CN109345458A - One kind splicing ultrasound image method based on improved harris Corner Detection - Google Patents

One kind splicing ultrasound image method based on improved harris Corner Detection Download PDF

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Publication number
CN109345458A
CN109345458A CN201811246341.1A CN201811246341A CN109345458A CN 109345458 A CN109345458 A CN 109345458A CN 201811246341 A CN201811246341 A CN 201811246341A CN 109345458 A CN109345458 A CN 109345458A
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image
class
ultrasound image
ultrasound
value
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CN201811246341.1A
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倪昕晔
孙鸿飞
林涛
高留刚
谢凯
眭建锋
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Changzhou Second Peoples Hospital
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Changzhou Second Peoples Hospital
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Priority to CN201811246341.1A priority Critical patent/CN109345458A/en
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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T3/00Geometric image transformations in the plane of the image
    • G06T3/40Scaling of whole images or parts thereof, e.g. expanding or contracting
    • G06T3/4038Image mosaicing, e.g. composing plane images from plane sub-images
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00Image enhancement or restoration
    • G06T5/70Denoising; Smoothing
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/11Region-based segmentation
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/136Segmentation; Edge detection involving thresholding
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/30Determination of transform parameters for the alignment of images, i.e. image registration
    • G06T7/33Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2200/00Indexing scheme for image data processing or generation, in general
    • G06T2200/32Indexing scheme for image data processing or generation, in general involving image mosaicing
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10132Ultrasound image
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30096Tumor; Lesion

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

The invention discloses a kind of Harris operator ultrasound image joining methods chosen based on adaptive threshold T, the following steps are included: S1. image obtains: in CT simulator locating room and therapeutic room, successively acquisition CT and ultrasound image, this studies all image datas volume data acquired from three abdominal post-operation tumor patient scanning, every patient chooses 10 ultrasounds and the layer images of CBCT, S2. the image obtained in S1 is pre-processed: 400 × 400 two-dimensional ultrasonic image is divided into 4 × 4 non-overlapping subgraphs first before doing ultrasound image splicing, calculate angle point receptance function R Distribution value in subgraph, it prepares to obtain adaptive threshold, realize the smooth transition between two width ultrasound stitching images, eliminate splicing gap, the accuracy of image mosaic is better than traditional The method of Harris Corner Detection.

Description

One kind splicing ultrasound image method based on improved harris Corner Detection
Method field
The present invention relates to a kind of ultrasound image joining methods, and in particular to one kind is based on improved harris Corner Detection Splice ultrasound image method.
Background method
In clinical radiation therapy, conical beam CT (CBCT) is used as common image guidance device, has been widely used in image and has drawn Lead radiotherapy and adaptive radiation therapy.However CBCT soft tissue resolution is low, and marksmanship gunnery hardening effect, electron scattering cause Artifact phenomenon make rebuild after picture quality it is poor.Radiotherapy technology, ultrasonic in combination CBCT are guided compared to traditional CBCT The image guidance techniques for carrying out the verifying of pendulum position can reduce the Set-up errors of abdominal tumor.But utilize the imaging of ultrasonic guidance radiotherapy Image acquired in equipment is narrow beam imaging, is only its localized imaging region compared to CBCT image, for pelvic cavity and abdominal tumor, By tumor target and organ cannot be jeopardized be entirely included in areas imaging, cause CBCT on the basis of tumor target GTV with The image of ultrasonic both modalities which carries out generating registration error with punctual, and then influences the order of accuarcy that patient finally puts position verifying. Therefore, the areas imaging for increasing ultrasound image is the solution for improving ultrasonic in combination CBCT guidance pendulum position verifying precision.
Image mosaic technology, which refers to, is combined into one group of image with lap by image registration, image co-registration The new images at the big visual angle of one width, interior new images include all pixels information spliced in preceding image.Corner Detection is spelled as image The common method of connection technology, can be divided into following two categories: one, the Corner Detection based on image border, such method is mainly according to inspection The edge crossing point measured determines angle point, depends on image segmentation and edge extracting, and computationally intensive and serious forgiveness is smaller, Use scope is relatively limited to, and edge detection operator mainly includes LOG operator, Canny operator and Sobel operator etc.;Two, based on figure As the Corner Detection of gray scale, by searching the pixel in image at the maximum of local gray level variation as angle point, based on ash Spending detective operators mainly includes Moravec operator, Harris operator and Susan operator etc..Wherein Harris operator is used as and is based on Image grayscale detects the common method of angle point, insensitive to the variation of image rotation, grey scale change and noise, and calculates relatively simple A large amount of characteristic point that is single, being extracted in complicated human tissue structure image.But traditional Harris Corner Detection Algorithm Threshold value need to be manually set when extracting angle point, does not have scale invariability, if threshold value setting is excessive, will lead to lacking for part angle point It loses, if threshold value setting is too small, will lead to a large amount of pseudo- angle points of generation.
Therefore, we design a kind of based on improved harris Corner Detection splicing ultrasound image method.
Summary of the invention
The purpose of the present invention is to solve disadvantages present in existing joining method, and the one kind proposed is based on improved Harris Corner Detection splices ultrasound image method.
To achieve the goals above, present invention employs following method schemes:
One kind splicing ultrasound image method based on improved harris Corner Detection, comprising the following steps:
S1. image obtains: in CT simulator locating room and therapeutic room, successively acquiring CT and ultrasound image.
S2. the image obtained in S1 is pre-processed: first by the two of 400 × 400 before doing ultrasound image splicing Ultrasound Image Segmentation is tieed up into 4 × 4 non-overlapping subgraphs, calculates angle point receptance function R Distribution value in subgraph, to obtain adaptive thresholding Value is prepared.
S3. using the improved Harris angle point merging algorithm for images chosen based on adaptive threshold to pretreated in S2 Image is screened: dividing principle using OTUS, the angle point number of detection is determined by optimal T value and splices two width ultrasound figures Picture.
Preferably, it is improved to traditional based on Harris corner feature registration Algorithm in the S3, if R value is i Pixel number be ni, sum of all pixels N, piIndicate the probability that i occurs in 4 × 4 subgraphs, specific algorithm are as follows:
Given initial threshold T, is divided into two class of A, B for the pixel in image:
A=0,1 ..., T } B=T+1, T+2 ..., K } (3)
The then probability that this A class and B class pixel R value occur are as follows:
R value mean value in A class and B class and entire 4 × 4 subgraph is respectively as follows:
The variance of A class and B class is respectively as follows:
The between-group variance of A class and B classAnd intra-class varianceFor
OTUS is divided principle and is pointed out,Smaller, the R value in group is more similar,Bigger, two groups of difference is bigger, because Corresponding T is as optimal threshold, objective function when maximum are as follows:
The invention has the advantages that: the abdomens for using improved Harris Corner Detection Algorithm being ultrasonic in combination CBCT guidance Tumour puts position verifying and provides the ultrasound image information in the wide visual field, and realizes the smooth transition between two width ultrasound stitching images, Image slot is eliminated, the accuracy of image mosaic splices the method for ultrasound image better than traditional Harris Corner Detection.
Detailed description of the invention
The following further describes the present invention with reference to the drawings.
Fig. 1 is ultrasound image stitching image.Scheme a, b is ultrasound image to be spliced, and figure c is to utilize the improved angle Harris The splicing ultrasound image that point detection algorithm obtains, figure d are the splicing ultrasound image that traditional Harris Corner Detection Algorithm obtains;
Fig. 2 is the lab diagram for splicing ultrasound image and goldstandard ultrasound image.Fig. 2 a is improved Harris Corner Detection The pixel difference figure of splicing ultrasound image and goldstandard ultrasound image that algorithm obtains, Fig. 2 b are the calculation of tradition Harris Corner Detection The pixel difference figure of splicing ultrasound image and goldstandard ultrasound image that method obtains
Fig. 3 is the lab diagram that the spliced ultrasound of patient is registrated fusion with CBCT.Fig. 3 a, 3b are respectively that bladder maximum is cut Two ultrasound images to be spliced in face, Fig. 3 c, 3d are respectively to utilize improved Harris Corner Detection Algorithm and tradition The ultrasound image that Harris Corner Detection Algorithm is spliced, Fig. 3 e are the CBCT image of level identical as ultrasound image, Fig. 3 f Fused image is registrated with CBCT for ultrasound.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, carries out to the method scheme in the embodiment of the present invention clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
Embodiment:
(1) image obtains: before acquiring image, need to be carried out with calibration body mould to indoor laser lamp coordinate system and ultrasonic probe Calibration, these calibrations may insure the coordinate position of each 3D ultrasound voxel of system acquisition relative to indoor laser lamp coordinate system It is known.CT and ultrasound image in therapeutic room.After to be calibrated, ultrasound and CBCT image are successively acquired.
(2) image preprocessing: 400 × 400 two-dimensional ultrasonic image is divided into first before doing ultrasound image splicing 4 × 4 non-overlapping subgraphs calculate angle point receptance function R Distribution value in subgraph, prepare to obtain adaptive threshold.
(3) the improved Harris angle point merging algorithm for images chosen based on adaptive threshold: thought using the segmentation of OTSU Think, R value replacement pixels value is responded with the angle point of pixel each in image, iterates and calculates T value, is constantly rejected on edge Pseudo- angle point determines the angle point number of detection eventually by optimal T value and splices two width ultrasound images.
Steps are as follows: setting R value as the number of the pixel of i is ni, sum of all pixels N, piIndicate that i occurs in 4 × 4 subgraphs Probability, formula is as follows:
Given initial threshold T, is divided into two classes for the pixel in image:
A=0,1 ..., T } B=T+1, T+2 ..., K } (3)
The then probability that these two types of pixel R values occur are as follows:
R value mean value in A class and B class and entire 4 × 4 subgraph is respectively as follows:
The variance of A class and B class is respectively as follows:
The between-group variance of A class and B classAnd intra-class varianceFor
OTSU points out,Smaller, the R value in group is more similar,Bigger, two groups of difference is bigger, becauseInstitute when maximum Corresponding T is as optimal threshold, objective function are as follows:
(4) improved Harris Corner Detection stitching algorithm is obtained into ultrasound image and original Harris detection method respectively Compared with the ultrasound image of acquisition is made the difference with goldstandard ultrasound image, pixel difference figure more tends to blue, then two width comparison charts Difference it is smaller.It is registrated using the spliced ultrasound image of improved method with CBCT, verifying patient abdomen histoorgan exists The integrality being imaged in ultrasound image.
The splicing ultrasound image that the application is obtained by the Harris angular-point detection method chosen based on adaptive threshold at Picture has widened the areas imaging of ultrasound, solves the defect of ultrasonic device narrow beam imaging.It is obtained using improved Harris method Splicing ultrasound image and goldstandard ultrasound image degree of similarity it is higher, and realize putting down between two width ultrasound stitching images Degree of slipping over, eliminates gap, and the accuracy of image mosaic splices the method for ultrasound image better than traditional Harris Corner Detection.
More than, it is merely preferred embodiments of the present invention, but scope of protection of the present invention is not limited thereto, it is any Be familiar with the method personnel in this method field the invention discloses method within the scope of, scheme and its invention according to the method for the present invention Design is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (2)

1. one kind splices ultrasound image method based on improved harris Corner Detection, which comprises the following steps:
S1. image obtains: in CT simulator locating room and therapeutic room, successively acquiring CT and ultrasound image;
S2. the image obtained in S1 is pre-processed: first that 400 × 400 two dimension is super before doing ultrasound image splicing Acoustic image is divided into 4 × 4 non-overlapping subgraphs, calculates angle point receptance function R Distribution value in subgraph, does to obtain adaptive threshold Prepare;
S3. using the improved Harris angle point merging algorithm for images chosen based on adaptive threshold to image pretreated in S2 It is screened: principle is divided using OTUS, the angle point number of detection is determined by optimal T value and splices two width ultrasound images.
2. it is according to claim 1 a kind of based on improved harris Corner Detection splicing ultrasound image method, it is described It is improved to traditional based on Harris corner feature registration Algorithm in S3, if the number for the pixel that R value is i is ni, as Plain sum is N, piIndicate the probability that i occurs in 4 × 4 subgraphs, specific algorithm are as follows:
Given initial threshold T, is divided into two class of A, B for the pixel in image:
A=0,1 ..., T } B=T+1, T+2 ..., K } (3)
The then probability that this A class and B class pixel R value occur are as follows:
R value mean value in A class and B class and entire 4 × 4 subgraph is respectively as follows:
The variance of A class and B class is respectively as follows:
The between-group variance of A class and B classAnd intra-class varianceFor
OTUS is divided principle and is pointed out,Smaller, the R value in group is more similar,Bigger, two groups of difference is bigger, becauseIt is maximum When corresponding T as optimal threshold, objective function are as follows:
CN201811246341.1A 2018-10-25 2018-10-25 One kind splicing ultrasound image method based on improved harris Corner Detection Pending CN109345458A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113609943A (en) * 2021-07-27 2021-11-05 东风汽车有限公司东风日产乘用车公司 Finger vein recognition method, electronic device and storage medium

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US20080095421A1 (en) * 2006-10-20 2008-04-24 Siemens Corporation Research, Inc. Registering 2d and 3d data using 3d ultrasound data
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113609943A (en) * 2021-07-27 2021-11-05 东风汽车有限公司东风日产乘用车公司 Finger vein recognition method, electronic device and storage medium
CN113609943B (en) * 2021-07-27 2024-05-17 东风汽车有限公司东风日产乘用车公司 Finger vein recognition method, electronic device and storage medium

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Application publication date: 20190215