CN107754433B - Filtering device for micro device - Google Patents
Filtering device for micro device Download PDFInfo
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- CN107754433B CN107754433B CN201711179803.8A CN201711179803A CN107754433B CN 107754433 B CN107754433 B CN 107754433B CN 201711179803 A CN201711179803 A CN 201711179803A CN 107754433 B CN107754433 B CN 107754433B
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- filter
- joint
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- micro device
- flows
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- 238000001914 filtration Methods 0.000 title claims abstract description 24
- 239000007788 liquid Substances 0.000 claims abstract description 17
- 238000004806 packaging method and process Methods 0.000 claims description 8
- 239000000084 colloidal system Substances 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 238000012423 maintenance Methods 0.000 abstract description 5
- 238000009434 installation Methods 0.000 abstract description 3
- 238000012864 cross contamination Methods 0.000 abstract description 2
- 230000010354 integration Effects 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 230000002035 prolonged effect Effects 0.000 abstract description 2
- 230000006872 improvement Effects 0.000 description 8
- 239000000463 material Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 238000010923 batch production Methods 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- Filtering Materials (AREA)
Abstract
The present invention provides a filtration apparatus for a micro device for filtering a liquid flowing into the micro device, the filtration apparatus comprising: the filter is fixed on the micro device and comprises an input end and an output end; a connection portion connecting an output end of the filter and a first end of the micro device; the liquid flows into the filter from the input end of the filter, flows out from the output end of the filter, flows through the connecting part and flows into the micro device. After the technical scheme is adopted, the integrated integration of the filtering device and the micro device is realized, and the mass production is facilitated; the installation and maintenance are convenient, the service life of the micro device is prolonged, and the cost is saved; the filter device is not beyond the original size of the micro device, so that the filter device is convenient to use in a narrow working environment; avoiding the risk of cross contamination of large devices in the prior art.
Description
Technical Field
The invention relates to the field of micro-electromechanical equipment, in particular to a filtering device for a micro device.
Background
Microelectromechanical devices are widely used in various industries, particularly in the field of biotechnology, often requiring the use of channels on the order of micrometers, for example, by adding a mixture homogeneously mixed with a DNA buffer to a microreaction tank fabricated on a solid support, also known as a microdevice, and allowing the mixture involved in the biochemical reaction to repeatedly pass through the solid support, where the "microreaction tank" is a microchannel. The micro-channels are often used for simulating capillary networks, and have a plurality of problems in application, namely, the micro-channels are very easy to block due to the narrow reasons, and the mixture flows, so that the service life of the product is low, and the product is easy to damage.
The prior art adopts a cleaning mode of repeated positive pressure and negative pressure through reagents to solve the problem of microchannel blockage. Another solution in the prior art is to add a filtering device at the front end of the micro device, however, the implementation of this method requires to add a lot of additional spare parts and power devices for supporting, including pump valves, air sources, screw rods, software control drives and the like, and the disadvantage is that the device has a complex structure, unstable working conditions, difficult later maintenance and higher maintenance cost.
Therefore, a novel filtering device for micro devices is needed, and compared with the prior art, the novel filtering device is simpler in structure, easy to replace and maintain, and low in maintenance cost.
Disclosure of Invention
In order to overcome the technical defects, the invention aims to provide a filter device for a micro device, which has the technical effects of simplifying the structure of the filter device and being easy to maintain by arranging a filter and a connecting part.
The invention discloses a filtering device for a micro-device, which is used for filtering liquid flowing into the micro-device, and comprises:
the filter is fixed on the micro device and comprises an input end and an output end;
a connection portion connecting an output end of the filter and a first end of the micro device;
the liquid flows into the filter from the input end of the filter, flows out from the output end of the filter, flows through the connecting part and flows into the micro device.
Preferably, the filter and the micro device are both cuboid, and the cross-sectional area of the filter on the horizontal plane is smaller than the cross-sectional area of the micro device on the horizontal plane.
Preferably, the connection part includes:
the connecting end of the first connector is connected with the output end of the filter;
the middle pipeline is U-shaped and comprises a first connecting end and a second connecting end which are connected with the leading-out end of the first joint;
and the connecting end of the second connector is connected with the first end of the micro device, and the leading-out end of the second connector is connected with the second connecting end of the intermediate pipeline.
Preferably, the filtering device further comprises:
the connecting end of the third joint is connected with the input end of the filter, and the leading-out end of the third joint is connected with the inlet of an external pipeline;
and the connecting end of the fourth joint is connected with the second end of the micro device, and the leading-out end of the fourth joint is connected with the outlet of the external pipeline.
Preferably, the second and fourth joints form first and second bosses around the first and second ends of the micro device;
the first protruding part and the second protruding part clamp and fix the filter provided with the first joint and the third joint.
Preferably, the leading-out ends of the first joint, the second joint, the third joint and the fourth joint are provided with holes, and the middle pipeline and the external pipeline are connected through the holes.
Preferably, the filter is internally provided with a bee net type filter structure made of at least two materials.
Preferably, the filtering device further comprises:
and the packaging part is used for packaging the micro device, the filter and the connecting part inside to form a closed space.
Preferably, the enclosed space is filled with colloid.
After the technical scheme is adopted, compared with the prior art, the method has the following beneficial effects:
1. the integrated integration of the filter device and the micro device is realized, which is beneficial to mass production;
2. the installation and maintenance are convenient, the service life of the micro device is prolonged, and the cost is saved;
3. the filter device is not beyond the original size of the micro device, so that the filter device is convenient to use in a narrow working environment;
4. avoiding the risk of cross contamination of large devices in the prior art.
Drawings
Fig. 1 is a schematic view of a filtration apparatus for microdevices according to a preferred embodiment of the present invention.
Reference numerals:
1-filter, 2-microdevice, 3-connection, 4-first joint, 5-second joint, 6-third joint, 7-fourth joint, 8-intermediate line, 9-inlet of external line, 10-outlet of external line.
Detailed Description
Advantages of the invention are further illustrated in the following description, taken in conjunction with the accompanying drawings and detailed description.
Referring to fig. 1, a schematic structure of a filtering apparatus for a micro device for filtering a liquid flowing into the micro device 2 according to a preferred embodiment of the present invention includes:
filter 1
The filter 1 is fixed on the micro device 2 and comprises an input end and an output end. The filter 1 has a filter structure inside, and can filter out particles or impurities in the liquid. The filter 1 is provided with an input end and an output end, and in operation, the liquid flows in from the input end of the filter 1, is filtered by the filter 1 and flows out from the output end of the filter 1. The filter 1 is arranged on the micro device 2, and can be fixed in an auxiliary manner by using clamping grooves, glue, adhesive tapes and the like.
-a connection 3
The connection 3 connects the output end of the filter 1 and the first end of the micro device 2. The purpose of the connection 3 is to connect the output end of the filter 1 with the first end of the micro-device 2 so that liquid can flow from the output end of the filter 1 to the first end of the micro-device 2. The two ends of the connecting part 3 are respectively fixedly connected with the output end of the filter 1 and the first end of the micro device 2, and maintain a sealing state to prevent liquid leakage.
When the filtering device works, the liquid flows into the filter 1 from the input end of the filter 1, flows out from the output end of the filter 1, flows through the connecting part 3 and flows into the micro device 2. The filter device realizes integrated design and is convenient for batch production.
As a further improvement of the filter device, the filter 1 and the micro-device 2 are rectangular parallelepiped, and the cross-sectional area of the filter 1 on the horizontal plane is smaller than the cross-sectional area of the micro-device 2 on the horizontal plane. The present improvement allows the filter 1 to be smaller in horizontal dimension than the micro-device 2, and to appear as if the micro-device 2 were "backed" against the filter 1, so that the overall size of the filter device is not enlarged in horizontal dimension as compared to the micro-device 2, and the requirement for installation in a narrow working space can be satisfied.
As a further improvement of the filter device, the connecting portion 3 includes:
-a first joint 4
The first connector 4 comprises a connecting end and a leading-out end, and the connecting end of the first connector is connected with the output end of the filter 1. The connecting end of the first connector 4 and the output end of the filter 1 have matched geometric shapes, and the connecting end and the output end can be matched and spliced, so that the liquid can flow into the first connector 4 from the output end of the filter 1. The leading-out end of the first connector 4 can be connected with a pipeline.
Intermediate line 8
The middle pipeline 8 is U-shaped and comprises a first connecting end and a second connecting end which are connected with the leading-out end of the first connector 4. The function of the intermediate line 8 is to connect the first and second connectors 4, 5 and to guide the flow of the liquid from the filter 1 to the micro-device 2.
Second joint 5
The second connector 5 comprises a connection end and a lead-out end, wherein the connection end is connected with the first end of the micro device 2, and the lead-out end is connected with the second connection end of the intermediate pipeline 8. The second connector 5 may have the same or similar structure as the first connector 4.
In this modified embodiment, the connecting portion 3 is three parts, and a connector is used, so that the filter 1 is convenient to assemble and maintain quickly, for example, when the filter 1 is replaced and maintained, the micro device 2 is not required to be disassembled.
As a further improvement of the above-described filter device, the filter device further includes:
third joint 6
The third connector 6 comprises a connecting end and a leading-out end, wherein the connecting end is connected with the input end of the filter 1, and the leading-out end is connected with an inlet 9 of an external pipeline. The third connector 6 may have the same or similar structure as the first connector 4.
Fourth joint 7
The fourth connector 7 comprises a connection end and a lead-out end, wherein the connection end is connected with the second end of the micro device 2, and the lead-out end is connected with an outlet 10 of an external pipeline. The fourth connector 7 may have the same or similar structure as the first connector 4.
The present modified embodiment defines the connection of the filter device to an external conduit, using a third joint 6 and a fourth joint 7, respectively, to an inlet 9 and an outlet 10 of the external conduit. The liquid is circulated through the inlet 9 of the external pipe into the filter 1, then through the intermediate pipe 8, then into the micro device 2, and finally out through the outlet 10 of the external pipe. Therefore, the filtering device can be integrally assembled and disassembled with an external pipeline, and integrated design is realized.
As a further improvement of the above-described filter device, the second joint 5 and the fourth joint 7 enclose the first end and the second end of the micro device 2 to form a first protrusion and a second protrusion. The first and second protrusions clamp and fix the filter 2 to which the first and third connectors 4 and 6 are mounted. The present modified embodiment defines a fixing manner of the filter 1, that is, after the filter 1 is connected to the first connector 4 and the third connector 6, the filter is clamped and fixed as a fixed integral component by the second connector 5 and the fourth connector 7. The implementation of this embodiment has the premise that the second and fourth tabs 5, 7 protrude outwards with respect to the horizontal plane of the micro-device 2, forming first and second bosses capable of clamping the outer edges of the first and third tabs 4, 6 when the filter 1 is placed on the micro-device 2 together with the first and third tabs 4, 6. In order to better achieve a clamping fixation of the filter 1, the distance between the inner end edges of the second and fourth connectors 5, 7 is equal to the distance between the outer end edges of the first and third connectors 4, 6 when the filter device is assembled.
As a further development of the above-mentioned filter device, the outlet ends of the first, second, third and fourth connectors 4, 5, 6 and 7 are provided with holes through which the intermediate pipe 8 and the external pipe are connected. The improved embodiment limits the leading-out end of each joint, the leading-out end of each joint is provided with a hole, and a pipeline is inserted into the hole to realize connection with the joint. According to the action positions of the different joints, each joint is connected with the middle pipeline 8 and the external pipeline respectively. The technical characteristics allow the pipeline to be flexibly assembled with the connector, so that the filter device is more convenient to assemble and disassemble.
As a further improvement of the filter device, the filter 1 is internally provided with a bee net type filter structure made of at least two materials. The improved embodiment further defines the internal structure of the filter 1, and is composed of at least two materials, and the filter structure is a honeycomb structure, i.e. a net-shaped honeycomb structure.
As a further improvement of the filter device, the filter device further includes:
-a packaging part
The packaging part packages the micro device 2, the filter 1 and the connecting part 3 inside the micro device to form a closed space. The enclosure may be a plastic wrap covering the filter device and being tied around the external pipe inlet 9 and the external pipe outlet 10 so that the filter device only allows liquid to pass in and out through the external pipe and not into the surface crevices of other components. The packaging part can also protect the filtering device, prevent the interference of external impurities and avoid being corroded by corrosive substances.
As a further improvement of the above-mentioned filtering device, the enclosed space is filled with a gel. After the colloid is filled, no air exists between the outer surface of the filtering device and the packaging part, so that an effective sealing environment is formed, and the liquid smoothly flows into the filter 1.
It should be noted that the embodiments of the present invention are preferred and not limited in any way, and any person skilled in the art may make use of the above-disclosed technical content to change or modify the same into equivalent effective embodiments without departing from the technical scope of the present invention, and any modification or equivalent change and modification of the above-described embodiments according to the technical substance of the present invention still falls within the scope of the technical scope of the present invention.
Claims (5)
1. A filter device for a micro-device for filtering a liquid flowing into the micro-device, characterized in that,
the filtering device includes:
the filter is fixed on the micro device and comprises an input end and an output end;
a connection portion connecting an output end of the filter and a first end of the micro device;
the liquid flows into the filter from the input end of the filter, flows out from the output end of the filter, flows through the connecting part and flows into the micro device;
the filter and the micro device are both cuboid, and the cross section area of the filter on the horizontal plane is smaller than that of the micro device;
the connection part includes:
the connecting end of the first connector is connected with the output end of the filter;
the middle pipeline is U-shaped and comprises a first connecting end and a second connecting end which are connected with the leading-out end of the first joint;
the connecting end of the second connector is connected with the first end of the micro device, and the leading-out end of the second connector is connected with the second connecting end of the intermediate pipeline;
the connecting end of the third joint is connected with the input end of the filter, and the leading-out end of the third joint is connected with the inlet of an external pipeline;
the connecting end of the fourth joint is connected with the second end of the micro device, and the leading-out end of the fourth joint is connected with the outlet of the external pipeline;
the micro device refers to a solid support with micro reaction channels;
the first joint and the third joint are fixed between the second joint and the fourth joint.
2. A filter device as claimed in claim 1, wherein,
the second joint and the fourth joint surround the first end and the second end of the micro device to form a first protruding part and a second protruding part;
the first protruding part and the second protruding part clamp and fix the filter provided with the first joint and the third joint.
3. A filter device as claimed in claim 2, wherein,
and the leading-out ends of the first joint, the second joint, the third joint and the fourth joint are provided with holes, and the middle pipeline and the external pipeline are connected through the holes.
4. A filter device according to any one of claims 1 to 3,
the filter device further includes:
and the packaging part is used for packaging the micro device, the filter and the connecting part inside to form a closed space.
5. The filter device according to claim 4, wherein,
and colloid is filled in the closed space.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711179803.8A CN107754433B (en) | 2017-11-23 | 2017-11-23 | Filtering device for micro device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711179803.8A CN107754433B (en) | 2017-11-23 | 2017-11-23 | Filtering device for micro device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107754433A CN107754433A (en) | 2018-03-06 |
| CN107754433B true CN107754433B (en) | 2023-09-01 |
Family
ID=61280328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711179803.8A Active CN107754433B (en) | 2017-11-23 | 2017-11-23 | Filtering device for micro device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107754433B (en) |
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2017
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Also Published As
| Publication number | Publication date |
|---|---|
| CN107754433A (en) | 2018-03-06 |
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Effective date of registration: 20230925 Address after: 200331, Room 206, Building 6, No. 2653 Zhenbei Road, Putuo District, Shanghai Patentee after: Ningkasai Technology (Shanghai) Co.,Ltd. Address before: 200025 room 316, 105 Sinan Road, Huangpu District, Shanghai Patentee before: CHANG HE BIO-MEDICAL SCIENCE (YANGZHOU) CO.,LTD. |