CN109010298B - 一种二甲双胍格列吡嗪复方组合物及其制备方法 - Google Patents
一种二甲双胍格列吡嗪复方组合物及其制备方法 Download PDFInfo
- Publication number
- CN109010298B CN109010298B CN201811009420.0A CN201811009420A CN109010298B CN 109010298 B CN109010298 B CN 109010298B CN 201811009420 A CN201811009420 A CN 201811009420A CN 109010298 B CN109010298 B CN 109010298B
- Authority
- CN
- China
- Prior art keywords
- glipizide
- metformin hydrochloride
- magnesium stearate
- coating layer
- tablet core
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811009420.0A CN109010298B (zh) | 2018-08-31 | 2018-08-31 | 一种二甲双胍格列吡嗪复方组合物及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811009420.0A CN109010298B (zh) | 2018-08-31 | 2018-08-31 | 一种二甲双胍格列吡嗪复方组合物及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN109010298A CN109010298A (zh) | 2018-12-18 |
CN109010298B true CN109010298B (zh) | 2020-10-27 |
Family
ID=64625999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201811009420.0A Active CN109010298B (zh) | 2018-08-31 | 2018-08-31 | 一种二甲双胍格列吡嗪复方组合物及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109010298B (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110215437B (zh) * | 2019-07-18 | 2021-10-08 | 北京中惠药业有限公司 | 一种盐酸二甲双胍片及其制备方法 |
CN113616613A (zh) * | 2021-08-30 | 2021-11-09 | 河南合智医药科技有限公司 | 一种治疗糖尿病用药二甲双胍格列吡嗪复方片剂及其制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA03008997A (es) * | 2001-04-10 | 2004-02-12 | Sun Pharmaceutical Ind Ltd | Composicion de liberacion por impulso temporizado. |
US7183321B2 (en) * | 2001-12-17 | 2007-02-27 | Bristol-Myers Squibb Company | Antidiabetic formulation and method |
CN101810628B (zh) * | 2010-04-13 | 2012-05-23 | 北京四环科宝制药有限公司 | 二甲双胍格列吡嗪片及其制备方法 |
CN103494816B (zh) * | 2013-09-29 | 2019-06-14 | 威海迪素制药有限公司 | 一种治疗糖尿病的药物组合物 |
WO2015071889A1 (en) * | 2013-11-18 | 2015-05-21 | Ranbaxy Laboratories Limited | Oral compositions of saxagliptin |
CN104473894A (zh) * | 2014-12-18 | 2015-04-01 | 浙江华海药业股份有限公司 | 一种盐酸吡格列酮载药包衣制剂及其制备方法 |
CN104644633A (zh) * | 2015-01-30 | 2015-05-27 | 华润赛科药业有限责任公司 | 一种高稳定性氨氯地平阿托伐他汀钙片的制备方法 |
CN105250231B (zh) * | 2015-11-02 | 2020-05-12 | 北京泰德制药股份有限公司 | 一种含有依托考昔的药物组合物及其制备方法 |
-
2018
- 2018-08-31 CN CN201811009420.0A patent/CN109010298B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
CN109010298A (zh) | 2018-12-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2003292443A (ja) | メトホルミンおよびグリベンクラミドの組み合わせを含んでなる固体経口投与形態 | |
CN105213346B (zh) | 一种含有盐酸西那卡塞的药物组合物及其制备方法 | |
CN102188429A (zh) | 一种治疗糖尿病的药物组合物 | |
CN109010298B (zh) | 一种二甲双胍格列吡嗪复方组合物及其制备方法 | |
CN103520128A (zh) | 一种普拉克索的缓释片剂、制备方法及其用途 | |
JP2019516706A (ja) | ダパグリフロジンの新規な結晶形並びにその製造方法および用途 | |
CN101167731A (zh) | 含有二甲双胍和格列本脲的分散片及其制备方法 | |
CN109925287A (zh) | 一种盐酸赛庚啶片剂及其制备方法 | |
CN106924237B (zh) | 一种含有恩格列净和盐酸二甲双胍的药物组合物 | |
CN112494485A (zh) | 一种沙格列汀和盐酸二甲双胍缓释片 | |
CN111557920A (zh) | 一种含有硫辛酸的片剂及其制备方法 | |
CN103705515B (zh) | 含有瑞格列奈和盐酸二甲双胍的药物组合物的制备方法 | |
CN110585155A (zh) | 一种格列齐特片(ii)及其制备方法 | |
CN113616613A (zh) | 一种治疗糖尿病用药二甲双胍格列吡嗪复方片剂及其制备方法 | |
CN114129528B (zh) | 一种具有临床优势的新型枸橼酸西地那非制剂及其制备工艺与应用 | |
CN113143929B (zh) | 一种西格列汀复方制剂的制备方法 | |
CN114042051A (zh) | 一种含有西格列汀和二甲双胍的药物组合物及其制备方法 | |
CN117084990A (zh) | 一种含有己酮可可碱的缓释片的制备方法 | |
CN104224783B (zh) | 一种含瑞格列奈二甲双胍的药物组合物及其制备方法 | |
WO2021258851A1 (zh) | 一种治疗糖尿病的药物组合物及其制备方法 | |
CN115245495B (zh) | 一种西格列汀二甲双胍片及其制备方法 | |
CN107441051A (zh) | 一种盐酸普罗帕酮微片及其制备方法 | |
CN114306267A (zh) | 一种西格列汀二甲双胍片制剂及其制备方法 | |
CN101168059A (zh) | 一种含有双胍、磺酰脲和噻唑烷二酮的稳定的药物组合物及其制备方法 | |
CN106551927A (zh) | 包含维格列汀和盐酸二甲双胍的药物组合物及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20200902 Address after: 264205 No. 1 South Qingdao Road, Weihai economic and Technological Development Zone, Shandong, China Applicant after: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Applicant after: Dijia Pharmaceutical Group Co.,Ltd. Address before: 264205 South Qingdao Road-1-4, Weihai Economic and Technological Development Zone, Weihai City, Shandong Province Applicant before: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Applicant before: WEIHAI DISU PHARMACEUTICAL Co.,Ltd. |
|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20210622 Address after: No.1 Qingdao South Road, Weihai Economic and Technological Development Zone, Shandong Province Patentee after: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Address before: No.1 Qingdao South Road, Weihai Economic and Technological Development Zone, Shandong Province Patentee before: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Patentee before: Dijia Pharmaceutical Group Co.,Ltd. |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Metformin glipizide compound composition and preparation method thereof Effective date of registration: 20211025 Granted publication date: 20201027 Pledgee: Bank of China Limited Weihai Branch Pledgor: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Registration number: Y2021980010533 |