CN110123249A - A kind of nasosinusitis detection device and application method - Google Patents

A kind of nasosinusitis detection device and application method Download PDF

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CN110123249A
CN110123249A CN201910282562.2A CN201910282562A CN110123249A CN 110123249 A CN110123249 A CN 110123249A CN 201910282562 A CN201910282562 A CN 201910282562A CN 110123249 A CN110123249 A CN 110123249A
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patient
oral cavity
nasosinusitis
light source
detector
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CN110123249B (en
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卫晓峰
奥拉夫·格哈德·米内特
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Suzhou Xinengjie Technology Development Co Ltd
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Suzhou Xinengjie Technology Development Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/07Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/233Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the nose, i.e. nasoscopes, e.g. testing of patency of Eustachian tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/24Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the mouth, i.e. stomatoscopes, e.g. with tongue depressors; Instruments for opening or keeping open the mouth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0088Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for oral or dental tissue

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  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Audiology, Speech & Language Pathology (AREA)
  • Otolaryngology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
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  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
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Abstract

The present invention relates to nasosinusitis diagnostic techniques fields, more particularly to a kind of nasosinusitis detection device and application method, aim to solve the problem that the problem of, diagnosis cumbersome to the diagnosis of nasosinusitis and monitoring method complexity has differences according to the judgment of doctors, diagnoses time and the higher cost of nasosinusitis in the prior art, technical points are to include oral cavity optical component, for being plugged in the oral cavity of patient;Light source, positioned at oral cavity optical component distal end and connected by optical fiber, soft tissue for being transmitted to light from light source at the top of patient oral cavity;Detector, for receiving across patient's nasal sinus and leaving the optical signalling of patient tissue;Analyzer is electrically connected with detector, and the electrical signal for will test device offer carries out comparing, analysis and classification reference, to obtain diagnostic data report.The present invention is more portable, strong applicability, Shou Zhongguang, easy to operate, without special conditions for diagnostics and training on operation, can carry out nasosinusitis detection at any time.

Description

A kind of nasosinusitis detection device and application method
Technical field
The present invention relates to nasosinusitis diagnostic techniques fields, and in particular to a kind of nasosinusitis detection device and application method.
Background technique
It is well known that nasosinusitis is commonly called as brain leakage, Chinese medicine is nasosinusitis.It is a kind of common rhinopathy of clinic, can be with a nasal sinus Individually occur, can also be fallen ill simultaneously with several nasal sinus.The acute sinusitis overwhelming majority is caused by seriously catching cold, because of systemic resistance power Difference causes germ to invade nasal sinus, causes the acute of sinus mucosa in addition local a variety of causes keeps the access of nasal sinus and nasal cavity unsmooth Inflammation, or even nasal sinus empyema is formed, symptom is nasal obstruction, rhinorrhea and hyposphresia etc., sometimes with apparent headache.
Currently, chronic nasosinusitis has been more universal one of chronic disease, usually by unsolved Acute sinus Inflammation is evolved, the main reason is that failing early period to provide Accurate Diagnosis and complete treatment.In the prior art to the master of nasosinusitis Diagnosing with monitoring method includes: 1.X ray;2, ultrasonic scanning;3.CT and MRT, wherein can be according to behaviour using radioscopic image There are great differences for the judgement of work person, cannot provide accurate result;Then lack sensibility and specificity using ultrasonic scanning, Observation based on symptom does not provide consistent or standardized measurement;In addition, relatively expensive using CT and MRT, it is difficult to be used for subsequent Follow-up investigations, and because thering is radiation or contrast agent to should not be used in children or Pregnant women.
Therefore, now urgently a kind of simple possible, diagnosis is accurate, can reduce detection nasosinusitis correlation time and cost Nasosinusitis detection device and application method.
Summary of the invention
Therefore, the technical problem to be solved in the present invention is that overcoming in the prior art to the diagnosis of nasosinusitis and monitoring method Complicated cumbersome, diagnosis has differences according to the judgment of doctors, diagnoses the defect of the time and higher cost of nasosinusitis, to provide one Kind nasosinusitis detection device and application method.
The first scheme of the invention provides a kind of nasosinusitis detection device, comprising:
Oral cavity optical component, for being plugged in the oral cavity of patient;
Light source, positioned at the oral cavity optical component distal end and connected by optical fiber, for light to be transmitted from the light source Soft tissue at the top of patient oral cavity;
Detector, for receiving across patient's nasal sinus and leaving the optical signalling of patient tissue, the detector is by optics Signal is converted into electrical signal;
Analyzer is electrically connected with the detector, and the electrical signal for providing the detector carries out data ratio To, analysis and classification reference, with obtain diagnostic data report.
Optionally, it is provided on the arcwall face of the oral cavity optical component arranged symmetrically and corresponding with patient's nasal sinus position logical Hole, the diameter of the through-hole are 2mm.
Optionally, glass stopper is equipped in the through-hole.
Optionally, the oral cavity optical component is equipped with handle, the handle and the oral cavity light close to described optical fiber one end The shield for preventing light from overflowing from patient oral cavity is equipped between department of the Chinese Academy of Sciences's part.
Optionally, the light source includes mixing radiant and double-wavelength light source.
Optionally, the optical wavelength that the double-wavelength light source is transmitted by the optical fiber is between 650nm-1050nm.
Optionally, the detector is camera.
Optionally, the analyzer includes:
Image selecting section comes any of m described resulting output signals of detector as benchmark image signal Selection, meanwhile, the m-1 resulting output signals of detector are selected as overlapping picture signal;
The m-1 overlapping picture signals and the benchmark image Signal averaging are imaged image combining unit;
The m-1 overlapping picture signals and the benchmark image Signal separator are imaged in image difference portion;
Analysis portion acquires the data in described image combining unit and described image difference portion, and statisticallys analyze to be diagnosed Data report.
Optionally, the light source, detector, host is provided on the outside of analyzer, the side of the host is equipped with diagnosis Data display interface and operation button.
Second scheme of the present invention additionally provides a kind of application method based on above-mentioned nasosinusitis detection device, comprising:
S1: the oral cavity optical component is plugged in the oral cavity of patient, makes to be affixed at the top of its arcwall face and patient oral cavity It closes, it is ensured that the through-hole is corresponding with patient's nasal sinus position;
S2: the image not exposed when the light source is closed is shot by the detector, to receive across patient's nasal sinus And the optical signalling of patient tissue is left, and the optical signal conversion is therewith sent to electrical signal at electrical signal Storage in the analyzer;
S3: opening the light source and selects mixing radiant, is directly toward patient's nasal sinus position by optical fiber transmission Radiation, illuminates the maxillary sinus of patient in a diffuse way;
S4: shooting the light source by the detector and select the image of mixing radiant irradiation, to receive across trouble Person's nasal sinus and the optical signalling for leaving patient tissue, and by the optical signal conversion at electrical signal, therewith electrical signal It is sent to storage in the analyzer;
S5: opening the light source and selects double-wavelength light source, takes combination of the wave-length coverage between 650nm-1050nm, It is transmitted and is divided by the optical fiber and be directly toward the radiation of patient's nasal sinus position at least twice, illuminate the upper jaw of patient in a diffuse way Sinus;
S6: shooting the image that the light source selects double-wavelength light source irradiation by the detector, to receive across trouble Person's nasal sinus and the optical signalling for leaving patient tissue, and by the optical signal conversion at electrical signal, therewith electrical signal It is sent to storage in the analyzer;
S7: by the image selecting section inside the analyzer, by appointing in the m resulting output signals of detector One selects as benchmark image signal, meanwhile, using the m-1 resulting output signals of detector as overlapping image Signal selects;
The m-1 overlapping picture signals and the benchmark image Signal averaging are imaged using described image combining unit;
The m-1 overlapping picture signals and the benchmark image Signal separator are imaged using described image difference portion;
S8: the data in described image combining unit and described image difference portion are acquired by the analysis portion, and are statisticallyd analyze To obtain diagnostic data report.
Technical solution of the present invention has the advantages that
1. nasosinusitis detection device of the invention, because light can travel to facial group of patient easily by nasal sinus Knit, and since fluid can reduce the intensity of transmitted light and change the pattern of transmitted light in sinus caused by infection, thus doctor with May infer that by means of the image of detector shooting, and by analysis after device processing the health status of nasal sinus with for diagnostic purposes and Therapeutic advance is monitored, therefore, in order to accurately measure the health status of nasal sinus, first by above-mentioned oral cavity optical component insertion patient mouthful In chamber, wherein diaphanous spot towards below maxillary sinus upper palate region place, by patient or doctor push this oral cavity optical component with Nasal sinus position at the top of oral cavity is in close contact, and then opens light source, to pass through optical signal transmission fiber to oral cavity optical component Diaphanous spot, illuminate the soft tissue at the top of patient oral cavity in a diffuse way, and then allow detector with set time node into The light that row Image Acquisition, i.e. capture penetrate patient's nasal sinus and cheek, and by this optical signal conversion at electrical signal, finally by Analyzer carries out comparing, analysis and classification according to the electrical signal that detector provides and refers to, that is, uses tissue spectrum technology The absorption spectrum of the fluid or biomembrane in sinus is separated, and it is handled by various imaging algorithms, forms imaging data Library allows doctor and target data to compare to identify hydrops in sinus, inflamed mucous membranes swelling degree, to obtain diagnostic data report.
2. nasosinusitis detection device of the invention is provided with arranged symmetrically and and patient on the arcwall face of oral cavity optical component The corresponding through-hole in nasal sinus position carries out optical transport using through-hole, so that oral cavity optical component be avoided to fill in the inclination behind oral cavity It places, asymmetric irradiation is prevented with this.
3. nasosinusitis detection device of the invention, the setting of glass stopper is that mouth intracavity liquid is penetrated into oral cavity in order to prevent Optical component causes unnecessary error, meanwhile, patient oral cavity can be illuminated by way of diffusion convenient for light shot from the light source The soft tissue at top reduces the illumination uncertainty occurred when oral cavity optical component is directly contacted with oral cavity top with this and can be changed Property.
4. nasosinusitis detection device of the invention, the setting of handle, in order to which patient or doctor insert oral cavity optical component Into oral cavity, and the nasal sinus position at the top of oral cavity optical component and oral cavity is pushed to be in close contact;The setting of shield, prevents light from trouble It overflows in person oral cavity.
5. nasosinusitis detection device of the invention, light source includes mixing radiant and double-wavelength light source, in multispectral imaging In setting, common biomedicine spectrographic technique can be used for quantitative determining endogenous chromophore and the fluorogen (liquid i.e. in nasal sinus Body), and switch between white light and dual wavelength light, it is compared using the data repeatedly measured, so that image quality is more preferable, It can exclude influence of the ambient light to image.
6. nasosinusitis detection device of the invention, the setting of analyzer, when light source transformation, multipass detector is with solid The Image Acquisition of angle is fixed in timing intermediate node, is overlapped point further according to pixel method or region analysis method to important area From, can get the lighting pattern of patient with clearly find out fluid in sinus as a result, these pattern forms can show the solution of patient Cut open structure and physiology stopping state, such as thin osteoplaque can transmit more light at cheekbone, image shows thicker, and bottom hydrops Maxillary sinus distribution of light intensity it is weaker, while when fluid or biomembrane are stacked on maxillary sinus, can change the shape of lighting pattern, thus Based on typical equal parametric shapes pattern, it is able to carry out the normal subtle quantitative comparison between illness of nasal sinus.
7. diagnostic data display interface is arranged in the side of host in nasosinusitis detection device of the invention, the setting of host And operation button, so that more portable, strong applicability, Shou Zhongguang, easy to operate, without special conditions for diagnostics and operation training Instruction, can carry out nasosinusitis detection at any time.
8. the application method of nasosinusitis detection device of the invention has filled up the technological gap between CT and ultrasound diagnosis, Effective supplement patient of existing diagnostic method be can be used as without exposing under the radiation, also do not need special inspection chamber, non-intruding Property method and simple operability be easier to be received, while also not needing special training medical worker, can be used as it is effective, The Auxiliary support and supplement with follow-up examination are accurately diagnosed for the first time.
Detailed description of the invention
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution in the prior art Embodiment or attached drawing needed to be used in the description of the prior art be briefly described, it should be apparent that, it is described below Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor It puts, is also possible to obtain other drawings based on these drawings.
Fig. 1 is the overall structure diagram of the nasosinusitis detection device of one embodiment of the present invention;
Fig. 2 is the rearview of the nasosinusitis detection device of one embodiment of the present invention;
Fig. 3 is the partial structure diagram of the nasosinusitis detection device of one embodiment of the present invention;
Fig. 4 is the internal module connection schematic diagram of the nasosinusitis detection device of one embodiment of the present invention.
Description of symbols:
1, oral cavity optical component;11, through-hole;13, glass stopper;14, handle;15, shield;2, light source;21, optical fiber;3, Detector;4, analyzer;41, image selecting section;42, image combining unit;43, image difference portion;44, analysis portion;5, host; 51, diagnostic data display interface;52, operation button.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and It is not used in the restriction present invention.
A kind of nasosinusitis detection device as shown in Figure 1 and Figure 4, including is used to be plugged in the intraoral oral cavity optics of patient The distal end of component 1, the oral cavity optical component 1 is connected with light source 2 by optical fiber 21, light can be transferred to oral cavity optics from light source 2 Component 1 illuminates the soft tissue at the top of patient oral cavity, such as maxillary sinus position in a diffuse way;2 side of light source is provided with detector 3, which is used to receive across patient's nasal sinus and leave the optical signalling of patient tissue, and converts optical signals into electricity Signal is learned, meanwhile, detector 3 is also electrically connected with analyzer 4, and analyzer 4 is counted according to the electrical signal that detector 3 provides According to comparison, analysis and classification reference, to obtain diagnostic data report.Because light can travel to patient's by nasal sinus easily Facial tissue, and since fluid can reduce the intensity of transmitted light and change the pattern of transmitted light in sinus caused by infection, so The image that doctor relies on detector 3 to shoot, and device 4 may infer that the health status of nasal sinus for diagnosing by analysis after handling Purpose and monitoring therapeutic advance.Therefore, in order to accurately measure the health status of nasal sinus, first by above-mentioned oral cavity optical component 1 It is inserted into patient oral cavity, wherein diaphanous spot is placed towards the upper palate region below maxillary sinus, pushes this oral cavity by patient or doctor Nasal sinus position at the top of optical component 1 and oral cavity is in close contact, and then opens light source 2, is arrived to transmit optical signal by optical fiber 2 The diaphanous spot of oral cavity optical component 1 illuminates the soft tissue at the top of patient oral cavity in a diffuse way, and then allow detector 3 with Set time node carry out Image Acquisition, i.e., capture penetrate patient's nasal sinus and cheek light, and by this optical signal conversion at Electrical signal finally carries out comparing, analysis and classification according to the electrical signal that detector 3 provides by analyzer 4 and refers to, i.e., Using the absorption spectrum of fluid or biomembrane in tissue spectrum technology (such as diffusion spectroscopic methodology) separation sinus, and by it is various at As algorithm handles it, imaging data library is formed, allows doctor and target data to compare to identify that hydrops in sinus, inflammation are viscous Film swelling degree, to obtain diagnostic data report.
As shown in Figure 3 and Figure 4,1 surface of oral cavity optical component be formed with matched arcwall face at the top of patient oral cavity, with symbol Oral cavity Curvature varying is closed, illumination error is effectively reduced.Simultaneously as upper left jaw nasal sinus and upper right jaw nasal sinus are by nasal cavity and nose First separates, and when oral cavity optical component 1 is placed on the center line below nasal cavity, light field is easy to produce asymmetric illumination figure Case, the light through diffusing out are easy to the amesiality or other side, so to solve this problem, the arc of optical component 1 in oral cavity Through-hole 11 arranged symmetrically and corresponding with patient's nasal sinus position is provided on shape face, the diameter of through-hole 11 is 2mm, passes through through-hole 11 Carrying out optical transport prevents asymmetric irradiation so that oral cavity optical component 1 be avoided to fill in the slant setting behind oral cavity with this.
As shown in figure 3, be provided with glass stopper 13 in through-hole 11, the setting of glass stopper 13 is mouth intraluminal fluid in order to prevent Body is penetrated into oral cavity optical component 1, causes unnecessary error, meanwhile, the side that diffusion can be passed through convenient for the light projected from light source 2 Formula illuminates the soft tissue at the top of patient oral cavity, the photograph occurred when being reduced and directly contacted at the top of oral cavity optical component 1 and oral cavity with this Bright uncertain and changeability.
As shown in figure 3, oral cavity optical component 1 is provided with handle 14 close to 12 one end of optical fiber, in order to which patient or doctor will Oral cavity optical component 1 is inserted in oral cavity, and the nasal sinus position at the top of oral cavity optical component 1 and oral cavity is pushed to be in close contact;In addition, The shield 15 for preventing light from overflowing from patient oral cavity is equipped between the handle 14 and oral cavity optical component 1, meanwhile, when oral cavity optical section Part 1 it is accurate in place after, shield 15 is placed exactly on the outside of the lip that will be blocked at light leakage, plays locating effect.
As shown in figure 4, light source 2 includes mixing radiant and double-wavelength light source, white diode, light emitting diode can be selected Or laser is detected as light source 2 with directing light to the specific region of nasal sinus.In this embodiment of the invention, preferably Light emitting diode can produce the light in NIR spectra, and wave-length coverage is between 650nm-1050nm, and type, wavelength, quantity are not It is limited.Since white light covers 600 to 1000nm all relevant wavelengths, it can get all related letters about nasosinusitis disease Breath, on the other hand, under discrete wavelength, intensity wants much higher, and gained picture quality is higher.Therefore, it is arranged in multispectral imaging In, common biomedicine spectrographic technique can be used for quantitative determining endogenous chromophore and fluorogen (liquid i.e. in nasal sinus), And switch between white light and dual wavelength light, is compared using the data repeatedly measured, so that image quality is more preferable, it can Exclude influence of the ambient light to image.
As shown in figure 4, detector 3 be camera, the type of camera without limitation, in some embodiments, camera Can be compatible with wifi, automatically transmit data, such as the mobile device of built-in camera, can be used for image capture, display and Storage.In addition, camera is configured as that the image of all wavelengths can be captured, and it is arranged with high ISO, it can be achieved that data Quick Acquisition.
When using the naked LED array light source directly contacted with oral cavity, due to LED a part and human body sinus tissue Be in close contact and another part not with sinus tissue be in close contact, cause illuminate image readability can be determined according to luminaire Position position and change, therefore be difficult to generate uniform square when using naked LED, so that the setting of oral cavity optical component 1 is must It wants.Meanwhile when the inside of oral cavity optical component 1 is arranged in light source 2, this structure cannot provide between mouth and electronic component Safe enough guarantee, and light source 2 is opened for a long time can generate heat transfer, the detection experience of patient is influenced, thus such as Fig. 1 institute Show, light source 2 is set in vitro, optical signal transmission is carried out by optical fiber 21, can effectively solve the problems, such as this.
As shown in figure 4, analyzer 4 includes by any of m resulting output signal of detector 3 as benchmark image Signal selects, meanwhile, the image selection of selection is carried out using m-1 resulting output signal of detector 3 as overlapping picture signal Portion 41;M-1 is overlapped the image combining unit 42 of picture signal and the imaging of benchmark image Signal averaging;By m-1 overlay chart The image difference portion 43 being imaged as signal and benchmark image Signal separator;Acquire image combining unit 42 and described image difference portion 43 Data, and statistically analyze with obtain diagnostic data report analysis portion 44.In this embodiment of the invention, that is, m 4 ought not When exposure, light source 2 use white light, light source 2 that wavelength is used to use wavelength for 650nm, light source 2 as 1050nm, pass through detection respectively The Image Acquisition of angle is fixed with set time node for device 3, further according to pixel method or region analysis method to important area into Row superposition separation can get the lighting pattern of patient clearly to find out the result of fluid in sinus.These pattern forms can be shown The anatomical structure and physiology stopping state of patient, such as thin osteoplaque can transmit more light at cheekbone, image show it is thicker, and The maxillary sinus distribution of light intensity of bottom hydrops is weaker, while when fluid or biomembrane are stacked on maxillary sinus can change the shape of lighting pattern Shape is able to carry out the normal subtle quantitative comparison between illness of nasal sinus to wait parametric shapes pattern based on typical.
As depicted in figs. 1 and 2, light source 2, detector 3, analyzer 4 outside be provided with host 5, the side of host 5 is equipped with Diagnostic data display interface 51 and operation button 52, so that more portable, strong applicability, Shou Zhongguang, easy to operate, without special Conditions for diagnostics and training on operation, nasosinusitis detection can be carried out at any time.
Invention further discloses the application methods based on above-mentioned nasosinusitis detection device, comprising the following steps:
S1: oral cavity optical component 1 is plugged in the oral cavity of patient, makes to fit at the top of its arcwall face and patient oral cavity, Ensure that through-hole 11 is corresponding with patient's nasal sinus position;
S2: the image not exposed when being closed by 3 photographic light sources 2 of detector, to receive across patient's nasal sinus and leave The optical signalling of patient tissue, and electrical signal is converted optical signals into, electrical signal is sent to 4 memory of analyzer therewith Storage;
S3: opening light source 2 and selects mixing radiant, is directly toward the radiation of patient's nasal sinus position by the transmission of optical fiber 21, The maxillary sinus of patient is illuminated in a diffuse way;
S4: selecting the image of mixing radiant irradiation by 3 photographic light sources 2 of detector, to receive across patient's nasal sinus And the optical signalling of patient tissue is left, and convert optical signals into electrical signal, electrical signal is sent to analysis therewith Storage in device 4;
S5: it opens light source 2 and selects double-wavelength light source, take combination of the wave-length coverage between 650nm-1050nm, lead to It crosses the transmission of optical fiber 21 and divides and be directly toward the radiation of patient's nasal sinus position at least twice, illuminate the maxillary sinus of patient in a diffuse way;
S6: selecting the image of double-wavelength light source irradiation by 3 photographic light sources 2 of detector, to receive across patient's nasal sinus And the optical signalling of patient tissue is left, and convert optical signals into electrical signal, electrical signal is sent to analysis therewith Storage in device 4;
S7: by the image selecting section 41 inside analyzer 4, by any of m resulting output signal of detector 3 It is selected as benchmark image signal, meanwhile, the m-1 resulting output signal of detector 3 is selected as overlapping picture signal It selects;
M-1 overlapping picture signal and benchmark image Signal averaging are imaged using image combining unit 42;
M-1 overlapping picture signal and benchmark image Signal separator are imaged using image difference portion 43;
S8: the data in image combining unit 42 and image difference portion 43 are acquired by analysis portion 44, and are statisticallyd analyze to obtain Diagnostic data report.
This nasosinusitis detection device and application method, because light can travel to facial group of patient easily by nasal sinus It knits, and since fluid can reduce the intensity of transmitted light and change the pattern of transmitted light in sinus caused by infection, so for standard Oral cavity optical component 1, is inserted into patient oral cavity by the really health status of measurement nasal sinus first, and wherein diaphanous spot is towards under maxillary sinus The upper palate region of side is placed, and pushes the nasal sinus position at the top of this oral cavity optical component 1 and oral cavity to be in close contact by patient or doctor, Then when do not expose, light source 2 uses white light, light source 2 uses wavelength to be cut when using wavelength for 650nm, light source 2 as 1050nm It changes, to transmit optical signal to the diaphanous spot of oral cavity optical component 1 by optical fiber 2, is illuminated at the top of patient oral cavity in a diffuse way Soft tissue, and then allow detector 3 that the Image Acquisition of angle is fixed with set time node, i.e. capture penetrates patient The light of nasal sinus and cheek, and by this optical signal conversion at electrical signal, finally using tissue spectrum technology (such as diffused light Spectrometry) fluid or biomembrane in separation sinus absorption spectrum, and it is handled by various imaging algorithms, forms imaging Database is overlapped separation to important area further according to pixel method or region analysis method, can get patient lighting pattern with Clearly find out fluid in sinus as a result, nasal sinus is normal and illness to be able to carry out based on typical equal parametric shapes pattern Between subtle quantitative comparison so that doctor and target data compare to identify hydrops in sinus, inflamed mucous membranes swelling degree, with It is reported to accurate diagnostic data.
Obviously, the above embodiments are merely examples for clarifying the description, and does not limit the embodiments.It is right For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of variation or It changes.There is no necessity and possibility to exhaust all the enbodiments.And it is extended from this it is obvious variation or It changes still within the protection scope of the invention.

Claims (10)

1. a kind of nasosinusitis detection device characterized by comprising
Oral cavity optical component (1), for being plugged in the oral cavity of patient;
Light source (2) is located at the distal end of the oral cavity optical component (1) and is connected by optical fiber (21), for by light from the light Source (2) is transmitted to the soft tissue at the top of patient oral cavity;
Detector (3), for receiving across patient's nasal sinus and leaving the optical signalling of patient tissue, the detector (3) is by light It learns signal and is converted into electrical signal;
Analyzer (4) is electrically connected with the detector (3), for counting the electrical signal that the detector (3) provide According to comparison, analysis and classification reference, to obtain diagnostic data report.
2. a kind of nasosinusitis detection device according to claim 1, which is characterized in that the oral cavity optical component (1) Through-hole (11) arranged symmetrically and corresponding with patient's nasal sinus position is provided on arcwall face, the diameter of the through-hole (11) is 2mm.
3. a kind of nasosinusitis detection device according to claim 2, which is characterized in that be equipped with glass in the through-hole (11) Plug (13).
4. a kind of nasosinusitis detection device according to claim 1, which is characterized in that the oral cavity optical component (1) is leaned on Nearly described optical fiber (21) one end is equipped with handle (14), and being equipped between the handle (14) and the oral cavity optical component (1) prevents The shield (15) that light is overflowed from patient oral cavity.
5. a kind of nasosinusitis detection device according to claim 1, which is characterized in that the light source (2) includes mixed light Light source and double-wavelength light source.
6. a kind of nasosinusitis detection device according to claim 5, which is characterized in that the double-wavelength light source passes through described The optical wavelength of optical fiber (21) transmitting is between 650nm-1050nm.
7. a kind of nasosinusitis detection device according to claim 1, which is characterized in that the detector (3) is camera.
8. a kind of nasosinusitis detection device according to claim 1, which is characterized in that the analyzer (4) includes:
Image selecting section (41) regard any of m resulting output signals of the detector (3) as benchmark image signal It selects, meanwhile, the m-1 detector (3) resulting output signals are selected as picture signal is overlapped;
The m-1 overlapping picture signals and the benchmark image Signal averaging are imaged image combining unit (42);
The m-1 overlapping picture signals and the benchmark image Signal separator are imaged in image difference portion (43);
Analysis portion (44) acquires the data in described image combining unit (42) and described image difference portion (43), and statistically analyze with Obtain diagnostic data report.
9. a kind of nasosinusitis detection device according to claim 1 to 8, which is characterized in that the light source (2), detector (3), be provided with host (5) on the outside of analyzer (4), the side of the host (5) is equipped with diagnostic data and shows Interface (51) and operation button (52).
10. a kind of application method of nasosinusitis detection device, which is characterized in that based on a kind of nasal sinus as claimed in claim 9 Scorching detection device, method include:
S1: the oral cavity optical component (1) is plugged in the oral cavity of patient, makes to be affixed at the top of its arcwall face and patient oral cavity It closes, it is ensured that the through-hole (11) is corresponding with patient's nasal sinus position;
S2: the image not exposed when the light source (2) is closed is shot by the detector (3), to receive across patient's nose Sinus and the optical signalling for leaving patient tissue, and the optical signal conversion therewith sends electrical signal at electrical signal Storage in the analyzer (4);
S3: opening the light source (2) and selects mixing radiant, is directly toward patient's nasal sinus portion by the optical fiber (21) transmission Position radiation, illuminates the maxillary sinus of patient in a diffuse way;
S4: shooting the light source (2) by the detector (3) and select the image of mixing radiant irradiation, thus receive across Patient's nasal sinus and the optical signalling for leaving patient tissue, and the optical signal conversion therewith believes electricity at electrical signal Number it is sent to storage in the analyzer (4);
S5: opening the light source (2) and select double-wavelength light source, take combination of the wave-length coverage between 650nm-1050nm, It is transmitted and is divided by the optical fiber (21) and be directly toward the radiation of patient's nasal sinus position at least twice, illuminate patient's in a diffuse way Maxillary sinus;
S6: shooting the image that the light source (2) selects double-wavelength light source irradiation by the detector (3), thus receive across Patient's nasal sinus and the optical signalling for leaving patient tissue, and the optical signal conversion therewith believes electricity at electrical signal Number it is sent to storage in the analyzer (4);
S7: by the internal image selecting section (41) of the analyzer (4), by the m resulting output signals of the detector (3) Any of selected as benchmark image signal, meanwhile, using the m-1 detector (3) resulting output signals as Picture signal is overlapped to select;
The m-1 overlapping picture signals and the benchmark image Signal averaging are imaged using described image combining unit (42);
The m-1 overlapping picture signals and the benchmark image Signal separator are imaged using described image difference portion (43);
S8: by the analysis portion (44) acquisition described image combining unit (42) and the data in described image difference portion (43), and Statistical analysis is to obtain diagnostic data report.
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