CN107995862B8 - 包含sglt-2抑制剂之液态药物组合物 - Google Patents
包含sglt-2抑制剂之液态药物组合物 Download PDFInfo
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- CN107995862B8 CN107995862B8 CN201680047192.9A CN201680047192A CN107995862B8 CN 107995862 B8 CN107995862 B8 CN 107995862B8 CN 201680047192 A CN201680047192 A CN 201680047192A CN 107995862 B8 CN107995862 B8 CN 107995862B8
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15182715 | 2015-08-27 | ||
EP15182715.1 | 2015-08-27 | ||
PCT/EP2016/069977 WO2017032799A1 (en) | 2015-08-27 | 2016-08-24 | Liquid pharmaceutical compositions comprising sglt-2 inhibitors |
Publications (3)
Publication Number | Publication Date |
---|---|
CN107995862A CN107995862A (zh) | 2018-05-04 |
CN107995862B CN107995862B (zh) | 2021-10-22 |
CN107995862B8 true CN107995862B8 (zh) | 2021-12-03 |
Family
ID=54010974
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201680047192.9A Active CN107995862B8 (zh) | 2015-08-27 | 2016-08-24 | 包含sglt-2抑制剂之液态药物组合物 |
Country Status (14)
Country | Link |
---|---|
US (2) | US10220017B2 (zh) |
EP (1) | EP3341024B1 (zh) |
JP (2) | JP6682621B2 (zh) |
KR (1) | KR102659761B1 (zh) |
CN (1) | CN107995862B8 (zh) |
AR (1) | AR105844A1 (zh) |
AU (1) | AU2016310535B2 (zh) |
BR (1) | BR112018003749B1 (zh) |
CA (1) | CA2996458C (zh) |
EA (1) | EA201890592A1 (zh) |
MX (1) | MX2018002383A (zh) |
NZ (1) | NZ739429A (zh) |
TW (1) | TWI784929B (zh) |
WO (1) | WO2017032799A1 (zh) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2981269B9 (en) | 2013-04-04 | 2023-12-06 | Boehringer Ingelheim Vetmedica GmbH | Treatment of metabolic disorders in equine animals |
BR112016011564B1 (pt) * | 2013-12-17 | 2021-02-09 | Boehringer Ingelheim Vetmedica Gmbh | usos de inibidores de sglt2 ou formas farmaceuticamente aceitáveis dos mesmos para o tratamento de distúrbios metabólicos em animais felinos |
EP4234012A3 (en) | 2014-01-23 | 2023-09-20 | Boehringer Ingelheim Vetmedica GmbH | Sglt2 inhibitors for treatment of metabolic disorders in canine animals |
NZ723781A (en) | 2014-04-01 | 2022-09-30 | Boehringer Ingelheim Vetmedica Gmbh | Treatment of metabolic disorders in equine animals |
MX2017003716A (es) | 2014-09-25 | 2017-06-30 | Boehringer Ingelheim Vetmedica Gmbh | Tratamiento de combinacion y/o prevencion de transtorno metabolicos en animales equinos. |
EA201890592A1 (ru) | 2015-08-27 | 2018-09-28 | Бёрингер Ингельхайм Ветмедика Гмбх | Жидкие фармацевтические композиции, содержащие ингибиторы sglt-2 |
AU2020394498A1 (en) | 2019-11-28 | 2022-06-09 | Boehringer Ingelheim Vetmedica Gmbh | Use of SGLT-2 inhibitors in the drying-off of non-human mammals |
JP7423800B2 (ja) | 2020-02-17 | 2024-01-29 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | ネコにおける心臓疾患の予防および/または治療のためのsglt-2阻害剤の使用 |
JP2024518644A (ja) * | 2021-05-21 | 2024-05-01 | デーウン ファーマシューティカル カンパニー リミテッド | イナボグリフロジンを含むイヌ科動物の糖尿病予防又は治療用薬学組成物 |
KR20240041966A (ko) | 2021-07-28 | 2024-04-01 | 베링거잉겔하임베트메디카게엠베하 | 고양이를 제외한 비인간 포유류, 특히 개에서 심장 질환의 예방 및/또는 치료를 위한 sglt-2 억제제의 용도 |
KR20240040106A (ko) | 2021-07-28 | 2024-03-27 | 베링거잉겔하임베트메디카게엠베하 | 비-사람 포유류에서 신장 질환의 예방 및/또는 치료를 위한 sglt-2 억제제의 용도 |
US20240269105A1 (en) | 2021-07-28 | 2024-08-15 | Boehringer Ingelheim Vetmedica Gmbh | Use of sglt-2 inhibitors for the prevention and/or treatment of hypertension in non-human mammals |
KR20230112426A (ko) * | 2022-01-20 | 2023-07-27 | 주식회사 대웅제약 | 이나보글리플로진을 포함하는 개과 동물의 비만 예방 또는 치료용 약학 조성물 |
TW202412756A (zh) | 2022-05-25 | 2024-04-01 | 德商百靈佳殷格翰維美迪加股份有限公司 | 包含sglt-2抑制劑之水性醫藥組合物 |
WO2024116198A1 (en) * | 2022-12-02 | 2024-06-06 | Syri Research Private Limited | Oral liquid formulation of empagliflozin or its pharmaceutically acceptable salt thereof |
US20240307628A1 (en) | 2023-03-06 | 2024-09-19 | Boehringer Ingelheim Vetmedica Gmbh | Systems and methods for delivery of liquid pharmaceutical compositions in particular comprising one or more sglt-2 inhibitor(s) |
Citations (2)
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WO2009143020A1 (en) * | 2008-05-22 | 2009-11-26 | Bristol-Myers Squibb Company | Method for treating hyperuricemia employing an sglt2 inhibitor and composition containing same |
WO2015110402A1 (en) * | 2014-01-23 | 2015-07-30 | Boehringer Ingelheim Vetmedica Gmbh | Treatment of metabolic disorders in canine animals |
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JP2020111598A (ja) | 2020-07-27 |
BR112018003749B1 (pt) | 2023-10-31 |
JP6682621B2 (ja) | 2020-04-15 |
KR20180039727A (ko) | 2018-04-18 |
US20190142787A1 (en) | 2019-05-16 |
JP6936893B2 (ja) | 2021-09-22 |
TWI784929B (zh) | 2022-12-01 |
JP2018525424A (ja) | 2018-09-06 |
KR102659761B1 (ko) | 2024-04-24 |
WO2017032799A1 (en) | 2017-03-02 |
CN107995862A (zh) | 2018-05-04 |
AU2016310535B2 (en) | 2021-08-19 |
CA2996458A1 (en) | 2017-03-02 |
US10709683B2 (en) | 2020-07-14 |
CN107995862B (zh) | 2021-10-22 |
BR112018003749A2 (pt) | 2018-09-25 |
EP3341024A1 (en) | 2018-07-04 |
MX2018002383A (es) | 2018-04-11 |
US20170056366A1 (en) | 2017-03-02 |
CA2996458C (en) | 2024-04-23 |
EP3341024B1 (en) | 2024-10-09 |
AR105844A1 (es) | 2017-11-15 |
NZ739429A (en) | 2023-03-31 |
US10220017B2 (en) | 2019-03-05 |
AU2016310535A1 (en) | 2018-02-22 |
TW201717966A (zh) | 2017-06-01 |
EA201890592A1 (ru) | 2018-09-28 |
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