CN112452224A - Stirring device and centralized liquid supply system - Google Patents
Stirring device and centralized liquid supply system Download PDFInfo
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- CN112452224A CN112452224A CN202011052697.9A CN202011052697A CN112452224A CN 112452224 A CN112452224 A CN 112452224A CN 202011052697 A CN202011052697 A CN 202011052697A CN 112452224 A CN112452224 A CN 112452224A
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Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/82—Combinations of dissimilar mixers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/20—Jet mixers, i.e. mixers using high-speed fluid streams
- B01F25/23—Mixing by intersecting jets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/50—Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle
- B01F25/52—Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle with a rotary stirrer in the recirculation tube
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/10—Maintenance of mixers
- B01F35/145—Washing or cleaning mixers not provided for in other groups in this subclass; Inhibiting build-up of material on machine parts using other means
- B01F35/1452—Washing or cleaning mixers not provided for in other groups in this subclass; Inhibiting build-up of material on machine parts using other means using fluids
- B01F35/1453—Washing or cleaning mixers not provided for in other groups in this subclass; Inhibiting build-up of material on machine parts using other means using fluids by means of jets of fluid, e.g. air
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/181—Preventing generation of dust or dirt; Sieves; Filters
- B01F35/187—Preventing generation of dust or dirt; Sieves; Filters using filters in mixers, e.g. during venting
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/22—Control or regulation
- B01F35/221—Control or regulation of operational parameters, e.g. level of material in the mixer, temperature or pressure
- B01F35/2215—Temperature
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/7179—Feed mechanisms characterised by the means for feeding the components to the mixer using sprayers, nozzles or jets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/75—Discharge mechanisms
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/75—Discharge mechanisms
- B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
- B01F35/7547—Discharge mechanisms characterised by the means for discharging the components from the mixer using valves, gates, orifices or openings
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/80—Forming a predetermined ratio of the substances to be mixed
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- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
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Abstract
The utility model provides a stirring apparatus and concentrated liquid supply system, wherein, stirring apparatus includes: the bottom of the stirring barrel is provided with a liquid outlet; at least one ejector group arranged in the stirring barrel, wherein each ejector group comprises two ejectors with parallel and opposite ejection directions; and the inlet of the stirring pump is connected with the liquid outlet, and the outlet of the stirring pump is connected with the inlets of the two ejectors. The stirring device provided by the disclosure can shorten the time for preparing the dialysate.
Description
Technical Field
The invention relates to the technical field of hemodialysis, in particular to a stirring device and a centralized liquid supply system.
Background
Hemodialysis, as a renal replacement therapy mode for patients with acute and chronic renal failure, is to drain blood in a patient body into hollow fibers of a dialysis machine, perform substance exchange such as dispersion, ultrafiltration and adsorption on the blood and dialysate (electrolyte solution) outside the hollow fibers of the dialysis machine and having similar body concentration, remove metabolic waste and water in the patient body, maintain acid-base balance and homeostasis, and return purified blood to the patient body in the whole process.
The hemodialysis concentrated solution used by the dialysis machine is called dialysate for short. The dialysate comprises concentrate A and concentrate B, and is prepared from dialysate (including powder A and powder B) and pure water. Specifically, the concentrated solution A is a strongly acidic concentrated solution obtained by mixing powder A (including sodium chloride, potassium chloride, calcium chloride, magnesium chloride, glacial acetic acid, etc.) with pure water; the concentrated solution B is a saturated solution of sodium bicarbonate obtained by mixing powder B (sodium bicarbonate) with pure water.
Currently, two ways of barreled supply and centralized supply are mainly adopted to provide dialysate for a dialysis machine. The centralized supply mode can greatly reduce the purchase cost of the barreled dialysate and reduce the labor intensity of medical care personnel, so the barreled dialysate is widely applied. The dialysate (i.e., the a and B concentrates) is first prepared before being provided to the dialysis machine in a centralized supply.
In the related art, a blade type stirring device is usually used for stirring to accelerate the preparation of the dialysate. However, the time for preparing the dialysate by adopting the existing stirring device is still long, particularly, the dissolving speed of the B powder for preparing the B concentrated solution in pure water is very slow, the time for mixing the B powder and the pure water according to a certain proportion and completely dissolving the B powder is very long, the liquid preparation time is more than 70 minutes, and the demand of a dialysis machine in a centralized supply mode for preparing the dialysate is difficult to meet.
Disclosure of Invention
An object of the disclosed embodiment is to provide a stirring device and a centralized liquid supply system, which can shorten the time for preparing dialysate. The specific technical scheme is as follows:
in one aspect, an embodiment of the present disclosure provides a stirring device, including:
the bottom of the stirring barrel is provided with a liquid outlet;
at least one ejector group arranged in the stirring barrel, wherein each ejector group comprises two ejectors with parallel and opposite ejection directions; and the number of the first and second groups,
and the inlet of the stirring pump is connected with the liquid outlet, and the outlet of the stirring pump is connected with the inlets of the two ejectors.
In some embodiments, the stirring barrel comprises a cylindrical section and a conical section which are sequentially arranged from top to bottom, and the bottom of the cylindrical section is connected with the large end of the conical section;
the liquid outlet is arranged at the small end of the conical section.
In some embodiments, further comprising a circulation tube, a first branch tube and a second branch tube; the inlet of the circulating pipe is connected with the outlet of the stirring pump, and the outlet of the circulating pipe is connected with the inlet of the first branch pipe and the inlet of the second branch pipe;
one of the at least one injector group is located at a transition junction of the barrel section and the cone section;
the outlet of the first branch pipe is connected with the inlet of one ejector in one ejector group, and the outlet of the second branch pipe is connected with the inlet of the other ejector in one ejector group.
In some embodiments, further comprising a screen; the filter screen sets up in the toper section and be located the top of tip.
In some embodiments, a center tube;
the central pipe is positioned above the filter screen and communicated with the first branch pipe and the second branch pipe;
the bottom of the central tube is provided with a plurality of through holes corresponding to the filter screen.
In some embodiments, the through holes are kidney-shaped holes and are two in number;
the plane where the generatrix at the bottom of the central tube and the axis of the central tube are located is a plane B; the two waist-shaped holes are symmetrical about the plane B;
the two ends of the waist-shaped hole are respectively provided with an arc section, and the plane where the central axes of the two arc sections are located is an A plane; the included angle between the plane A and the plane B is less than or equal to 20 degrees.
In some embodiments, the two ejectors are venturi ejectors.
In some embodiments, the stirring barrel is provided with a plurality of flow restraining plates arranged along the circumferential direction of the barrel wall and extending along the vertical direction.
In some embodiments, the end side of the flow restraining plate away from the wall of the stirring barrel is in a tooth shape;
in two adjacent flow restraining plates, the gear teeth of one flow restraining plate and the gear teeth grooves of the other flow restraining plate are located at the same height.
In some embodiments, the circulation tube is provided with at least one of a resistance heater, a temperature sensor, and a conductivity probe.
On the other hand, the embodiment of the present disclosure further provides a centralized liquid supply system, which includes the stirring device of the first aspect.
In some embodiments, the centralized liquid supply system provided by the embodiments of the present disclosure further includes a filtering device for filtering the dialysate output by the stirring device;
the filtering device includes:
a filter assembly comprising a first fluid port and a second fluid port;
the working liquid inlet pipeline is connected with the first liquid port;
the ultrafiltration component comprises a third liquid port, a fourth liquid port and a fifth liquid port;
the first connecting pipeline is communicated with the second liquid port and the third liquid port;
the first three-way valve comprises a first valve port, a second valve port and a third valve port, the first valve port and the second valve port are arranged on the first connecting pipeline, and the first valve port is closer to the second liquid port;
the working solution pipeline is connected with the fourth solution port;
the back washing pump is arranged on the working solution making pipeline, and the liquid outlet side is closer to the fourth liquid port than the liquid inlet side;
the flushing liquid inlet pipeline is connected with the part of the first connecting pipeline, which is positioned between the second liquid port and the first valve port;
the positive flushing liquid discharge pipeline is connected with the part of the working solution pipeline, which is positioned between the fourth liquid port and the back flushing pump;
the back flushing drainage pipeline is connected with the fifth liquid port;
and the ultrafiltration return pipeline is connected to the back-washing liquid discharge pipeline.
In some embodiments, the centralized liquid supply system provided by the embodiments of the present disclosure further includes a post-stage liquid distribution conveying system connected to the working liquid pipeline;
the post-stage liquid distribution and conveying system comprises a liquid storage device and a plurality of concentrated liquid supply conveying units arranged on different floors, wherein the liquid storage device is arranged below the liquid supply conveying unit on the lowest floor in the plurality of concentrated liquid supply conveying units,
each centralized liquid supply conveying unit comprises:
the pressure relief device is arranged on the conveying pipeline, and the conveying pipeline is connected with the pressure relief device;
the first liquid level detection device and the second liquid level detection device are arranged on the outer wall of the pressure release device, the first liquid level detection device is closer to the top of the pressure release device than the second liquid level detection device, the first liquid level detection device is used for sending a first signal when detecting that the liquid level is not less than the first liquid level height, and the second liquid level detection device is used for sending a second signal when detecting that the liquid level is not less than the second liquid level height;
the controller is electrically connected with the booster pump, the first liquid level detection device and the second liquid level detection device; the controller controls the booster pump to reduce the liquid flow entering the conveying pipeline when receiving the first signal and the second signal, controls the booster pump to keep the liquid flow entering the conveying pipeline unchanged when receiving the second signal and not receiving the first signal, and controls the booster pump to increase the liquid flow entering the conveying pipeline when not receiving the first signal and the second signal.
In some embodiments, the centralized liquid supply system provided by the embodiments of the present disclosure further includes a liquid storage and supply device connected to the working liquid outlet pipeline of the filtering device;
the liquid storage and supply device comprises:
the liquid storage device comprises a liquid outlet and a circulating liquid inlet which are arranged at the bottom, and a liquid inlet and an air outlet which are arranged at the top;
one end of the liquid inlet pipeline is connected with a liquid inlet of the liquid storage device, and the other end of the liquid inlet pipeline is used for introducing liquid;
the exhaust device is connected with an exhaust port of the liquid storage device;
the circulating liquid inlet pipeline is connected with a circulating liquid inlet of the liquid storage device;
the positive pressure pump is arranged on the liquid outlet pipeline, and one end of the liquid outlet pipeline is connected with a liquid outlet of the liquid storage device;
the liquid return pipeline and the negative pressure pump are arranged on the liquid return pipeline, one end of the liquid return pipeline is connected with the circulating liquid inlet pipeline, and the connection position of the liquid return pipeline is far away from the circulating liquid inlet of the liquid storage device than the first valve;
the second valve comprises a seventh valve port and an eighth valve port, and the seventh valve port is connected with the other end of the circulating liquid inlet pipeline;
the liquid level control device comprises a back-stage pipeline and a first switch valve arranged on the back-stage pipeline, wherein one end of the back-stage pipeline is connected with the other end of the liquid outlet pipeline, and the other end of the back-stage pipeline is connected with the other end of the liquid return pipeline.
In the scheme that this disclosed embodiment provided, agitator bottom liquid outlet and agitator outer agitator pump's access connection set up the at least a set of sprayer of being connected with the agitator pump export in the agitator, and every group sprayer includes two sprayers that the direction of spraying is parallel and reverse. Pumping out the mixed solution of the dialysis powder (powder A or powder B) and the pure water in the stirring barrel through a stirring pump and spraying the mixed solution into the stirring barrel through at least one group of sprayers; in the process of mixed liquid circulating delivery, the sprayer continuously sprays the mixed liquid, the rotating torque generated by the sprayed mixed liquid pushes the mixed liquid in the stirring barrel to rotate, and the mixed liquid in the stirring barrel is stirred, so that the dialysis powder is quickly dissolved in pure water, and the time for preparing the dialysis liquid can be effectively shortened.
In addition, the mixed liquid is continuously sprayed by the sprayer in the stirring barrel to push the mixed liquid to rotate, so that the mixed liquid in the stirring barrel can be stirred in a non-contact manner; compare in the contact stirring that adopts the blade, blade direct contact mixed liquid in the contactless stirring mode of this disclosed embodiment has avoided the contact stirring mode in the stirring process to the condition of polluting the mixed liquid takes place.
Drawings
In order to more clearly illustrate the embodiments of the present disclosure or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other embodiments can be obtained by using the drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a stirring device provided in an embodiment of the present disclosure;
FIG. 2 is a top view of a stirring device provided by an embodiment of the present disclosure;
fig. 3 is a schematic structural diagram of a stirring barrel of a stirring device provided in an embodiment of the present disclosure;
FIG. 4 is a schematic structural diagram of a filtering device in a centralized liquid supply system according to an embodiment of the disclosure;
FIG. 5 is a schematic structural view of a centralized liquid supply system provided by an embodiment of the present disclosure;
FIG. 6 is a schematic diagram of the post-mix delivery system of FIG. 5;
FIG. 7 is a schematic view of another centralized liquid supply system provided by the disclosed embodiment;
FIG. 8 is a schematic structural diagram of the liquid storage and supply device in FIG. 7.
Detailed Description
The technical solutions in the embodiments of the present disclosure will be clearly and completely described below with reference to the drawings in the embodiments of the present disclosure, and it is obvious that the described embodiments are only a part of the embodiments of the present disclosure, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The embodiment of the disclosure provides a stirring device and a centralized liquid supply system, which can shorten the time for preparing dialysate, thereby effectively meeting the demand of a dialysis machine for preparing the dialysate in a centralized supply mode.
A stirring device provided in an embodiment of the present disclosure will be described below with reference to the accompanying drawings.
As shown in fig. 1 to 3, an embodiment of the present disclosure provides a stirring device, including:
the stirring barrel 100 is provided with a liquid outlet at the bottom of the stirring barrel 100;
at least one injector group arranged in the mixing tank 100, each injector group comprising two injectors 301, 302 with parallel and opposite injection directions; and the number of the first and second groups,
the inlet of the stirring pump 200 is connected with the liquid outlet, and the outlet of the stirring pump 200 is connected with the inlets of the two ejectors 301 and 302.
Before stirring, dialysis powder (powder A or powder B) and pure water need to be added into a stirring barrel according to a certain proportion, and the liquid volume of the mixed liquid of the pure water and the dialysis powder in the stirring barrel can be accurately controlled through a pressure transmitter and a liquid level sensor which are arranged in the stirring barrel.
And after the liquid preparation is finished, delivering the prepared dialysate to a back-stage pipeline for use by a dialysis machine. As shown in fig. 1, in the stirring device provided in the embodiment of the present disclosure, a stirring pump 200 is connected to inlets of the ejectors 301 and 302 and an inlet of a stirring liquid outlet line 215 through an electric ball valve 214. Thus, after the liquid preparation is completed, the prepared dialysate can be conveyed to the dialysis machine for use through the stirring liquid outlet line 215 by controlling the electric ball valve 214. Of course, instead of the mixing pump 200, other pumps may be used to pump the prepared dialysate and deliver it to the subsequent lines.
In the scheme that this disclosed embodiment provided, agitator bottom liquid outlet and agitator outer agitator pump's access connection set up the at least a set of sprayer of being connected with the agitator pump export in the agitator, and every group sprayer includes two sprayers that the direction of spraying is parallel and reverse. Pumping out the mixed solution of the dialysis powder (powder A or powder B) and the pure water in the stirring barrel through a stirring pump and spraying the mixed solution into the stirring barrel through at least one group of sprayers; in the process of mixed liquid circulating delivery, the sprayer continuously sprays the mixed liquid, the rotating torque generated by the sprayed mixed liquid pushes the mixed liquid in the stirring barrel to rotate, and the mixed liquid in the stirring barrel is stirred, so that the dialysis powder is quickly dissolved in pure water, and the time for preparing the dialysis liquid can be effectively shortened.
In addition, the mixed liquid is continuously sprayed by the sprayer in the stirring barrel to push the mixed liquid to rotate, so that the mixed liquid in the stirring barrel can be stirred in a non-contact manner; compare in the contact stirring that adopts the blade, blade direct contact mixed liquid in the contactless stirring mode of this disclosed embodiment has avoided the contact stirring mode in the stirring process to the condition of polluting the mixed liquid takes place.
In some embodiments, the stirring barrel 100 includes a cylindrical section and a conical section sequentially arranged from top to bottom, and the bottom of the cylindrical section is connected with the large end of the conical section; the liquid outlet is arranged at the small end of the conical section.
In the embodiment of the disclosure, the stirring barrel is arranged to be of a structure with a cylindrical section at the upper part and a conical section at the lower part, and the small end of the conical section is provided with a liquid outlet, so that on one hand, pure water can be injected from the bottom of the stirring barrel, and dialysis powder deposited at the bottom of the stirring barrel is flushed along with water inlet, and on the other hand, in the stirring process, mixed liquid containing undissolved dialysis powder is uninterruptedly pumped out from the bottom of the stirring barrel, and then the mixed liquid is injected into the stirring barrel, so that the mixed liquid in the stirring barrel can flow; through the two effects, the dissolving speed of the dialysis powder can be increased, and the time for preparing the dialysate is further reduced.
In some embodiments, the stirring device may further comprise a circulation pipe 201, a first branch pipe 202, and a second branch pipe 203; an inlet of the circulation pipe 201 is connected with an outlet of the stirring pump 200, and an outlet of the circulation pipe 201 is connected with an inlet of the first branch pipe 202 and an inlet of the second branch pipe 203;
one of the at least one injector group is located at a transition junction of the barrel section and the cone section;
the outlet of the first branch pipe 202 is connected to the inlet of one injector 301 of one of the injector groups, and the outlet of the second branch pipe 203 is connected to the inlet of another injector 302 of one of the injector groups.
When the ejector set is only one set, the ejector set is arranged at the transition joint of the cylindrical section and the conical section and is connected with the stirring pump through the first branch pipe, the second branch pipe and the circulating pipe. When the ejector groups are in a plurality of groups, one ejector group is arranged at the transition joint of the cylindrical section and the conical section and is connected with the stirring pump through the first branch pipe, the second branch pipe and the circulating pipe; other sets of ejectors may be connected to the agitator pump in the same manner as the set of ejectors described above.
In the embodiment of the disclosure, the ejector of one ejector set is arranged at the transitional connection position, so that both the ejection torque and the ejection stroke can be taken into consideration, and a better stirring effect is achieved.
In some embodiments, the stirring device may further comprise a screen 101; the screen 101 is disposed within the conical section and above the small end.
In the embodiment of the disclosure, the filter screen is arranged above the small end of the conical section, so that large impurities and foreign matters can be filtered out, and the large impurities and the foreign matters are prevented from entering the stirring pump through the liquid outlet and damaging the stirring pump; and can prevent large impurities and foreign matters from blocking the conveying pipeline in the process of conveying the prepared dialysate to the subsequent pipeline.
In some embodiments, the stirring device may further comprise a center tube 102; the central pipe 102 is positioned above the filter screen 101 and is communicated with a first branch pipe 202 and a second branch pipe 203;
the bottom of the center tube 102 is provided with a plurality of through holes opposite to the filter screen 101.
In the stirring process, vortex is easily formed at the center of the stirring barrel, the solution at the center of the stirring barrel cannot flow sufficiently, and dialysis powder deposition, particularly B powder deposition, is easily formed at the center of the barrel bottom. In the embodiment of the disclosure, a central pipe for connecting two ejectors is arranged, and the bottom of the central pipe is provided with a through hole, so that a part of mixed liquid can be shunted from liquid flow supplied to the ejectors by a stirring pump; the part of mixed liquid is sprayed out through the through holes to sweep the deposited dialysis powder at the filter screen, and the deposited dialysis powder is swept again, so that the dissolving effect of the dialysis powder can be further improved.
In some embodiments, the through holes are kidney-shaped holes and are two in number; the plane where the generatrix at the bottom of the central tube 102 and the axis of the central tube 102 are located is a plane B; the two waist-shaped holes are symmetrical about a plane B;
the two ends of the waist-shaped hole are respectively provided with an arc section, and the plane where the central axes of the two arc sections are located is an A plane; the included angle between the A plane and the B plane is less than or equal to 20 degrees.
In the embodiment of the disclosure, two downward inclined waist-shaped holes are formed in the bottom of the central tube relative to the filter screen, so that dialysis powder, especially B powder, can be better deposited on the filter screen, and the dissolving effect of the dialysis powder is further improved.
In some embodiments, both ejectors 301, 302 are venturi ejectors.
Compared with a common ejector, such as a flat nozzle ejector, the venturi ejector adopted by the embodiment of the disclosure can accelerate the fluid speed by reducing the fluid flow from thick to thin by utilizing the venturi principle, so that the fluid forms a vacuum area at the rear side of the outlet of the venturi, and the vacuum area generates certain suction to generate adsorption and push the fluid to flow.
In some embodiments, the stirring barrel 100 is provided with a plurality of flow inhibiting plates 103 arranged along the circumferential direction of the barrel wall and extending in the vertical direction.
When the mixed liquid in the stirring barrel is less, the ejector is easy to splash when stirring the mixed liquid, and particularly when a large-torque Venturi ejector is adopted for stirring, the splashing condition is serious. The embodiment of the disclosure can effectively inhibit splashing by vertically arranging the plurality of flow inhibiting plates on the wall of the stirring barrel along the circumferential direction.
In some embodiments, the flow suppressing plate 103 is toothed at the end side away from the wall of the agitator 100; in two adjacent choke plates 103, the teeth of one choke plate 103 and the teeth grooves of the other choke plate 103 are located at the same height.
In the embodiment of the disclosure, the tooth spaces of the two adjacent flow restraining plates are located at the same height with the tooth spaces of the other flow restraining plate through the plurality of tooth-shaped flow restraining plates arranged along the circumference of the barrel wall. Namely, the gear teeth and the tooth grooves are arranged at intervals along the circumference at the same horizontal position. Here, the gear teeth refer to a convex portion on the choke plate 103, and the tooth-shaped choke plate is a choke plate provided with the gear teeth. Therefore, after the gear teeth of the former flow restraining plate realize flow restraining, the gear teeth can be released through the gear teeth of the latter flow restraining plate, so that the flow restraining is ensured, the flow restraining is not excessive, the uniformity and the stability of the stirring process can be effectively ensured, and the dissolving effect of the dialysis powder is further improved. When specifically setting up, can adopt a plurality of the same profile of tooth to restrain the class board, will follow a plurality of profile of tooth that the circumferencial direction of bucket wall was arranged and restrain class board at first height and second height alternate arrangement, first height and second height can differ a tooth width.
In some embodiments, the circulation tube 201 is provided with at least one of a resistive heater 211, a temperature sensor 212, and a conductivity probe 213.
The preparation of the B concentrated solution in the dialysate is greatly influenced by seasons, particularly, the B powder in a room with lower room temperature is extremely difficult to dissolve in winter, and the B powder is easy to deposit at the bottom of the stirring barrel, so that the normal use of the dialysate is influenced. This disclosed embodiment sets up resistance heater through at the circulating line, can heat the mixed liquid of flow through the pipeline, is favorable to fully dissolving of B powder, can further reduce the preparation B concentrate time.
In the disclosed embodiments, the temperature sensor may be electrically connected to the resistive heater. In the whole stirring process, the temperature sensor can detect and feed back temperature signals in real time, the heating power of the resistance heater can be adjusted in real time according to the temperature, the mixed liquid is ensured to be at the optimal dissolving temperature, and thus the dissolving effect of the dialysis powder is further improved.
In the embodiment of the disclosure, the dissolving state of the dialysis powder can be accurately obtained through the conductivity probe, and the prepared dialysate can be timely conveyed to a later-stage pipeline.
The stirring device provided by the embodiment of the disclosure can be used for preparing dialysate in hemodialysis, and can effectively shorten the preparation time of the dialysate (especially B concentrated solution); the method can also be applied to other fields, such as the field of drinks and the like, and effectively shortens the time for preparing similar solutions.
The embodiment of the disclosure also provides a centralized liquid supply system which comprises the stirring device in the embodiment of the disclosure.
In addition, the centralized liquid supply system provided by the embodiment of the present disclosure further includes a filtering device for filtering the dialysate output by the stirring device, as shown in fig. 4, the filtering device includes: a filter assembly 1 comprising a first port 1a and a second port 1 b; the working liquid inlet pipeline 2 is connected with the first liquid port 1 a; an ultrafiltration module 3 comprising a third port 3a, a fourth port 3b and a fifth port 3 c; a first connection line 4 for connecting the second port 1b and the third port 3 a; a first three-way valve 5 including a first port 5a, a second port 5b, and a third port 5c, wherein the first port 5a and the second port 5b are disposed on the first connection pipe 4, and the first port 5a is closer to the second liquid port 1 b; the working solution pipeline 6 is connected with the fourth solution port 3 b; the back washing pump 7 is arranged on the working solution making pipeline 6, and the liquid outlet side is closer to the fourth liquid port 3b than the liquid inlet side; a flushing liquid inlet pipe 8 connected to a portion of the first connecting pipe 4 between the second liquid port 1b and the first valve port 5 a; the positive flushing liquid discharge pipeline 9 is connected with the part of the working liquid outlet pipeline 6, which is positioned between the fourth liquid port 3b and the back flushing pump 7; a back flushing drainage pipeline 10 connected with the fifth liquid port 3 c; and an ultrafiltration return line 12 connected to the backwash drainage line 10.
When the filtering device is in a filtering working state, the working liquid inlet pipeline 2 is connected with the stirring liquid outlet pipeline 215 of the stirring system, and the working liquid outlet pipeline 6 can be directly connected with a rear-stage conveying pipeline (not shown in the figure) or can be simultaneously connected with the liquid storage barrel 30. The working solution inlet line 2 may be filled with an alkaline solution (for example, a solution of solution B, which is mainly composed of sodium bicarbonate or an aqueous solution of sodium bicarbonate and sodium chloride) or an acidic solution (for example, a solution of solution A, which is mainly composed of an aqueous solution of sodium chloride, potassium chloride, calcium chloride, magnesium chloride, acetic acid, etc.). After the liquid is sequentially filtered by bacteria and impurities through the filtering component 1 and the ultrafiltration component 3, the liquid B or the liquid A meeting the requirement flows out of the working liquid outlet pipeline 6 to be conveyed to a backward-stage conveying pipeline or stored in the liquid storage barrel 30.
The filter device further includes: and the second three-way valve 11 is arranged on the working fluid production pipeline 6 and is positioned between the fourth fluid port 3b and the backwashing pump 7, the second three-way valve 11 comprises a fourth valve port 11a, a fifth valve port 11b and a sixth valve port 11c, the fourth valve port 11a and the fifth valve port 11b are arranged on the working fluid production pipeline 6, the fourth valve port 11a is closer to the fourth fluid port 3b, the sixth valve port 11c is used for being communicated with the fluid storage barrel 30 through a pipeline 13 (the filtering device does not comprise the fluid storage barrel 30), and the forward-flushing drainage pipeline 9 is connected with the part of the working fluid production pipeline 6, which is positioned between the fifth valve port 11b and the backwashing pump 7. After the liquid preparation is sequentially filtered by bacteria and impurities through the filtering component 1 and the ultrafiltration component 3, the liquid B or liquid A meeting the requirement is conveyed from the working liquid outlet pipeline 6 to the rear-stage conveying pipeline or the liquid storage barrel 30.
In some embodiments, the filtration device further comprises: the first switch valve 14 is arranged on the working fluid pipeline 6 and is positioned between the fourth fluid port 3b and the fourth valve port 11 a; a second switch valve 15 arranged on the flushing liquid inlet pipeline 8 and a bypass switch valve 19 connected with the second switch valve 15 in parallel; a third on-off valve 16 arranged on the positive flushing drain line 9; a fourth switch valve 17 arranged on the back washing drainage pipeline 10, and the ultrafiltration return pipeline 12 is connected with the part of the back washing drainage pipeline 10 positioned between the fifth liquid opening 3c and the fourth switch valve 17; and a fifth on-off valve 18 disposed on the ultrafiltration return line 12.
Further, in some embodiments of the present disclosure, the filtration device may further comprise at least one of: the first pressure detection device 20 is arranged on the working liquid inlet pipeline 2, and the first sampling branch is connected with the working liquid inlet pipeline 2 and is provided with a sixth switch valve 21; a second pressure detection device 22 provided on the working fluid line 6; and a second sampling branch connected with the working liquid outlet pipe 6, wherein a seventh switch valve 23 is arranged on the second sampling branch.
The working modes of the filtering device comprise a filtering working mode, a positive flushing working mode, a first backwashing working mode and a second backwashing working mode.
In the filtering operation mode, the backwash pump 7 is closed, the first valve port 5a and the second valve port 5b of the first three-way valve 5 are opened, the third valve port 5c is closed, the fourth valve port 11a and the sixth valve port 11c of the second three-way valve 11 are opened, the fifth valve port 11b is closed, the first switch valve 14 and the fifth switch valve 18 are opened, the second switch valve 15, the bypass switch valve 19, the third switch valve 16 and the fourth switch valve 17 are closed, the prepared liquid to be filtered flows in from the working liquid inlet pipeline 2, the filtered liquid is stored in the liquid storage barrel 30, and the redundant filtered liquid flows back through the partial backwash discharge pipeline 10 and the ultrafiltration return pipeline 12 in sequence, for example, flows back to the pipeline upstream of the filtering device.
In the positive flushing operation mode, the back flushing pump 7 is closed, the first valve port 5a and the second valve port 5b of the first three-way valve 5 are opened, the third valve port 5c is closed, the fourth valve port 11a and the fifth valve port 11b of the second three-way valve 11 are opened, the sixth valve port 11c is closed, the first switch valve 14, the second switch valve 15 and the third switch valve 16 are opened, the bypass switch valve 19, the fourth switch valve 17 and the fifth switch valve 18 are closed, the flushing liquid flows in from the flushing liquid inlet pipeline 8, the ultrafiltration module 3 is flushed in the positive direction, and finally the flushing liquid is discharged from the positive flushing liquid discharge pipeline 9.
In the first backwashing operation mode, the backwashing pump 7 is turned off, the first valve port 5a and the third valve port 5c of the first three-way valve 5 are opened, the second valve port 5b is closed, the fourth valve port 11a, the fifth valve port 11b and the sixth valve port 11c of the second three-way valve 11 are closed, the second on-off valve 15 and the fourth on-off valve 17 are opened, the first on-off valve 14, the third on-off valve 16, the bypass on-off valve 19 and the fifth on-off valve 18 are closed, and a washing liquid flows in from the washing liquid inlet pipeline 8, performs backwashing on the ultrafiltration module 3, and is finally discharged from the backwashing liquid discharge pipeline 10.
In the second backwashing operation mode, the backwashing pump 7 is turned on, the first valve port 5a, the second valve port 5b and the third valve port 5c of the first three-way valve 5 are closed, the fourth valve port 11a and the fifth valve port 11b of the second three-way valve 11 are opened, the sixth valve port 11c of the second three-way valve 11 is closed, the first switch valve 14, the fourth switch valve 17 and the fifth switch valve 18 are opened, the second switch valve 15, the third switch valve 16 and the bypass switch valve 19 are closed, and the washing liquid flows in from the operation liquid outlet pipeline 6 to perform reverse washing on the ultrafiltration module 3, and then one path is discharged through the backwashing liquid discharge pipeline 10, and the other path flows back through the ultrafiltration return pipeline 12, for example, flows back to the stirring system.
In some embodiments, in the forward flush mode of operation and the first backwash mode of operation, the flush fluid comprises at least one of a base formulation (e.g., a formulation of solution B) and reverse osmosis water. In the second backwash operation mode, the flushing liquid comprises a thermally decomposed base solution (e.g., thermally decomposed solution B).
In some embodiments, in the centralized liquid supply system for hemodialysis, some of the latter-stage delivery pipelines are provided with heating devices, and in the second backwashing working mode, the liquid B is heated and decomposed to form a strong base and weak acid salt solution, and the pH value is about 11. Under the effect of back flush pump 7, strong base weak acid salt solution gets into ultrafiltration module 3's inside from work drain pipe 6 as heat antiseptic solution, when carrying out the backwash to ultrafiltration module 3, can destroy the cell structure of bacterium, virus etc. in ultrafiltration module 3 and the relevant pipeline to harmful substance such as kill bacterium, virus.
The filter device of the embodiment of the disclosure can realize multistage filtration through the built-in high-precision filtering component and the ultrafiltration component, and further effectively ensures a dialysis environment. The filtering device is used as an important link for ensuring each index of the dialysate to reach the standard, the filtering effect is superior to the standard, and the use is safe and reliable. The filter equipment of this disclosed embodiment, can come dirt and bacterium on the automatic clearance ultrafiltration module 3 filter wall through positive and negative washing, the combined heat disinfection of commodity circulation chemistry on its structural design for ultrafiltration module's availability factor promotes, and life is longer.
In addition, the centralized liquid supply system provided by the embodiment of the disclosure further includes a post-stage liquid distribution conveying system connected to the working liquid outlet pipe 6 of the filtering device, and the structure of the centralized liquid supply system is shown in fig. 5. Referring to fig. 6, the post-stage liquid distribution delivery system includes a liquid storage device 46 and a plurality of centralized liquid supply delivery units disposed at different floors. Dialysate from the filter enters the reservoir 46. The liquid storage device 46 is positioned below the liquid supply conveying unit at the lowest floor in the plurality of centralized liquid supply conveying units.
Each centralized liquid supply conveying unit comprises:
a conveying pipeline 43 respectively connected with a liquid storage device 46, and a booster pump 42 and a pressure release device 44 arranged on the conveying pipeline 43, wherein the booster pump 42 is closer to a liquid inlet of the conveying pipeline 43 than the pressure release device 44, and the maximum cross-sectional area of an inner cavity of the pressure release device 44 is larger than the cross-sectional area of the conveying pipeline 43;
the first liquid level detection device 451 and the second liquid level detection device 452 are arranged on the outer wall of the pressure release device 44, the first liquid level detection device 451 is closer to the top of the pressure release device 44 than the second liquid level detection device 452, the first liquid level detection device 451 is used for sending a first signal when detecting that the liquid level is not less than the first liquid level height, and the second liquid level detection device 452 is used for sending a second signal when detecting that the liquid level is not less than the second liquid level height; and
a controller electrically connected to the booster pump 42, the first liquid level detection device 451, and the second liquid level detection device 452; the controller controls the booster pump 42 to reduce the flow of liquid into the transfer line 43 when receiving the first signal and the second signal, controls the booster pump 42 to keep the flow of liquid into the transfer line 43 constant when receiving the second signal and not receiving the first signal, and controls the booster pump 42 to increase the flow of liquid into the transfer line 43 when not receiving the first signal and the second signal.
As shown in fig. 6, the liquid storage device 46 is connected to the centralized liquid supply conveying unit 411, the centralized liquid supply conveying unit 412 and the centralized liquid supply conveying unit 413 through pipelines, the number of floors of the centralized liquid supply conveying unit 411 is smaller than that of the centralized liquid supply conveying unit 412 and the centralized liquid supply conveying unit 413, and the number of floors of the liquid storage device 46 is smaller than that of the centralized liquid supply conveying unit 411. For example, the liquid storage device 46 may be disposed on the first floor, and the concentrated liquid supply transport unit 411, the concentrated liquid supply transport unit 412, and the concentrated liquid supply transport unit 413 may be disposed on the second floor, the third floor, and the fourth floor, respectively.
In the centralized liquid supply system for hemodialysis, the liquid to be conveyed is pressurized by the pressurizing pump 42 so as to be conveyed, the pressure relief device 44 can accumulate the liquid because the maximum cross-sectional area of the inner cavity of the pressure relief device 44 is larger than the cross-sectional area of the conveying pipeline 43, the pressure of the liquid is released after the liquid reaches the pressure relief device 44, and finally the liquid discharged from the liquid outlet of the conveying pipeline 43 is micro-pressure or non-pressure, so that the non-pressure liquid supply requirement of partial instruments in the hemodialysis process is met, and non-pressure, reliable and simultaneous liquid supply on different floors is realized.
The first level detection means 451 and the second level detection means 452 are provided primarily to monitor the level of the liquid in the pressure relief device 44, and thereby regulate the booster pump 42 to control the flow of liquid into the delivery line 43. When the liquid level in the pressure relief device 44 reaches the position of the first liquid level detection device 451, i.e., the first liquid level height, the first liquid level detection device 451 can detect the liquid level and send a first signal, and the second liquid level detection device 452 can detect the liquid level and send a second signal. The first liquid level detecting device 451 is disposed closer to the top of the pressure relief device 44, which indicates that there is more liquid in the pressure relief device 44, and in order to avoid the liquid level being higher and generating new pressure in the pressure relief device 44, the pressure pump 42 is controlled to reduce the flow rate of the liquid into the delivery pipe 43, so that the liquid level in the pressure relief device 44 gradually decreases. When the fluid level in the pressure relief device 44 is between the positions of the first fluid level detection device 451 and the second fluid level detection device 452, the first fluid level detection device 451 does not detect the fluid level, and the second fluid level detection device 452 may detect the fluid level and emit a second signal, i.e., a second fluid level. The liquid level height at this time can not only release the pressure of the liquid just entering the pressure release device 44, but also can not generate new pressure due to the liquid level height, therefore, when the controller receives the second signal and does not receive the first signal, the flow rate of the liquid entering the conveying pipeline 43 by the booster pump 42 is controlled to be unchanged, and the purpose of non-pressure and reliable liquid supply of the present disclosure can be achieved. When the liquid level in the pressure relief device 44 is below the position of the second liquid level detecting device 452, at this time, neither the first liquid level detecting device 451 nor the second liquid level detecting device 452 can detect the liquid level, which indicates that the liquid level in the pressure relief device 44 is too low, and the pressure of the liquid newly entering the pressure relief device 44 may not be released in time, so that it is necessary to control the pressurizing pump 42 to increase the flow rate of the liquid entering the conveying pipeline 43, so as to raise the liquid level in the pressure relief device 44.
Therefore, the centralized liquid supply system for hemodialysis provided by the disclosure can control the flow of the booster pump to realize cross-floor, non-pressure and reliable liquid supply when the controller receives the first signal and/or the second signal, and the centralized liquid supply conveying unit has a simple structure and strong controllability. In addition, the liquid in the centralized liquid supply conveying unit is always in a flowing state, so that bacteria are not easy to breed in pipelines and other devices, and the health of patients is facilitated.
As shown in fig. 6, in some embodiments of the present disclosure, the conveying pipeline 43 is finally connected to the dialysis machine 48 through a post-stage pipeline, and conveys the liquid in the centralized liquid supply system for hemodialysis to the dialysis machine 48. In some embodiments of the present disclosure, the pressure of the liquid discharged from the liquid outlet of the conveying line 43 by the centralized liquid supply system for hemodialysis is less than or equal to 0.1 kPa. Since the dialysis machine 48 needs to supply liquid under no pressure in the working state, otherwise, the dialysis machine cannot work normally, and the pressure of the liquid discharged from the liquid outlet of the conveying pipeline 43 can ensure the normal work of the dialysis machine 48 within the above range.
In addition, the centralized liquid supply system provided by the embodiment of the disclosure further comprises a liquid storage and supply device, a working liquid outlet pipeline of the filtering device is connected with a liquid inlet pipeline in the liquid storage and supply device, and the structure of the centralized liquid supply system is shown in fig. 7. As shown in fig. 8, in some embodiments of the present disclosure, a liquid storage and supply device includes:
the liquid storage device 311 comprises a liquid outlet 6a and a circulating liquid inlet 6b which are arranged at the bottom, and a liquid inlet 6c and an air outlet 6d which are arranged at the top; a liquid inlet pipeline 351, one end of which is connected with the liquid inlet 6c of the liquid storage device 311, and the other end of which is used for introducing liquid; an exhaust device 312 connected to the exhaust port 6d of the liquid storage device 311; a circulating liquid inlet pipeline 321 and a first valve 322 arranged on the circulating liquid inlet pipeline 321, wherein one end of the circulating liquid inlet pipeline 321 is connected with a circulating liquid inlet 6b of the liquid storage device 311; a liquid outlet pipeline 331 and a positive pressure pump 332 arranged on the liquid outlet pipeline 331, wherein one end of the liquid outlet pipeline 331 is connected with a liquid outlet 6a of the liquid storage device 311; a liquid return pipeline 341 and a negative pressure pump 342 disposed on the liquid return pipeline 341, wherein one end of the liquid return pipeline 341 is connected with the circulating liquid inlet pipeline 321, and the connection position is further away from the circulating liquid inlet 6b of the liquid storage device 311 than the first valve 322; a second valve 323 comprising a seventh valve port 7a and an eighth valve port 7b, wherein the seventh valve port 7a is connected with the other end of the circulating liquid inlet pipeline 321; a post-stage pipeline 361 and a first switch valve 362 arranged on the post-stage pipeline 361, one end of the post-stage pipeline 361 is connected with the other end of the liquid outlet pipeline 331, and the other end of the post-stage pipeline 361 is connected with the other end of the liquid return pipeline 341. The other end of the liquid inlet pipe 351 may be connected to the filter device 38, and the filter device 38 is not included in the liquid storage and supply device.
When the hemodialysis system does not work for maintenance, the liquid storage and supply device is in a circulation degassing mode, wherein the first valve 322 and the first switch valve 362 are opened, and the second valve 323 is closed. The liquid passing through the filtering device 38 enters the liquid storage device 311 through the liquid inlet pipeline 351, the positive pressure pump 332 in the liquid storage and supply device can push the liquid in the liquid storage device 311 to enter the liquid outlet pipeline 331 and then enter the rear-stage pipeline 361, then bubbles in the pipelines are broken under the action of the negative pressure pump 342, the liquid enters the liquid storage device 311 through the circulating liquid inlet pipeline 321, the gas is discharged through the gas discharge device 312, and the reciprocating circulation is repeated for multiple times, so that the bubbles in the pipelines and other equipment can be removed, and the normal operation of the hemodialysis system is guaranteed.
In some embodiments of the present disclosure, the liquid storage and supply device further comprises: the first heating device 333 is arranged on the liquid outlet pipeline 331 and is farther away from the liquid outlet a of the liquid storage device 311 than the positive pressure pump 332; the second heating device 343 is arranged on the liquid return pipeline 341 and is closer to the connection part of the liquid return pipeline 341 and the circulating liquid inlet pipeline 321 than the negative pressure pump 342; the drain line 324 has one end connected to the eighth port 7b of the second valve 323, and the other end serving as a drain port. The drain port of the drain line 324 may be connected to a waste liquid recovery device 325.
The liquid outlet pipe 331 and the liquid return pipe 341 are provided with heating devices for heating liquid, and the liquid storage and supply device can be subjected to heat sterilization, and the method comprises the following two stages:
in the first stage, the liquid storage and supply device is in the first setting time period of the cyclic heat sterilization mode, at this time, the first valve 322, the first switch valve 362, the first heating device 333 and the second heating device 343 are opened, and the seventh port 7a and the eighth port 7b of the second valve 323 are closed. The first heating device 333 and the second heating device 343 can heat the liquid in the pipeline, then sequentially pass through the liquid outlet pipeline 331, the post-stage pipeline 361 and the liquid return pipeline 341, and then enter the liquid storage device 311 through the circulating liquid inlet pipeline 321, so that the whole pipeline is circularly and thermally sterilized for many times, and microorganisms such as bacteria and the like bred in the pipeline are removed.
And in the second stage, after the first set time period, the liquid storage and supply device is in a second set time period of the cyclic heat sterilization mode, wherein the first switching valve 362, the seventh port 7a and the eighth port 7b of the second valve 323, the first heating device 333 and the second heating device 343 are opened, and the first valve 322 is closed. The liquid which completes the circulating heat sterilization is discharged into a waste liquid recovery device 325 through a liquid discharge pipeline 324, and the whole circulating heat sterilization process is completed.
In some embodiments of the present disclosure, the liquid in the liquid storage and supply device is a sodium bicarbonate aqueous solution, and the aqueous solution is alkaline, so that bacteria and viruses generated by the liquid storage and supply device during normal operation can be inactivated, the purpose of sterilization and virus removal is achieved, physical-chemical combined heat disinfection is formed, and the efficiency of heat disinfection is improved. The above setting time periods may be determined according to actual needs or experience.
In some embodiments of the present disclosure, the liquid storage and supply device further includes a circulation line 371 and a second switch valve 372 disposed on the circulation line 371, one end of the circulation line 371 is connected to the liquid outlet line 331 and the connection point is closer to the other end of the liquid outlet line 331 than the first heating device 333, and the other end of the circulation line 371 is connected to the liquid return line 341 and the connection point is closer to the other end of the liquid return line 341 than the negative pressure pump 342. Because the later-stage pipeline 361 has a long path, the temperature rise amplitude is slow in the liquid heating process, and heat is easy to lose. The circulation line 371 can shorten the flow path of the liquid during heating, thereby reducing heat loss and improving heating efficiency.
In some embodiments of the present disclosure, the liquid storage and supply device further includes a temperature detection device 313 disposed on a sidewall of the liquid storage device 311, and the temperature detection device 313 is configured to detect a temperature of the liquid in the liquid storage device 311. When the liquid is not heated to the target temperature, the liquid storage and supply device is in a circulation heating mode, the seventh valve port 7a and the eighth valve port 7b of the first switch valve 362 and the second valve 323 are closed, the first valve 322 and the second switch valve 372 are opened, the liquid enters the liquid return pipeline 341 from the circulation pipeline 371 and then enters the liquid storage device 311, and the liquid is circulated and heated in a short pipeline path. When the liquid is heated to the target temperature, the first valve 322 and the first switch valve 362 are opened, the second switch valve 372 and the seventh valve port 7a and the eighth valve port 7b of the second valve 323 are closed, so that the liquid directly enters the subsequent pipeline 361, and the whole pipeline is subjected to heat sterilization. Therefore, the heating and the disinfection are carried out in time and in sections, and the efficiency of heat disinfection can be effectively improved.
In some embodiments of the present disclosure, the liquid storage and supply device further includes a spraying device 314 disposed at the top of the liquid storage device 311, and an inlet of the spraying device 314 is connected to an inlet c of the liquid storage device 311. When the liquid storage and supply device is in a circulation heating mode, although the path through which the liquid flows is short, proteins, lipids and other substances generated after the bacteria and viruses lose activity enter the liquid storage device 311 along with the liquid in the circulation heating process and are adsorbed on the inner wall of the liquid storage device 311. Thus, the spray arrangement 314 is arranged to effectively wash off proteins and lipids adsorbed on the inner wall of the reservoir 311 and subsequently to be discharged with the liquid from the discharge line 324 in a cyclic heat disinfection mode.
In some embodiments of the present disclosure, the second valve 323 is a third three-way valve, further comprising a ninth port 7 c;
the liquid storage and supply device further comprises a fourth three-way valve 352 arranged on the liquid inlet pipeline 351 and comprising a tenth valve port 8a, an eleventh valve port 8b and a twelfth valve port 8c, wherein the tenth valve port 8a and the eleventh valve port 8b are arranged on the liquid inlet pipeline 351, the eleventh valve port 8b is closer to the liquid inlet 6c of the liquid storage device 311 than the tenth valve port 8a, and the twelfth valve port 8c of the fourth three-way valve 352 is connected with the ninth valve port 7c of the third three-way valve through a pipeline.
The liquid storage and supply device is in another circulation air elimination mode, at the moment, the first switch valve 362, the seventh port 7a and the ninth port 7c of the third three-way valve, the eighth port 8b and the ninth port 8c of the fourth three-way valve 352 are opened, and the first valve 322, the second switch valve 372, the eighth port 7b of the second valve 323 and the seventh port 8a of the fourth three-way valve 352 are closed. The liquid in the liquid return pipeline 341 can sequentially pass through the pipeline between the fourth three-way valve 352 and the third three-way valve and the liquid inlet pipeline 351 to enter the liquid storage device 311, so that bubbles in the liquid in the pipeline and other equipment can be removed, and the normal work of the hemodialysis system can be guaranteed.
When the liquid storage and supply device is in a back flushing mode, the second switch valve 372, the seventh valve port 7a and the ninth valve port 7c of the third three-way valve, the seventh valve port 8a and the ninth valve port 8c of the fourth three-way valve 352, the first heating device 333 and the second heating device 343 are opened, and the first valve 322, the first switch valve 362, the eighth valve port 7b of the third three-way valve and the eighth valve port 8b of the fourth three-way valve 352 are closed. The heated liquid may enter the filter 38 to backwash the filter 38. For example, with an alkaline solution, bacteria, viruses, and other attachments may be removed from the filter assembly, which may facilitate increasing the useful life of the filter assembly 38.
The liquid storage and supply device provided by the embodiment of the disclosure is a totally enclosed liquid storage and supply system, so that the possibility of entering bacteria is greatly reduced, the dialysis environment is favorably improved, and the dialysis quality is improved; simultaneously, liquid can be at stock solution confession liquid device inner loop flow, can promote the flow of the interior liquid of stock solution device under the effect of positive pressure pump, and under the effect of negative pressure pump, the bubble in the liquid is broken in the pipeline, then gaseous gas is discharged from the gas vent of stock solution device, and liquid gets into the stock solution device through circulation feed liquor pipeline afterwards, and reciprocating cycle is many times, then can realize the getting rid of to the interior bubble of liquid in the pipeline, effectively reduces the internal risk of patient's bubble entering in dialysis process. The liquid storage and supply device is applied to a centralized liquid supply system, and is beneficial to ensuring the life health of patients.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
All the embodiments in the present specification are described in a related manner, and the same and similar parts among the embodiments may be referred to each other, and each embodiment focuses on the differences from the other embodiments.
The above description is only for the preferred embodiment of the present disclosure, and is not intended to limit the scope of the present disclosure. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present disclosure are included in the scope of protection of the present disclosure.
Claims (14)
1. A stirring device, comprising:
the bottom of the stirring barrel is provided with a liquid outlet;
at least one ejector group arranged in the stirring barrel, wherein each ejector group comprises two ejectors with parallel and opposite ejection directions; and the number of the first and second groups,
and the inlet of the stirring pump is connected with the liquid outlet, and the outlet of the stirring pump is connected with the inlets of the two ejectors.
2. The stirring device of claim 1, wherein the stirring barrel comprises a cylindrical section and a conical section which are arranged from top to bottom in sequence, and the bottom of the cylindrical section is connected with the large end of the conical section;
the liquid outlet is arranged at the small end of the conical section.
3. The stirring device of claim 2, further comprising a circulation pipe, a first branch pipe and a second branch pipe; the inlet of the circulating pipe is connected with the outlet of the stirring pump, and the outlet of the circulating pipe is connected with the inlet of the first branch pipe and the inlet of the second branch pipe;
one of the at least one injector group is located at a transition junction of the barrel section and the cone section;
the outlet of the first branch pipe is connected with the inlet of one ejector in one ejector group, and the outlet of the second branch pipe is connected with the inlet of the other ejector in one ejector group.
4. The blending device of claim 3, further comprising a screen; the filter screen sets up in the toper section and be located the top of tip.
5. The blending device of claim 4, further comprising a center tube;
the central pipe is positioned above the filter screen and communicated with the first branch pipe and the second branch pipe;
the bottom of the central tube is provided with a plurality of through holes corresponding to the filter screen.
6. The stirring device of claim 5, wherein said through holes are kidney-shaped holes and are two in number;
the plane where the generatrix at the bottom of the central tube and the axis of the central tube are located is a plane B; the two waist-shaped holes are symmetrical about the plane B;
the two ends of the waist-shaped hole are respectively provided with an arc section, and the plane where the central axes of the two arc sections are located is an A plane; the included angle between the plane A and the plane B is less than or equal to 20 degrees.
7. The mixing device of any one of claims 1 to 6, wherein the two eductors are venturi eductors.
8. The stirring device of any one of claims 1 to 6, wherein the stirring barrel is provided with a plurality of flow-inhibiting plates on the barrel wall, and the plurality of overflow plates are arranged along the circumferential direction of the barrel wall and extend along the vertical direction.
9. The stirring device of claim 8 wherein the flow-inhibiting plate is toothed at the end remote from the wall of the stirring barrel;
in two adjacent flow restraining plates, the gear teeth of one flow restraining plate and the gear teeth grooves of the other flow restraining plate are located at the same height.
10. The stirring device according to any one of claims 3 to 6, wherein at least one of a resistance heater, a temperature sensor, and a conductivity probe is provided on the circulation pipe.
11. A centralized liquid supply system, comprising the stirring device of any one of claims 1 to 10.
12. The centralized liquid supply system of claim 11, further comprising a filter device for filtering the dialysate output by the agitation device;
the filtering device includes:
a filter assembly comprising a first fluid port and a second fluid port;
the working liquid inlet pipeline is connected with the first liquid port;
the ultrafiltration component comprises a third liquid port, a fourth liquid port and a fifth liquid port;
the first connecting pipeline is communicated with the second liquid port and the third liquid port;
the first three-way valve comprises a first valve port, a second valve port and a third valve port, the first valve port and the second valve port are arranged on the first connecting pipeline, and the first valve port is closer to the second liquid port;
the working solution pipeline is connected with the fourth solution port;
the back washing pump is arranged on the working solution making pipeline, and the liquid outlet side is closer to the fourth liquid port than the liquid inlet side;
the flushing liquid inlet pipeline is connected with the part of the first connecting pipeline, which is positioned between the second liquid port and the first valve port;
the positive flushing liquid discharge pipeline is connected with the part of the working solution pipeline, which is positioned between the fourth liquid port and the back flushing pump;
the back flushing drainage pipeline is connected with the fifth liquid port;
and the ultrafiltration return pipeline is connected to the back-washing liquid discharge pipeline.
13. The centralized liquid supply system of claim 12, further comprising a post-stage liquid distribution delivery system connected to the working liquid line of the filter apparatus;
the post-stage liquid distribution and conveying system comprises a liquid storage device and a plurality of concentrated liquid supply conveying units arranged on different floors, wherein the liquid storage device is arranged below the liquid supply conveying unit on the lowest floor in the plurality of concentrated liquid supply conveying units,
each centralized liquid supply conveying unit comprises:
the pressure relief device is arranged on the conveying pipeline, and the conveying pipeline is connected with the pressure relief device;
the first liquid level detection device and the second liquid level detection device are arranged on the outer wall of the pressure release device, the first liquid level detection device is closer to the top of the pressure release device than the second liquid level detection device, the first liquid level detection device is used for sending a first signal when detecting that the liquid level is not less than the first liquid level height, and the second liquid level detection device is used for sending a second signal when detecting that the liquid level is not less than the second liquid level height;
the controller is electrically connected with the booster pump, the first liquid level detection device and the second liquid level detection device; the controller controls the booster pump to reduce the liquid flow entering the conveying pipeline when receiving the first signal and the second signal, controls the booster pump to keep the liquid flow entering the conveying pipeline unchanged when receiving the second signal and not receiving the first signal, and controls the booster pump to increase the liquid flow entering the conveying pipeline when not receiving the first signal and the second signal.
14. The centralized liquid supply system of claim 12, further comprising a liquid storage and supply device connected to the working outlet line of the filter device;
the liquid storage and supply device comprises:
the liquid storage device comprises a liquid outlet and a circulating liquid inlet which are arranged at the bottom, and a liquid inlet and an air outlet which are arranged at the top;
one end of the liquid inlet pipeline is connected with a liquid inlet of the liquid storage device, and the other end of the liquid inlet pipeline is used for introducing liquid;
the exhaust device is connected with an exhaust port of the liquid storage device;
the circulating liquid inlet pipeline is connected with a circulating liquid inlet of the liquid storage device;
the positive pressure pump is arranged on the liquid outlet pipeline, and one end of the liquid outlet pipeline is connected with a liquid outlet of the liquid storage device;
the liquid return pipeline and the negative pressure pump are arranged on the liquid return pipeline, one end of the liquid return pipeline is connected with the circulating liquid inlet pipeline, and the connection position of the liquid return pipeline is far away from the circulating liquid inlet of the liquid storage device than the first valve;
the second valve comprises a seventh valve port and an eighth valve port, and the seventh valve port is connected with the other end of the circulating liquid inlet pipeline;
the liquid level control device comprises a back-stage pipeline and a first switch valve arranged on the back-stage pipeline, wherein one end of the back-stage pipeline is connected with the other end of the liquid outlet pipeline, and the other end of the back-stage pipeline is connected with the other end of the liquid return pipeline.
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