in fig. 1-6, a laser drilling machine for mass production type osmotic pump tablets comprises a conveying mechanism 1, and a filling mechanism 3, a recognition mechanism 4, a drilling mechanism 5, a detection mechanism 6 and a rejecting mechanism 7 which are sequentially arranged along the conveying direction, wherein the conveying mechanism 1 is arranged on a main board 81, a plurality of carriers 11 for loading tablets are arranged on the conveying mechanism along an annular conveying contour, the conveying mechanism 1 is used for conveying the carriers 11 to circulate among stations, a feeding mechanism 2 is arranged above the filling mechanism 3, the feeding mechanism 2 comprises a feeding hopper 21 and is used for storing materials and automatically feeding the filling mechanism 3 according to filling requirements, the filling mechanism 3 is used for filling the tablets into a trough of the carriers 11, the recognition mechanism 4 is used for recognizing the front and the back of the tablets and comprises a recognition camera, and the recognition camera is arranged on the main board 81 and is arranged right above the carriers 11; the punching mechanism 5 comprises an upper laser 51 arranged above the carrier 11 and a lower laser 52 arranged below the carrier 11, and can punch holes on one side or both sides of the tablets according to the identification information fed back by the identification mechanism 4, the detection mechanism 6 is used for detecting punching quality, the reject mechanism 7 rejects unqualified tablets to the defective bin 71 according to the detection result fed back by the detection mechanism 6, and the qualified products are conveyed by the conveying mechanism 1 and automatically fall into a finished product bin (not shown in the figure), namely, automatic blanking of the unqualified products and the qualified tablets is realized according to the detection result.
As shown in fig. 1, an outer frame 82 including the above functional mechanisms is disposed on the outer side of the main board 81, so as to ensure the cleanliness class of the medical device, a control cabinet 83 on the rear side of the main board 81 is disposed on one side of the outer frame 82, and a control system for controlling the functional mechanisms is disposed in the control cabinet 83, and the control system further includes auxiliary functional systems, such as alarm signal control, disk status monitoring, image storage module, file management, and the like.
In the above structure, as shown in fig. 1-3, the upper laser 51 and the lower laser 52 are disposed up and down in a staggered manner, and the upper laser 51 and the lower laser 52 can punch tablets in a row of the material grooves perpendicular to the conveying direction on the carrier 11 each time, and can punch a plurality of tablets at a time simultaneously. In addition, the back side of the main board 81 is also provided with a smoke removing component and a heat radiating component which are connected with the laser.
As shown in fig. 2-3, the mass production type osmotic pump tablet laser drilling machine of the invention further comprises a rejection rechecking camera 10 arranged on the conveying mechanism 1, wherein the rejection rechecking camera 10 is arranged below the carrier 11 and is used for detecting whether the rejection mechanism 7 rejects defective products. If not, stopping the processing, ensuring that the qualification rate of the product reaches 99.9%, and ensuring the quality of the tablets.
According to the invention, the single side or two sides of the product can be punched through the matching of the identification mechanism 4, the punching mechanism 5 and the detection mechanism 6, and tablets do not need to be turned over or screened by a tablet reflux device, so that the structure is simpler; in addition, the feeding mechanism 2 adopts the feeding hopper 21 for feeding, vibration feeding is not needed, vibration to equipment can be reduced, and the stability and punching accuracy of the equipment are improved. The laser drilling machine realizes the automatic production flow of feeding, filling, punching, detecting and discharging, can realize high-speed, continuous, stable and batch production, and can be compatible with various osmotic pump tablets with different types by changing carriers, setting system parameters and the like.
Example 2
Based on the structure of embodiment 1, as shown in fig. 2-4, the conveying mechanism 1 is a chain plate type annular conveying chain 12, the annular conveying chain 12 is obliquely arranged upwards along the conveying direction, the conveying mechanism comprises a linear conveying section 121 obliquely arranged and arc sections 122 arranged at two ends of the linear conveying section 121, and the filling mechanism 3, the identifying mechanism 4, the punching mechanism 5, the detecting mechanism 6 and the rejecting mechanism 7 are all arranged along the upper linear conveying section 122, so that the gravity direction of tablets in the carrier 11 is opposite to the conveying traction direction; through this setting, can let the automatic downward movement of stacked tablet fall into fill hopper 31 lower extreme, improve the filling rate of tablet on the carrier, and because be equipped with the clearance between tablet and the silo, after filling the tablet, the clearance that tablet and the horizontal carrier silo that sets up is located which side of silo is uncertain, can influence the punching accuracy, and conveyor 1's slope sets up, lets carrier 11 slope setting, can let tablet and silo downside butt, lets the biggest clearance of all tablets and silo be in the upside to guarantee the uniformity of punching position, improve the punching accuracy.
In the above structure, as shown in fig. 4, the carrier 11 includes a carrier seat 111 and a carrier plate 112, the carrier seat 111 is connected with links on the annular conveying chain 12 in a one-to-one correspondence manner, the carrier plate 112 is provided with a plurality of grooves for filling tablets, the filling of the tablets can be completed once through the cooperation of the carrier plate 112 and the annular conveying chain 12, the efficiency of filling and arranging materials is greatly improved, the carrier plate 112 is inserted into the carrier seat 111, and one end of the groove extends to the outer side of the annular conveying chain 12, so that the cooperation of each functional mechanism and the carrier can be facilitated; the outside of the annular conveying chain 12 is provided with a mounting plate 13 which is matched with the outside of the annular conveying chain, and the mounting plate 13 is used for mounting mechanisms which are respectively arranged inside the conveying mechanism 1.
As shown in fig. 1-3, the feeding mechanism 1 further includes a valve plate and a discharge pipe 22, the feeding hopper 21 is formed by assembling upper, middle and lower three-section hopper bodies, the feeding hopper is in a split structure, and can be conveniently disassembled and cleaned and maintained, the lower end of the middle hopper body is provided with a motor-driven valve plate, the hopper body above the valve plate is a tablet storage area, and the bottom of the feeding hopper 21 is provided with the discharge pipe 22 obliquely arranged towards the filling mechanism 3. The feeding hopper 21 is also internally provided with a material shortage sensor, and when the material is in shortage, the material shortage sensor sends a signal to the control system to prompt the feeding. The feeding hopper 21 adopts valve plate discharging, does not need sorting, has simple structure and convenient operation, does not adopt vibration feeding, can furthest reduce the abrasion to tablets, can reduce the vibration to equipment, and improves the stability and punching accuracy of the equipment.
As shown in fig. 2-4, the filling mechanism 3 is arranged on the conveying mechanism 1 and comprises a filling hopper 31, a baffle plate group 32 and a first brush, wherein the filling hopper 31 is arranged in a U shape, the opening direction of the filling hopper is a discharge hole arranged along the conveying direction, the discharge hole of the filling hopper 31 is provided with the first brush, and the first brush is used for sweeping tablets stacked on a carrier into the filling hopper and flattening the tablets on the carrier to enable the tablets to be placed in a trough; the baffle group 32 is arranged below the filling hopper 31 and comprises a plurality of transparent baffles, the baffles cover the side edges of the filling hopper 31 except the discharge hole, the baffle group 32 can be convenient for manually observing the condition in the filling hopper 31, and can also prevent tablets from leaking; as shown in fig. 4, the discharge port of the filling hopper 31 is further provided with a baffle 37, the baffle 37 is inclined towards the inside of the filling hopper 31 along the outer side of the first hairbrush 33, the baffle 37 is detachably connected with the filling hopper 31, the discharge port of the filling hopper 31 is provided with a connecting rod 371 fixed on the filling hopper 31, a plurality of clamping blocks 372 are clamped on the connecting rod 371, the clamping blocks 372 are fixed on the baffle 37 and are rotatably connected with the connecting rod 371, and the angle of the baffle 37 can be adjusted by adjusting the angle of the clamping blocks 372, so that tablets are prevented from jumping out of the filling hopper 31. In addition, a level sensor is arranged in the filling hopper 31, the level sensor is electrically connected with a motor for driving the valve plate, the tablet amount in the filling hopper 31 is controlled by the level sensor, and the conveying speed of the conveying mechanism is controlled, so that the tablet filling rate is highest. A dust hood 38 is arranged below the filling hopper 31 and is positioned below the carrier 11, and an upper end opening of the dust hood 38 covers a bottom opening of the filling hopper 31 and is used for sucking dust, tablet scraps and the like.
In addition, as shown in fig. 4, the filling mechanism 3 further includes a second brush 34 and a pressing roller 35 sequentially arranged along the conveying direction, the second brush 34 is used for secondarily smoothing tablets, the pressing roller 35 is used for secondarily smoothing tablets, the standing tablets are pushed into the trough, the pressing roller 35 is rotationally connected with the conveying mechanism 1 through a supporting rod, and the tablets are placed in the trough of the carrier in a horizontal state, so that the side surface to be punched is opposite to the upper laser and the lower laser; the first brush 33 and the second brush 34 are arranged on the baffle group 32 and are rotationally connected with the baffle group 32 through driving mechanisms (not shown in the figure), the driving mechanisms are belt transmission structures driven by servo motors, the second brush 34 and the press roller 35 are both positioned at the downstream of the first brush 33, and a static eliminator 36 is further arranged between the second brush 34 and the press roller 35 to eliminate static electricity of the second brush and the press roller, so that the effect of smoothing is prevented from being influenced by adhesion. During filling, a part of tablets are taken away by the carrier 11 through the lower part of the filling hopper 31, the first hairbrush 33 sweeps the tablets stacked on the carrier 112 into the filling hopper 31 when the tablets are discharged out of the discharge port, the other tablets are smoothed in the trough of the carrier 112 once, and then are smoothed in the trough of the carrier through the second hairbrush 34 and the pressing roller 35 twice and thrice, the tablets are basically filled into the trough of the carrier in the correct posture, the filling rate is high, the filling position is accurate, and filling and arranging of a plurality of tablets can be completed each time of filling, so that the punching efficiency is improved.
As shown in fig. 2-3, the detecting mechanism 6 includes an upper detecting camera 61 and a lower detecting camera 62, the upper detecting camera 61 is mounted on the main board 81 and is vertically arranged above the carrier 11 located at the upper side of the conveying mechanism 2 for detecting the punching quality of the upper laser 51, and the lower detecting camera 62 is mounted in the annular interior of the conveying mechanism 2 and is located under the upper detecting camera 61 for detecting the punching quality of the lower laser 52; the lower detection camera 62 is connected with the conveying mechanism 1 through an electric cylinder, and the electric cylinder drives the lower detection camera 62 to move along the direction vertical to the carrier 11 so as to adjust the focal length of the lower detection camera 62, and the moving distance is small. The punching quality comprises punching quantity, position, aperture and the like, and because the punching quality detection precision is higher, the lower detection camera 62 needs to be finely adjusted, in order to adapt to tablets with different thicknesses in different shapes, the distance between the tablet and the upper detection camera 61 is ensured by the design change of the carrier, and the thickness change of the lower surface of the corresponding tablet is adjusted by small movement of the lower detection camera 61 driven by the electric cylinder, so that the detection accuracy of the punching quality is ensured.
As shown in fig. 2,3 and 5, the removing mechanism 7 includes a first blowing component 72 and a material channel box 73, the first blowing component 72 is disposed below the carrier 11, and includes a blowing seat 721 and a plurality of independently controlled blowing needles 722 disposed on the blowing seat 721, and the blowing ports of each blowing needle 722 are disposed in one-to-one correspondence with the material channels on the carrier 11; the material channel box 73 is arranged above the carrier 11, a plurality of material channels 731 which are correspondingly arranged with the air blowing needles 722 are arranged on the material channel box, one end of each material channel 731 is an inlet which is covered over one trough, the other end of each material channel 731 is communicated with the inferior goods bin 71, a small gap is reserved between the bottom of each material channel 731 and the carrier plate 112, the carrier 11 can be ensured to pass through the gap smoothly, and the inlets of the material channels 731, the troughs and the air blowing openings of the air blowing needles 722 which are correspondingly arranged are arranged on the same straight line from top to bottom and are coaxially arranged. Namely, the air blowing needles, the material channels are arranged in one-to-one correspondence, the air blowing needles 722 at the positions of unqualified products are guaranteed to blow through the accurate control of the point positions of the control system, the air blowing needles 722 at the positions of the qualified products are not blown, and the inlets of the material channels 731 are covered over one material channel, so that when a plurality of products are removed at one time, the adjacent qualified requirements are not removed when the air blowing is removed.
As shown in fig. 2-3, the finished product bin comprises a feed hopper 91, the feed hopper 91 is arranged at the outer side of an arc-shaped section 122 of the annular conveying chain 12, an arc-shaped feed inlet 911 which is coated outside the arc-shaped section 122 and is matched with the shape of the arc-shaped section 122 is arranged at one side of the annular conveying chain 12, the feed inlet 911 extends from the middle part of the arc-shaped section 122 to a straight line conveying section 121 at the lower side, when the carrier 11 moves to the position of the feed inlet 911, the carrier 11 is converted from a vertical setting state to a downward setting state, and tablets fall into the feed hopper 91 freely under the action of dead weight and then fall into the finished product bin through a connecting pipe; in order to ensure that finished tablets on the carrier fall into the feeding hopper, a second blowing component 92 arranged towards the feeding hole 91 is further arranged inside the conveying mechanism 1, a plurality of blowing needles are arranged on the second blowing component 92, and the blanking of the tablet is assisted, so that the tablet clamping can be avoided.
As shown in fig. 2, 3 and 6, the mass production type osmotic pump tablet laser drilling machine of the invention further comprises a die changing mechanism 15, wherein the die changing mechanism 15 comprises an upper pressing component 151 and a lower top component 152, the upper pressing component is used for die loading and arranged above the carrier 11 and comprises an upper pressing cylinder 1511, an upper pressing seat 1512 and an upper pressing rod 1513, the upper pressing cylinder 1511 is fixed on the main board 81 through a cylinder mounting seat, the upper pressing seat 1512 is connected with the output end of the upper pressing cylinder 1511, at least one upper pressing rod 1513 is arranged below the upper pressing seat 1512, and the upper pressing rod 1513 is positioned above a mounting part of the carrier 112 and the carrier seat 111 in an inserting manner; the lower top assembly 152 is used for removing a mold, is arranged below the carrier 11 and is positioned under the upper pressing assembly 151, and comprises a lower top cylinder 1521 and a lower top seat 1522, wherein the lower top cylinder 1521 is fixed on the conveying mechanism 1 through a cylinder mounting seat, the lower top seat 1522 is connected with the output end of the lower top cylinder 1521, at least one lower top rod 1523 is arranged on one side, close to the mounting part of the carrier plate 112, of the top surface of the lower top seat 1522, and a lower top rod 1524 is arranged on the other side; driven by the lower jacking cylinder 1521, the first lower jacking rod 1523 can penetrate through a through hole in the carrier seat 111 to be matched with the bottom surface of the mounting part of the carrier plate 112 to jack one end of the carrier plate 112, the second lower jacking rod 1524 is matched with the bottom surface of one end of the carrier plate 112 provided with a trough to jack the other end of the carrier plate 112, and the setting of the first jacking rod and the second jacking rod can ensure that the upper jacking and the demolding are stable. When the carrier is required to be replaced due to cleaning maintenance or replacement of the tablet batch, the conveying mechanism 1 returns to zero, the carrier 11 on the conveying mechanism is driven to move to the initial position of die replacement, the manual control starting button controls the lower top assembly 152 to detach the carrier 112, then the carrier 112 is manually or mechanically removed, and a new carrier is roughly installed; starting the button again, controlling the upper pressing assembly 151, and installing the new carrier plate 112 in place; and then the steps are repeated until all the carriers 11 on the conveying mechanism 1 are replaced.
In addition, the identification mechanism 4, the punching mechanism 5, the detection mechanism 6 and the rejection and rechecking mechanism 10 in the mass production type osmotic pump tablet laser puncher are respectively provided with a quick-detachable shell, a partition plate arranged at intervals is arranged on the outer side of the mounting plate 13 of the conveying mechanism 1, and the mechanism arranged in the conveying mechanism 1 is isolated from the conveying mechanism 1, so that the requirements of medical grade D cleanliness and medical equipment GMP are met.
The invention also provides a working method of the mass production type osmotic pump tablet laser drilling machine, which comprises the following steps:
S1, feeding, namely conveying tablets into a feeding hopper 21, storing the tablets in the feeding hopper 21, and feeding the tablets into a filling hopper 31 according to information fed back by a material level sensor of the filling hopper 31;
S2, filling, namely starting a conveying mechanism 1, and filling tablets into a trough of a carrier 11 under the action of the conveying mechanism 1 and a filling mechanism 2, wherein the filling rate of the carrier reaches 99%;
S3, recognizing the tablet state, wherein when the carrier 11 filled with the tablets moves to the position below the recognition mechanism 4 (recognition station), the recognition camera photographs and performs conversion recognition on the tablet state, the tablet state comprises the front and back positions, whether tablets exist in the material groove, whether the tablets stand up or not and the like, and the tablet state information is sent to the punching mechanism 5 and the detection mechanism 6;
S4, punching, namely when the carrier 11 filled with the tablets moves to a punching station, the upper laser 51 and the lower laser 52 punch corresponding tablets in the carrier 11 according to the tablet state information fed back by the identification mechanism 4, wherein the tablet state is abnormal, if no tablet or the tablet stands up, the punching operation is not performed;
S5, quality detection, wherein when the perforated carrier 11 moves to a detection station, the upper detection camera 61 and the lower detection camera 62 take pictures of the perforation state of the tablets according to tablet state information fed back by the identification mechanism 4, whether the perforation quality of the tablets meets requirements or not is detected, the perforation quality comprises the perforation quantity, the position, the aperture and the like of the tablets, and a detection result is sent to the rejection mechanism 7;
S6, reject and blanking, wherein when the carrier 11 moves to a reject station, the reject mechanism 7 is used for blanking unqualified products to the reject bin 71 according to the detection result fed back by the detection mechanism 6; the unqualified condition comprises that the hole is not punched, the punching position deviates from the center of the tablet, the tablet stands up, and the like;
S7, removing the recheck, when the carrier 11 moves to the position below the removing recheck camera 10, photographing by the removing recheck camera 10, performing algorithm detection, detecting whether the products on the current carrier 11 are all qualified products, if so, immediately stopping the machine, and if so, entering the next step;
s8, blanking the finished product, and when the carrier 11 for loading the finished product moves to the feed hopper 91 through the conveying mechanism 1, the tablets on the carrier fall into the finished product bin through the feed hopper 91 under the assistance of the dead weight and the blowing component II 92.
The whole implementation process adopts intelligent automatic operation, is convenient to operate, and the conveying mechanism 1 does not need to stop when punching and removing, can continuously run, can punch single side or double sides of a product through the matching of the identifying mechanism 4, the punching mechanism 5 and the detecting mechanism 6, does not need to overturn tablets or screen tablets through a tablet reflux device, realizes the automatic production flow of feeding, filling, punching, detecting and discharging, and can realize high-speed, continuous, stable and batch production.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present disclosure describes embodiments, not every embodiment is provided with a separate embodiment, and that this description is provided for clarity only, and that the disclosure is not limited to the embodiments described in detail below, and that the embodiments described in the examples may be combined as appropriate to form other embodiments that will be apparent to those skilled in the art.

Claims (10)

1. A mass production type osmotic pump tablet laser drilling machine is characterized in that: including conveying mechanism and along the feeding mechanism, identifying mechanism, punching mechanism, detection mechanism, the rejection mechanism that the direction of delivery set gradually, conveying mechanism locates on the mainboard, is equipped with a plurality of carriers of loading tablet that set up along annular transport profile on it, and conveying mechanism is used for carrying the carrier circulation between each station, the feeding mechanism top is equipped with feeding mechanism, feeding mechanism includes the hopper for the storage and according to the packing demand automatic feeding to the feeding mechanism, the feeding mechanism is used for filling the silo of carrier with the tablet in, identifying mechanism is used for discernment tablet positive and negative and position, punching mechanism is including locating the last laser instrument of carrier top and locating the lower laser instrument of carrier below, can punch to tablet single face or two-sided according to the identification information of identifying mechanism feedback, detecting mechanism is used for detecting punching quality, reject the mechanism and reject the defective chip to the defective bin according to the testing result of detecting mechanism feedback, the defective goods then is carried automatically through conveying mechanism and falls into the finished product storehouse.
2. The mass produced osmotic pump tablet laser drilling machine according to claim 1, wherein: the conveying mechanism is a chain plate type annular conveying chain, the annular conveying chain is obliquely arranged upwards along the conveying direction and comprises a linear conveying section obliquely arranged and arc sections arranged at two ends of the linear conveying section, and the filling mechanism, the identifying mechanism, the punching mechanism, the detecting mechanism and the rejecting mechanism are all arranged along the upper linear conveying section, so that the gravity direction of tablets in the carrier is opposite to the conveying traction direction; the carrier comprises carrier seats and carrier plates, the carrier seats are connected with chain links on the annular conveying chain in a one-to-one correspondence manner, a plurality of material grooves which are arranged in an array manner and used for filling tablets are arranged on the carrier plates, the carrier plates are connected with the carrier seats in an inserting manner, and one end of each material groove extends to the outer side of the annular conveying chain; and a mounting plate matched with the outer shape is arranged on the outer side of the annular conveying chain.
3. The mass produced osmotic pump tablet laser drilling machine according to claim 1, wherein: the feeding mechanism comprises a valve plate and a discharging pipe, the feeding hopper is formed by assembling upper, middle and lower three-section hopper bodies, the lower end of the middle hopper body is provided with a motor-driven valve plate, the hopper body above the valve plate is a tablet storage area, and the bottom of the feeding hopper is provided with the discharging pipe which is obliquely arranged towards the filling mechanism.
4. A mass produced osmotic pump tablet laser drilling machine according to claim 3, wherein: the filling mechanism is arranged on the conveying mechanism and comprises a filling hopper, a baffle plate group and a first brush, wherein the filling hopper is U-shaped, the opening direction of the filling hopper is a discharge hole arranged along the conveying direction, the first brush is arranged at the discharge hole of the filling hopper and is used for sweeping tablets stacked on the carrier into the filling hopper and smoothing the tablets on the carrier to enable the tablets to be placed in the trough; the baffle plate group is arranged below the filling hopper and comprises a plurality of transparent baffle plates, and the baffle plates cover the side edges of the filling hopper except the discharge hole; the filling mechanism further comprises a second hairbrush and a pressing roller which are sequentially arranged along the conveying direction, the second hairbrush is used for secondarily smoothing tablets, and the pressing roller is used for thirdly smoothing the tablets to push the standing tablets into the trough; the first hairbrush and the second hairbrush are arranged on the baffle group and are rotationally connected with the baffle group through driving of the driving mechanism, the second hairbrush and the press roller are both positioned at the downstream of the hairbrush, and a static eliminator is further arranged between the second hairbrush and the press roller.
5. The mass produced osmotic pump tablet laser drilling machine according to claim 1, wherein: the upper lasers and the lower lasers are arranged in a vertically staggered mode, and the upper lasers and the lower lasers can punch tablets in a row of feed grooves perpendicular to the conveying direction on the carrier at each time.
6. The mass produced osmotic pump tablet laser drilling machine according to claim 1 or 5, wherein: the detection mechanism comprises an upper detection camera and a lower detection camera, the upper detection camera is arranged on the main board and is vertically arranged above a carrier positioned on the upper side of the conveying mechanism and used for detecting the punching quality of an upper laser, and the lower detection camera is arranged in the annular part of the conveying mechanism and is positioned right below the upper detection camera and used for detecting the punching quality of a lower laser; the lower detection camera is connected with the conveying mechanism through an electric cylinder, and the electric cylinder drives the lower detection camera to move along the direction perpendicular to the carrier so as to adjust the focal length of the lower detection camera.
7. The mass produced osmotic pump tablet laser drilling machine according to claim 1, wherein: the removing mechanism comprises a blowing assembly I and a material channel box, wherein the blowing assembly I is arranged below the carrier and comprises a blowing seat and a plurality of independently controlled blowing needles arranged on the blowing seat, and a blowing port of each blowing needle is arranged in one-to-one correspondence with a material groove on the carrier; the material channel box is arranged above the carrier, a plurality of material channels corresponding to the blowing needle are arranged on the material channel box, one end of each material channel is provided with an inlet which is covered over one material groove, the other end of each material channel is communicated with the defective bin, and the material channel inlets, the material grooves and the blowing needle blowing openings which are correspondingly arranged are arranged on the same straight line from top to bottom and are coaxially arranged.
8. The mass produced osmotic pump tablet laser drilling machine according to claim 1, wherein: the finished product bin comprises a feed hopper, the feed hopper is arranged on the outer side of an arc-shaped section of the annular conveying chain, one side of the feed hopper, which is close to the annular conveying chain, is provided with an arc-shaped feed inlet which is coated on the outer part of the arc-shaped section and is matched with the shape of the arc-shaped section, and the feed inlet extends from the middle part of the arc-shaped section to a linear conveying section on the lower side; and a second blowing component arranged towards the feeding hole is further arranged in the conveying mechanism, and the second blowing component assists blanking of the tablets.
9. The mass produced osmotic pump tablet laser drilling machine according to claim 1, wherein: the device also comprises a rejection rechecking camera arranged on the conveying mechanism, wherein the rejection rechecking camera is arranged below the carrier and used for detecting whether the rejection mechanism rejects defective products or not.
10. The mass produced osmotic pump tablet laser drilling machine according to claim 1, wherein: the die changing mechanism comprises an upper pressing assembly and a lower pushing assembly, the upper pressing assembly is arranged above the carrier and comprises an upper pressing cylinder, an upper pressing seat and an upper pressing rod, the upper pressing cylinder is fixed on the main board through a cylinder mounting seat, the upper pressing seat is connected with the output end of the upper pressing cylinder, at least one upper pressing rod is arranged below the upper pressing seat, and the upper pressing rod is positioned above a mounting part of the carrier and the carrier seat in an inserting manner; the lower top assembly is arranged below the carrier and comprises a lower top cylinder and a lower top seat, the lower top cylinder is fixed on the conveying mechanism through a cylinder mounting seat, the lower top seat is connected with the output end of the lower top cylinder, at least one lower top rod I is arranged on one side, close to the mounting part of the carrier, of the top surface of the lower top seat, and a lower top rod II is arranged on the other side; and the lower ejector rod I can penetrate through the through hole in the carrier seat to be matched with the bottom surface of the carrier plate mounting part to lower one end of the carrier plate, and the lower ejector rod II is matched with the bottom surface of one end of the carrier plate provided with the trough to lower the other end of the carrier plate.
CN202410484099.0A 2024-04-22 2024-04-22 Laser drilling machine for mass-production osmotic pump tablets Active CN118081128B (en)

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CN201192758Y (en) * 2008-03-10 2009-02-11 韩梅林 Laser boring system apparatus of controlled-release pharmaceutical tablet
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CN208583658U (en) * 2018-08-03 2019-03-08 安徽古井贡酒股份有限公司 A kind of metal box-lid automatic code-printing and stamp substandard products automatic reject mechanism
CN212169364U (en) * 2020-04-24 2020-12-18 上海现代药物制剂工程研究中心有限公司 Osmotic pump controlled release tablet laser-beam drilling machine with multi-track rough tablet conveying turntable assembly
CN114799546A (en) * 2022-04-01 2022-07-29 武汉华工激光工程有限责任公司 Full-automatic laser drilling method and equipment

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040094050A1 (en) * 2002-11-13 2004-05-20 Ackley Machine Corporation Laser unit, inspection unit, method for inspecting and accepting/removing specified pellet-shaped articles from a conveyer mechanism, and pharmaceutical article
CN201192758Y (en) * 2008-03-10 2009-02-11 韩梅林 Laser boring system apparatus of controlled-release pharmaceutical tablet
CN201320294Y (en) * 2008-12-18 2009-10-07 韩梅玲 Laser boring device for controlled release tablets
CN202571610U (en) * 2012-04-06 2012-12-05 成都康弘药业集团股份有限公司 Laser tablet drilling machine with osmotic pump
CN102699539A (en) * 2012-06-14 2012-10-03 天津工业自动化仪表研究所有限公司 Full-function osmotic pump controlled-release tablet laser-beam drilling machine
CN208583658U (en) * 2018-08-03 2019-03-08 安徽古井贡酒股份有限公司 A kind of metal box-lid automatic code-printing and stamp substandard products automatic reject mechanism
CN212169364U (en) * 2020-04-24 2020-12-18 上海现代药物制剂工程研究中心有限公司 Osmotic pump controlled release tablet laser-beam drilling machine with multi-track rough tablet conveying turntable assembly
CN114799546A (en) * 2022-04-01 2022-07-29 武汉华工激光工程有限责任公司 Full-automatic laser drilling method and equipment

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